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TMC5 Gene

protein-coding   GIFtS: 48
GCID: GC16P019422

Transmembrane Channel-Like 5

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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Transmembrane Channel-Like 51 2
Transmembrane Channel-Like Protein 52

External Ids:    HGNC: 229991   Entrez Gene: 798382   Ensembl: ENSG000001035347   UniProtKB: Q6UXY83   

Export aliases for TMC5 gene to outside databases

Previous GC identifers: GC16P019379 GC16P019434 GC16P019375 GC16P019329 GC16P017959


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for TMC5 Gene:
TMC5 (transmembrane channel-like 5) is a protein-coding gene. An important paralog of this gene is TMC7.

UniProtKB/Swiss-Prot: TMC5_HUMAN, Q6UXY8
Function: Probable ion channel (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000016.9  NT_187260.1  NC_018927.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the TMC5 gene promoter:
         HFH-3   XBP-1   Gfi-1   AREB6   FOXI1   SRY   PPAR-gamma1   PPAR-gamma2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidTMC5 promoter sequence
   Search Chromatin IP Primers for TMC5

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat TMC5


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 16p12.3   Ensembl cytogenetic band:  16p12.3   HGNC cytogenetic band: 16p13.11

TMC5 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TMC5 gene location

GeneLoc information about chromosome 16         GeneLoc Exon Structure

GeneLoc location for GC16P019422:  view genomic region     (about GC identifiers)

Start:
19,421,818 bp from pter      End:
19,510,435 bp from pter
Size:
88,618 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: TMC5_HUMAN, Q6UXY8 (See protein sequence)
Recommended Name: Transmembrane channel-like protein 5  
Size: 1006 amino acids; 114797 Da
Sequence caution: Sequence=BAB14629.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
Secondary accessions: Q68DK8 Q8IY20 Q8NHV6 Q9H8I7
Alternative splicing: 4 isoforms:  Q6UXY8-1   Q6UXY8-2   Q6UXY8-3   Q6UXY8-4   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for TMC5: NX_Q6UXY8

Explore proteomics data for TMC5 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See TMC5 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (4 alternative transcripts): 
    NP_001098718.1  NP_001098719.1  NP_001248770.1  NP_079056.2  

    ENSEMBL proteins: 
     ENSP00000441227   ENSP00000370822   ENSP00000446274   ENSP00000219821   ENSP00000456148  
     ENSP00000454710   ENSP00000461008   ENSP00000458240   ENSP00000379531  

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    Cloud-Clone Corp. Proteins for TMC5

     
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    antibodies-online peptides for TMC5

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    antibodies-online antibodies for TMC5 (11 products) 

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    antibodies-online kits for TMC5 (6 products) 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    1 InterPro protein domain:
     IPR012496 TMC

    Graphical View of Domain Structure for InterPro Entry Q6UXY8

    ProtoNet protein and cluster: Q6UXY8

    1 Blocks protein domain: IPB012496 TMC

    UniProtKB/Swiss-Prot: TMC5_HUMAN, Q6UXY8
    Similarity: Belongs to the TMC family


    Find genes that share domains with TMC5           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: TMC5_HUMAN, Q6UXY8
    Function: Probable ion channel (By similarity)

    Animal Models:

       genOway: Develop your customized and physiologically relevant rodent model for TMC5

    miRNA
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    Block miRNA regulation of human, mouse, rat TMC5 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate TMC5 (see all 13):
    hsa-miR-224 hsa-miR-1231 hsa-miR-4328 hsa-miR-4306 hsa-miR-1236 hsa-miR-223 hsa-miR-4314 hsa-miR-185
    SwitchGear 3'UTR luciferase reporter plasmidTMC5 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat TMC5

    Gene Editing
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    GenScript: all cDNA clones in your preferred vector (see all 3): TMC5 (NM_024780)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TMC5
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TMC5

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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TMC5


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    TMC5_HUMAN, Q6UXY8: Membrane; Multi-pass membrane protein (Potential)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    plasma membrane3
    peroxisome2

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0016021integral component of membrane IEA--

    Find genes that share ontologies with TMC5           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for TMC5
    Interactions:

        Search GeneGlobe Interaction Network for TMC5

    STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

    1 Interacting protein for TMC5 (ENSP000003795314) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    NUMBLENSP000002528914STRING: ENSP00000252891
    About this table

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006811ion transport IEA--

    Find genes that share ontologies with TMC5           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for TMC5



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for TMC5 gene (4 alternative transcripts): 
    NM_001105248.1  NM_001105249.1  NM_001261841.1  NM_024780.4  

    Unigene Cluster for TMC5:

