Aliases for TMC1 Gene
External Ids for TMC1 Gene
Previous HGNC Symbols for TMC1 Gene
Previous GeneCards Identifiers for TMC1 Gene
This gene is considered a member of a gene family predicted to encode transmembrane proteins. The specific function of this gene is unknown; however, it is known to be required for normal function of cochlear hair cells. Mutations in this gene have been associated with progressive postlingual hearing loss and profound prelingual deafness. [provided by RefSeq, Jul 2008]
GeneCards Summary for TMC1 Gene
TMC1 (Transmembrane Channel-Like 1) is a Protein Coding gene. Diseases associated with TMC1 include dfna36 nonsyndromic hearing loss and deafness and dfnb 7/11 nonsyndromic hearing loss and deafness. GO annotations related to this gene include voltage-gated calcium channel activity. An important paralog of this gene is TMC7.
UniProtKB/Swiss-Prot for TMC1 Gene
Probable ion channel required for the normal function of cochlear hair cells.