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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

TM9SF2 Gene

protein-coding   GIFtS: 55
GCID: GC13P100153

Transmembrane 9 Superfamily Member 2

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Transmembrane 9 Superfamily Member 21 2
76 KDa Membrane Protein2
P762
Transmembrane Protein 9 Superfamily Member 22
p763

External Ids:    HGNC: 118651   Entrez Gene: 93752   Ensembl: ENSG000001253047   OMIM: 6046785   UniProtKB: Q998053   

Export aliases for TM9SF2 gene to outside databases

Previous GC identifers: GC13P098513 GC13P094540 GC13P098990 GC13P097851 GC13P098951 GC13P080748


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for TM9SF2 Gene:
This gene encodes a member of the transmembrane 9 superfamily. The encoded 76 kDa protein localizes to early
endosomes in human cells. The encoded protein possesses a conserved and highly hydrophobic C-terminal domain
which contains nine transmembrane domains. The protein may play a role in small molecule transport or act as an
ion channel. A pseudogene associated with this gene is located on the X chromosome. (provided by RefSeq, Oct
2012)

GeneCards Summary for TM9SF2 Gene: 
TM9SF2 (transmembrane 9 superfamily member 2) is a protein-coding gene. Diseases associated with TM9SF2 include leptospirosis, and thyroid cancer. An important paralog of this gene is TM9SF3.

UniProtKB/Swiss-Prot: TM9S2_HUMAN, Q99805
Function: In the intracellular compartments, may function as a channel or small molecule transporter

Gene Wiki entry for TM9SF2 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000013.10  NC_018924.2  NT_009952.14  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the TM9SF2 gene promoter:
         STAT5B   STAT1   Nkx2-2   STAT4   STAT1beta   STAT6   STAT5A   STAT1alpha   STAT2   STAT3   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidTM9SF2 promoter sequence
   Search SABiosciences Chromatin IP Primers for TM9SF2

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TM9SF2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 13q32.3   Ensembl cytogenetic band:  13q32.3   HGNC cytogenetic band: 13q32.2

TM9SF2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TM9SF2 gene location

GeneLoc information about chromosome 13         GeneLoc Exon Structure

GeneLoc location for GC13P100153:  view genomic region     (about GC identifiers)

Start:
100,153,671 bp from pter      End:
100,216,260 bp from pter
Size:
62,590 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: TM9S2_HUMAN, Q99805 (See protein sequence)
Recommended Name: Transmembrane 9 superfamily member 2 precursor  
Size: 663 amino acids; 75776 Da
Subcellular location: Endosome membrane; Multi-pass membrane protein (Probable)
Secondary accessions: A8K399 Q2TAY5

Explore the universe of human proteins at neXtProt for TM9SF2: NX_Q99805

Explore proteomics data for TM9SF2 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q99805

  • TM9SF2 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    TM9SF2 Protein Expression
    REFSEQ proteins: NP_004791.1  
    ENSEMBL proteins: 
     ENSP00000365567  

    Human Recombinant Protein Products for TM9SF2: 
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    Novus Biologicals TM9SF2 Protein
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for TM9SF2 

    Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005768endosome TAS9729438
    GO:0005887integral to plasma membrane TAS9729438
    GO:0010008endosome membrane IEA--
    GO:0016021integral to membrane ----

    TM9SF2 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    1 InterPro protein domain:
     IPR004240 EMP70

    Graphical View of Domain Structure for InterPro Entry Q99805

    ProtoNet protein and cluster: Q99805

    1 Blocks protein domain: IPB004240 Nonaspanin (TM9SF)

    UniProtKB/Swiss-Prot: TM9S2_HUMAN, Q99805
    Similarity: Belongs to the nonaspanin (TM9SF) family


    TM9SF2 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: TM9S2_HUMAN, Q99805
    Function: In the intracellular compartments, may function as a channel or small molecule transporter

    Phenotypes:
         1 GenomeRNAi human phenotype for TM9SF2:

     Decreased p24 protein expressi 

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for TM9SF2 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for TM9SF2

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    1 QIAGEN miScript miRNA Assays for microRNA that regulate TM9SF2:
    hsa-miR-105
    SwitchGear 3'UTR luciferase reporter plasmidTM9SF2 3' UTR sequence
    Inhib. RNA
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                         Customized lentivirus expression plasmids for stable overexpression of TM9SF2 

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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TM9SF2


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for TM9SF2

    STRING Interaction Network Preview (showing 5 interactants - click image to see 6)

    5/6 Interacting proteins for TM9SF2 (Q998052, 3 ENSP000003655674) via UniProtKB, MINT, STRING, and/or I2D (see all 6)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    SMAD4Q134852, 3, ENSP000003415514MINT-61975 I2D: score=3 STRING: ENSP00000341551
    RAB9AP511513, ENSP000004201274I2D: score=2 STRING: ENSP00000420127
    UNC93B1Q9H1C43, ENSP000002274714I2D: score=1 STRING: ENSP00000227471
    UBCENSP000003448184STRING: ENSP00000344818
    TM9SF4ENSP000003811044STRING: ENSP00000381104
    About this table

    Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006810transport TAS9729438

    TM9SF2 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    TM9SF2 for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for TM9SF2 (TM9S2)

    2 Novoseek inferred chemical compound relationships for TM9SF2 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    mannose 6-phosphate 61.4 2 17105447 (1), 9729438 (1)
    tyrosine 27.9 2 7678053 (1)

    Search CenterWatch for drugs/clinical trials and news about TM9SF2 / TM9S2

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for TM9SF2 gene: 
    NM_004800.2  

    Unigene Cluster for TM9SF2:

    Transmembrane 9 superfamily member 2
    Hs.607896  [show with all ESTs]
    Unigene Representative Sequence: NM_004800
    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000376387(uc001voj.1 uc010afz.1) ENST00000463709 ENST00000466555

    miRNA
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    1 QIAGEN miScript miRNA Assays for microRNA that regulate TM9SF2:
    hsa-miR-105
    SwitchGear 3'UTR luciferase reporter plasmidTM9SF2 3' UTR sequence
    Inhib. RNA
    Products:
         
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TM9SF2
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TM9SF2

    Additional mRNA sequence: 

    AK093507.1 AK129798.1 AK225800.1 AK290514.1 AK315210.1 BC110656.1 BC130293.1 L13803.1 
    U81006.1 

    24/25 DOTS entries (see all 25):

    DT.95112729  DT.317194  DT.95372525  DT.120765865  DT.40310184  DT.100824973  DT.120765841  DT.95372531 
    DT.120765845  DT.120765888  DT.86840568  DT.95303455  DT.100771316  DT.120765851  DT.120765839  DT.40314711 
    DT.92005039  DT.120765853  DT.95164546  DT.95372529  DT.97817484  DT.120705076  DT.92005498  DT.95086936 

    24/499 AceView cDNA sequences (see all 499):

    BP358967 BI258263 BQ436012 AI567280 BQ774329 AA364133 L13803 CA424084 
    AV652362 BF970014 AW028981 AA479252 BM354119 AA318629 AU120958 CD358425 
    BP333869 BX956364 BP365323 CK299887 BG779837 BX956407 AI248922 BU753639 

    GeneLoc Exon Structure

    4 Alternative Splicing Database (ASD) splice patterns (SP) for TM9SF2    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13a · 13b ^ 14a · 14b ^ 15 ^ 16a · 16b ^ 17
    SP1:              -                                                                 -                             -               
    SP2:                                                                                                                              
    SP3:                                                                                                                              
    SP4:                                                                                                                              


    ECgene alternative splicing isoforms for TM9SF2

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TM9SF2 expression in normal human tissues (normalized intensities)      TM9SF2 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GTATTGGCCT
    TM9SF2 Expression
    About this image


    TM9SF2 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/22 selected tissues (see all 22) fully expand
     
     Testis (Reproductive System)    fully expand to see all 4 entries
             Leydig Cells Testis Interstitium
             seminal vesicle ; glandular cells   
     
     Brain (Nervous System)    fully expand to see all 4 entries
             Cerebral Cortex
     
     Blood (Hematopoietic System)    fully expand to see all 2 entries
             Hematopoietic Stem Cells Hematopoietic Bone Marrow
             lung ; macrophages   
     
     Pancreas (Endocrine System)    fully expand to see all 2 entries
             Islets of Langerhans
             pancreas ; exocrine glandular cells   
     
     Colon (Gastrointestinal Tract)    fully expand to see all 2 entries
             rectum ; glandular cells   

    See TM9SF2 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for TM9SF2

    SOURCE GeneReport for Unigene cluster: Hs.607896

    UniProtKB/Swiss-Prot: TM9S2_HUMAN, Q99805
    Tissue specificity: Ubiquitously expressed. Especially abundant in pancreas, highly expressed in kidney, lower
    levels in heart, brain, skeletal muscle and placenta. Lowest expression in lung and liver

        SABiosciences Custom PCR Arrays for TM9SF2
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    In Situ
    Assay Products:
     

