TLR6 Gene
protein-coding GIFtS: 64
GCID: GC04M038828
|
|
toll-like receptor 6
| |
Aliases
for TLR6 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Toll-Like Receptor 61 2 | | CD2861 2 | | CD286 Antigen3 |
Export aliases for TLR6 gene to outside databasesPrevious GC identifers: GC04P039066 GC04M038992 GC04M038663 GC04M038725 GC04M038650 GC04M038504 GC04M038149 |
Summaries
for TLR6 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for TLR6:
The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role inpathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and sharestructural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that areexpressed on infectious agents, and mediate the production of cytokines necessary for the development of effectiveimmunity. The various TLRs exhibit different patterns of expression. This receptor functionally interacts withtoll-like receptor 2 to mediate cellular response to bacterial lipoproteins. A Ser249Pro polymorphism in theextracellular domain of the encoded protein may be associated with an increased of asthma is somepopulations.(provided by RefSeq, Jan 2011)
UniProtKB/Swiss-Prot: TLR6_HUMAN, Q9Y2C9Function: Participates in the innate immune response to Gram-positive bacteria and fungi. Specifically recognizesdiacylated and, to a lesser extent, triacylated lipopeptides. Acts via MYD88 and TRAF6, leading to NF-kappa-Bactivation, cytokine secretion and the inflammatory response. Recognizes mycoplasmal macrophage-activatinglipopeptide-2kD (MALP-2), soluble tuberculosis factor (STF), phenol-soluble modulin (PSM) and B.burgdorferi outersurface protein A lipoprotein (OspA-L) cooperatively with TLR2
 summary
for TLR6: Toll-like receptors (TLRs) are single transmembrane cell-surface receptors, which have a key role in the
innate immune system. TLRs generally exist as homodimers (although TLR2-TLR6 heterodimers have been
reported) and are found on immune cells such as macrophages, B lymphocytes and mast cells. Toll-like
receptors are activated by molecules associated with biological threat and are highly specific towards
evolutionary conserved entities on microbes, such as bacterial cell-surface lipopolysaccharides, flagella
and unmethylated CpG islands. It has been suggested that some toll-like receptors may have endogenous
ligands, such as Hsp60 and fibrinogen, and this has promoted speculation that endogenous toll-like receptor
activators may have a pathological role in autoimmune disease. Activation of toll-like receptors initiates
downstream signaling cascades, initially via the adapter molecules MyD88, Trap, Trif and Tram, which
converge on the PI 3-K and NF-kappaB pathways and regulate intracellular kinases and gene expression. This
can stimulate an inflammatory and/or antigen-specific immune response. The signaling cascade coupled to
toll-like receptor activation is very similar to that of interleukin-1 receptor (IL-1R) activation.
Gene Wiki entry for TLR6
|
Genomic Views
for TLR6 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000004.11 NC_018915.1 NT_016297.16
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the TLR6 gene promoter:
E2F-4 E2F-3a ATF-2 E2F-2 CREB E2F E2F-1 deltaCREB c-Jun
Other transcription factors
Search SABiosciences Chromatin IP Primers for TLR6
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TLR6 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 4p14 Ensembl cytogenetic band: 4p14 HGNC cytogenetic band: 4p16.1TLR6 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 4 GeneLoc Exon Structure GeneLoc location for GC04M038828: view genomic region
(about GC identifiers)
Start:
|
38,825,325 bp from pter |
End:
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38,858,438 bp from pter |
Size:
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33,114 bases |
Orientation:
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minus strand |
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Proteins
for TLR6 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: TLR6_HUMAN, Q9Y2C9 (See
protein sequence)Recommended Name: Toll-like receptor 6 precursor Size: 796 amino acids; 91880 Da
