TMC2 Gene
protein-coding GIFtS: 48
GCID: GC20P002465
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transmembrane channel-like 2(Previous names: transmembrane, cochlear expressed, 2 ) (Previous symbol: C20orf145)
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Aliases for TMC2 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb) About This Section
|
| Aliases |
|---|
| Transmembrane Channel-Like 21 2 | | C20orf1451 2 3 | | DJ686C3.31 | | Transmembrane, Cochlear Expressed, 21 2 | | Transmembrane Cochlear-Expressed Protein 22 3 | | Transmembrane Channel-Like Protein 22 |
Export aliases for TMC2 gene to outside databasesPrevious GC identifers: GC20P002505 GC20P002512 |
Summaries for TMC2 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
| Entrez Gene summary for TMC2: This gene is considered a member of a gene family predicted to encode transmembrane proteins. The specific function ofthis gene is unknown; however, expression in the inner ear suggests that it may be crucial for normal auditoryfunction. Mutations in this gene may underlie hereditary disorders of balance and hearing. (provided by RefSeq, Jul2008) UniProtKB/Swiss-Prot: TMC2_HUMAN, Q8TDI7Function: Probable ion channel required for the normal function of cochlear hair cells Gene Wiki entry for TMC2
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Genomic Views for TMC2 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics) About This Section
| RefSeq DNA sequence:- NC_000020.10 NC_018931.1 NT_011387.8
Regulatory elements: SABiosciences Regulatory transcription factor binding sites in the TMC2 gene promoter: Bach1 Pbx1a Pax-6 Bach2 CUTL1 GATA-1 S8 Nkx6-1 Chx10 Pax-4a Other transcription factors
Search SABiosciences Chromatin IP Primers for TMC2
Epigenetics:
|  | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TMC2 |
Genomic Location: Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 20p13 Ensembl cytogenetic band: 20p13 HGNC cytogenetic band: 20p13TMC2 Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different)

GeneLoc information about chromosome 20 GeneLoc Exon Structure GeneLoc location for GC20P002465: view genomic region
(about GC identifiers)
Start:
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2,517,253 bp from pter |
End:
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2,622,430 bp from pter |
Size:
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105,178 bases |
Orientation:
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plus strand |
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Proteins for TMC2 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
| UniProtKB/Swiss-Prot: TMC2_HUMAN, Q8TDI7 (See
protein sequence)Recommended Name: Transmembrane channel-like protein 2 Size: 906 amino acids; 102610 Da
Subcellular location: Membrane; Multi-pass membrane protein (Potential)
Sequence caution: Sequence=AAQ88976.1; Type=Erroneous initiation; Note=Translation N-terminally extended;Sequence=BAC04423.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
Secondary accessions: Q5JXT0 Q5JXT1 Q6UWW4 Q6ZS41 Q8N9F3 Q9BYN2 Q9BYN3 Q9BYN4 Q9BYN5Alternative splicing: 3 isoforms: Q8TDI7-1 Q8TDI7-3 Q8TDI7-4 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for TMC2: NX_Q8TDI7
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q8TDI7 TMC2 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_542789.2 ENSEMBL proteins: ENSP00000351732 Human Recombinant Protein Products:
Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0016021 | integral to membrane |
IEA | -- | | GO:0032426 | stereocilium bundle tip |
IEA | -- |
TMC2 for ontologies About GeneDecksing
TMC2 Antibody Products: Assay Products for TMC2: |
Protein
Domains / Families for TMC2 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
TMC2 for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry Q8TDI7ProtoNet protein and cluster: Q8TDI7 1 Blocks protein family: IPB012496 TMC
UniProtKB/Swiss-Prot: TMC2_HUMAN, Q8TDI7Similarity: Belongs to the TMC family |
Function for TMC2 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
| Function Summary: UniProtKB/Swiss-Prot: TMC2_HUMAN, Q8TDI7Function: Probable ion channel required for the normal function of cochlear hair cells
Clone Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TMC2 (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TMC2 OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
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Synthesis Service for TMC2 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TMC2  |
