TLR8 Gene
protein-coding GIFtS: 63
GCID: GC0XP012924
|
|
toll-like receptor 8
| |
Aliases
for TLR8 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Toll-Like Receptor 81 2 | | CD2881 2 | | CD288 Antigen3 |
Export aliases for TLR8 gene to outside databasesPrevious GC identifers: GC0XP012117 GC0XP011690 GC0XP012221 GC0XP012286 GC0XP012684 GC0XP012834 GC0XP010691 |
Summaries
for TLR8 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for TLR8:
The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role inpathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and sharestructural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that areexpressed on infectious agents, and mediate the production of cytokines necessary for the development of effectiveimmunity. The various TLRs exhibit different patterns of expression. This gene is predominantly expressed in lung andperipheral blood leukocytes, and lies in close proximity to another family member, TLR7, on chromosome X. (provided byRefSeq, Jul 2008)
UniProtKB/Swiss-Prot: TLR8_HUMAN, Q9NR97Function: Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune responseagainst pathogens through recognition of molecular patterns specific to microorganisms. Acts via MYD88 and TRAF6,leading to NF-kappa-B activation, cytokine secretion and the inflammatory response
Gene Wiki entry for TLR8
|
Genomic Views
for TLR8 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000023.10 NC_018934.1 NT_167197.1
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the TLR8 gene promoter:
CHOP-10 Sox5 FAC1 STAT1 IRF-7A C/EBPalpha
Other transcription factors
Search SABiosciences Chromatin IP Primers for TLR8
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TLR8 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: Xp22 Ensembl cytogenetic band: Xp22.2 HGNC cytogenetic band: Xp22TLR8 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome X GeneLoc Exon Structure GeneLoc location for GC0XP012924: view genomic region
(about GC identifiers)
Start:
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12,924,739 bp from pter |
End:
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12,941,288 bp from pter |
Size:
|
16,550 bases |
Orientation:
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plus strand |
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Proteins
for TLR8 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: TLR8_HUMAN, Q9NR97 (See
protein sequence)Recommended Name: Toll-like receptor 8 precursor Size: 1041 amino acids; 119828 Da
Subunit: Interacts with MYD88 via their respective TIR domains. Interacts with UNC93B1 (By similarity). Interacts withBTK
Subcellular location: Membrane; Single-pass type I membrane protein (By similarity)
Secondary accessions: B3Y654 Q495P4 Q6UXL6 Q9NYG9Explore the universe of human proteins at neXtProt for TLR8: NX_Q9NR97
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9NR97
TLR8 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_619542.1
ENSEMBL proteins: ENSP00000218032 ENSP00000312082 Reactome Protein details: Q9NR97
Human Recombinant Protein Products:
Gene Ontology (GO): 5/6 cellular component terms (GO ID links to tree view) (see all 6): About this table
TLR8 for ontologies About GeneDecksing
TLR8 Antibody Products:
Assay Products for TLR8: |
Protein
Domains /
Families
for TLR8 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
TLR8 for domains About GeneDecksing
5 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q9NR97ProtoNet protein and cluster: Q9NR97 2 Blocks protein families: IPB000157 TIR domain IPB000483 Cysteine-rich flanking region
UniProtKB/Swiss-Prot: TLR8_HUMAN, Q9NR97Similarity: Belongs to the Toll-like receptor familySimilarity: Contains 23 LRR (leucine-rich) repeatsSimilarity: Contains 1 LRRCT domainSimilarity: Contains 1 TIR domain |
Function
for TLR8 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: TLR8_HUMAN, Q9NR97Function: Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune responseagainst pathogens through recognition of molecular patterns specific to microorganisms. Acts via MYD88 and TRAF6,leading to NF-kappa-B activation, cytokine secretion and the inflammatory response
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TLR8 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TLR8
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: TLR8 (NM_138636) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for TLR8 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TLR8 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TLR8 |
Gene Ontology (GO): 5 molecular function terms (GO ID links to tree view): About this table
TLR8 for ontologies About GeneDecksing
1 GenomeRNAi human phenotype for TLR8:
Animal Models:
4 MGI mutant phenotypes (inferred from 2 alleles ) (MGI details for Tlr8):