Subunit: Binds MYD88 via their respective TIR domains. Heterodimer with TLR2 via their respective extracellular domains(By similarity)
Subcellular location: Cell membrane; Single-pass type I membrane protein (By similarity). Cytoplasmic vesicle,phagosome membrane; Single-pass type I membrane protein (By similarity)
Secondary accessions: B3Y640 B6CH35 B6RFS4 B6RFS5Explore the universe of human proteins at neXtProt for TLR6: NX_Q9Y2C9
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9Y2C9
TLR6 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_006059.2
ENSEMBL proteins: ENSP00000371376 ENSP00000424718 ENSP00000423326 ENSP00000389600 Reactome Protein details: Q9Y2C9
Human Recombinant Protein Products:
Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view): About this table
TLR6 for ontologies About GeneDecksing
TLR6 Antibody Products:
Assay Products for TLR6: |
Protein
Domains /
Families
for TLR6 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
TLR6 for domains About GeneDecksing
5 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q9Y2C9ProtoNet protein and cluster: Q9Y2C9 3 Blocks protein families: IPB000157 TIR domain IPB000483 Cysteine-rich flanking region IPB001611 Leucine-rich repeat signature
UniProtKB/Swiss-Prot: TLR6_HUMAN, Q9Y2C9Similarity: Belongs to the Toll-like receptor familySimilarity: Contains 19 LRR (leucine-rich) repeatsSimilarity: Contains 1 LRRCT domainSimilarity: Contains 1 TIR domain |
Function
for TLR6 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: TLR6_HUMAN, Q9Y2C9Function: Participates in the innate immune response to Gram-positive bacteria and fungi. Specifically recognizesdiacylated and, to a lesser extent, triacylated lipopeptides. Acts via MYD88 and TRAF6, leading to NF-kappa-Bactivation, cytokine secretion and the inflammatory response. Recognizes mycoplasmal macrophage-activatinglipopeptide-2kD (MALP-2), soluble tuberculosis factor (STF), phenol-soluble modulin (PSM) and B.burgdorferi outersurface protein A lipoprotein (OspA-L) cooperatively with TLR2 Genatlas biochemistry entry for TLR6:Drosophila transmembrane receptor Toll homolog 6,predominantly expressed in spleen,thymus,ovary and lung
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TLR6 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TLR6
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
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Synthesis Service for TLR6 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TLR6 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TLR6 |
Gene Ontology (GO): 5 molecular function terms (GO ID links to tree view): About this table
TLR6 for ontologies About GeneDecksing
1 GenomeRNAi human phenotype for TLR6:
Animal Models:
Mouse knock-out Tlr6tm1Aki for TLR6
2 MGI mutant phenotypes (inferred from 5 alleles ) (MGI details for Tlr6):
TLR6 for phenotypes About GeneDecksing
|
Pathways & Interactions
for TLR6 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways - 5/15 super-pathways (see all 15) About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | TRAF6 Mediated Induction of proinflammatory cytokines | | | 2 | Toll-like receptor signaling pathway | | | 3 | Immune System | | | 4 | Immune response Toll-like receptor (TLR) ligands and common TLR signaling pathway leading to cell proinflammatory response | | | 5 | TRAF Pathway | |
Pathway sources
See GeneCards unified pathways
Show all pathways
1 EMD Millipore Pathway for TLR6
5  R&D Systems Pathways for TLR6
5/8 Downloadable PowerPoint Slides of QIAGEN Pathway Central Maps for TLR6 (see all 8)
1 Tocris Bioscience Pathway for TLR6
1  GeneGo (Thomson Reuters) Pathway for TLR6
1  BioSystems Pathway for TLR6
5/9 
Reactome Pathways for TLR6 (see all 9)
4 
Kegg Pathways (Kegg details for TLR6):
TLR6 for pathways About GeneDecksing
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for TLR6
STRING Interaction
Network Preview (showing 5 interactants - click image to see 11)
5/12 Interacting proteins for TLR6 (Q9Y2C93 ENSP000003713764) via UniProtKB, MINT, STRING, and/or I2D (see all 12)About this table
Gene Ontology (GO): 5/18 biological process terms (GO ID links to tree view) (see all 18): About this table
TLR6 for ontologies About GeneDecksing
|
