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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

TM4SF4 Gene

protein-coding   GIFtS: 48
GCID: GC03P149191

transmembrane 4 L six family member 4

(Previous name: transmembrane 4 superfamily member 4 )
 Explore 2 diseases affiliated with
TM4SF4 via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for TM4SF4    

Aliases
for TM4SF4 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Transmembrane 4 L Six Family Member 41 2     Intestine And Liver Tetraspan Membrane Protein2 3
ILTMP2 3 5     Intestinal And Liver (Il) Tetraspan Membrane Protein2
Il-TMP1     Transmembrane 4 L6 Family Member 42
Transmembrane 4 Superfamily Member 41 2     IL-TMP3

External Ids:    HGNC: 118561   Entrez Gene: 71042   Ensembl: ENSG000001699037   OMIM: 6065675   UniProtKB: P482303   

Export aliases for TM4SF4 gene to outside databases

Previous GC identifers: GC03P146120 GC03P150076 GC03P150473 GC03P150512 GC03P150674 GC03P146564


Summaries
for TM4SF4 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for TM4SF4:
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family.
Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains.
The proteins mediate signal transduction events that play a role in the regulation of cell development, activation,
growth and motility. This encoded protein is a cell surface glycoprotein that can regulate cell
proliferation.(provided by RefSeq, Mar 2011)

UniProtKB/Swiss-Prot: T4S4_HUMAN, P48230
Function: Regulates the adhesive and proliferative status of intestinal epithelial cells. Can mediate density-dependent
cell proliferation




Genomic Views
for TM4SF4 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000003.11  NC_018914.1  NT_005612.16  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the TM4SF4 gene promoter:
         C/EBPbeta   AML1a   FOXO3   Evi-1   E47   FOXO3b   Nkx6-1   HFH-1   FOXO3a   ATF6   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: TM4SF4 promoter sequence
   Search SABiosciences Chromatin IP Primers for TM4SF4

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TM4SF4


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 3q25   Ensembl cytogenetic band:  3q25.1   HGNC cytogenetic band: 3q25

TM4SF4 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TM4SF4 gene location

GeneLoc information about chromosome 3         GeneLoc Exon Structure

GeneLoc location for GC03P149191:  view genomic region     (about GC identifiers)

Start:
 149,191,761 bp from pter      End:
 149,221,068 bp from pter
Size:
 29,308 bases      Orientation:
 plus strand

Proteins
for TM4SF4 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: T4S4_HUMAN, P48230 (See protein sequence)
Recommended Name: Transmembrane 4 L6 family member 4  
Size: 202 amino acids; 21396 Da
Subcellular location: Membrane; Multi-pass membrane protein
Secondary accessions: B2RDA4

Explore the universe of human proteins at neXtProt for TM4SF4: NX_P48230

Post-translational modifications:

  • N-glycosylated. Glycosylation is required for the growth inhibitory effect1
  • View neXtProt modification sites for NX_P48230

    • TM4SF4 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_004608.1  
    ENSEMBL proteins: 
     ENSP00000305852   ENSP00000419367  

    Human Recombinant Protein Products: 
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    Novus Biologicals TM4SF4 Protein
    Novus Biologicals TM4SF4 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins
    Uscn Proteins for TM4SF4

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0016021integral to membrane IEA--


    TM4SF4 for ontologies           About GeneDecksing



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    Uscn ELISAs and CLIAs for TM4SF4

    Protein Domains /
    Families
    for TM4SF4 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    TM4SF4 for domains           About GeneDecksing

    1 InterPro domain/family:
     IPR008661 L6_membrane

    Graphical View of Domain Structure for InterPro Entry P48230

    ProtoNet protein and cluster: P48230

    1 Blocks protein family: IPB008661 L6 membrane

    UniProtKB/Swiss-Prot: T4S4_HUMAN, P48230
    Similarity: Belongs to the L6 tetraspanin family


    Function
    for TM4SF4 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: T4S4_HUMAN, P48230
    Function: Regulates the adhesive and proliferative status of intestinal epithelial cells. Can mediate density-dependent
    cell proliferation

    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat TM4SF4
    4 QIAGEN miScript miRNA Assays for microRNAs that regulate TM4SF4:
    hsa-miR-520d-5p hsa-miR-3674 hsa-miR-524-5p hsa-miR-664
    SwitchGear 3'UTR luciferase reporter plasmid: TM4SF4 3' UTR sequence
    Inhib. RNA
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    Gene Editing
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    Clone
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    OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TM4SF4 (see all 3)
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    Cell Line
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    Search LifeMap BioReagents cell lines for TM4SF4

