TMA7 Gene
protein-coding GIFtS: 34
GCID: GC03P048481
|
|
translation machinery associated 7 homolog (S. cerevisiae)(Previous name: coiled-coil domain containing 72 )
(Previous symbol: CCDC72)
| |
Aliases
for TMA7 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
This gene clusters with an RNA gene
Subcategory (RNA class): lncRNA
Quality score for the ORGUL clustered with this gene is 3
| Aliases |
|---|
| Translation Machinery Associated 7 Homolog (S. Cerevisiae)1 2 | | HSPC0161 | | CCDC721 2 3 | | Translation Machinery-Associated Protein 72 | | Coiled-Coil Domain Containing 721 2 | | Translational Machinery Associated 7 Homolog2 | | Coiled-Coil Domain-Containing Protein 722 3 | | |
| External Ids: | HGNC: 269321 | Entrez Gene: 513722 | Ensembl: ENSG000002321127 | UniProtKB: Q9Y2S63 | | ORGUL members: | |
|---|
| NONCODE:n342502 | |
Export aliases for TMA7 gene to outside databases
|---|
Summaries
for TMA7 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for TMA7 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000003.11 NC_018914.1 NT_022517.18
Regulatory elements:
 Search SABiosciences Regulatory transcription factor binding sites for TMA7
Other transcription factors
Search SABiosciences Chromatin IP Primers for TMA7
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TMA7 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 3p21.31 Ensembl cytogenetic band: 3p21.31 HGNC cytogenetic band: 3p21.31TMA7 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 3 GeneLoc Exon Structure GeneLoc location for GC03P048481: view genomic region
(about GC identifiers)
Start:
|
48,481,667 bp from pter |
End:
|
48,485,616 bp from pter |
Size:
|
3,950 bases |
Orientation:
|
plus strand |
|
Proteins
for TMA7 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: TMA7_HUMAN, Q9Y2S6 (See
protein sequence)Recommended Name: Translation machinery-associated protein 7 Size: 64 amino acids; 7066 Da
Secondary accessions: Q9P052Explore the universe of human proteins at neXtProt for TMA7: NX_Q9Y2S6
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9Y2S6
TMA7 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_057017.1
ENSEMBL proteins: ENSP00000397843
Human Recombinant Protein Products:
TMA7 Antibody Products:
Assay Products for TMA7: |
Protein
Domains /
Families
for TMA7 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
TMA7 for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry Q9Y2S6ProtoNet protein and cluster: Q9Y2S6 UniProtKB/Swiss-Prot: TMA7_HUMAN, Q9Y2S6Similarity: Belongs to the TMA7 family |
Function
for TMA7 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TMA7 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TMA7
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript Custom all cDNA clones Services for TMA7 | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for TMA7 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TMA7 |
1 GenomeRNAi human phenotype for TMA7:
|
Pathways & Interactions
for TMA7 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for TMA7
|
Drugs & Compounds
for TMA7 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for TMA7
Search CenterWatch for drugs/clinical trials and news about TMA7
|
Transcripts
for TMA7 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for TMA7 gene: NM_015933.3 Unigene Cluster for TMA7: Translational machinery associated 7 homolog (S. cerevisiae) Hs.356440 [show with all ESTs]Unigene Representative Sequence: AK1265943 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000479126 ENST00000438607(uc003cte.1) ENST00000477624
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TMA7 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TMA7
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript Custom all cDNA clones Services for TMA7 | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for TMA7 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TMA7 |
Additional cDNA sequence: AF077202.1 AF161448.1 AK126594.1 AY508979.1 AY794023.1 BC001102.2 BC066333.1 BC080531.1 24/31 DOTS entries (see all 31): DT.100045541 DT.91974849 DT.91650308 DT.100043654 DT.91785034 DT.100045538 DT.92003573 DT.95255324 DT.95334529 DT.446693 DT.100691720 DT.120906331 DT.101985407 DT.95334556 DT.91785042 DT.91993133 DT.95334552 DT.95328318 DT.120906198 DT.91747562 DT.100691715 DT.100691737 DT.120906212 DT.65285685 24/519 AceView cDNA sequences (see all 519): BQ637736 BF036382 N78659 AI187137 AI026809 BU579977 AI090805 BF813039 AV653388 AI339191 BQ223023 AA826792 AI709253 AY508979 BE122906 AF161448 AI274885 BF432022 BM786104 AI420748 AI422705 AI282753 BP429087 CB130667
GeneLoc Exon Structure
|
Expression
for TMA7 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| See probesets specificity/sensitivity at GeneAnnot
CGAP TAG: --
See TMA7 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for TMA7
SOURCE GeneReport for Unigene cluster: Hs.356440
SABiosciences Custom PCR Arrays for TMA7
Primer
Products: | | Browse OriGene genome-wide validated SYBR primer pairs
Browse OriGene validated miRNA SYBR primer pairs
| | | Search SABiosciences RT2 qPCR
Primer Assays in human, mouse, rat TMA7 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TMA7 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TMA7 |
Orthologs
for TMA7 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for TMA7 gene from 9/24 species (see all 24) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