Drugs & Compounds
for TLR6 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
TLR6 for compounds About GeneDecksing
Compounds for TLR6 available from Tocris Bioscience About this table
| Compound | Action |
CAS
# |
|---|
| GIT 27 | Immunomodulator; reduces production of pro-inflammatory cytokines | [6501-72-0] |
4 Novoseek chemical compound relationships for TLR6 gene About this table
Search CenterWatch for drugs/clinical trials and news about TLR6
|
Transcripts
for TLR6 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for TLR6 gene: NM_006068.4 Unigene Clusters for TLR6: Toll-like receptor 6 Hs.575090 [show with all ESTs], Hs.743572 [show with all ESTs]Unigene Representative Sequences: NM_006068, AB4456524 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000381950(uc003gtm.3) ENST00000508254 ENST00000514655 ENST00000436693(uc010ifg.2)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TLR6 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TLR6
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: TLR6 (NM_006068) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for TLR6 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TLR6 |
Additional cDNA sequence: AB445652.1 5 DOTS entries: DT.40189829 DT.439547 DT.91841289 DT.101960681 DT.40289093 13 AceView cDNA sequences: NM_006068 AA810462 AB020807 AA381849 CA310973 CF136926 BI031573 AA831782 BQ337481 BF170087 BE814766 AI184710 BI031578
GeneLoc Exon Structure
|
Expression
for TLR6 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| TLR6 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --
About this image
See TLR6 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for TLR6
SOURCE GeneReport for Unigene clusters: Hs.575090 Hs.743572
UniProtKB/Swiss-Prot: TLR6_HUMAN, Q9Y2C9Tissue specificity: Detected in monocytes, CD11c+ immature dendritic cells, plasmacytoid pre-dendritic cells and dermalmicrovessel endothelial cells
SABiosciences Expression via Pathway-Focused PCR Arrays including TLR6 (see all 9):
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for TLR6
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat TLR6 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TLR6 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TLR6 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TLR6 |
Orthologs
for TLR6 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for TLR6 gene from 4/14 species (see all 14) About this table
ENSEMBL Gene Tree for TLR6 (if available)
TreeFam Gene Tree for TLR6 (if available) |
Paralogs
for TLR6 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for TLR6 gene
- CD1802 ENSG000001733662 TLR72 TLR12 TLR92 TLR52 TLR102 LRRC332
- TLR42 TLR82 LRRC322 TLR32 TLR22
3 SIMAP similar genes for TLR6 using alignment to 17 protein entries: TLR6_HUMAN (see all proteins):TLR1 TLR10 TLR2
TLR6 for paralogs About GeneDecksing
|
Genomic Variants
for TLR6 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 4 variations for TLR6
3 CNVs: 9472 80259 92051
1 Indel: 92052
Human Gene Mutation Database (HGMD): TLR6
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing TLR6 |
|
Disorders
/ Diseases
for TLR6 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
TLR6 for disorders About GeneDecksing
OMIM gene information: 605403
OMIM disorders: --
20/55  diseases for TLR6 (see all 55): About MalaCardsasthma non-hodgkin lymphoma invasive aspergillosis oral cavity cancer
chronic obstructive pulmonary disease bronchiolitis obliterans aspergillosis hodgkin's lymphoma
inflammatory bowel disease atopic dermatitis bronchiolitis chronic lymphocytic leukemia
lyme disease lymphocytic leukemia filariasis behcet's disease
pulmonary disease urethritis chagas disease multiple myeloma
4 Novoseek disease relationships for TLR6 gene About this table
| Disease |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| inflammation |
40.2 |
4 |
19019962 (1), 19117515 (1), 18424724 (1), 18159247 (1) |
| necrosis |
14.9 |
5 |
19621822 (1), 19019963 (1), 16960116 (1), 17714490 (1) (see all 5) |
| asthma |
12.1 |
5 |
15266299 (1), 18547625 (1), 16629799 (1), 16505608 (1) |
| tumors |
0 |
4 |
19621822 (1), 19019963 (1), 16960116 (1), 14585198 (1) |
Genetic Association Database (GAD): TLR6
