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TM4SF1 Gene

protein-coding   GIFtS: 54
GCID: GC03M149086

Transmembrane 4 L Six Family Member 1

(Previous name: transmembrane 4 superfamily member 1)
(Previous symbol: M3S1)
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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Transmembrane 4 L Six Family Member 11 2     Tumor-Associated Antigen L62 3
M3S11 2 3 5     H-L62
TAAL62 3 5     L62
Transmembrane 4 Superfamily Member 11 2     Membrane Component, Chromosome 3, Surface Marker 12
Membrane Component Chromosome 3 Surface Marker 12 3     Transmembrane 4 L6 Family Member 12

External Ids:    HGNC: 118531   Entrez Gene: 40712   Ensembl: ENSG000001699087   OMIM: 1911555   UniProtKB: P304083   

Export aliases for TM4SF1 gene to outside databases

Previous GC identifers: GC03U990049 GC03M149971 GC03M150368 GC03M150407 GC03M150569 GC03M146458


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for TM4SF1 Gene:
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin
family. Most of these members are cell-surface proteins that are characterized by the presence of four
hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell
development, activation, growth and motility. This encoded protein is a cell surface antigen and is highly
expressed in different carcinomas. (provided by RefSeq, Jul 2008)

GeneCards Summary for TM4SF1 Gene:
TM4SF1 (transmembrane 4 L six family member 1) is a protein-coding gene. An important paralog of this gene is ENSG00000273331.

Gene Wiki entry for TM4SF1 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000003.11  NC_018914.2  NT_005612.17  
Regulatory elements:
   Regulatory transcription factor binding sites in the TM4SF1 gene promoter:
         NF-1   HNF-1A   SRY   CBF-B   CBF-A   FOXO4   HNF-1   c-Myb   c-Jun   CBF(2)   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidTM4SF1 promoter sequence
   Search Chromatin IP Primers for TM4SF1

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat TM4SF1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 3q21-q25   Ensembl cytogenetic band:  3q25.1   HGNC cytogenetic band: 3q21-q25

TM4SF1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TM4SF1 gene location

GeneLoc information about chromosome 3         GeneLoc Exon Structure

GeneLoc location for GC03M149086:  view genomic region     (about GC identifiers)

Start:
149,086,805 bp from pter      End:
149,095,652 bp from pter
Size:
8,848 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: T4S1_HUMAN, P30408 (See protein sequence)
Recommended Name: Transmembrane 4 L6 family member 1  
Size: 202 amino acids; 21632 Da
Subunit: Present in high molecular weight complexes in tumor cells
Secondary accessions: Q6IB51

Explore the universe of human proteins at neXtProt for TM4SF1: NX_P30408

Explore proteomics data for TM4SF1 at MOPED

Post-translational modifications: 

  • Glycosylation2 at Asn129, Asn159

  • See TM4SF1 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_055035.1  
    ENSEMBL proteins: 
     ENSP00000304277   ENSP00000417084   ENSP00000419426   ENSP00000418025  

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    antibodies-online proteins for TM4SF1 (2 products) 

     
    antibodies-online peptides for TM4SF1

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    antibodies-online antibodies for TM4SF1 (54 products) 

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    1 InterPro protein domain:
     IPR008661 L6_membrane

    Graphical View of Domain Structure for InterPro Entry P30408

    ProtoNet protein and cluster: P30408

    1 Blocks protein domain: IPB008661 L6 membrane

    UniProtKB/Swiss-Prot: T4S1_HUMAN, P30408
    Similarity: Belongs to the L6 tetraspanin family


    Find genes that share domains with TM4SF1           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:
         Genatlas biochemistry entry for TM4SF1:
    transmembrane 4 superfamily member 1,membrane component chromosome 3,cell surface marker 1

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003674molecular_function ND--
         
    Find genes that share ontologies with TM4SF1           About GenesLikeMe


    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for TM4SF1

    miRNA
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    miRTarBase miRNAs that target TM4SF1:
    hsa-mir-128-3p (MIRT022021)

    Block miRNA regulation of human, mouse, rat TM4SF1 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate TM4SF1 (see all 17):
    hsa-miR-3607-3p hsa-miR-520d-5p hsa-miR-300 hsa-miR-200a hsa-miR-3916 hsa-miR-3125 hsa-miR-141 hsa-miR-3153
    SwitchGear 3'UTR luciferase reporter plasmidTM4SF1 3' UTR sequence
    Inhib. RNA
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    T4S1_HUMAN, P30408: Membrane; Multi-pass membrane protein
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    plasma membrane5
    nucleus1

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005887integral component of plasma membrane IDA7510285
    GO:0016021integral component of membrane ----

    Find genes that share ontologies with TM4SF1           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for TM4SF1
    Interactions:

