TLN2 Gene
protein-coding GIFtS : 57
GCID: GC15 P062682
talin 2
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Aliasesfor TLN2 gene
(According to
1 HGNC ,
2 Entrez Gene ,
3 UniProtKB/Swiss-Prot ,
4 UniProtKB/TrEMBL , 5 OMIM , 6 GeneLoc ,
7 Ensembl ,
8 DME ,
9 miRBase ,
and/or 10 fRNAdb )About This Section Aliases Talin 2 1 2 KIAA03201 3 5 ILWEQ1 2 Talin-21
Export aliases for TLN2 gene to outside databases Previous GC identifers: GC15P058780 GC15P055987 GC15P060518 GC15P060655 GC15P060726 GC15P062939 GC15P039762
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Summariesfor TLN2 gene (According to Entrez Gene ,
Tocris Bioscience ,
Wikipedia's
Gene Wiki ,
PharmGKB ,
UniProtKB/Swiss-Prot ,
and/or
UniProtKB/TrEMBL )
About This Section Entrez Gene summary for TLN2 : This gene encodes a protein related to talin 1, a cytoskeletal protein that plays a significant role in the assembly of actin filaments and in spreading and migration of various cell types, including fibroblasts and osteoclasts. This protein has a different pattern of expression compared to talin 1 but, like talin 1, is thought to associate with unique transmembrane receptors to form novel linkages between extracellular matrices and the actin cytoskeleton. (provided by RefSeq, Jul 2008) UniProtKB/Swiss-Prot: TLN2_HUMAN, Q9Y4G6 Function : As a major component of focal adhesion plaques that links integrin to the actin cytoskeleton, may play animportant role in cell adhesion. Recruits PIP5K1C to focal adhesion plaques and strongly activates its kinase activity (By similarity)
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Genomic Viewsfor TLN2 gene
(According to
GeneLoc and/or
HGNC , and/or
Entrez Gene (NCBI build 37) ,
and/or miRBase ,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69) ,
Regulatory elements and Epigenetics data according to
QIAGEN ,
SABiosciences , and/or
SwitchGear Genomics )About This Section RefSeq DNA sequence: NC_000015.9 NC_018926.1 NT_010194.17 Regulatory elements: SABiosciences Regulatory transcription factor binding sites in the TLN2 gene promoter: TBP RP58 AML1a CHOP-10 AREB6 S8 POU2F1 POU2F1a SEF-1 (1) Hlf Other transcription factors Search SABiosciences Chromatin IP Primers for TLN2 Epigenetics: QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TLN2
Genomic Location: Genomic View : UCSC Golden Path with GeneCards custom track Entrez Gene cytogenetic band: 15q15-q21 Ensembl cytogenetic band: 15q22.2 HGNC cytogenetic band: 15q15-q21 TLN2 Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different) GeneLoc information about chromosome 15 GeneLoc Exon Structure
GeneLoc location for GC15P062682: view genomic region
(about GC identifiers )
Start:
62,682,725 bp from pter
End:
63,136,830 bp from pter
Size:
454,106 bases
Orientation:
plus strand
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Proteinsfor TLN2 gene
(According to
1 UniProtKB ,
HORDE ,
neXtProt ,
Ensembl ,
and/or Reactome ,
Modification sites according to 2 PhosphoSitePlus ,
Specific Peptides from DME ,
Protein expression images according to data from SPIRE MOPED and PaxDb ,
RefSeq according to NCBI ,
PDB rendering according to OCA and/or Proteopedia ,
Recombinant Proteins
from
EMD Millipore ,
R&D Systems ,
GenScript ,
Enzo Life Sciences ,
OriGene ,
Novus Biologicals ,
Sino Biological ,
ProSpec , and/or
Uscn ,
Biochemical Assays by
EMD Millipore ,
R&D Systems ,
OriGene ,
GenScript ,
Cell Signaling Technology ,
Enzo Life Sciences , and/or
Uscn ,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene ,
Antibodies by
EMD Millipore ,
R&D Systems ,
GenScript ,
Cell Signaling Technology ,
OriGene ,
Novus Biologicals ,
Thermo Fisher Scientific ,
Abcam , and/or
Uscn )
About This Section UniProtKB/Swiss-Prot: TLN2_HUMAN, Q9Y4G6 (See
protein sequence )Recommended Name: Talin-2 Size : 2542 amino acids; 271613 Da
Subunit : Interacts directly with PIP5K1C
