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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

TM2D1 Gene

protein-coding   GIFtS: 44
GCID: GC01M062146

TM2 Domain Containing 1

Alzheimer's & Parkinson's Diseases Congress
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
TM2 Domain Containing 11 2
Beta-Amyloid-Binding Protein2 3
BBP2 3
hBBP2 3
TM2 Domain-Containing Protein 12

External Ids:    HGNC: 241421   Entrez Gene: 839412   Ensembl: ENSG000001626047   OMIM: 6100805   UniProtKB: Q9BX743   

Export aliases for TM2D1 gene to outside databases

Previous GC identifers: GC01M061859 GC01M060259


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for TM2D1 Gene:
The protein encoded by this gene is a beta-amyloid peptide-binding protein. It contains a structural module
related to that of the seven transmembrane domain G protein-coupled receptor superfamily and known to be
important in heterotrimeric G protein activation. Beta-amyloid peptide has been established to be a causative
factor in neuron death and the consequent diminution of cognitive abilities observed in Alzheimer's disease. This
protein may be a target of neurotoxic beta-amyloid peptide, and may mediate cellular vulnerability to
beta-amyloid peptide toxicity through a G protein-regulated program of cell death. (provided by RefSeq, Dec 2008)

GeneCards Summary for TM2D1 Gene: 
TM2D1 (TM2 domain containing 1) is a protein-coding gene. Diseases associated with TM2D1 include traumatic brain injury, and brain injury. An important paralog of this gene is TM2D3.

UniProtKB/Swiss-Prot: TM2D1_HUMAN, Q9BX74
Function: May participate in beta-amyloid-induced apoptosis via its interaction with beta-APP42




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000001.10  NT_032977.9  NC_018912.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the TM2D1 gene promoter:
         LHX3b/Lhx3b   Elk-1   Nkx2-2   GATA-1   CREB   IRF-2   Pax-3   GATA-6   LHX3a/Lhx3a   Pax-4a   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidTM2D1 promoter sequence
   Search SABiosciences Chromatin IP Primers for TM2D1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TM2D1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1p31.3   Ensembl cytogenetic band:  1p31.3   HGNC cytogenetic band: 1p32.1

TM2D1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TM2D1 gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01M062146:  view genomic region     (about GC identifiers)

Start:
62,146,718 bp from pter      End:
62,191,095 bp from pter
Size:
44,378 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: TM2D1_HUMAN, Q9BX74 (See protein sequence)
Recommended Name: TM2 domain-containing protein 1 precursor  
Size: 207 amino acids; 22327 Da
Subunit: Interacts with beta-APP42 (beta-amyloid protein 42) peptide of APP
Subcellular location: Membrane; Multi-pass membrane protein
Caution: Was originally (PubMed:11278849) thought to modulate beta-amyloid toxicity by coupling to G protein.
However, PubMed:12836168 showed that this effect is not direct
Secondary accessions: A6NDA8

Explore the universe of human proteins at neXtProt for TM2D1: NX_Q9BX74

Explore proteomics data for TM2D1 at MOPED 

Post-translational modifications:

  • UniProtKB: N-glycosylated
  • View neXtProt modification sites for NX_Q9BX74

  • TM2D1 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    TM2D1 Protein Expression
    REFSEQ proteins: NP_114416.1  
    ENSEMBL proteins: 
     ENSP00000475700   ENSP00000360222   ENSP00000476178   ENSP00000475186   ENSP00000475844  
     ENSP00000475529   ENSP00000475297   ENSP00000294613  

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    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for TM2D1 

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005887integral to plasma membrane ----
    GO:0016021integral to membrane IEA--

    TM2D1 for ontologies           About GeneDecksing



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    Cloud-Clone Corp. CLIAs for TM2D1


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    1 InterPro protein domain:
     IPR007829 TM2

    Graphical View of Domain Structure for InterPro Entry Q9BX74

    ProtoNet protein and cluster: Q9BX74

    UniProtKB/Swiss-Prot: TM2D1_HUMAN, Q9BX74
    Similarity: Belongs to the TM2 family


    TM2D1 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: TM2D1_HUMAN, Q9BX74
    Function: May participate in beta-amyloid-induced apoptosis via its interaction with beta-APP42

         Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0001540beta-amyloid binding ----
    GO:0004930G-protein coupled receptor activity ----
         
    TM2D1 for ontologies           About GeneDecksing


    Phenotypes:
         1 MGI phenotypic allele for Tm2d1 (no phenotypes)

    TM2D1 for phenotypes           About GeneDecksing

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for TM2D1 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for TM2D1

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for TM2D1 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for TM2D1 