In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TMC2 |
Animal Models: 3 MGI mutant phenotypes (inferred from 1 allele ) (MGI details for Tmc2):
TMC2 for phenotypes About GeneDecksing
|
Pathways & Interactions for TMC2 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for TMC2
Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0050910 | detection of mechanical stimulus involved in sensory perception of sound |
IEA | -- | | GO:0060005 | vestibular reflex |
IEA | -- |
TMC2 for ontologies About GeneDecksing
|
Drugs & Compounds for TMC2 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
Browse Tocris compounds for TMC2 Search CenterWatch for drugs/clinical trials and news about TMC2 
|
Transcripts for TMC2 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank, RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
) About This Section
| REFSEQ mRNAs for TMC2 gene: NM_080751.2 Unigene Cluster for TMC2: Transmembrane channel-like 2 Hs.352626 [show with all ESTs]Unigene Representative Sequence: AK1277512 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000358864(uc010zpw.1 uc010zpx.1 uc002wgf.1 uc002wgg.1) ENST00000496948
Clone Products: |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TMC2 (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TMC2 OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: TMC2 (NM_080751) | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for TMC2 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TMC2  |
Additional cDNA sequence: AF417580.2 AK127751.1 AK294013.1 AK309782.1 AK316261.1 4 DOTS entries: DT.100697670 DT.101979004 DT.120802760 DT.99933917 5 AceView cDNA sequences: AF417580 NM_080751 AK127751 AY358613 CD635963 GeneLoc Exon Structure
3 Alternative Splicing Database (ASD) splice patterns (SP) for TMC2 About this scheme
| ExUns: | 1 | ^ | 2 | ^ | 3a | · | 3b | ^ | 4a | · | 4b | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11a | · | 11b | ^ | 12 | ^ | 13 | ^ | 14a | · | 14b | ^ | 15 | ^ | 16a | · | 16b | ^ | 17 | ^ | 18 | ^ | 19 | ^ | 20 | |
| SP1: | |   | |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | - |   | |   | |   | - |   | |   | |   | |   | |   | |
| SP2: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP3: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   |
ECgene alternative splicing isoforms for TMC2
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Expression for TMC2 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| TMC2 expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this imageBioGPS CGAP TAG: GGATACAGTT
About this image See TMC2 Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for TMC2
SOURCE GeneReport for Unigene cluster: Hs.352626 UniProtKB/Swiss-Prot: TMC2_HUMAN, Q8TDI7Tissue specificity: Detected in fetal cochlea SABiosciences Custom PCR Arrays for TMC2
Primer Products: |  | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for TMC2 Browse OriGene validated miRNA SYBR primer pairs
| |  | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat TMC2 | |  | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TMC2 | |  | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TMC2 | In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TMC2 |
Orthologs for TMC2 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for TMC2 gene from 5/17 species (see all 17) About this table
| Organism |
Taxonomic classification |
Gene |
Description |
Human Similarity |
Orthology Type |
Details |
chicken (Gallus gallus) |
Aves |
TMC21 |
transmembrane channel-like 2 |
70.76(n) 72.44(a) |
  |
428456 NM_001039324.1 NP_001034413.1 |
lizard (Anolis carolinensis) |
Reptilia |
TMC26 |
-- |
67(a) |
1 ↔ 1 |
GL343224.1(2086998-2170474) |
zebrafish (Danio rerio) |
Actinopterygii |
LOC5712401 |
transmembrane channel-like gene family 2-like |
63.03(n) 62.32(a) |
  |
571240 XM_694811.4 XP_699903.4 |
fruit fly (Drosophila melanogaster) |
Insecta |
CG32801 |
CG3280 |
48.85(n) 40.23(a) |
  |
39117 NM_140079.3 NP_648336.3 |
worm (Caenorhabditis elegans) |
Secernentea |
T13G4.33 |
-- |
37(a) (best of 2) |
  |
X(1202384-1212051) -- |
ENSEMBL Gene Tree for TMC2 (if available) TreeFam Gene Tree for TMC2 (if available)  |
Paralogs for TMC2 gene(Paralogs according to
1HomoloGene, 2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68) About This Section
| Paralogs for TMC2 gene
- TMC72 TMC32 TMC82 TMC52 TMC62 TMC12 TMC42
2 SIMAP similar genes for TMC2 using alignment to 1 protein entry: TMC2_HUMAN:TMC1 TMC3
TMC2 for paralogs About GeneDecksing
|