Subcellular location : Cell junction, focal adhesion. Cell junction, synapse. Cell membrane; Peripheral membraneprotein; Cytoplasmic side. Cytoplasm, cytoskeleton. Note=Focal adhesion plaques and synapses
Secondary accessions : A6NLB8Explore the universe of human proteins at neXtProt for TLN2: NX_Q9Y4G6 Post-translational modifications:
View modification sites using PhosphoSitePlus 2 View neXtProt modification sites for NX_Q9Y4G6 TLN2 Protein expression data from MOPED and PaxDb : About this image
REFSEQ proteins: NP_055874.2 ENSEMBL proteins: ENSP00000453508 ENSP00000453730 ENSP00000453812 ENSP00000303476 Human Recombinant Protein Products: Gene Ontology (GO): 5/8 cellular component terms (GO ID links to tree view) (see all 8 ): About this table
TLN2 for ontologies About GeneDecksing TLN2 Antibody Products: Assay Products for TLN2:
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Protein
Domains / Familiesfor TLN2 gene (According to InterPro , ProtoNet ,
UniProtKB , and/or BLOCKS ,
Sets of similar genes according to GeneDecks )
About This Section
TLN2 for domains About GeneDecksing 5/13 InterPro domains/families (see all 13 ):
Graphical View of Domain Structure for InterPro Entry Q9Y4G6 ProtoNet protein and cluster: Q9Y4G6
2 Blocks protein families : IPB000299 Band 4.1 domain IPB002558 I/LWEQ domain UniProtKB/Swiss-Prot: TLN2_HUMAN, Q9Y4G6 Similarity : Contains 1 FERM domainSimilarity : Contains 1 I/LWEQ domain
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Functionfor TLN2 gene
(According to 1 UniProtKB ,
Genatlas ,
LifeMap Discovery™ ,
IUBMB , and/or
2 DME ,
Human phenotypes from GenomeRNAi ,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences ,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene ,
RNAi from
EMD Millipore ,
siRNAs from
OriGene ,
QIAGEN ,
microRNA from QIAGEN ,
Gene Editing from DNA2.0 ,
Clones from EMD Millipore ,
OriGene ,
SwitchGear Genomics ,
GenScript ,
Sino Biological ,
DNA2.0 ,
and Vector BioLabs ,
Cell Lines from GenScript ,
LifeMap BioReagents ,
In Situ Hybridization Assays from Advanced Cell Diagnostics ,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene .)
About This Section Function Summary: UniProtKB/Swiss-Prot: TLN2_HUMAN, Q9Y4G6 Function : As a major component of focal adhesion plaques that links integrin to the actin cytoskeleton, may play animportant role in cell adhesion. Recruits PIP5K1C to focal adhesion plaques and strongly activates its kinase activity (By similarity)
Clone Products: Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human , mouse , rat for TLN2 (see all 3 ) OriGene untagged cDNA clones in CMV expression vector in human , mouse , rat for TLN2OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling GenScript: all cDNA clones in your preferred vector: TLN2 (NM_015059 ) Browse Sino Biological Human cDNA Clones DNA2.0 Custom Codon Optimized Gene
Synthesis Service for TLN2 Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat TLN2
In Situ Assay Products: Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TLN2
Gene Ontology (GO): 5 molecular function terms (GO ID links to tree view) : About this table
TLN2 for ontologies About GeneDecksing Animal Models: Mouse knock-outs for TLN2: Tln2 tm1.1Crit Tln2 tm2Crit 5 MGI mutant phenotypes (inferred from 5 alleles ) (MGI details for Tln2) :
TLN2 for phenotypes About GeneDecksing
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Pathways & Interactionsfor TLN2 gene
(Pathways according to
EMD Millipore ,
R&D Systems ,
Cell Signaling Technology ,
KEGG ,
PharmGKB ,
BioSystems ,
Reactome ,
Tocris Bioscience ,
GeneGo (Thomson Reuters) ,
QIAGEN ,
and/or UniProtKB ,
Sets of similar genes according to GeneDecks ,
Interaction Networks according to
SABiosciences ,
and/or STRING ,
Interactions according to 1 UniProtKB ,
2 MINT ,
3 I2D , and/or
4 STRING ,
with links to IntAct and
Ensembl ,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene) .