        GeneGlobe Interaction Network for TM4SF1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for TM4SF1 (P304082, 3 ENSP000003042774) via UniProtKB, MINT, STRING, and/or I2D (see all 65)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    DDR1Q083452, 3MINT-63643 I2D: score=5 
    ENSG00000137332Q083452, 3MINT-63643 I2D: score=5 
    ENSG00000215522Q083452, 3MINT-63643 I2D: score=5 
    ENSG00000230456Q083452, 3MINT-63643 I2D: score=5 
    ENSG00000234078Q083452, 3MINT-63643 I2D: score=5 
    About this table

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008150biological_process ND--

    Find genes that share ontologies with TM4SF1           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for TM4SF1 (T4S1)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for TM4SF1 gene: 
    NM_014220.2  

    Unigene Cluster for TM4SF1:

    Transmembrane 4 L six family member 1
    Hs.351316  [show with all ESTs]
    Unigene Representative Sequence: AL832780
    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000305366(uc003exb.1) ENST00000472441(uc003exc.1) ENST00000493348
    ENST00000493298
    miRNA
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    Selected qRT-PCR Assays for microRNAs that regulate TM4SF1 (see all 17):
    hsa-miR-3607-3p hsa-miR-520d-5p hsa-miR-300 hsa-miR-200a hsa-miR-3916 hsa-miR-3125 hsa-miR-141 hsa-miR-3153
    SwitchGear 3'UTR luciferase reporter plasmidTM4SF1 3' UTR sequence
    Inhib. RNA
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    Primer
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    OriGene qPCR primer pairs and template standards for TM4SF1
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    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat TM4SF1
      QuantiTect SYBR Green Assays in human, mouse, rat TM4SF1
      QuantiFast Probe-based Assays in human, mouse, rat TM4SF1

    Additional mRNA sequence: 

    AK023364.1 AK093829.1 AK130073.1 AK130271.1 AL832780.1 BC008442.1 BC010166.2 BC034145.1 
    CR456953.1 X75684.1 

    Selected DOTS entries (see all 30):

    DT.97857021  DT.70102773  DT.91991467  DT.100884797  DT.91981673  DT.75100304  DT.120913546  DT.100884803 
    DT.100884802  DT.100884805  DT.100884809  DT.91908111  DT.100884796  DT.95373587  DT.120913533  DT.120913576 
    DT.85101176  DT.97864631  DT.100045040  DT.100677256  DT.100710264  DT.100884794  DT.102825807  DT.120913571 

    Selected AceView cDNA sequences (see all 1004):

    BM839156 AA988297 CA416391 BU677555 BF222820 BM764249 AI983655 AI823466 
    AI061065 BM905980 BF477735 CB158632 BF195127 AI565439 AI769516 AJ707152 
    BQ650836 BU628799 BM743191 CA413033 BQ776068 BM850928 CA445781 BM982001 

    GeneLoc Exon Structure

    5 Alternative Splicing Database (ASD) splice patterns (SP) for TM4SF1    About this scheme

    ExUns: 1a · 1b · 1c ^ 2a · 2b ^ 3a · 3b · 3c ^ 4a · 4b · 4c ^ 5a · 5b · 5c
    SP1:                                            -                                       
    SP2:                                -     -     -                                       
    SP3:                                      -     -     -                                 
    SP4:                                            -                                       
    SP5:                                                                                    


    ECgene alternative splicing isoforms for TM4SF1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    TM4SF1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GGGACGAGTG
    TM4SF1 Expression
    About this image


    TM4SF1 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 23) fully expand
     
     Kidney (Urinary System)    fully expand to see all 3 entries
             Metanephric Mesenchyme Cells Metanephric Mesenchyme
             S-shaped Body
     
     Neural Tube (Nervous System)    fully expand to see all 3 entries
             Floor Plate Cells Spinal Floor Plate
             Metencephalon
     
     Epithelial Cells
             Duct Cells Pancreatic Ducts
     
     Liver (Hepatobiliary System)    fully expand to see all 2 entries
             Periportal Hepatocytes Liver Lobule
     
     Pancreas (Endocrine System)
             Duct Cells Pancreatic Ducts
    TM4SF1 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    TM4SF1 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.351316

    UniProtKB/Swiss-Prot: T4S1_HUMAN, P30408
    Tissue specificity: Highly expressed in lung, breast, colon and ovarian carcinomas. It is also present on some
    normal cells, endothelial cells in particular

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    In Situ
    Assay Products:
     

     
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for TM4SF1 gene from Selected species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Tm4sf11 , 5 transmembrane 4 superfamily member 11, 5 82.84(n)1
    78.22(a)1
      3 (27.68 cM)5
    171121  NM_008536.31  NP_032562.11 
     572870645 
    chicken
    (Gallus gallus)
    Aves TM4SF11 transmembrane 4 L six family member 1 63.2(n)
    64.36(a)
      425046  NM_001277478.1  NP_001264407.1 
    lizard
    (Anolis carolinensis)
    Reptilia --
    Uncharacterized protein
    40(a)
    many ↔ many
    3(196015655-196033465)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.187172 Xenopus laevis transcribed sequence with moderate similarity more 75.98(n)    BX851640.1 
    zebrafish
    (Danio rerio)
    Actinopterygii tm4sf186
    transmembrane 4 L six family member 18
    48(a)
    1 → many
    22(41118693-41127009) ENSDARG00000060668