mouse
(Mus musculus) |
Mammalia |
Tma71 , 5 |
coiled-coil domain containing 725
translational machinery associated 7 homolog (S. cerevisiae)1 |
94.27(n)1
100(a)1 |
|
9 (59.63 cM)5
661671 NM_183250.21 NP_899073.11
1090779885 |
chicken
(Gallus gallus) |
Aves |
CCDC721 |
coiled-coil domain containing 72 |
78.65(n)
89.06(a) |
|
770887 XM_001234205.2 XP_001234206.1 |
lizard
(Anolis carolinensis) |
Reptilia |
CCDC726 |
-- |
91(a) |
1 ↔ 1 |
2(190373468-190379602) |
tropical clawed frog
(Xenopus tropicalis) |
Amphibia |
Str.62962 |
Transcribed sequence with moderate similarity to protein more |
74.54(n) |
|
137697214 |
zebrafish
(Danio rerio) |
Actinopterygii |
Dr.133342 |
Transcribed sequence with moderate similarity to protein more |
79.01(n) |
|
AL729673.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
CG133641 |
CG13364 |
71.87(n)
75(a) |
|
50364 NM_144243.1 NP_652500.1 |
worm
(Caenorhabditis elegans) |
Secernentea |
F49C12.116 |
Coiled-coil domain-containing protein 72 homolog |
63(a) |
1 ↔ 1 |
IV(9319361-9320127) |
thale cress
(Arabidopsis thaliana) |
eudicotyledons |
AT1G152706AT3G160406 |
Translation machinery associated TMA7 |
59(a)58(a) |
many → 1many → 1 |
1(5250650-5252121) 3(5443091-5443952) |
rice
(Oryza sativa) |
Liliopsida |
---- |
coiled-coil domain-containing protein 72, putative...coiled-coil domain-containing protein 72, putative... |
60(a)54(a) |
many → 1many → 1 |
6(28638654-28640498) 2(3219169-3219516) |
ENSEMBL Gene Tree for TMA7 (if available)
TreeFam Gene Tree for TMA7 (if available) |
Paralogs
for TMA7 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for TMA7 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 3 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for TMA7 (48481667 - 48485616 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for TMA7: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing TMA7 |
|
Disorders
/ Diseases
for TMA7 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Publications
for TMA7 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for TMA7 gene integrated from 9 sources:
(articles sorted by number of sources associating them with TMA7) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells. (PubMed id 11042152)1, 2, 3 Zhang Q.-H.... Chen Z. (2000)
- Apoptosis of the dermal papilla cells of hair follicle associated with the expression of gene HSPCO16 in vitro. (PubMed id 15740594)1, 3, 9 Yang W.B....Ni B. (2005)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Effect of HSPC016 gene expression on the aggregative g rowth of dermal papillae cells. (PubMed id 22571579)1 Song Z....Hao F. (2012)
- Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
- Interactions of pathological hallmark proteins: tubul in polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PubMed id 21832049)1 OlA!h J....OvA!di J. (2011)
- Identification of differentially expressed genes HSPC016 in dermal papilla cells with aggregative behavior. (PubMed id 16096800)1 Zhiqiang S....Chunlan L. (2005)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1 Ota T.... Sugano S. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
|
External Searches for TMA7 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing TMA7 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing TMA7 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing TMA7 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for TMA7 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for TMA7 gene:
Search GeneIP for patents involving TMA7
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for TMA7 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for TMA7 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for TMA7 | | Browse OriGene genome-wide validated SYBR primer pairs | | | OriGene Protein Over-expression Lysate for TMA7 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for TMA7 | | OriGene 3'-UTR Clone for TMA7 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TMA7 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TMA7 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for TMA7 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for TMA7 | | OriGene Custom Protein Services for TMA7 | | | OriGene Custom Immunoassay Development | | |
| |
 |
 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat TMA7 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing TMA7 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TMA7 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TMA7 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TMA7 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TMA7 |
| |
 |  |  |  | |
| | | | Search Tocris compounds for TMA7 |
| |  |  |  |  | | | | |
 |
 |
 |
 | | | TMA7 Proteins, Antibodies, CLIAs, and ELISAs |
| | | |  |  |  | | | | Search ThermoFisher Antibodies for TMA7 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TMA7 |
|
|
|
|
GeneCards Homepage -
Last full update: 18 Mar 2013 -
Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013
View Random Gene
|
Category
|
|
|
von Willebrand factor
|
| GIFtS Group |
|
Developed at the Crown Human Genome Center,
Department of Molecular Genetics,
the Weizmann Institute of Science
Copyright © 1996-2013
, Weizmann Institute of Science. All Rights Reserved.
hostname: 356980-web2.xennexinc.com
index build: 100 solr: 1.4
|