About This Section Unified GeneCards pathways  - 5/10 super-pathways (see all 10 ) About this table See pathways by source Super-pathway contained gene-specific pathways 1 Cell adhesion_Integrin-mediated cell adhesion and migration 2 Integrin Pathway 3 Cell adhesion_Integrin inside-out signaling 4 Development_Endothelin-1/EDNRA transactivation of EGFR 5 Focal Adhesion
Pathway sources See GeneCards unified pathways Show all pathways 5 EMD Millipore Pathways for TLN2 5/6 Downloadable PowerPoint Slides of QIAGEN Pathway Central Maps for TLN2 (see all 6 )5/6 GeneGo (Thomson Reuters) Pathways for TLN2 (see all 6 )1
Kegg Pathway (Kegg details for TLN2) :
TLN2 for pathways About GeneDecksing Interactions: Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for TLN2 STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)5/556 Interacting proteins for TLN2 (Q9Y4G6 2 , 3 ENSP00000303476 4 ) via UniProtKB, MINT, STRING , and/or I2D (see all 556 )About this table Gene Ontology (GO): 3 biological process terms (GO ID links to tree view) : About this table
TLN2 for ontologies About GeneDecksing
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Drugs & Compoundsfor TLN2 gene (Chemical Compounds according to UniProtKB , Enzo Life Sciences ,
EMD Millipore , Tocris Bioscience
HMDB ,
BitterDB , and/or
Novoseek , and Drugs according to
DrugBank ,
Enzo Life Sciences , and/or
PharmGKB , with drugs/clinical trials/news
search links to CenterWatch )
About This Section Browse Tocris compounds for TLN2 Search CenterWatch for drugs/clinical trials and news about TLN2
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Transcriptsfor TLN2 gene (Secondary structures according to
fRNAdb ,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank , RefSeq according to Entrez Gene ,
DOTS (version 10), and/or
AceView ,
transcript ids from Ensembl
with links to UCSC ,
exon structure from GeneLoc ,
alternative splicing isoforms according to ASD and/or
ECgene ,
RNAi Products from
EMD Millipore ,
siRNAs from
OriGene ,
QIAGEN ,
shRNA from
OriGene ,
microRNA from QIAGEN ,
Tagged/untagged cDNA clones from
OriGene ,
SwitchGear Genomics ,
GenScript ,
DNA2.0 ,
Vector BioLabs ,
Primers from
OriGene ,
SABiosciences , and/or
QIAGEN
)About This Section REFSEQ mRNAs for TLN2 gene: NM_015059.2 Unigene Clusters for TLN2:
Talin 2 Hs.569438 [show with all ESTs ] , Hs.610975 Unigene Representative Sequences: NM_015059 , AL122065 11 Ensembl transcripts including schematic representations, and UCSC links where relevant : ENST00000561322 ENST00000561197 ENST00000561311 ENST00000474847 ENST00000494733 ENST00000559908 ENST00000489129 ENST00000472902 (uc002ald.3 ) ENST00000467297 ENST00000559174 ENST00000306829 (uc002alb.4 uc002alc.4 uc010uic.2 )Clone Products: OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human , mouse , rat for TLN2 (see all 3 ) OriGene untagged cDNA clones in CMV expression vector in human , mouse , rat for TLN2OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling GenScript: all cDNA clones in your preferred vector: TLN2 (NM_015059 ) DNA2.0 Custom Codon Optimized Gene
Synthesis Service for TLN2 Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat TLN2
Additional cDNA sequence: AL122065.1
7 DOTS entries : DT.100754091 DT.455182
DT.95214510 DT.40229939 DT.121070150 DT.75107131 DT.431249 3 AceView cDNA sequences :