    Transmembrane channel-like 5
    Hs.115838  [show with all ESTs]
    Unigene Representative Sequence: NM_001105248
    11 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000563675 ENST00000541464 ENST00000381414(uc002dgb.4) ENST00000542583(uc010var.2)
    ENST00000219821(uc002dge.4 uc002dgf.4 uc002dgg.4) ENST00000561503
    ENST00000567478(uc002dgd.1) ENST00000564959 ENST00000572147 ENST00000574033
    ENST00000396229(uc010vaq.2 uc002dgc.4)
    miRNA
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    Selected qRT-PCR Assays for microRNAs that regulate TMC5 (see all 13):
    hsa-miR-224 hsa-miR-1231 hsa-miR-4328 hsa-miR-4306 hsa-miR-1236 hsa-miR-223 hsa-miR-4314 hsa-miR-185
    SwitchGear 3'UTR luciferase reporter plasmidTMC5 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for TMC5
    Predesigned siRNA for gene silencing in human, mouse, rat TMC5
    Clone
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    OriGene clones in human, mouse for TMC5 (see all 21)
    OriGene ORF clones in mouse, rat for TMC5
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 3): TMC5 (NM_024780)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TMC5
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TMC5
    Primer
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    OriGene qSTAR qPCR primer pairs in human, mouse for TMC5
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat TMC5
      QuantiTect SYBR Green Assays in human, mouse, rat TMC5
      QuantiFast Probe-based Assays in human, mouse, rat TMC5

    Additional mRNA sequence: 

    AK023655.1 AK093944.1 AK097718.1 AK126270.1 AK131202.1 AK299055.1 AK304431.1 AY236494.1 
    AY263164.1 AY358155.1 BC027602.1 BC038118.2 BC070101.1 CR749359.1 

    17 DOTS entries:

    DT.100680924  DT.95362624  DT.91743046  DT.437478  DT.40122385  DT.99930398  DT.101974817  DT.86841232 
    DT.95369098  DT.99938440  DT.97831802  DT.40263141  DT.91743036  DT.95190193  DT.95369099  DT.91865126 
    DT.95180048 

    Selected AceView cDNA sequences (see all 133):

    AI270207 AI739014 NM_024780 BM978431 BG460713 BC070101 BF064147 AI476009 
    BG184955 AW029127 AY236494 BG184448 AA172244 BG195034 AX748377 AK093944 
    BF062602 BX279606 BM820191 AK023655 AI738488 AA172076 AA877864 CR749359 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for TMC5 (see all 6)    About this scheme

    ExUns: 1a · 1b · 1c · 1d ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15 ^ 16a · 16b ^ 17 ^ 18 ^ 19a · 19b · 19c
    SP1:                                -                                                                                   -                                 
    SP2:                    -           -                                                                                   -                                 
    SP3:                    -                                                                                               -                                 
    SP4:                                -                                                                       -           -                                 
    SP5:                                -                                                                                                                     


    ECgene alternative splicing isoforms for TMC5

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    TMC5 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CTATTTTTAA
    TMC5 Expression
    About this image


    TMC5 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 7) fully expand
     
     Brain (Nervous System)    fully expand to see all 3 entries
             Cerebral Cortex
     
     Testis (Reproductive System)
             Leydig Cells Testis Interstitium
     
     Lung (Respiratory System)
             Alveolar type II cells
     
     Trophoblast (Extraembryonic Tissues)
             Trophoblast Cells Trophoblast
     
     Ovary (Reproductive System)
             Oviduct
    TMC5 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    TMC5 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.115838
        Custom PCR Arrays for TMC5
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    In Situ
    Assay Products:
     

     
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for TMC5 gene from Selected species (see all 14)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Tmc51 , 5 transmembrane channel-like gene family 51, 5 80.3(n)1
    76.12(a)1
      7 (63.44 cM)5
    744241  NM_001105252.11  NP_001098722.11 
     1185972975 
    chicken
    (Gallus gallus)
    Aves TMC51 transmembrane channel-like 5 60.06(n)
    53.09(a)
      416611  XM_414913.4  XP_414913.4 
    lizard
    (Anolis carolinensis)
    Reptilia TMC56
    transmembrane channel-like 5
    54(a)
    1 ↔ 1
    GL344150.1(21-23531)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia tmc51 transmembrane channel-like 5 57.48(n)
    52.4(a)
      100491430  XM_002932210.2  XP_002932256.2 
    zebrafish
    (Danio rerio)
    Actinopterygii LOC5614971 transmembrane channel-like protein 5-like 57.63(n)
    47.92(a)
      561497  XM_684899.4  XP_689991.4 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG32806
    --
    8(a)
    1 → many
    3L(9596701-9607009)
    worm
    (Caenorhabditis elegans)
    Secernentea tmc-26
    tmc-16
    Protein TMC-1 (tmc-1) mRNA, complete cds
    13(a)
    11(a)
    many ↔ many
    many ↔ many
    X(9303724-9310483) WBGene00015177
    X(1163153-1177160) WBGene00020490