    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat TM2D1
    2 QIAGEN miScript miRNA Assays for microRNAs that regulate TM2D1:
    hsa-miR-3662 hsa-miR-216a
    SwitchGear 3'UTR luciferase reporter plasmidTM2D1 3' UTR sequence
    Inhib. RNA
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    GenScript: all cDNA clones in your preferred vector: TM2D1 (NM_032027)
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                         Customized lentivirus expression plasmids for stable overexpression of TM2D1 

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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TM2D1


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for TM2D1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 18)

    5/19 Interacting proteins for TM2D1 (Q9BX743 ENSP000003602224) via UniProtKB, MINT, STRING, and/or I2D (see all 19)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    APPP050673, ENSP000002849814I2D: score=2 STRING: ENSP00000284981
    FAM212BQ9NTI73I2D: score=1 
    ARTNENSP000003919984STRING: ENSP00000391998
    CTNNBIP1ENSP000003664664STRING: ENSP00000366466
    ENSG00000225073ENSP000004003264STRING: ENSP00000400326
    About this table

    Gene Ontology (GO): 3 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006915apoptotic process IEA--
    GO:0007186G-protein coupled receptor signaling pathway ----
    GO:0097190apoptotic signaling pathway ----

    TM2D1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for TM2D1

    Search CenterWatch for drugs/clinical trials and news about TM2D1

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for TM2D1 gene: 
    NM_032027.2  

    Unigene Cluster for TM2D1:

    TM2 domain containing 1
    Hs.656790  [show with all ESTs]
    Unigene Representative Sequence: AK311444
    12 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000606498 ENST00000472357 ENST00000371180 ENST00000488206 ENST00000472989
    ENST00000488410 ENST00000468586 ENST00000371178 ENST00000494926 ENST00000496465
    ENST00000371177 ENST00000294613(uc001czz.1)

    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat TM2D1
    2 QIAGEN miScript miRNA Assays for microRNAs that regulate TM2D1:
    hsa-miR-3662 hsa-miR-216a
    SwitchGear 3'UTR luciferase reporter plasmidTM2D1 3' UTR sequence
    Inhib. RNA
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    Browse for Gene Knock-down Tools from EMD Millipore
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    GenScript: all cDNA clones in your preferred vector: TM2D1 (NM_032027)
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    Primer
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    OriGene qPCR primer pairs and template standards for TM2D1
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    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat TM2D1
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TM2D1
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TM2D1

    Additional mRNA sequence: 

    AF353990.1 AK311444.1 AK311705.1 BC029486.1 BC048995.1 

    12 DOTS entries:

    DT.452370  DT.121375460  DT.92429688  DT.40121277  DT.121375478  DT.92429679  DT.95278078  DT.100783510 
    DT.121375464  DT.99936501  DT.121375491  DT.97765281 

    24/197 AceView cDNA sequences (see all 197):

    NM_032027 AW182809 BC029486 AI903938 CA415155 AI245878 BU664262 AI732252 
    AI479764 AV650355 AI349520 BI324832 AI350984 AI299329 CA307180 AI554871 
    BX108300 CA417481 CA418546 AI682204 BM711173 CA449839 Z38337 AA252976 

    GeneLoc Exon Structure

    5/8 Alternative Splicing Database (ASD) splice patterns (SP) for TM2D1 (see all 8)    About this scheme

    ExUns: 1a · 1b · 1c · 1d · 1e · 1f ^ 2 ^ 3a · 3b ^ 4 ^ 5 ^ 6 ^ 7 ^ 8a · 8b ^ 9a · 9b ^ 10a · 10b ^ 11
    SP1:                                -     -                             -     -           -     -     -                     
    SP2:                                            -                       -     -                                             
    SP3:                                      -     -                       -     -                                             
    SP4:                                -     -                                                                                 
    SP5:                                -     -                             -     -                                             


    ECgene alternative splicing isoforms for TM2D1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TM2D1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    TM2D1 Expression
    About this image


    See TM2D1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for TM2D1

    SOURCE GeneReport for Unigene cluster: Hs.656790

    UniProtKB/Swiss-Prot: TM2D1_HUMAN, Q9BX74
    Tissue specificity: Widely expressed

        SABiosciences Expression via Pathway-Focused PCR Array including TM2D1: 
              G Protein Coupled Receptors 384HT in human mouse rat