TLR8 for phenotypes About GeneDecksing
|
Pathways & Interactions
for TLR8 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways - 5/16 super-pathways (see all 16) About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | TRAF6 Mediated Induction of proinflammatory cytokines | | | 2 | Toll-like receptor signaling pathway | | | 3 | Endosomal TLRs pass through the Golgi | | | 4 | Immune System | | | 5 | Immune response Toll-like receptor (TLR) ligands and common TLR signaling pathway leading to cell proinflammatory response | |
Pathway sources
See GeneCards unified pathways
Show all pathways
1 EMD Millipore Pathway for TLR8
4  R&D Systems Pathways for TLR8
5/8 Downloadable PowerPoint Slides of QIAGEN Pathway Central Maps for TLR8 (see all 8)
1 
Cell Signaling Technology (CST) Pathway for TLR8
1  Tocris Bioscience Pathway for TLR8
1  GeneGo (Thomson Reuters) Pathway for TLR8
1  BioSystems Pathway for TLR8
5/11 
Reactome Pathways for TLR8 (see all 11)
1 
Kegg Pathway (Kegg details for TLR8):
TLR8 for pathways About GeneDecksing
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for TLR8
STRING Interaction
Network Preview (showing 5 interactants - click image to see 11)
5/13 Interacting proteins for TLR8 (Q9NR973 ENSP000002180324) via UniProtKB, MINT, STRING, and/or I2D (see all 13)About this table
Gene Ontology (GO): 5/13 biological process terms (GO ID links to tree view) (see all 13): About this table
TLR8 for ontologies About GeneDecksing
|
Drugs & Compounds
for TLR8 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
TLR8 for compounds About GeneDecksing
 |
Enzo Life Sciences drugs & compounds for TLR8 |
Browse Tocris compounds for TLR8
1 DrugBank Compound for TLR8 About this table
4 Novoseek chemical compound relationships for TLR8 gene About this table
Search CenterWatch for drugs/clinical trials and news about TLR8
|
Transcripts
for TLR8 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for TLR8 gene (2 alternative transcripts): NM_138636.4 NM_016610.2 Unigene Cluster for TLR8: Toll-like receptor 8 Hs.660543 [show with all ESTs]Unigene Representative Sequence: NM_1386362 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000218032(uc004cve.3 uc004cvd.3) ENST00000311912
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TLR8 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TLR8
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: TLR8 (NM_138636) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for TLR8 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TLR8 |
Additional cDNA sequence: AB445666.1 AF245703.1 AF246971.1 AK075117.1 AK297024.1 AK307562.1 AK314240.1 AY358296.1 BC101074.1 BC101075.2 BC101076.2 BC101077.1 2 DOTS entries: DT.109879 DT.91707993 24/28 AceView cDNA sequences (see all 28): NM_016610 AA922616 NM_138636 AA740964 AL544223 AI261982 AK075117 BX106790 AI424196 BQ448547 BE857344 AY358296 AF245703 AA568781 CR596887 CD365421 AF246971 AW872374 AI890649 C01399 CA310384 AA707766 AA042875 BX391663
GeneLoc Exon Structure
3 Alternative Splicing Database (ASD) splice patterns (SP) for TLR8 About this scheme
| ExUns: | 1a | · | 1b | ^ | 2a | · | 2b | · | 2c | ^ | 3a | · | 3b |
|---|
|
| SP1: | | | | | - | | | | - | | | | | | |
| SP2: | | | | | - | | - | | - | | | | | | |
| SP3: | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for TLR8
|
Expression
for TLR8 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| TLR8 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GTTATATTAT
About this image
See TLR8 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for TLR8
SOURCE GeneReport for Unigene cluster: Hs.660543
UniProtKB/Swiss-Prot: TLR8_HUMAN, Q9NR97Tissue specificity: Detected in brain, heart, lung, liver, placenta, in monocytes, and at lower levels in CD11c+immature dendritic cells
SABiosciences Expression via Pathway-Focused PCR Arrays including TLR8: | Innate & Adaptive Immune Responses in human mouse rat | | Antiviral Response in human mouse rat | | Toll-Like Receptor Signaling Pathway in human mouse rat | | Type I Interferon Response in human mouse rat | | Inflammatory Response & Autoimmunity 384HT in human mouse rat |
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for TLR8
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat TLR8 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TLR8 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TLR8 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TLR8 |
Orthologs
for TLR8 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for TLR8 gene from 2/11 species (see all 11) About this table
ENSEMBL Gene Tree for TLR8 (if available)
TreeFam Gene Tree for TLR8 (if available) |
Paralogs
for TLR8 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for TLR8 gene
- CD1802 ENSG000001733662 TLR72 TLR12 TLR92 TLR52 TLR102 LRRC332
- TLR42 TLR62 LRRC322 TLR32 TLR22