    ENSEMBL Gene Tree for TMC5 (if available)
    TreeFam Gene Tree for TMC5 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for TMC5 gene
    TMC72  TMC32  TMC22  TMC82  TMC42  TMC12  TMC62  
    1 SIMAP similar gene for TMC5 using alignment to 5 protein entries:     TMC5_HUMAN (see all proteins):
    TMC6

    Find genes that share paralogs with TMC5           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for TMC5 (see all 2222)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 16 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs572324161,2
    C--17967244(+) TTTTT-/T/TT  
            
    CGAGA
    3 -- int11NA 2
    rs352841931,2
    C--17983620(+) AATAC-/A/AA  
            
    AAAAA
    3 -- int11NA 2
    rs1439522921,2
    --19420130(+) GTGCCC/TGGCTT 2 -- us2k10--------
    rs1841769921,2
    --19420186(+) TGTGAC/TAGGAT 2 -- us2k10--------
    rs1486299461,2
    C--19420208(+) TTAAGG/TCTGCA 2 -- us2k10--------
    rs1886326591,2
    --19420281(+) TAGTTC/TGCTTT 2 -- us2k10--------
    rs1420681271,2
    --19420404(+) CCTGGA/GCTAGA 2 -- us2k10--------
    rs71923121,2
    C,F,A,H--19420427(+) gattaC/Gtgttc 2 -- us2k19Minor allele frequency- G:0.44NA CSA WA EA 370
    rs1911052951,2
    --19420558(+) TTTCAC/GCATGC 2 -- us2k10--------
    rs1820433931,2
    --19420566(+) TGCTGC/TCCAGG 2 -- us2k10--------

    HapMap Linkage Disequilibrium report for TMC5 (19421818 - 19510435 bp)

    Structural Variations
         Database of Genomic Variants (DGV) Selected variations for TMC5 (see all 11):    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2714051CNV Deletion23290073
    esv3792CNV Deletion18987735
    esv2714054CNV Deletion23290073
    esv2116787CNV Deletion18987734
    esv2678457CNV Deletion23128226
    esv2714053CNV Deletion23290073
    nsv436835CNV Insertion17901297
    nsv833162CNV Loss17160897
    esv27832CNV Loss19812545
    nsv905567CNV Gain21882294

    Site Specific Mutation Identification with PCR Assays
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    DNA2.0 Custom Variant and Variant Library Synthesis for TMC5

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    Find genes that share disorders with TMC5           About GenesLikeMe

    Genetic Association Database (GAD): TMC5
    Human Genome Epidemiology (HuGE) Navigator: TMC5 (2 documents)

    Export disorders for TMC5 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for TMC5 gene, integrated from 10 sources (see all 13):
    (articles sorted by number of sources associating them with TMC5)
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    1. TMC and EVER genes belong to a larger novel family, the TMC gene family encoding transmembrane proteins. (PubMed id 12812529)1, 2, 3 Keresztes G.... Heller S. (BMC Genomics 2003)
    2. Characterization of the transmembrane channel-like (TMC) gene family: functional clues from hearing loss and epidermodysplasia verruciformis. (PubMed id 12906855)1, 2, 3 Kurima K.... Griffith A.J. (Genomics 2003)
    3. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (Mol. Med. 2010)
    4. Replication of a genome-wide case-control study of esophageal squamous cell carcinoma. (PubMed id 18649358)1, 4 Ng D....Taylor P.R. (Int. J. Cancer 2008)
    5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    6. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)1, 2 Clark H.F.... Gray A.M. (Genome Res. 2003)
    7. A genome-wide association study of sleep habits and insomnia. (PubMed id 23728906)1 Byrne E.M....Wray N.R. (Am. J. Med. Genet. B Neuropsychiatr. Genet. 2013)
    8. Toward an understanding of the protein interaction network of the human liver. (PubMed id 21988832)1 Wang J....Yang X. (Mol. Syst. Biol. 2011)
    9. The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (BMC Genomics 2007)
    10. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (Genome Res. 2006)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 79838 HGNC: 22999 AceView: TMC5 Ensembl:ENSG00000103534 euGenes: HUgn79838
    ECgene: TMC5 H-InvDB: TMC5

    (According to HUGE)
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    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for TMC5 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for TMC5 gene:
    Search GeneIP for patents involving TMC5

    GeneCards and IP:
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