AL122065 AL042061 BF737572 GeneLoc Exon Structure 5/11 Alternative Splicing Database (ASD) splice patterns (SP) for TLN2 (see all 11 ) About this scheme ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6a · 6b ^ 7 ^ 8 ^ 9 ^ 10 ^ 11a · 11b ^ 12a · 12b ^ 13a · 13b ^ 14 ^ 15 ^ 16 ^ 17 ^ 18 ^ 19 ^ 20 ^ 21 ^ 22 ^ SP1 :                                                   -   SP2 :                                                     SP3 :                                                     SP4 :                                                     SP5 :                                                    
ExUns: 23 ^ 24 ^ 25a · 25b ^ 26a · 26b ^ 27 ^ 28 ^ 29 ^ 30 ^ 31 ^ 32 ^ 33 ^ 34 ^ 35 ^ 36 ^ 37 ^ 38 ^ 39 ^ 40a · 40b ^ 41 ^ 42 ^ 43 ^ 44 ^ 45 ^ SP1 :         -               -                   -             SP2 :                       -                   -             SP3 :                                                     SP4 :                                                     SP5 :                                                    
ExUns: 46 ^ 47 ^ 48 ^ 49a · 49b ^ 50a · 50b ^ 51a · 51b ^ 52a · 52b ^ 53a · 53b ^ 54a · 54b · 54c SP1 :               -       -             SP2 :               -       -             SP3 :                                 SP4 :                                 SP5 :               -                  
ECgene alternative splicing isoforms for TLN2
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Expression for TLN2 gene
(RNA expression data according to
H-InvDB ,
NONCODE ,
miRBase , and
RNAdb ,
Expression images according to data from
BioGPS ,
Illumina Human BodyMap , and
CGAP
SAGE ,
Sets of similar genes according to GeneDecks ,
in vivo and in vitro expression data from LifeMap Discovery™ ,
plus additional links to
Genevestigator , and/or
SOURCE , and/or
BioGPS , and/or
UniProtKB ,
PCR Arrays from
SABiosciences ,
Primers from
OriGene ,
SABiosciences , and/or
QIAGEN ,
In Situ Hybridization Assays from Advanced Cell Diagnostics )
About This Section TLN2 expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this image BioGPS CGAP TAG: AAAGGTTATT
About this image TLN2 expression in embryonic tissues and stem cells Expression by the Database of Embryonic development, Stem cell research, and
Regenerative medicine About this table Stem Cell Differentiation: 1 LifeMap Cell Name Category PureStem™ mesenchymal progenitor SM30 (Embryonic Progenitor Cell)Adipose, Bone, Cartilage Expression: Positive Negative
Selective markerExperimental details:
Curated
Microarrays
In-situ hybridization
See TLN2 Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for TLN2 SOURCE GeneReport for Unigene clusters: Hs.569438 Hs.610975 SABiosciences Expression via Pathway-Focused PCR Array including TLN2 : Primer Products: OriGene genome-wide validated SYBR primer pairs in human , mouse , rat for TLN2Browse OriGene validated miRNA SYBR primer pairs SABiosciences RT2 qPCR Primer Assay in human , mouse , rat TLN2 QIAGEN QuantiTect SYBR Green Assays in human , mouse , rat TLN2 QIAGEN QuantiFast Probe-based Assays in human , mouse , rat TLN2 In Situ Assay Products: Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TLN2
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Orthologsfor TLN2 gene
(Orthologs according to
1,2 HomoloGene (2 older version, for species not in 1 newer version),
3 euGenes ,
4 SGD
,
5 MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase ,
and/or
6 Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam )
About This Section
This gene was present in the common ancestor of animals.
