TLN1 Gene
protein-coding GIFtS: 63
GCID: GC09M035687
|
|
talin 1
(Previous symbol: TLN)
| |
Aliases
for TLN1 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Talin 11 2 | | TLN1 2 3 | | ILWEQ1 2 | | Talin-11 | | KIAA10273 |
Export aliases for TLN1 gene to outside databasesPrevious GC identifers: GC09M036009 GC09M035866 |
Summaries
for TLN1 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for TLN1:
This gene encodes a cytoskeletal protein that is concentrated in areas of cell-substratum and cell-cell contacts. Theencoded protein plays a significant role in the assembly of actin filaments and in spreading and migration of variouscell types, including fibroblasts and osteoclasts. It codistributes with integrins in the cell surface membrane inorder to assist in the attachment of adherent cells to extracellular matrices and of lymphocytes to other cells. TheN-terminus of this protein contains elements for localization to cell-extracellular matrix junctions. The C-terminuscontains binding sites for proteins such as beta-1-integrin, actin, and vinculin. (provided by RefSeq, Feb 2009)
UniProtKB/Swiss-Prot: TLN1_HUMAN, Q9Y490Function: Probably involved in connections of major cytoskeletal structures to the plasma membrane. High molecularweight cytoskeletal protein concentrated at regions of cell-substratum contact and, in lymphocytes, at cell-cellcontacts (By similarity)
Gene Wiki entry for TLN1
|
Genomic Views
for TLN1 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000009.11 NC_018920.1 NT_008413.18
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the TLN1 gene promoter:
AP-2alpha isoform 3 AP-1 STAT5A Nkx2-5 AP-2alpha isoform 2 c-Ets-1 C/EBPalpha AP-2alpha isoform 4 AP-2alpha AP-2alphaA
Other transcription factors
Search SABiosciences Chromatin IP Primers for TLN1
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TLN1 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 9p13 Ensembl cytogenetic band: 9p13.3 HGNC cytogenetic band: 9p23-p21TLN1 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 9 GeneLoc Exon Structure GeneLoc location for GC09M035687: view genomic region
(about GC identifiers)
Start:
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35,696,945 bp from pter |
End:
|
35,732,392 bp from pter |
Size:
|
35,448 bases |
Orientation:
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minus strand |
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Proteins
for TLN1 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: TLN1_HUMAN, Q9Y490 (See
protein sequence)Recommended Name: Talin-1 Size: 2541 amino acids; 269767 Da
Subunit: Binds with high affinity to VCL and with low affinity to integrins. Interacts with PTK2/FAK1 (By similarity).Interacts with PIP5K1C and NRAP. Interacts with LAYN. Interacts with SYNM
Subcellular location: Cell projection, ruffle membrane; Peripheral membrane protein; Cytoplasmic side (By similarity).Cytoplasm, cytoskeleton (By similarity). Note=Colocalizes with LAYN at the membrane ruffles (By similarity)
Sequence caution: Sequence=BAA82979.2; Type=Erroneous initiation;
2 PDB 3D structures from  and Proteopedia  for TLN1:1SYQ (3D)
4DJ9 (3D)
Secondary accessions: A6NMY0 Q86YD0 Q9NZQ2 Q9UHH8 Q9UPX3Explore the universe of human proteins at neXtProt for TLN1: NX_Q9Y490
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9Y490
TLN1 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_006280.3
ENSEMBL proteins: ENSP00000316029 ENSP00000442981 Reactome Protein details: Q9Y490
Human Recombinant Protein Products:
Gene Ontology (GO): 5/11 cellular component terms (GO ID links to tree view) (see all 11): About this table
TLN1 for ontologies About GeneDecksing
TLN1 Antibody Products:
Assay Products for TLN1: |
Protein
Domains /
Families
for TLN1 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
TLN1 for domains About GeneDecksing
5/13 InterPro domains/families (see all 13):Graphical View of Domain Structure for InterPro Entry Q9Y490ProtoNet protein and cluster: Q9Y490 2 Blocks protein families: IPB000299 Band 4.1 domain IPB002558 I/LWEQ domain
UniProtKB/Swiss-Prot: TLN1_HUMAN, Q9Y490Similarity: Contains 1 FERM domainSimilarity: Contains 1 I/LWEQ domain |
Function