    In Situ Assay
    Products:       
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TM4SF4


    Pathways & Interactions
    for TM4SF4 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for TM4SF4

    STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

    2 Interacting proteins for TM4SF4 (P482303 ENSP000003058524) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CREB3O438893I2D: score=1 
    SIRT1ENSP000002120154STRING: ENSP00000212015
    About this table

    Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0042246tissue regeneration IEA--


    TM4SF4 for ontologies           About GeneDecksing



    Drugs & Compounds
    for TM4SF4 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for TM4SF4
    Search CenterWatch for drugs/clinical trials and news about TM4SF4 / T4S4 

    Transcripts
    for TM4SF4 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for TM4SF4 gene: 
    NM_004617.3  

    Unigene Cluster for TM4SF4:

    Transmembrane 4 L six family member 4
    Hs.133527  [show with all ESTs]
    Unigene Representative Sequence: AK055577
    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000305354(uc003exd.2) ENST00000465758 ENST00000463068

    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat TM4SF4
    4 QIAGEN miScript miRNA Assays for microRNAs that regulate TM4SF4:
    hsa-miR-520d-5p hsa-miR-3674 hsa-miR-524-5p hsa-miR-664
    SwitchGear 3'UTR luciferase reporter plasmid: TM4SF4 3' UTR sequence
    Inhib. RNA
    Products:             		Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for TM4SF4 (see all 7)
    OriGene shRNA RFP: TM4SF4
    OriGene siRNA: TM4SF4
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TM4SF4
    Clone
    Products:             		 OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TM4SF4 (see all 3)
    OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TM4SF4 (see all 2)
    OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
    GenScript: all cDNA clones in your preferred vector: TM4SF4 (NM_004617)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TM4SF4
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TM4SF4 
    Primer
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TM4SF4
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TM4SF4

    Additional cDNA sequence: 

    AK055577.1 AK315464.1 BC001386.2 BT007430.1 U31449.1 

    7 DOTS entries:

    DT.456083  DT.92432504  DT.95272341  DT.100783606  DT.100029904  DT.92432501  DT.95272340 

    24/198 AceView cDNA sequences (see all 198):

    AI572072 BQ287802 AA452917 BX423709 U31449 CR624110 AK055577 NM_004617 
    T80802 BM825250 CA867064 AW518986 BM310834 AI566443 BE872624 BC001386 
    AW013983 AI584060 BG656336 AW338459 CA943651 BI253205 BM264034 AW339205 

    GeneLoc Exon Structure


    Expression
    for TM4SF4 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TM4SF4 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: GCTAGGGTTC

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    TM4SF4 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    1 LifeMap In Vivo Development Anatomical Compartment/Cell 
    Tissue Anatomical Compartment CellCategory (developmental path)
    PancreasVentral Pancreatic BudEndocrine Progenitor CellsPancreas
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization

    See TM4SF4 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for TM4SF4

    SOURCE GeneReport for Unigene cluster: Hs.133527

    UniProtKB/Swiss-Prot: T4S4_HUMAN, P48230
    Tissue specificity: Jejunum and liver

        SABiosciences Custom PCR Arrays for TM4SF4
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    In Situ
    Assay Products:     
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TM4SF4

    Orthologs
    for TM4SF4 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of chordates.

    Orthologs for TM4SF4 gene from 4/12 species (see all 12)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    chicken
    (Gallus gallus)    		 Aves TM4SF41 transmembrane 4 L six family member 4 69.65(n)
    72.64(a)    		   771806  XM_001234022.2  XP_001234023.1 
    lizard
    (Anolis carolinensis)    		 Reptilia TM4SF46
    		 --
    		 68(a)
    		 1 ↔ 1
    		 3(18960152-18967889)
    African clawed frog
    (Xenopus laevis)    		 Amphibia tm4sf4-prov2 transmembrane 4 superfamily member 4 77.52(n)    BC054239.1 
    zebrafish
    (Danio rerio)    		 Actinopterygii Dr.35632 Transcribed sequence with weak similarity to protein more 77.27(n)    CD015290.1 


    ENSEMBL Gene Tree for TM4SF4 (if available)
    TreeFam Gene Tree for TM4SF4 (if available) 

    Paralogs
    for TM4SF4 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for TM4SF4 gene
    TM4SF52  TM4SF192  TM4SF182  TM4SF12  
    4 SIMAP similar genes for TM4SF4 using alignment to 2 protein entries:     T4S4_HUMAN (see all proteins):
    TM4SF1    TM4SF5    TM4SF18    TM4SF19

