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Aliases for TM4SF19-TCTEX1D2 Gene

Subcategory (RNA class) for TM4SF19-TCTEX1D2 Gene


Quality Score for this RNA gene is


Aliases for TM4SF19-TCTEX1D2 Gene

  • TM4SF19-TCTEX1D2 Readthrough (NMD Candidate) 2 3 5

External Ids for TM4SF19-TCTEX1D2 Gene

Previous GeneCards Identifiers for TM4SF19-TCTEX1D2 Gene

  • GC03U901733
  • GC03M196045
  • GC03M196048

Summaries for TM4SF19-TCTEX1D2 Gene

Entrez Gene Summary for TM4SF19-TCTEX1D2 Gene

  • This locus represents naturally occurring read-through transcription between the neighboring transmembrane 4 L six family member 19 (TM4SF19) and Tctex1 domain containing 2 (TCTEX1D2) genes on chromosome 3. The read-through transcript is a candidate for nonsense-mediated mRNA decay (NMD), and is thus not expected to produce a protein product. [provided by RefSeq, Mar 2011]

GeneCards Summary for TM4SF19-TCTEX1D2 Gene

TM4SF19-TCTEX1D2 (TM4SF19-TCTEX1D2 Readthrough (NMD Candidate)) is an RNA Gene, and is affiliated with the ncRNA class. An important paralog of this gene is TM4SF19.

Additional gene information for TM4SF19-TCTEX1D2 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TM4SF19-TCTEX1D2 Gene

Genomics for TM4SF19-TCTEX1D2 Gene

Regulatory Elements for TM4SF19-TCTEX1D2 Gene

Enhancers for TM4SF19-TCTEX1D2 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH03H196335 1.2 Ensembl ENCODE dbSUPER 0.7 +2.0 2020 1.2 HDAC1 BRD4 PKNOX1 ATF1 BACH1 POLR2A ZNF584 ATF7 CREM ZNF639 TM4SF19 TM4SF19-AS1 TM4SF19-TCTEX1D2
GH03H196334 0.4 Ensembl 0.7 +3.7 3720 0.2 MAZ TM4SF19-TCTEX1D2 TM4SF19-AS1
GH03H196320 0.4 FANTOM5 0.4 +17.5 17544 0.3 POLR2A TM4SF19 TM4SF19-AS1 TM4SF19-TCTEX1D2
GH03H196321 0.4 ENCODE 0.4 +17.9 17924 0.4 POLR2A ZNF341 SLC51A TM4SF19-AS1 TM4SF19-TCTEX1D2
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around TM4SF19-TCTEX1D2 on UCSC Golden Path with GeneCards custom track

Genomic Locations for TM4SF19-TCTEX1D2 Gene

Genomic Locations for TM4SF19-TCTEX1D2 Gene
22,339 bases
Minus strand

Genomic View for TM4SF19-TCTEX1D2 Gene

Genes around TM4SF19-TCTEX1D2 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TM4SF19-TCTEX1D2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TM4SF19-TCTEX1D2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TM4SF19-TCTEX1D2 Gene

Proteins for TM4SF19-TCTEX1D2 Gene

Post-translational modifications for TM4SF19-TCTEX1D2 Gene

No Post-translational modifications

Other Protein References for TM4SF19-TCTEX1D2 Gene

ENSEMBL proteins:

No data available for DME Specific Peptides for TM4SF19-TCTEX1D2 Gene

Domains & Families for TM4SF19-TCTEX1D2 Gene

Graphical View of Domain Structure for InterPro Entry

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for TM4SF19-TCTEX1D2 Gene

Function for TM4SF19-TCTEX1D2 Gene

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for TM4SF19-TCTEX1D2 Gene

Localization for TM4SF19-TCTEX1D2 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for TM4SF19-TCTEX1D2 Gene

Pathways & Interactions for TM4SF19-TCTEX1D2 Gene

SuperPathways for TM4SF19-TCTEX1D2 Gene

No Data Available

Interacting Proteins for TM4SF19-TCTEX1D2 Gene

Gene Ontology (GO) - Biological Process for TM4SF19-TCTEX1D2 Gene


No data available for Pathways by source and SIGNOR curated interactions for TM4SF19-TCTEX1D2 Gene

Drugs & Compounds for TM4SF19-TCTEX1D2 Gene

No Compound Related Data Available

Transcripts for TM4SF19-TCTEX1D2 Gene

mRNA/cDNA for TM4SF19-TCTEX1D2 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for TM4SF19-TCTEX1D2 Gene

No ASD Table

Relevant External Links for TM4SF19-TCTEX1D2 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for TM4SF19-TCTEX1D2 Gene

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for TM4SF19-TCTEX1D2 Gene

Orthologs for TM4SF19-TCTEX1D2 Gene

This gene was present in the common ancestor of chordates.