Genomic Variants for TMC2 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical significance | Chr 20 pos | Sequence | # | AA Chg | Type | More | # | Allele freq | Pop | Total sample | More |
|---|
HapMap Linkage Disequilibrium report for TMC2 (2517253 - 2622430 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV): 2 variations for TMC2 1 CNV: 73459 1 Indel: 40434  | SABiosciences Cancer Mutation PCR Assays |
|  | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing TMC2 |
|
Disorders
/ Diseases for TMC2 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
TMC2 for disorders About GeneDecksing
OMIM gene information: 606707
OMIM disorders: --
4 diseases for TMC2: About MalaCardsepidermodysplasia verruciformis systemic lupus erythematosus lupus erythematosus hearing loss 1 disease from the University of Copenhagen DISEASES database for TMC2:Epidermodysplasia verruciformis Export disorders for TMC2 gene to outside databases
|
Publications for TMC2 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for TMC2 gene, integrated from 9 sources (see all 11): (articles sorted by number of sources associating them with TMC2) | |  | Utopia: connect your pdf to the dynamic world of online information |
- Dominant and recessive deafness caused by mutations of a novel gene, TMC1, required for cochlear hair-cell function. (PubMed id 11850618)1, 2, 3, 9 Kurima K.... Griffith A.J. (2002)
- Characterization of the transmembrane channel-like (TMC) gene family: functional clues from hearing loss and epidermodysplasia verruciformis. (PubMed id 12906855)1, 3, 9 Kurima K.... Griffith A.J. (2003)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)1, 2 Clark H.F.... Gray A.M. (2003)
- The DNA sequence and comparative analysis of human chromosome 20. (PubMed id 11780052)1, 2 Deloukas P....Rogers J. (2001)
- Differential genetic associations for systemic lupus erythematosus based on anti-dsDNA autoantibody production. (PubMed id 21408207)1 Chung S.A....Criswell L.A. (2011)
- TMC1 but not TMC2 is responsible for autosomal recessive nonsyndromic hearing impairment in Tunisian families. (PubMed id 18259073)1 Tlili A....Masmoudi S. (2008)
- Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (2006)
- TMC and EVER genes belong to a larger novel family, the TMC gene family encoding transmembrane proteins. (PubMed id 12812529)1 Keresztes G.... Heller S. (2003)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
|
External Searches for TMC2 gene
(in PubMed,
OMIM, and NCBI Bookshelf) About This Section
|
|
Genome Databases showing TMC2 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing TMC2 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing TMC2 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL, Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot) About This Section
|
| Name | Description |
| PharmGKB entry for TMC2 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for TMC2 gene: Search GeneIP for patents involving TMC2
GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products for TMC2 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences), In Situ Hybridization Assays from Advanced Cell Diagnostics About This Section
|
 | |
 | |
 |
| | | | Browse OriGene Antibodies | | OriGene shRNA RFP for TMC2 | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for TMC2 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for TMC2 | | OriGene Protein Over-expression Lysate for TMC2 | | Browse OriGene Fluorogenic Cell Assay Kits | | OriGene siRNA for TMC2 | | OriGene 3'-UTR Clone for TMC2 | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TMC2 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TMC2 | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | OriGene Custom Antibody Services for TMC2 | | OriGene Custom Protein Services for TMC2 | | OriGene Custom Immunoassay Development | | |
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| | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat TMC2 | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing TMC2 | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TMC2 | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TMC2 | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TMC2 | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TMC2 |
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 | | TMC2 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TMC2 |
|  |  |  | | | ThermoFisher Antibodies for TMC2 |
| | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TMC2 |
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