Orthologs for TLN2 gene from 6/22 species (see all 22 ) About this table
Organism
Taxonomic classification
Gene
Description
Human Similarity
Orthology Type
Details
chicken (Gallus gallus)
Aves
TLN21
talin 2
81.39(n) 96.14(a)
 
415374 XM_003641877.1 XP_003641925.1
lizard (Anolis carolinensis)
Reptilia
TLN26
--
94(a)
1 ↔ 1
GL344433.1(312-29691)
African clawed frog (Xenopus laevis)
Amphibia
Xl.20372
Xenopus laevis transcribed sequence with moderate similarity to protein spQ9Y490 (H.sapiens) TALI_HUMAN TALIN less
76.53(n)
 
BX845985.1
zebrafish (Danio rerio)
Actinopterygii
zgc636132
similar to talin 2
79.93(n)
 
394168 BC055166.1
fruit fly (Drosophila melanogaster)
Insecta
rhea1
CG6831-PA
54.12(n) 48.5(a)
 
38978 NM_139981.3 NP_648238.1
worm (Caenorhabditis elegans)
Secernentea
Y71G12B.111
Protein Y71G12B.11
47.49(n) 39.68(a)
 
171736 NM_058485.4 NP_490886.2
ENSEMBL Gene Tree for TLN2 (if available)TreeFam Gene Tree for TLN2 (if available)
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Paralogsfor TLN2 gene (Paralogs according to
1 HomoloGene , 2 Ensembl , and 3 SIMAP , Pseudogenes according to 4 Pseudogene.org Build 68)About This Section Paralogs for TLN2 gene HIP1 2 HIP1R 2 MESDC1 2 TLN1 2 1 SIMAP similar gene for TLN2 using alignment to 4 protein entries: TLN2_HUMAN (see all proteins ):TLN1
TLN2 for paralogs About GeneDecksing 1 Pseudogenes.org Pseudogene for TLN2 PGOHUM00000246004
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Genomic Variantsfor TLN2 gene (SNPs/Variants according to the
1 NCBI SNP Database ,
2 Ensembl ,
3 PupaSUITE ,
UniProtKB , and
DNA2.0 ,
Linkage Disequilibrium by HapMap ,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants , Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB) , Blood group antigen gene mutations by BGMUT ,
Resequencing Primers from QIAGEN ,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences )
About This Section
Genomic Data Transcription Related Data Allele Frequencies SNP ID Valid Clinical significance Chr 15 pos Sequence # AA Chg Type More # Allele freq Pop Total sample More
HapMap Linkage Disequilibrium report for TLN2 (62682725 - 62932725 bp, first 250kb of TLN2)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV): 4 variations for TLN2 4 Indels : 76980 45354 41738 87705
SABiosciences Cancer Mutation PCR Assays
QIAGEN SeqTarget long-range PCR primers in human , mouse , rat for resequencing TLN2
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Disorders
/ Diseasesfor TLN2 gene
(in which this Gene is Involved, According to MalaCards ,
OMIM, UniProtKB ,
the University of Copenhagen DISEASES
database ,
Genatlas , GeneTests ,
GAD ,
HuGE Navigator ,
and/or TGDB .)
About This Section
TLN2 for disorders About GeneDecksing
OMIM gene information: 607349
OMIM disorders : --3 diseases for TLN2 : About MalaCards temporal lobe epilepsy breast carcinoma carcinoma Human Genome Epidemiology (HuGE) Navigator: TLN2 (1 document)Export disorders for TLN2 gene to outside databases
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Publicationsfor TLN2 gene (in
PubMed .