2 SIMAP similar genes for TLR8 using alignment to 5 protein entries: TLR8_HUMAN (see all proteins):TLR7 TLR9
TLR8 for paralogs About GeneDecksing
|
Genomic Variants
for TLR8 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr X pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for TLR8 (12924739 - 12941288 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for TLR8: --
Human Gene Mutation Database (HGMD): TLR8
Locus Specific Mutation Databases (LSDB): TLR8
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing TLR8 |
|
Disorders
/ Diseases
for TLR8 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
TLR8 for disorders About GeneDecksing
OMIM gene information: 300366
OMIM disorders: --
20/44  diseases for TLR8 (see all 44): About MalaCardsdengue hemorrhagic fever hemorrhagic fever bronchiolitis obliterans systemic lupus erythematosus
lupus erythematosus inflammatory bowel disease bronchiolitis dilated cardiomyopathy
acute myeloid leukemia fanconi's anemia antiphospholipid syndrome myeloid leukemia
viral hepatitis agammaglobulinemia was-related disorders celiac disease
pandas keratitis rheumatoid arthritis pulmonary tuberculosis
6 Novoseek disease relationships for TLR8 gene About this table
Human Genome Epidemiology (HuGE) Navigator: TLR8 (28 documents)
Export disorders for TLR8 gene to outside databases
|
Publications
for TLR8 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for TLR8 gene, integrated from 9 sources (see all 187):
(articles sorted by number of sources associating them with TLR8) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Three novel mammalian Toll-like receptors: gene structure, expression, and evolution. (PubMed id 11022119)1, 2, 3, 9 Du X.... Beutler B. (2000)
- Natural selection in the TLR-related genes in the course of primate evolution. (PubMed id 18810425)1, 2 Nakajima T....Kimura A. (2008)
- Signaling by Toll-like receptors 8 and 9 requires Bruton's tyrosine kinase. (PubMed id 17932028)1, 2 Doyle S.L....O'Neill L.A. (2007)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)1, 2 Clark H.F.... Gray A.M. (2003)
- Cloning and characterization of a sub-family of human Toll-like receptors: hTLR7, hTLR8 and hTLR9. (PubMed id 11022120)1, 2 Chuang T.-H. and Ulevitch R.J. (2000)
- The covalent modification and regulation of TLR8 in HEK-293 cells stimulated with imidazoquinoline agonists. (PubMed id 17868034)1, 9 Rajagopal R....Wightman P.D. (2008)
- TLR7 and TLR8 agonists trigger different signaling pathways for human dendritic cell maturation. (PubMed id 19164127)1, 9 LarangAc A....Kerdine-RAPmer S. (2009)
- Porcine TLR8 and TLR7 are both activated by a selective TLR7 ligand, imiquimod. (PubMed id 18439678)7, 9 Zhu J....Mutwiri G.K. (2008)
- A five-amino-acid motif in the undefined region of th e TLR8 ectodomain is required for species-specific ligand recognition. (PubMed id 20004021)1, 9 Liu J....Chuang T.H. (2010)
|
External Searches for TLR8 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing TLR8 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing TLR8 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing TLR8 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for TLR8 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for TLR8 gene:
Search GeneIP for patents involving TLR8
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for TLR8 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | OriGene Antibodies for TLR8 | | OriGene shRNA RFP for TLR8 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for TLR8 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for TLR8 | | | OriGene Protein Over-expression Lysate for TLR8 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for TLR8 | | Browse 3'-UTR reporter clones for miRNA target validation | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TLR8 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TLR8 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for TLR8 | | OriGene Custom Protein Services for TLR8 | | | OriGene Custom Immunoassay Development | | |
| |
 |
 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat TLR8 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing TLR8 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TLR8 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TLR8 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TLR8 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TLR8 |
| |
 |  |  |  | |
| | Antibodies & Assays for TLR8 |
| | | | Search Tocris compounds for TLR8 |
| |  |  |  |  | | | | |
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 | | | TLR8 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TLR8 |
|  |  |  | | | | ThermoFisher Antibody for TLR8 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TLR8 |
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