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TM2D1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for TM2D1 gene from 6/15 species (see all 15)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Tm2d11 , 5 TM2 domain containing 11, 5 85.67(n)1
    85.51(a)1
      4 (45.60 cM)5
    940431  NM_053157.21  NP_444387.11 
     983553705 
    chicken
    (Gallus gallus)
    Aves TM2D11 TM2 domain containing 1 72.53(n)
    73.87(a)
      775978  XM_001235552.2  XP_001235553.2 
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.164762 Xenopus laevis transcribed sequence with moderate similarity more 77.95(n)    BJ036034.1 
    zebrafish
    (Danio rerio)
    Actinopterygii tm2d11 TM2 domain containing 1 64.86(n)
    71.69(a)
      100093710  NM_001099263.1  NP_001092733.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG107951 CG10795 50(n)
    46.62(a)
      37443  NM_137739.2  NP_611583.1 
    worm
    (Caenorhabditis elegans)
    Secernentea Y66D12A.211 Protein Y66D12A.21 48.92(n)
    37.66(a)
      176581  NM_067080.2  NP_499481.1 


    ENSEMBL Gene Tree for TM2D1 (if available)
    TreeFam Gene Tree for TM2D1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for TM2D1 gene
    TM2D32  

    TM2D1 for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for TM2D1
    PGOHUM00000237701


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/969 SNPs in TM2D1 are shown (see all 969)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1854125891,2
    --62146219(+) AAATCA/GGTGCT 1 -- ds50010--------
    rs1894223711,2
    --62146370(+) ACTGCA/GGTGAG 1 -- ds50010--------
    rs112078081,2
    C,F,A,H--62146438(+) AGGAAG/AAAGTT 1 -- ds500128Minor allele frequency- A:0.34NA NS EA WA CSA 2490
    rs1480262101,2
    --62146522(+) TTTAGC/TTCCCT 1 -- ds50010--------
    rs1417417681,2
    C--62146602(+) CCCCAG/TGCAAT 1 -- ds50010--------
    rs758445591,2
    C,F--62146649(+) TTGAAG/AGATCA 1 -- ds50011Minor allele frequency- A:0.02WA 118
    rs1472009541,2
    C--62146662(+) ATGGGC/TAAGAC 1 -- ds50010--------
    rs412894201,2
    --62146778(+) CCTTTC/GTAAAA 1 -- ut310--------
    rs595624571,2
    C--62146788(+) AGATT-/AAAGAGT 1 -- ut310--------
    rs767949161,2
    C,F--62146961(+) ATGAAA/TAAGAG 1 -- ut312Minor allele frequency- T:0.04CSA WA 120

    HapMap Linkage Disequilibrium report for TM2D1 (62146718 - 62191095 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for TM2D1: --
    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing TM2D1
    DNA2.0 Custom Variant and Variant Library Synthesis for TM2D1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 610080    OMIM disorders: --

    5 diseases for TM2D1:    About MalaCards
    traumatic brain injury    brain injury    hypospadias    alzheimer's disease
    neuronitis


    TM2D1 for disorders           About GeneDecksing


    Congresses - knowledge worth sharing:  
    Alzheimer's & Parkinson's Diseases Congress (ADPD) 18 - 22 March 2015

    1 Novoseek inferred disease relationship for TM2D1 gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    alzheimers disease 50.4 3 19376274 (1), 20477378 (1), 10760475 (1)


    Export disorders for TM2D1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for TM2D1 gene, integrated from 9 sources (see all 18):
    (articles sorted by number of sources associating them with TM2D1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Beta-amyloid peptide-induced apoptosis regulated by a novel protein containing a G protein activation module. (PubMed id 11278849)1, 2, 3 Kajkowski E.M.... Ozenberger B.A. (2001)
    2. Beta-amyloid peptide binding protein does not couple to G protein in a heterologous Xenopus expression system. (PubMed id 12836168)1, 2, 9 Lee Y.... Kaang B.-K. (2003)
    3. The secretory beta-amyloid precursor protein is a motogen for human epidermal keratinocytes. (PubMed id 12553667)1, 3 Kirfel G....Herzog V. (2002)
    4. Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)
    5. Ubiquitin-mediated proteolysis of HuR by heat shock. (PubMed id 19322201)1 Abdelmohsen K....Gorospe M. (2009)
    6. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PubMed id 17207965)1 Lamesch P.... Vidal M. (2007)
    7. The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)2 Gregory S.G.... Bentley D.R. (2006)
    8. The low density lipoprotein receptor-related protein 1B retains beta-amyloid precursor protein at the cell surface and reduces amyloid-beta peptide production. (PubMed id 15126508)1 Cam J.A....Bu G. (2004)
    9. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
    10. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 83941 HGNC: 24142 AceView: BBP Ensembl:ENSG00000162604 euGenes: HUgn83941
    ECgene: TM2D1 H-InvDB: TM2D1

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for TM2D1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for TM2D1 gene:
    Search GeneIP for patents involving TM2D1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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