for TLN1 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: TLN1_HUMAN, Q9Y490Function: Probably involved in connections of major cytoskeletal structures to the plasma membrane. High molecularweight cytoskeletal protein concentrated at regions of cell-substratum contact and, in lymphocytes, at cell-cellcontacts (By similarity)
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TLN1 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TLN1
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
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In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TLN1 |
Gene Ontology (GO): 5/6 molecular function terms (GO ID links to tree view) (see all 6): About this table
TLN1 for ontologies About GeneDecksing
2 GenomeRNAi human phenotypes for TLN1:
Animal Models:
Mouse knock-outs for TLN1: Tln1tm3Crit Tln1tm1Crit
10 MGI mutant phenotypes (inferred from 5 alleles ) (MGI details for Tln1):
TLN1 for phenotypes About GeneDecksing
|
Pathways & Interactions
for TLN1 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways - 5/31 super-pathways (see all 31) About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Cell adhesion_Integrin-mediated cell adhesion and migration | | | 2 | GRB2:SOS provides linkage to MAPK signaling for Intergrins | | | 3 | Activation of Chaperone Genes by XBP1(S) | | | 4 | Focal Adhesion | | | 5 | Cell adhesion_Integrin inside-out signaling | |
Pathway sources
See GeneCards unified pathways
Show all pathways
5 EMD Millipore Pathways for TLN1
5/6 Downloadable PowerPoint Slides of QIAGEN Pathway Central Maps for TLN1 (see all 6)
1 
Cell Signaling Technology (CST) Pathway for TLN1
5/6  GeneGo (Thomson Reuters) Pathways for TLN1 (see all 6)
5/9  BioSystems Pathways for TLN1 (see all 9)
5/23 
Reactome Pathways for TLN1 (see all 23)
1 
Kegg Pathway (Kegg details for TLN1):
TLN1 for pathways About GeneDecksing
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for TLN1
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/894 Interacting proteins for TLN1 (Q9Y4902, 3 ENSP000003160294) via UniProtKB, MINT, STRING, and/or I2D (see all 894)About this table
Gene Ontology (GO): 5/13 biological process terms (GO ID links to tree view) (see all 13): About this table
TLN1 for ontologies About GeneDecksing
|
Drugs & Compounds
for TLN1 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for TLN1
Search CenterWatch for drugs/clinical trials and news about TLN1
|
Transcripts
for TLN1 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for TLN1 gene: NM_006289.3 Unigene Cluster for TLN1: Talin 1 Hs.471014 [show with all ESTs]Unigene Representative Sequence: NM_0062899 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000314888(uc003zxt.2) ENST00000489255 ENST00000464379 ENST00000466916
ENST00000465002 ENST00000486788 ENST00000495712 ENST00000378192(uc003zxu.4)
ENST00000540444
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TLN1 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TLN1
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: TLN1 (NM_006289) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for TLN1 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TLN1 |
Additional cDNA sequence: AB028950.2 AF001392.1 AF078828.1 AF113217.1 AF177198.1 AK001026.1 BC020881.1 BC042923.1 Z50170.1 24/29 DOTS entries (see all 29): DT.92451593 DT.92451583 DT.315829 DT.100825199 DT.91770045 DT.95130790 DT.121191152 DT.91655792 DT.97860687 DT.121191075 DT.100825193 DT.95149204 DT.310205 DT.95149200 DT.91732564 DT.95149192 DT.99977584 DT.100825197 DT.100825201 DT.100825202 DT.121191034 DT.121191135 DT.121191161 DT.91738345 24/835 AceView cDNA sequences (see all 835): BE277380 BQ710316 BQ777777 BQ641725 BE910015 CA455027 BI063682 AL042809 BG748469 BU172153 BU185977 CF131236 BG387055 BF360434 BM542656 BI916838 BM468367 BQ070623 BM703003 BQ946645 BG763422 BU145903 BQ690373 BU149396
GeneLoc Exon Structure
|
Expression
for TLN1 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| TLN1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CTCCAATAAA
About this image
See TLN1 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for TLN1
SOURCE GeneReport for Unigene cluster: Hs.471014