Orthologs for TM4SF19-TCTEX1D2 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia -- 34
  • 99 (a)
(Bos Taurus)
Mammalia -- 34
  • 83 (a)
(Canis familiaris)
Mammalia -- 34
  • 83 (a)
(Mus musculus)
Mammalia Tm4sf19 34
  • 79 (a)
(Monodelphis domestica)
Mammalia -- 34
  • 65 (a)
(Ornithorhynchus anatinus)
Mammalia -- 34
  • 44 (a)
(Gallus gallus)
Aves TM4SF19 34
  • 36 (a)
(Anolis carolinensis)
Reptilia -- 34
  • 45 (a)
(Danio rerio)
Actinopterygii si:ch211-137i24.10 34
  • 36 (a)
Species where no ortholog for TM4SF19-TCTEX1D2 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for TM4SF19-TCTEX1D2 Gene

Gene Tree for TM4SF19-TCTEX1D2 (if available)
Gene Tree for TM4SF19-TCTEX1D2 (if available)

Paralogs for TM4SF19-TCTEX1D2 Gene

Paralogs for TM4SF19-TCTEX1D2 Gene

genes like me logo Genes that share paralogs with TM4SF19-TCTEX1D2: view

Variants for TM4SF19-TCTEX1D2 Gene

Sequence variations from dbSNP and Humsavar for TM4SF19-TCTEX1D2 Gene

SNP ID Clin Chr 03 pos Sequence Context AA Info Type
rs147419407 Uncertain significance 196,327,503(+) CCCAG(C/G)AGCAA nc-transcript-variant, reference, missense
rs1000008545 -- 196,331,431(+) GTCTG(C/T)CTCCC intron-variant
rs1000136578 -- 196,338,286(+) AATCA(C/G)AATGG nc-transcript-variant, utr-variant-5-prime
rs1000234732 -- 196,319,988(+) TGGCA(C/G/T)GTGCC intron-variant, upstream-variant-2KB
rs1000357265 -- 196,318,352(+) GACGC(-/G)CGACA intron-variant, nc-transcript-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for TM4SF19-TCTEX1D2 Gene

Variant ID Type Subtype PubMed ID
nsv997797 CNV gain 25217958
nsv950311 CNV deletion 24416366
nsv593085 CNV gain+loss 21841781
nsv593084 CNV gain 21841781
nsv593083 CNV gain 21841781
nsv593082 CNV gain+loss 21841781
nsv593079 CNV loss 21841781
nsv593071 CNV gain 21841781
nsv513108 CNV loss 21212237
nsv509878 OTHER sequence alteration 20534489
nsv4183 CNV deletion 18451855
nsv1136374 CNV deletion 24896259
nsv1135926 CNV deletion 24896259
nsv1074120 CNV deletion 25765185
nsv1009811 CNV gain 25217958
esv4542 CNV loss 18987735
esv3599281 CNV loss 21293372
esv3599280 CNV loss 21293372
esv3563177 CNV deletion 23714750
esv3407163 CNV duplication 20981092
esv3389071 CNV duplication 20981092
esv2759213 CNV gain+loss 17122850
esv2677485 CNV deletion 23128226
esv26108 CNV gain 19812545
esv2370851 CNV deletion 18987734
esv1444129 CNV insertion 17803354
dgv8849n54 CNV gain 21841781

Relevant External Links for TM4SF19-TCTEX1D2 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for TM4SF19-TCTEX1D2 Gene

Disorders for TM4SF19-TCTEX1D2 Gene

Relevant External Links for TM4SF19-TCTEX1D2

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for TM4SF19-TCTEX1D2 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for TM4SF19-TCTEX1D2 Gene

Publications for TM4SF19-TCTEX1D2 Gene

  1. Expression of conjoined genes: another mechanism for gene regulation in eukaryotes. (PMID: 20967262) Prakash T … Taylor TD (PloS one 2010) 3 60
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 3 60

Products for TM4SF19-TCTEX1D2 Gene

Sources for TM4SF19-TCTEX1D2 Gene

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