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TM9SF4 Gene

protein-coding   GIFtS: 52
GCID: GC20P030697

Transmembrane 9 Superfamily Protein Member 4

  Search for TM9SF4
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Transmembrane 9 Superfamily Protein Member 41 2
dJ836N17.22
Dinucleotide Oxidase Disulfide Thiol Exchanger 3 Superfamily Member 42
Transmembrane 9 Superfamily Member 42
KIAA02553

External Ids:    HGNC: 307971   Entrez Gene: 97772   Ensembl: ENSG000001013377   UniProtKB: Q925443   

Export aliases for TM9SF4 gene to outside databases

Previous GC identifers: GC20P031395 GC20P031442 GC20P030161 GC20P030184 GC20P027486


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for TM9SF4 Gene:
TM9SF4 (transmembrane 9 superfamily protein member 4) is a protein-coding gene. An important paralog of this gene is TM9SF3.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000020.10  NT_011362.11  NC_018931.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the TM9SF4 gene promoter:
         COUP-TF1   TBP   GCNF   COUP   HNF-4alpha2   RelA   HNF-4alpha1   COUP-TF   GCNF-1   GCNF-2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidTM9SF4 promoter sequence
   Search Chromatin IP Primers for TM9SF4

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat TM9SF4


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 20q11.21   Ensembl cytogenetic band:  20q11.21   HGNC cytogenetic band: 20q11.21

TM9SF4 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TM9SF4 gene location

GeneLoc information about chromosome 20         GeneLoc Exon Structure

GeneLoc location for GC20P030697:  view genomic region     (about GC identifiers)

Start:
30,697,309 bp from pter      End:
30,755,061 bp from pter
Size:
57,753 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: TM9S4_HUMAN, Q92544 (See protein sequence)
Recommended Name: Transmembrane 9 superfamily member 4 precursor  
Size: 642 amino acids; 74519 Da
Sequence caution: Sequence=AAH21107.1; Type=Erroneous initiation; Sequence=BAA13385.2; Type=Erroneous initiation;
Secondary accessions: B0QYT7 Q9NUA3

Explore the universe of human proteins at neXtProt for TM9SF4: NX_Q92544

Explore proteomics data for TM9SF4 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys72
  • Modification sites at PhosphoSitePlus

  • See TM9SF4 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_055557.2  
    ENSEMBL proteins: 
     ENSP00000381104   ENSP00000413382   ENSP00000390314   ENSP00000217315   ENSP00000404755  

    TM9SF4 Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
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    OriGene Protein Over-expression Lysate for TM9SF4
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    Novus Biologicals TM9SF4 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for TM9SF4

     
    Search eBioscience for Proteins for TM9SF4 

    TM9SF4 Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
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    Novus Biologicals TM9SF4 Antibodies
    Abcam antibodies for TM9SF4
    Cloud-Clone Corp. Antibodies for TM9SF4
    ThermoFisher Antibodies for TM9SF4
    LSBio Antibodies in human, mouse, rat for TM9SF4

    TM9SF4 Assay Products:

    Browse Kits and Assays available from EMD Millipore
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    GenScript Custom Assay Services for TM9SF4
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for TM9SF4
    Cloud-Clone Corp. CLIAs for TM9SF4
    Search eBioscience for ELISAs for TM9SF4 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    1 InterPro protein domain:
     IPR004240 EMP70

    Graphical View of Domain Structure for InterPro Entry Q92544

    ProtoNet protein and cluster: Q92544

    1 Blocks protein domain: IPB004240 Nonaspanin (TM9SF)

    UniProtKB/Swiss-Prot: TM9S4_HUMAN, Q92544
    Similarity: Belongs to the nonaspanin (TM9SF) family


    Find genes that share domains with TM9SF4           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Phenotypes:
         1 GenomeRNAi human phenotype for TM9SF4:
     Synthetic lethal with c-Myc af 

         3 MGI mutant phenotypes (inferred from 2 alleles(MGI details for Tm9sf4):
     endocrine/exocrine gland  integument  skeleton 

    Find genes that share phenotypes with TM9SF4           About GenesLikeMe

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for TM9SF4
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for TM9SF4

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for TM9SF4
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for TM9SF4

    miRNA
    Products:
        
    miRTarBase miRNAs that target TM9SF4:
    hsa-mir-1226-3p (MIRT036460)

    Block miRNA regulation of human, mouse, rat TM9SF4 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate TM9SF4 (see all 46):
    hsa-miR-1914* hsa-miR-139-5p hsa-miR-200a hsa-miR-578 hsa-miR-877* hsa-miR-141 hsa-miR-3613-3p hsa-miR-3148
    SwitchGear 3'UTR luciferase reporter plasmidTM9SF4 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for TM9SF4
    Predesigned siRNA for gene silencing in human, mouse, rat TM9SF4

