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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

TM4SF1 Gene

protein-coding   GIFtS: 53
GCID: GC03M149086

Transmembrane 4 L Six Family Member 1

(Previous name: transmembrane 4 superfamily member 1)
(Previous symbol: M3S1)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Transmembrane 4 L Six Family Member 11 2     Tumor-Associated Antigen L62 3
M3S11 2 3 5     H-L62
TAAL62 3 5     L62
Transmembrane 4 Superfamily Member 11 2     Membrane Component, Chromosome 3, Surface Marker 12
Membrane Component Chromosome 3 Surface Marker 12 3     Transmembrane 4 L6 Family Member 12

External Ids:    HGNC: 118531   Entrez Gene: 40712   Ensembl: ENSG000001699087   OMIM: 1911555   UniProtKB: P304083   

Export aliases for TM4SF1 gene to outside databases

Previous GC identifers: GC03U990049 GC03M149971 GC03M150368 GC03M150407 GC03M150569 GC03M146458


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for TM4SF1 Gene:
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin
family. Most of these members are cell-surface proteins that are characterized by the presence of four
hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell
development, activation, growth and motility. This encoded protein is a cell surface antigen and is highly
expressed in different carcinomas. (provided by RefSeq, Jul 2008)

GeneCards Summary for TM4SF1 Gene: 
TM4SF1 (transmembrane 4 L six family member 1) is a protein-coding gene. Diseases associated with TM4SF1 include lung cancer, and gastric cancer. GO annotations related to this gene include molecular_function. An important paralog of this gene is TM4SF4.

Gene Wiki entry for TM4SF1 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000003.11  NT_005612.16  NC_018914.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the TM4SF1 gene promoter:
         NF-1   HNF-1A   SRY   CBF-B   CBF-A   FOXO4   HNF-1   c-Myb   c-Jun   CBF(2)   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidTM4SF1 promoter sequence
   Search SABiosciences Chromatin IP Primers for TM4SF1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TM4SF1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 3q21-q25   Ensembl cytogenetic band:  3q25.1   HGNC cytogenetic band: 3q21-q25

TM4SF1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TM4SF1 gene location

GeneLoc information about chromosome 3         GeneLoc Exon Structure

GeneLoc location for GC03M149086:  view genomic region     (about GC identifiers)

Start:
149,086,805 bp from pter      End:
149,095,652 bp from pter
Size:
8,848 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: T4S1_HUMAN, P30408 (See protein sequence)
Recommended Name: Transmembrane 4 L6 family member 1  
Size: 202 amino acids; 21632 Da
Subunit: Present in high molecular weight complexes in tumor cells
Subcellular location: Membrane; Multi-pass membrane protein
Secondary accessions: Q6IB51

Explore the universe of human proteins at neXtProt for TM4SF1: NX_P30408

Explore proteomics data for TM4SF1 at MOPED 

TM4SF1 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

TM4SF1 Protein Expression

REFSEQ proteins: NP_055035.1  
ENSEMBL proteins: 
 ENSP00000304277   ENSP00000417084   ENSP00000419426   ENSP00000418025  

Human Recombinant Protein Products for TM4SF1: 
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Cloud-Clone Corp. Proteins for TM4SF1 

Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0005887integral to plasma membrane IDA7510285
GO:0016021integral to membrane ----

TM4SF1 for ontologies           About GeneDecksing



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Cloud-Clone Corp. CLIAs for TM4SF1


(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section
1 InterPro protein domain:
 IPR008661 L6_membrane

Graphical View of Domain Structure for InterPro Entry P30408

ProtoNet protein and cluster: P30408

1 Blocks protein domain: IPB008661 L6 membrane

UniProtKB/Swiss-Prot: T4S1_HUMAN, P30408
Similarity: Belongs to the L6 tetraspanin family


TM4SF1 for domains           About GeneDecksing


(According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
About This Section

Molecular Function:
     Genatlas biochemistry entry for TM4SF1:
transmembrane 4 superfamily member 1,membrane component chromosome 3,cell surface marker 1

     Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0003674molecular_function ND--
     
TM4SF1 for ontologies           About GeneDecksing


Animal Models:
   inGenious Targeting Laboratory - Custom generated mouse model solutions for TM4SF1 
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   genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for TM4SF1 
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miRNA
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hsa-miR-3607-3p hsa-miR-520d-5p hsa-miR-300 hsa-miR-200a hsa-miR-3916 hsa-miR-3125 hsa-miR-141 hsa-miR-3153
SwitchGear 3'UTR luciferase reporter plasmidTM4SF1 3' UTR sequence
Inhib. RNA
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Gene Editing
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Clone
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In Situ Assay
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Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TM4SF1


(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
About This Section



Interactions:

    SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for TM4SF1

STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

5/65 Interacting proteins for TM4SF1 (P304082, 3 ENSP000003042774) via UniProtKB, MINT, STRING, and/or I2D (see all 65)
InteractantInteraction Details
GeneCardExternal ID(s)
DDR1Q083452, 3MINT-63643 I2D: score=5 
ENSG00000137332Q083452, 3MINT-63643 I2D: score=5 
ENSG00000215522Q083452, 3MINT-63643 I2D: score=5 
ENSG00000230456Q083452, 3MINT-63643 I2D: score=5 
ENSG00000234078Q083452, 3MINT-63643 I2D: score=5 
About this table

Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0008150biological_process ND--

TM4SF1 for ontologies           About GeneDecksing



(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section
Browse Small Molecules at EMD Millipore
Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for TM4SF1 (T4S1)

Search CenterWatch for drugs/clinical trials and news about TM4SF1 / T4S1

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for TM4SF1 gene: 
NM_014220.2  

Unigene Cluster for TM4SF1:

Transmembrane 4 L six family member 1
Hs.351316  [show with all ESTs]
Unigene Representative Sequence: AL832780
4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
ENST00000305366(uc003exb.1) ENST00000472441(uc003exc.1) ENST00000493348
ENST00000493298
miRNA
Products:
     
QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat TM4SF1
8/17 QIAGEN miScript miRNA Assays for microRNAs that regulate TM4SF1 (see all 17):
hsa-miR-3607-3p hsa-miR-520d-5p hsa-miR-300 hsa-miR-200a hsa-miR-3916 hsa-miR-3125 hsa-miR-141 hsa-miR-3153
SwitchGear 3'UTR luciferase reporter plasmidTM4SF1 3' UTR sequence
Inhib. RNA
Products:
     
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Clone
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DNA2.0 Custom Codon Optimized Gene Synthesis Service for TM4SF1
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TM4SF1
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                     Customized lentivirus expression plasmids for stable overexpression of TM4SF1 
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  QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TM4SF1

Additional mRNA sequence: 

AK023364.1 AK093829.1 AK130073.1 AK130271.1 AL832780.1 BC008442.1 BC010166.2 BC034145.1 
CR456953.1 X75684.1 

24/30 DOTS entries (see all 30):

DT.97857021  DT.70102773  DT.91991467  DT.100884797  DT.91981673  DT.75100304  DT.120913546  DT.100884803 
DT.100884802  DT.100884805  DT.100884809  DT.91908111  DT.100884796  DT.95373587  DT.120913533  DT.120913576 
DT.85101176  DT.97864631  DT.100045040  DT.100677256  DT.100710264  DT.100884794  DT.102825807  DT.120913571 

24/1004 AceView cDNA sequences (see all 1004):

AI744767 AA037696 CA417099 BM843283 AA345349 BM888314 BU628096 BF195127 
AI859160 BP349755 BQ004397 AA136658 BM827306 AA487893 CD678204 BQ084342 
BM982001 BM976068 CA306032 AA524526 CA435242 CF127633 AA376086 CD368738 

GeneLoc Exon Structure

5 Alternative Splicing Database (ASD) splice patterns (SP) for TM4SF1    About this scheme

ExUns: 1a · 1b · 1c ^ 2a · 2b ^ 3a · 3b · 3c ^ 4a · 4b · 4c ^ 5a · 5b · 5c
SP1:                                            -                                       
SP2:                                -     -     -                                       
SP3:                                      -     -     -                                 
SP4:                                            -                                       
SP5:                                                                                    


