Aliases for TLX3 Gene
External Ids for TLX3 Gene
Previous HGNC Symbols for TLX3 Gene
Previous GeneCards Identifiers for TLX3 Gene
The protein encoded by this gene is an orphan homeobox protein that encodes a DNA-binding nuclear transcription factor. A translocation [t(5;14)(q35;q32)] involving this gene is associated with T-cell acute lymphoblastic leukemia (T-ALL) in children and young adults. [provided by RefSeq, Nov 2015]
GeneCards Summary for TLX3 Gene
TLX3 (T-Cell Leukemia Homeobox 3) is a Protein Coding gene. Diseases associated with TLX3 include precursor t-cell acute lymphoblastic leukemia and t-cell leukemia. Among its related pathways are Transcriptional misregulation in cancer and SIDS Susceptibility Pathways. GO annotations related to this gene include sequence-specific DNA binding. An important paralog of this gene is NKX2-5.