Human Genome Epidemiology (HuGE) Navigator: TLR6 (57 documents)
Export disorders for TLR6 gene to outside databases
|
Publications
for TLR6 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for TLR6 gene, integrated from 9 sources (see all 199):
(articles sorted by number of sources associating them with TLR6) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- TLR6: a novel member of an expanding Toll-like receptor family. (PubMed id 10231569)1, 2, 3, 9 Takeuchi O.... Akira S. (1999)
- Toll-like receptor 6 gene (TLR6): single-nucleotide polymorphism frequencies and preliminary association with the diagnosis of asthma. (PubMed id 15266299)1, 4, 9 Tantisira K....Weiss S.T. (2004)
- Cooperation of Toll-like receptor 2 and 6 for cellular activation by soluble tuberculosis factor and Borrelia burgdorferi outer surface protein A lipoprotein: role of Toll-interacting protein and IL-1 receptor signaling molecules in Toll-like receptor 2 signaling. (PubMed id 11441107)1, 2, 9 Bulut Y.... Arditi M. (2001)
- Evaluation of the toll-like receptor 6 Ser249Pro polymorphism in patients with asthma, atopic dermatitis and chronic obstructive pulmonary disease. (PubMed id 16188043)1, 4, 9 Hoffjan S....Epplen J.T. (2005)
- Toll-like receptor-1, -2, and -6 polymorphisms influence disease extension in inflammatory bowel diseases. (PubMed id 16374251)1, 4, 9 Pierik M....Vermeire S. (2006)
- Natural selection in the TLR-related genes in the course of primate evolution. (PubMed id 18810425)1, 2 Nakajima T....Kimura A. (2008)
- Heterozygous Arg753Gln polymorphism of human TLR-2 impairs immune activation by Borrelia burgdorferi and protects from late stage Lyme disease. (PubMed id 16081826)1, 4 Schroder N.W....Schumann R.R. (2005)
- Sequence variants in Toll-like receptor gene cluster (TLR6-TLR1-TLR10) and prostate cancer risk. (PubMed id 15812078)1, 4 Sun J....Gronberg H. (2005)
- Surface-expressed TLR6 participates in the recognition of diacylated lipopeptide and peptidoglycan in human cells. (PubMed id 15661917)1, 9 Nakao Y....Matsumoto M. (2005)
- Hypoxia inducible factor (HIF)-1 coordinates induction of Toll-like receptors TLR2 and TLR6 during hypoxia. (PubMed id 18159247)1, 9 Kuhlicke J....Eltzschig H.K. (2007)
|
External Searches for TLR6 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing TLR6 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing TLR6 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing TLR6 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for TLR6 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for TLR6 gene:
Search GeneIP for patents involving TLR6
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for TLR6 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | OriGene Antibodies for TLR6 | | OriGene shRNA RFP for TLR6 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for TLR6 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for TLR6 | | | OriGene Protein Over-expression Lysate for TLR6 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for TLR6 | | OriGene 3'-UTR Clone for TLR6 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TLR6 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TLR6 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for TLR6 | | OriGene Custom Protein Services for TLR6 | | | OriGene Custom Immunoassay Development | | |
| |
 |
 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat TLR6 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing TLR6 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TLR6 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TLR6 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TLR6 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TLR6 |
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 |  |  |  | |
| | | | Tocris compounds for TLR6 |
| |  |  |  |  | | | | |
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 |
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 | | | TLR6 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TLR6 |
|  |  |  | | | | ThermoFisher Antibody for TLR6 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TLR6 |
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