     
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for TM9SF2 gene from 10/24 species (see all 24)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Tm9sf21 , 5 transmembrane 9 superfamily member 21, 5 90.13(n)1
    95.77(a)1
      14 (65.86 cM)5
    680591  NM_080556.31  NP_542123.31 
     1221070385 
    chicken
    (Gallus gallus)
    Aves TM9SF21 transmembrane 9 superfamily member 2 81.28(n)
    91.98(a)
      418777  XM_416972.3  XP_416972.1 
    lizard
    (Anolis carolinensis)
    Reptilia TM9SF26
    Uncharacterized protein
    89(a)
    1 ↔ 1
    3(98895605-98929991)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.162762 Xenopus laevis cDNA clone IMAGE4724777, partial cds 81.43(n)    BC057725.1 
    zebrafish
    (Danio rerio)
    Actinopterygii wufi20b052 Danio rerio mRNA similar to transmembrane 9 superfamily more 75.1(n)    BC049137.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG93183   -- 68(a)   38E3   --
    worm
    (Caenorhabditis elegans)
    Secernentea F08F1.73
    tag-1231
    Protein TAG-1231 62(a)3
    61.81(n)1
    63.48(a)1
      X(8454354-8457295)3
    1810961  NM_077028.41  NP_509429.11 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes TMN21 Tmn2p 50.55(n)
    38.74(a)
      851685   NP_010392.1 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons TMN71 protein transmembrane nine 7 55.7(n)
    51.79(a)
      820587  NM_112228.2  NP_187991.1 
    rice
    (Oryza sativa)
    Liliopsida Os09g05578001 hypothetical protein 56.53(n)
    51.78(a)
      4347829  NM_001070441.1  NP_001063906.1 


    ENSEMBL Gene Tree for TM9SF2 (if available)
    TreeFam Gene Tree for TM9SF2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for TM9SF2 gene
    TM9SF32  ENSG000002546922  ENSG000002595222  TM9SF42  TM9SF12  
    4 SIMAP similar genes for TM9SF2 using alignment to 1 protein entry:     TM9S2_HUMAN:
    TM9SF4    SMBP    TM9SF3    TM9SF1

    TM9SF2 for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for TM9SF2
    PGOHUM00000242042


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/1345 SNPs in TM9SF2 are shown (see all 1345)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 13 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs741122521,2
    C,F--100151754(+) TAGGTT/CCTTCT 1 -- us2k12Minor allele frequency- C:0.08WA 120
    rs73185491,2
    C,F,A,H--100151812(+) aaaacT/Agggag 1 -- us2k17Minor allele frequency- A:0.07NS EA WA CSA 540
    rs1448706201,2
    C--100151862(+) GTCAA-/GTTT  
     TTTTTTT
    GTTTT
    1 -- us2k10--------
    rs118423881,2
    C,A,H--100151873(+) TTTTTT/GTTTTT 1 -- us2k12Minor allele frequency- G:0.00NA CSA 3
    rs1421240891,2
    C--100151873(+) TTTTT-/GTTTTT 1 -- us2k10--------
    rs714334401,2
    C--100151881(+) TTTTTG/TTTTTT 1 -- us2k12Minor allele frequency- T:0.25NA 4
    rs711184831,2
    C--100151884(-) AAAAA-/AAAAAA 1 -- us2k11Minor allele frequency- A:0.00NA 2
    rs73187151,2
    C,A--100151885(+) tttttG/Tttttt 1 -- us2k1 trp30--------
    rs1389491721,2
    C--100151944(+) ATCTCA/GGCTTA 1 -- us2k10--------
    rs342822551,2
    C--100151964(+) CCGCC-/TCCCGG 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for TM9SF2 (100153671 - 100216260 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for TM9SF2:    About this table     
    Variant IDTypeSubtypePubMed ID
    esv34003CNV Loss18971310
    nsv510934CNV Complex20534489

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 604678    OMIM disorders: --

    5 diseases for TM9SF2:    About MalaCards
    leptospirosis    thyroid cancer    hodgkin's lymphoma    thyroiditis
    breast cancer


    TM9SF2 for disorders           About GeneDecksing

    Genetic Association Database (GAD): TM9SF2
    Human Genome Epidemiology (HuGE) Navigator: TM9SF2 (2 documents)

    Export disorders for TM9SF2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for TM9SF2 gene, integrated from 9 sources (see all 30):
    (articles sorted by number of sources associating them with TM9SF2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Characterization of a 76 kDa endosomal, multispanning membrane protein that is highly conserved throughout evolution. (PubMed id 9729438)1, 2, 3, 9 Schimmoeller F.... Pfeffer S.R. (1998)
    2. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (2010)
    3. The DNA sequence and analysis of human chromosome 13. (PubMed id 15057823)1, 2 Dunham A.... Ross M.T. (2004)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    6. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
    7. Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population. (PubMed id 23251661)1 Comuzzie A.G....Butte N.F. (2012)
    8. Mapping a dynamic innate immunity protein interaction network regulating type I interferon production. (PubMed id 21903422)1 Li S....Dorf M.E. (2011)
    9. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
    10. Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 9375 HGNC: 11865 AceView: TM9SF2 Ensembl:ENSG00000125304 euGenes: HUgn9375
    ECgene: TM9SF2 H-InvDB: TM9SF2

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for TM9SF2 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for TM9SF2 gene:
    Search GeneIP for patents involving TM9SF2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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