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for TM9SF4

    Clone
    Products:
         
    OriGene clones in human, mouse for TM9SF4 (see all 7)
    OriGene ORF clones in mouse, rat for TM9SF4
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: TM9SF4 (NM_014742)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TM9SF4
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TM9SF4

    Cell Line
    Products:
         
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    Browse ESI BIO Cell Lines and PureStem Progenitors for TM9SF4 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TM9SF4


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    TM9S4_HUMAN, Q92544: Membrane; Multi-pass membrane protein (Probable)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    plasma membrane3
    endosome1

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0016021integral component of membrane IEA--

    Find genes that share ontologies with TM9SF4           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for TM9SF4
    Interactions:

        Search GeneGlobe Interaction Network for TM9SF4

    STRING Interaction Network Preview (showing 5 interactants - click image to see 6)

    Selected Interacting proteins for TM9SF4 (Q925442, 3 ENSP000003811044) via UniProtKB, MINT, STRING, and/or I2D (see all 15)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    RAB5AP203392, 3, ENSP000002730474MINT-7307320 MINT-7307331 I2D: score=1 STRING: ENSP00000273047
    ARCN1P484443, ENSP000002640284I2D: score=4 STRING: ENSP00000264028
    UBCP0CG483, ENSP000003448184I2D: score=1 STRING: ENSP00000344818
    HSP90AA1P079003I2D: score=3 
    ATP13A1Q9HD203I2D: score=1 
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for TM9SF4 (TM9S4)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for TM9SF4 gene: 
    NM_014742.3  

    Unigene Cluster for TM9SF4:

    Transmembrane 9 superfamily protein member 4
    Hs.654665  [show with all ESTs]
    Unigene Representative Sequence: D87444
    7 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000398022(uc010ztr.1 uc002wxj.2 uc010zts.1) ENST00000442842
    ENST00000450829 ENST00000217315(uc002wxk.2) ENST00000417389 ENST00000495749
    ENST00000479591
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat TM9SF4 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate TM9SF4 (see all 46):
    hsa-miR-1914* hsa-miR-139-5p hsa-miR-200a hsa-miR-578 hsa-miR-877* hsa-miR-141 hsa-miR-3613-3p hsa-miR-3148
    SwitchGear 3'UTR luciferase reporter plasmidTM9SF4 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for TM9SF4
    Predesigned siRNA for gene silencing in human, mouse, rat TM9SF4
    Clone
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    OriGene clones in human, mouse for TM9SF4 (see all 7)
    OriGene ORF clones in mouse, rat for TM9SF4
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: TM9SF4 (NM_014742)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TM9SF4
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TM9SF4
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for TM9SF4
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat TM9SF4
      QuantiTect SYBR Green Assays in human, mouse, rat TM9SF4
      QuantiFast Probe-based Assays in human, mouse, rat TM9SF4

    Additional mRNA sequence: 

    AK124411.1 AK126534.1 AK294980.1 AK296500.1 AK302439.1 AK316293.1 BC005173.2 BC021107.1 
    BC022850.2 D87444.1 

    16 DOTS entries:

    DT.448936  DT.99942986  DT.100821109  DT.40264054  DT.100655010  DT.100821127  DT.92446720  DT.100821128 
    DT.40281764  DT.120808427  DT.120808532  DT.92409358  DT.92446714  DT.95125992  DT.100011944  DT.95361393 

    Selected AceView cDNA sequences (see all 354):

    CK902064 AI361016 AI922862 BG060060 CK430830 BP354795 CN479934 AA300794 
    CA487341 N42586 BM986755 BC021107 F11692 AI863909 CR611710 AA551238 
    BM844318 AL705045 AI421759 BQ941288 AA570059 BX642663 CN479978 BI522618 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    TM9SF4 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TCATCACAAA
    TM9SF4 Expression
    About this image


    TM9SF4 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     
     Eye (Sensory Organs)
             Retina
    TM9SF4 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    TM9SF4 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.654665
        Custom PCR Arrays for TM9SF4
    Primer
    Products:
    OriGene qSTAR qPCR primer pairs in human, mouse for TM9SF4
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat TM9SF4
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    QuantiFast Probe-based Assays in human, mouse, rat TM9SF4
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TM9SF4

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of eukaryotes.