Associations of this gene to articles via
1 Entrez Gene ,
2 UniProtKB/Swiss-Prot ,
3 HGNC ,
4 GAD ,
5 PharmGKB ,
6 HMDB ,
7 DrugBank ,
8 UniProtKB/TrEMBL ,
9 Novoseek , and/or
10 fRNAdb )
About This Section PubMed articles for TLN2 gene, integrated from 9 sources (see all 31 ): (articles sorted by number of sources associating them with TLN2) Utopia : connect your pdf to the dynamic world of online information
Analysis of the mammalian talin2 gene TLN2. (PubMed id 11527381) 1 , 2 , 3 Monkley S.J....Critchley D.R. (2001) Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro. (PubMed id 9205841) 1 , 2 , 3 Nagase T.... Ohara O. (1997) A probability-based approach for high-throughput protein phosphorylation analysis and site localization. (PubMed id 16964243) 1 , 2 Beausoleil S.A.... Gygi S.P. (2006) Recruitment and regulation of phosphatidylinositol phosphate kinase type 1 gamma by the FERM domain of talin. (PubMed id 12422219) 1 , 2 Di Paolo G.... De Camilli P. (2002) Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones. (PubMed id 12168954) 1 , 2 Nakajima D.... Nagase T. (2002) Proteomic analysis of cerebrospinal fluid from patients with idiopathic temporal lobe epilepsy. (PubMed id 19109932) 1 , 9 Xiao F....Wang X.F. (2009) Talin2 is induced during striated muscle differentiation and is targeted to stable adhesion complexes in mature muscle. (PubMed id 17183545) 1 , 9 Senetar M.A....McCann R.O. (2007) A census of human soluble protein complexes. (PubMed id 22939629) 1 Havugimana P.C....Emili A. (2012) b2 integrin adhesion complexes maintain the integrity of HIV-1 assembly compartments in primary macrophages. (PubMed id 22017400) 1 Pelchen-Matthews A....Marsh M. (2012) Full-length transcriptome analysis of human retina-derived cell lines ARPE-19 and Y79 using the vector-capping method. (PubMed id 21697133) 1 Oshikawa M.... Kato S. (2011)
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External Searches for TLN2 gene
(in PubMed ,
OMIM , and NCBI Bookshelf ) About This Section
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Genome Databases showing TLN2 gene
(According to
Entrez Gene ,
HGNC ,
AceView ,
euGenes ,
Ensembl ,
miRBase ,
ECgene ,
Kegg ,
and/or
H-InvDB )
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Other Databases showing TLN2 gene
(According to HUGE )
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Specialized Databases showing TLN2 gene (According to PharmGKB ,
ATLAS , HORDE , IMGT , LEIDEN , UniProtKB/Swiss-Prot , and/or UniProtKB/TrEMBL ,Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot )About This Section
Name Description
PharmGKB entry for TLN2 Pharmacogenomics, SNPs, Pathways
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About This Section Patent Information for TLN2 gene: Search GeneIP for patents involving TLN2 GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Productsfor TLN2 gene (Antibodies, recombinant proteins, and assays from EMD Millipore , R&D Systems , OriGene , QIAGEN , GenScript , Cell Signaling Technology , SABiosciences , Novus Biologicals , Sino Biological , Enzo Life Sciences , Abcam , ProSpec , Uscn , Thermo Fisher Scientific , Gene Editing from DNA2.0 , Clones from EMD Millipore , OriGene , GenScript , Sino Biological , DNA2.0 , SwitchGear Genomics , Vector BioLabs , Cell lines from GenScript and LifeMap BioReagents , PCR Arrays from SABiosciences , Drugs and/or compounds from EMD Millipore , Tocris Bioscience , and/or
Enzo Life Sciences ), In Situ Hybridization Assays from Advanced Cell Diagnostics About This Section
OriGene Antibodies for TLN2 OriGene shRNA RFP for TLN2 OriGene 29mer shRNA kits in GFP-retroviral vector in human , mouse , rat for TLN2 OriGene genome-wide validated SYBR primer pairs in human , mouse , rat for TLN2 Browse OriGene Protein Over-expression Lysates Browse OriGene Fluorogenic Cell Assay Kits OriGene siRNA for TLN2 OriGene 3'-UTR Clone for TLN2 OriGene untagged cDNA clones in CMV expression vector in human , mouse , rat for TLN2 OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human , mouse , rat for TLN2 Browse OriGene GFP tagged cDNA clones in CMV expression vector Browse OriGene MicroRNA Expression Plasmids Browse OriGene basic RS shRNAs Browse OriGene validated miRNA SYBR primer pairs Browse OriGene full length recombinant human proteins expressed in human HEK293 cells OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling OriGene Custom Antibody Services for TLN2 OriGene Custom Protein Services for TLN2 OriGene Custom Immunoassay Development
QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat TLN2 QIAGEN SeqTarget long-range PCR primers in human , mouse , rat for resequencing TLN2 QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TLN2 QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human , mouse , rat TLN2 QIAGEN QuantiFast Probe-based Assays in human , mouse , rat TLN2 QIAGEN QuantiTect SYBR Green Assays in human , mouse , rat TLN2
Search Tocris compounds for TLN2
TLN2 Proteins, Antibodies, CLIAs, and ELISAs
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TLN2
ThermoFisher Antibodies for TLN2
Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat TLN2
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