    ENSEMBL Gene Tree for TM4SF1 (if available)
    TreeFam Gene Tree for TM4SF1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for TM4SF1 gene
    ENSG000002733312  TM4SF42  TM4SF52  TM4SF192  TM4SF182  
    4 SIMAP similar genes for TM4SF1 using alignment to 5 protein entries:     T4S1_HUMAN (see all proteins):
    TM4SF4    TM4SF18    TM4SF5    TM4SF19

    Find genes that share paralogs with TM4SF1           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for TM4SF1 (see all 252)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 3 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1472413711,2
    --149086463(+) TTTCTA/GTAGAA 1 -- ds50010--------
    rs1900811981,2
    --149086629(+) CAATGA/GCAATT 1 -- ds50010--------
    rs355256971,2
    C,F--149086665(+) GAAAGA/TGGATG 1 -- ds50017Minor allele frequency- T:0.18NA WA EA 366
    rs1120392131,2
    F--149086715(+) AGCAAT/CAGGGG 1 -- ds50012Minor allele frequency- C:0.04CSA WA 120
    rs1826602631,2
    --149086722(+) GGGGCA/CACATA 1 -- ds50010--------
    rs768060881,2
    C--149086749(+) AAAAA-/AAGGGGGG 1 -- ds50010--------
    rs1399514171,2
    C--149086750(+) AAAAA-/AGGGGGG 1 -- ds50010--------
    rs2001205951,2
    C--149086750(+) AAAAAA/GGGGGG 1 -- ds50010--------
    rs113288801,2
    C,F--149086751(+) GGGGG-/AG/G  
            
    AGAAA
    1 -- ds50012NA 4
    rs1393691721,2
    C--149086791(+) AATGAA/CACTAA 1 -- ds50010--------

    HapMap Linkage Disequilibrium report for TM4SF1 (149086805 - 149095652 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for TM4SF1: --
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing TM4SF1
    DNA2.0 Custom Variant and Variant Library Synthesis for TM4SF1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 191155    OMIM disorders: --


    Find genes that share disorders with TM4SF1           About GenesLikeMe


    Export disorders for TM4SF1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for TM4SF1 gene, integrated from 10 sources (see all 27):
    (articles sorted by number of sources associating them with TM4SF1)
        Utopia: connect your pdf to the dynamic
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    1. Cloning and expression of the tumor-associated antigen L6. (PubMed id 1565644)1, 2, 3 Marken J.S.... Aruffo A. (Proc. Natl. Acad. Sci. U.S.A. 1992)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    3. Membrane topology of the L6 antigen and identification of the protein epitope recognized by the L6 monoclonal antibody. (PubMed id 7510285)1, 2 Marken J.S.... Aruffo A. (J. Biol. Chem. 1994)
    4. Chromosomal localization of three human genes coding for A15, L6, and S5.7 (TAPA1): all members of the transmembrane 4 superfamily of proteins. (PubMed id 8168850)1, 9 Virtaneva K.I....SchrAPder J.P. (Immunogenetics 1994)
    5. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (BMC Syst. Biol. 2011)
    6. TM4SF1: a tetraspanin-like protein necessary for nanopodia formation and endothelial cell migration. (PubMed id 21626280)1 Zukauskas A....Jaminet S.C. (Angiogenesis 2011)
    7. Genes associated with prognosis after surgery for malignant pleural mesothelioma promote tumor cell survival in vitro. (PubMed id 21569526)1 Gordon G.J....Sugarbaker D.J. (BMC Cancer 2011)
    8. Combined omics analysis identifies transmembrane 4 L6 family member 1 as a surface protein marker specific to human mesenchymal stem cells. (PubMed id 20486778)1 Bae S....Kim H. (Stem Cells Dev. 2011)
    9. TM4SF1, a novel primary androgen receptor target gene over-expressed in human prostate cancer and involved in cell migration. (PubMed id 21656834)1 Allioli N....Samarut J. (Prostate 2011)
    10. Ubiquitin ligase substrate identification through quantitative proteomics at both the protein and peptide levels. (PubMed id 21987572)1 Lee K.A....Doedens J.R. (J. Biol. Chem. 2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 4071 HGNC: 11853 AceView: TM4SF1 Ensembl:ENSG00000169908 euGenes: HUgn4071
    ECgene: TM4SF1 H-InvDB: TM4SF1

    (According to HUGE)
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    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for TM4SF1 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for TM4SF1 Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for TM4SF1 gene:
    Search GeneIP for patents involving TM4SF1

    GeneCards and IP:
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