    Orthologs for TM9SF4 gene from Selected species (see all 23)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Tm9sf41 , 5 transmembrane 9 superfamily protein member 41, 5 91.48(n)1
    96.88(a)1
      2 (75.41 cM)5
    992371  NM_133847.31  NP_598608.21 
     1531613035 
    chicken
    (Gallus gallus)
    Aves TM9SF41 transmembrane 9 superfamily protein member 4 81.38(n)
    91.89(a)
      419281  XM_417455.4  XP_417455.4 
    lizard
    (Anolis carolinensis)
    Reptilia TM9SF46
    transmembrane 9 superfamily protein member 4
    90(a)
    1 ↔ 1
    GL343505.1(422739-435278)
    African clawed frog
    (Xenopus laevis)
    Amphibia LOC3988642 hypothetical protein LOC398864 80.51(n)    BC060487.1 
    zebrafish
    (Danio rerio)
    Actinopterygii zgc662342 hypothetical protein MGC66234 76.93(n)   393482  BC055558.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta TM9SF41 TM9SF4 65.47(n)
    65.85(a)
      34778  NM_135825.3  NP_609669.1 
    worm
    (Caenorhabditis elegans)
    Secernentea ZK858.61 ZK858.6 58.22(n)
    58.61(a)
      172739  NM_001136332.1  NP_001129804.1 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes EMP70(YLR083C)4 Protein with a role in cellular adhesion, filamentous more   --   12(296094-294091) 850772  NP_013184.1 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons TMN71 TMN7 59.06(n)
    54.52(a)
      820587  NM_112228.2  NP_187991.1 
    rice
    (Oryza sativa)
    Liliopsida AK066545.12   -- 73.07(n)    AK066545.1 


    ENSEMBL Gene Tree for TM9SF4 (if available)
    TreeFam Gene Tree for TM9SF4 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for TM9SF4 gene
    TM9SF32  ENSG000002546922  ENSG000002595222  TM9SF22  TM9SF12  
    4 SIMAP similar genes for TM9SF4 using alignment to 3 protein entries:     TM9S4_HUMAN (see all proteins):
    TM9SF2    TM9SF3    TM9SF1    SMBP

    Find genes that share paralogs with TM9SF4           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for TM9SF4 (see all 1191)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 20 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1439939051,2
    --30695372(+) GCTTGA/GTGGCA 1 -- us2k10--------
    rs1882247161,2
    --30695531(+) AAAAAA/GAAGAG 1 -- us2k10--------
    rs1927962941,2
    --30695577(+) AAATGC/TGTTCT 1 -- us2k10--------
    rs1464145431,2
    --30695780(+) GGATCC/GAAGCT 1 -- us2k10--------
    rs739067381,2
    C,F--30695896(+) CAGGAT/CGGTTG 1 -- us2k12Minor allele frequency- C:0.05WA 120
    rs1834707111,2
    --30695920(+) AGTTAA/GTGGGT 1 -- us2k10--------
    rs732489651,2
    C--30695936(+) TTTCAA/GTGATC 1 -- us2k12Minor allele frequency- G:0.09WA 120
    rs1411306621,2
    --30695938(+) TCAATG/TATCTA 1 -- us2k10--------
    rs1884044901,2
    --30696015(+) TCCACA/GTGGTG 1 -- us2k10--------
    rs1448668111,2
    --30696344(+) ATCTCC/TTGAGG 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for TM9SF4 (30697309 - 30755061 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for TM9SF4:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv833954CNV Loss17160897
    nsv833953CNV Loss17160897

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing TM9SF4
    DNA2.0 Custom Variant and Variant Library Synthesis for TM9SF4

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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      --

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for TM9SF4 gene, integrated from 10 sources (see all 14):
    (articles sorted by number of sources associating them with TM9SF4)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Prediction of the coding sequences of unidentified human genes. VI. The coding sequences of 80 new genes (KIAA0201-KIAA0280) deduced by analysis of cDNA clones from cell line KG-1 and brain. (PubMed id 9039502)1, 2, 3 Nagase T.... Nomura N. (DNA Res. 1996)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    3. The DNA sequence and comparative analysis of human chromosome 20. (PubMed id 11780052)1, 2 Deloukas P....Rogers J. (Nature 2001)
    4. The human homologue of Dictyostelium discoideum phg1A is expressed by human metastatic melanoma cells. (PubMed id 19893578)1, 9 Lozupone F....Fais S. (EMBO Rep. 2009)
    5. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (Cell 2012)
    6. Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease. (PubMed id 23128233)1 Jostins L....Cho J.H. (Nature 2012)
    7. Systematic and quantitative assessment of the ubiquitin-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (Mol. Cell 2011)
    8. Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (amp 2011)
    9. A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (amp 2011)
    10. Ubiquitin-mediated proteolysis of HuR by heat shock. (PubMed id 19322201)1 Abdelmohsen K....Gorospe M. (EMBO J. 2009)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 9777 HGNC: 30797 AceView: TM9SF4 Ensembl:ENSG00000101337 euGenes: HUgn9777
    ECgene: TM9SF4 H-InvDB: TM9SF4

    (According to HUGE)
    About This Section

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    HUGE: KIAA0255

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

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    NameDescription
    PharmGKB entry for TM9SF4 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

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    Patent Information for TM9SF4 gene:
    Search GeneIP for patents involving TM9SF4

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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