ECgene alternative splicing isoforms for TM4SF1

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

TM4SF1 expression in normal human tissues (normalized intensities)      TM4SF1 embryonic expression: see
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>2/3
CGAP TAG: GGGACGAGTG
TM4SF1 Expression
About this image


TM4SF1 expression in embryonic tissues and stem cells    About this table
Data from LifeMap, the Embryonic Development and Stem Cells Database 
 5/17 selected tissues (see all 17) fully expand
 
 Neural Tube (Nervous System)    fully expand to see all 3 entries
         Floor Plate Cells Spinal Floor Plate
         Metencephalon
 
 Kidney (Urinary System)    fully expand to see all 3 entries
         Metanephric Mesenchyme Cells Metanephric Mesenchyme
         S-shaped Body
 
 Endothelium (Cardiovascular System)    fully expand to see all 2 entries
         Peripheral blood endothelial colony-forming cells
         Endothelial-like cells ( Derivation and purification of endothelial precursor cells...
 
 Bone (Muscoskeletal System)    fully expand to see all 2 entries
         Zeugopod Epiphyseal End
         Human Vertebral Mesenchymal Stem Cells (HVMSC)   
 
 Heart (Cardiovascular System)    fully expand to see all 2 entries
         Dorsal Aorta
         Cardiac Myocytes   

See TM4SF1 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for TM4SF1

SOURCE GeneReport for Unigene cluster: Hs.351316

UniProtKB/Swiss-Prot: T4S1_HUMAN, P30408
Tissue specificity: Highly expressed in lung, breast, colon and ovarian carcinomas. It is also present on some
normal cells, endothelial cells in particular

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QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TM4SF1
In Situ
Assay Products:
 

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TM4SF1

(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of chordates.

Orthologs for TM4SF1 gene from 5/11 species (see all 11)    About this table
Organism Taxonomic
classification
Gene Description Human
Similarity
Orthology
Type
Details
mouse
(Mus musculus)
Mammalia Tm4sf11 , 5 transmembrane 4 superfamily member 11, 5 82.84(n)1
78.22(a)1
  3 (27.68 cM)5
171121  NM_008536.31  NP_032562.11 
 572870645 
chicken
(Gallus gallus)
Aves TM4SF11 transmembrane 4 L six family member 1 63.2(n)
64.36(a)
  425046  XM_422848.3  XP_422848.2 
lizard
(Anolis carolinensis)
Reptilia --
Uncharacterized protein
40(a)
possible ortholog
3(196015655-196033465)
African clawed frog
(Xenopus laevis)
Amphibia Xl.187172 Xenopus laevis transcribed sequence with moderate similarity more 75.98(n)    BX851640.1 
zebrafish
(Danio rerio)
Actinopterygii tm4sf186
CABZ01033205.26
uncharacterized protein LOC100002960
46(a)
42(a)
1 ↔ many
possible ortholog
22(41118693-41127009)
15(139321-145563)


ENSEMBL Gene Tree for TM4SF1 (if available)
TreeFam Gene Tree for TM4SF1 (if available)

(Paralogs according to 1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
Paralogs for TM4SF1 gene
TM4SF42  TM4SF52  TM4SF192  TM4SF182  
4 SIMAP similar genes for TM4SF1 using alignment to 5 protein entries:     T4S1_HUMAN (see all proteins):
TM4SF4    TM4SF18    TM4SF5    TM4SF19