    TM4SF4 for paralogs           About GeneDecksing



    Genomic Variants
    for TM4SF4 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/663 NCBI SNPs in TM4SF4 are shown (see all 663)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 3 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs799481011,2
    		F,--149190447(+) GTGTTG/AGAAAA 1 -- us2k12Minor allele frequency- A:0.07NA EA 240
    rs767806731,2
    		--149190449(+) GTTGGA/GAAACA 1 -- us2k13Minor allele frequency- G:0.04CSA WA EA 240
    rs1412232271,2
    		--149190493(+) TTCTGG/TTGGAA 1 -- us2k10--------
    rs1890064581,2
    		--149190538(+) TCTGTA/GTATCC 1 -- us2k10--------
    rs1163588171,2
    		F,--149190619(+) GAAGGG/ATCTCC 1 -- us2k11Minor allele frequency- A:0.02NA 120
    rs769920481,2
    		F,--149190625(+) TCTCCT/CACTGT 1 -- us2k12Minor allele frequency- C:0.07NA EA 240
    rs1507395941,2
    		--149190637(+) TGCATA/TTACCT 1 -- us2k10--------
    rs1808014401,2
    		--149190706(+) TTTTCA/TAAAAG 1 -- us2k10--------
    rs753257321,2
    		F,--149190713(+) AAAGGA/GAAATC 1 -- us2k11Minor allele frequency- G:0.03NA 120
    rs1852491021,2
    		--149190722(+) TCTATA/GAGAGA 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for TM4SF4 (149191761 - 149221068 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 1 variation for TM4SF4
         1 CNV: 23277

    SABiosciences Cancer Mutation PCR Assays
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    Disorders / Diseases
    for TM4SF4 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    TM4SF4 for disorders           About GeneDecksing

    OMIM gene information: 606567    OMIM disorders: --

    2 diseases for TM4SF4:    About MalaCards
    polycystic ovary syndrome    burkitt's lymphoma


    Export disorders for TM4SF4 gene to outside databases

    Publications
    for TM4SF4 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for TM4SF4 gene, integrated from 9 sources (see all 12):
    (articles sorted by number of sources associating them with TM4SF4)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. A tetraspan membrane glycoprotein produced in the human intestinal epithelium and liver that can regulate cell density-dependent proliferation. (PubMed id 7665614)1, 2, 3 Wice B.M. and Gordon J.I. (1995)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    4. Overexpression of S100B, TM4SF4, and OLFM4 genes is co rrelated with liver metastasis in Taiwanese colorectal cancer patients. (PubMed id 22011044)1 Huang M.Y....Lin S.R. (2012)
    5. Functional dissection of lysine deacetylases reveals t hat HDAC1 and p300 regulate AMPK. (PubMed id 22318606)1 Lin Y.Y....Boeke J.D. (2012)
    6. Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry. (PubMed id 19159218)2 Chen R.... Zou H. (2009)
    7. Microarray evaluation of endometrial receptivity in Chinese women with polycystic ovary syndrome. (PubMed id 18765015)1 Qiao J....Zhang X. (2008)
    8. Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions. (PubMed id 15342556)1 Suzuki Y.... Sugano S. (2004)
    9. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
    10. Complexes of tetraspanins with integrins: more than meets the eye. (PubMed id 11739647)1 Berditchevski F. (2001)

    External Searches for TM4SF4 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  
      Query String
    		PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    Genome Databases showing TM4SF4 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 7104 HGNC: 11856 AceView: TM4SF4 Ensembl:ENSG00000169903 euGenes: HUgn7104
    ECgene: TM4SF4 H-InvDB: TM4SF4

    Other Databases showing TM4SF4 gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing TM4SF4 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for TM4SF4 Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for TM4SF4 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for TM4SF4 gene:
    Search GeneIP for patents involving TM4SF4

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    Products
    for TM4SF4 gene

    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences),
    In Situ Hybridization Assays from
    Advanced Cell Diagnostics
    About This Section

     
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     Novus Tissue Slides
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     TM4SF4 Proteins, Antibodies, CLIAs, and ELISAs
     Search LifeMap BioReagents cell lines for TM4SF4
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TM4SF4
     SwitchGear 3'UTR luciferase reporter plasmids for TM4SF4
     SwitchGear Promoter luciferase reporter plasmids for TM4SF4
     ThermoFisher Antibodies for TM4SF4
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TM4SF4
           
    GeneCards Homepage - Last full update: 18 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013

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