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Aliases for TMA7 Gene

Aliases for TMA7 Gene

  • Translation Machinery Associated 7 Homolog (S. Cerevisiae) 2 3
  • Coiled-Coil Domain-Containing Protein 72 3 4
  • Coiled-Coil Domain Containing 72 2 3
  • CCDC72 3 4
  • Translational Machinery Associated 7 Homolog 3
  • Translation Machinery-Associated Protein 7 3
  • HSPC016 3

External Ids for TMA7 Gene

Previous HGNC Symbols for TMA7 Gene

  • CCDC72

Summaries for TMA7 Gene

GeneCards Summary for TMA7 Gene

TMA7 (Translation Machinery Associated 7 Homolog (S. Cerevisiae)) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TMA7 Gene

Genomics for TMA7 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for TMA7 Gene

Start:
48,440,257 bp from pter
End:
48,444,208 bp from pter
Size:
3,952 bases
Orientation:
Plus strand

Genomic View for TMA7 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for TMA7 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TMA7 Gene

No data available for Regulatory Elements for TMA7 Gene

Proteins for TMA7 Gene

  • Protein details for TMA7 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9Y2S6-TMA7_HUMAN
    Recommended name:
    Translation machinery-associated protein 7
    Protein Accession:
    Q9Y2S6
    Secondary Accessions:
    • Q9P052

    Protein attributes for TMA7 Gene

    Size:
    64 amino acids
    Molecular mass:
    7066 Da
    Quaternary structure:
    No Data Available

neXtProt entry for TMA7 Gene

Proteomics data for TMA7 Gene at MOPED

Post-translational modifications for TMA7 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for TMA7 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for TMA7 Gene

Domains for TMA7 Gene

Protein Domains for TMA7 Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

Q9Y2S6

UniProtKB/Swiss-Prot:

TMA7_HUMAN :
  • Q9Y2S6
Family:
  • Belongs to the TMA7 family.
genes like me logo Genes that share domains with TMA7: view

No data available for Gene Families and Suggested Antigen Peptide Sequences for TMA7 Gene

Function for TMA7 Gene

Phenotypes for TMA7 Gene

GenomeRNAi human phenotypes for TMA7:
genes like me logo Genes that share phenotypes with TMA7: view

Animal Model Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for TMA7

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for TMA7 Gene

Localization for TMA7 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for TMA7 Gene

Pathways for TMA7 Gene

SuperPathways for TMA7 Gene

No Data Available

Interacting Proteins for TMA7 Gene

STRING Interaction Network Preview (showing 2 interactants - click image to see details)
http://string-db.org/version_10/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000397843%0d%0a9606.ENSP00000276326%0d%0a9606.ENSP00000344818%0d%0a
Selected Interacting proteins: ENSP00000397843 for TMA7 Gene via STRING

Gene Ontology (GO) - Biological Process for TMA7 Gene

None

No data available for Pathways by source for TMA7 Gene

Transcripts for TMA7 Gene

mRNA/cDNA for TMA7 Gene

Unigene Clusters for TMA7 Gene

Translation machinery associated 7 homolog (S. cerevisiae):
Representative Sequences:

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for TMA7

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for TMA7 Gene

No ASD Table

Relevant External Links for TMA7 Gene

GeneLoc Exon Structure for
TMA7
ECgene alternative splicing isoforms for
TMA7

Expression for TMA7 Gene

mRNA expression in normal human tissues for TMA7 Gene

Protein differential expression in normal tissues for TMA7 Gene

This gene is overexpressed in Ovary (8.8).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for TMA7 Gene

SOURCE GeneReport for Unigene cluster for TMA7 Gene Hs.356440

mRNA Expression by UniProt/SwissProt for TMA7 Gene

Q9Y2S6-TMA7_HUMAN
Tissue specificity: Expressed in dermal papilla cells with aggregative behavior.
genes like me logo Genes that share expressions with TMA7: view

Expression partners for TMA7 Gene

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA differential expression in normal tissues for TMA7 Gene

Orthologs for TMA7 Gene

This gene was present in the common ancestor of chordates.

Orthologs for TMA7 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia TMA7 35
  • 92.71 (n)
  • 100 (a)
TMA7 36
  • 100 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Tma7 35
  • 94.27 (n)
  • 100 (a)
Tma7 16
Tma7 36
  • 100 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia TMA7 35
  • 99.48 (n)
  • 100 (a)
TMA7 36
  • 100 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Tma7 35
  • 95.31 (n)
  • 100 (a)
dog
(Canis familiaris)
Mammalia TMA7 36
  • 100 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia TMA7 36
  • 91 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia Str.6296 35
zebrafish
(Danio rerio)
Actinopterygii Dr.13334 35
tma7 36
  • 83 (a)
OneToOne
rainbow trout
(Oncorhynchus mykiss)
Actinopterygii Omy.10125 35
Species with no ortholog for TMA7:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for TMA7 Gene

ENSEMBL:
Gene Tree for TMA7 (if available)
TreeFam:
Gene Tree for TMA7 (if available)

Paralogs for TMA7 Gene

No data available for Paralogs for TMA7 Gene

Variants for TMA7 Gene

Sequence variations from dbSNP and Humsavar for TMA7 Gene

SNP ID Clin Chr 03 pos Sequence Context AA Info Type MAF
rs7126 -- 48,444,085(-) AGGAA(C/T)GACTT utr-variant-3-prime
rs2362441 -- 48,442,272(+) aaaaa(A/G)aaaaa intron-variant
rs3082576 -- 48,443,265(+) AAAAA(-/A)TGCTG intron-variant
rs4490383 -- 48,443,275(+) GGGGT(C/T)GGTGG intron-variant
rs4858820 -- 48,442,607(+) CCACC(A/T)TGCCG intron-variant

Relevant External Links for TMA7 Gene

HapMap Linkage Disequilibrium report
TMA7

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for TMA7 Gene

Disorders for TMA7 Gene

No disorders were found for TMA7 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for TMA7 Gene

Publications for TMA7 Gene

  1. Apoptosis of the dermal papilla cells of hair follicle associated with the expression of gene HSPCO16 in vitro. (PMID: 15740594) Yang W.B. … Ni B. (Exp. Dermatol. 2005) 2 3 23
  2. Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells. (PMID: 11042152) Zhang Q.-H. … Chen Z. (Genome Res. 2000) 2 3 4
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  4. Identification of differentially expressed genes HSPC016 in dermal papilla cells with aggregative behavior. (PMID: 16096800) Zhiqiang S. … Chunlan L. (Arch. Dermatol. Res. 2005) 3 4
  5. Interactions of pathological hallmark proteins: tubulin polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PMID: 21832049) OlA!h J. … OvA!di J. (J. Biol. Chem. 2011) 3

Products for TMA7 Gene

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat
  • QIAGEN qRT-PCR Assays for microRNAs that regulate TMA7
    • QuantiTect SYBR Green Assays in human,mouse,rat
    • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
    • QuantiFast Probe-based Assays in human,mouse,rat
    • Predesigned siRNA for gene silencing in human,mouse,rat for TMA7
    • Block miRNA regulation of TMA7 using miScript Target Protectors

    Sources for TMA7 Gene

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