TM4SF1 for paralogs           About GeneDecksing



(SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

10/252 SNPs in TM4SF1 are shown (see all 252)    About this table     
Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidClinical
significance
Chr 3 posSequence#AA
Chg
TypeMore#Allele
freq
PopTotal
sample
More
----------
rs1472413711,2
--149086463(+) TTTCTA/GTAGAA 1 -- ds50010--------
rs1900811981,2
--149086629(+) CAATGA/GCAATT 1 -- ds50010--------
rs355256971,2
C,F--149086665(+) GAAAGA/TGGATG 1 -- ds50017Minor allele frequency- T:0.18NA WA EA 366
rs1120392131,2
F--149086715(+) AGCAAT/CAGGGG 1 -- ds50012Minor allele frequency- C:0.04CSA WA 120
rs1826602631,2
--149086722(+) GGGGCA/CACATA 1 -- ds50010--------
rs768060881,2
C--149086749(+) AAAAA-/AAGGGGGG 1 -- ds50010--------
rs1399514171,2
C--149086750(+) AAAAA-/AGGGGGG 1 -- ds50010--------
rs2001205951,2
C--149086750(+) AAAAAA/GGGGGG 1 -- ds50010--------
rs113288801,2
C,F--149086751(+) GGGGG-/AG/G  
        
AGAAA
1 -- ds50012NA 4
rs1393691721,2
C--149086791(+) AATGAA/CACTAA 1 -- ds50010--------

HapMap Linkage Disequilibrium report for TM4SF1 (149086805 - 149095652 bp)

Structural Variations
      Database of Genomic Variants (DGV) variations for TM4SF1: --
SABiosciences Cancer Mutation PCR Assays
SeqTarget long-range PCR primers for resequencing TM4SF1
DNA2.0 Custom Variant and Variant Library Synthesis for TM4SF1

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section
OMIM gene information: 191155    OMIM disorders: --

5 diseases for TM4SF1:    About MalaCards
lung cancer    gastric cancer    endotheliitis    prostate cancer
prostatitis


TM4SF1 for disorders           About GeneDecksing


Export disorders for TM4SF1 gene to outside databases

(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
About This Section

PubMed articles for TM4SF1 gene, integrated from 9 sources (see all 27):
(articles sorted by number of sources associating them with TM4SF1)
    Utopia: connect your pdf to the dynamic
world of online information

  1. Cloning and expression of the tumor-associated antigen L6. (PubMed id 1565644)1, 2, 3 Marken J.S.... Aruffo A. (1992)
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
  3. Membrane topology of the L6 antigen and identification of the protein epitope recognized by the L6 monoclonal antibody. (PubMed id 7510285)1, 2 Marken J.S.... Aruffo A. (1994)
  4. Chromosomal localization of three human genes coding for A15, L6, and S5.7 (TAPA1): all members of the transmembrane 4 superfamily of proteins. (PubMed id 8168850)1, 9 Virtaneva K.I....Schroder J.P. (1994)
  5. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
  6. TM4SF1: a tetraspanin-like protein necessary for nano podia formation and endothelial cell migration. (PubMed id 21626280)1 Zukauskas A....Jaminet S.C. (2011)
  7. Genes associated with prognosis after surgery for mal ignant pleural mesothelioma promote tumor cell survival in vitro. (PubMed id 21569526)1 Gordon G.J....Sugarbaker D.J. (2011)
  8. Combined omics analysis identifies transmembrane 4 L6 family member 1 as a surface protein marker specific to human mesenchymal stem cells. (PubMed id 20486778)1 Bae S....Kim H. (2011)
  9. TM4SF1, a novel primary androgen receptor target gene over-expressed in human prostate cancer and involved in cell migration. (PubMed id 21656834)1 Allioli N....Samarut J. (2011)
  10. Ubiquitin ligase substrate identification through qua ntitative proteomics at both the protein and peptide levels. (PubMed id 21987572)1 Lee K.A....Doedens J.R. (2011)

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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 4071 HGNC: 11853 AceView: TM4SF1 Ensembl:ENSG00000169908 euGenes: HUgn4071
ECgene: TM4SF1 H-InvDB: TM4SF1

(According to HUGE)
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(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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NameDescription
PharmGKB entry for TM4SF1 Pharmacogenomics, SNPs, Pathways
ATLAS Chromosomes in Cancer entry for TM4SF1 Genetics and Cytogenetics in Oncology and Haematology

(Patent information from GeneIP,
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