SABiosciences Expression via Pathway-Focused PCR Arrays including TLN1:
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for TLN1
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat TLN1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TLN1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TLN1 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TLN1 |
Orthologs
for TLN1 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for TLN1 gene from 6/23 species (see all 23) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
TLN11 |
talin 1 |
80.37(n)
89.16(a) |
|
395194 NM_204523.1 NP_989854.1 |
lizard
(Anolis carolinensis) |
Reptilia |
TLN16-- |
-- |
88(a)74(a) |
1 ↔ 1possible ortholog |
GL343746.1(7414-64035) GL343847.1(34518-39962) |
African clawed frog
(Xenopus laevis) |
Amphibia |
Xl.184672 |
Xenopus laevis transcribed sequence with strong similarity more |
87.15(n) |
|
BI347878.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
sbcb8542 |
sbcb854 |
77.8(n) |
|
378871 CK028724.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
Talin3 |
cytoskeletal anchoring actin binding |
46(a) |
|
66D6 -- |
worm
(Caenorhabditis elegans) |
Secernentea |
Y71G12B.11b3 |
-- |
41(a)
(best of 2) |
|
I(1721598-1732876) -- |
ENSEMBL Gene Tree for TLN1 (if available)
TreeFam Gene Tree for TLN1 (if available) |
Paralogs
for TLN1 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for TLN1 gene
- TLN22 HIP12 HIP1R2 MESDC12
1 SIMAP similar gene for TLN1 using alignment to 2 protein entries: TLN1_HUMAN (see all proteins):TLN2
TLN1 for paralogs About GeneDecksing
|
Genomic Variants
for TLN1 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 9 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for TLN1 (35696945 - 35732392 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 2 variations for TLN1
1 CNV: 65382
1 Indel: 59528 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing TLN1 |
|
Disorders
/ Diseases
for TLN1 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
TLN1 for disorders About GeneDecksing
OMIM gene information: 186745
OMIM disorders: --
6  diseases for TLN1: About MalaCardsembryonal rhabdomyosarcoma dilated cardiomyopathy rhabdomyosarcoma cardiomyopathy
psoriasis carcinoma
Export disorders for TLN1 gene to outside databases
|
Publications
for TLN1 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for TLN1 gene, integrated from 9 sources (see all 113):
(articles sorted by number of sources associating them with TLN1) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Characterization of the human talin (TLN) gene: genomic structure, chromosomal localization, and expression pattern. (PubMed id 10610730)1, 2, 3, 9 Ben-Yosef T. and Francomano C.A. (1999)
- Identification of a repeated domain within mammalian alpha-synemin that interacts directly with talin. (PubMed id 18342854)1, 2 Sun N.... Robson R.M. (2008)
- Structural basis for amplifying vinculin activation by talin. (PubMed id 15070891)1, 2 Izard T. and Vonrhein C. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Type I gamma phosphatidylinositol phosphate kinase targets and regulates focal adhesions. (PubMed id 12422220)1, 2 Ling K.... Anderson R.A. (2002)
- Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones. (PubMed id 12168954)1, 2 Nakajima D.... Nagase T. (2002)
- Prediction of the coding sequences of unidentified human genes. XIV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 10470851)1, 2 Kikuno R....Ohara O. (1999)
- Molecular interactions of N-RAP, a nebulin-related protein of striated muscle myotendon junctions and intercalated disks. (PubMed id 10320340)1, 2 Luo G.... Horowits R. (1999)
- Localisation of the human gene encoding the cytoskeletal protein talin to chromosome 9p. (PubMed id 7635475)1, 3 Gilmore A.P....Critchley D.R. (1995)
- Talin 1 and paxillin facilitate distinct steps in rapid VLA-4-mediated adhesion strengthening to vascular cell adhesion molecule 1. (PubMed id 17597073)1, 9 Manevich E....Alon R. (2007)
|
External Searches for TLN1 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing TLN1 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing TLN1 gene
(According to HUGE)
About This Section
| |
Specialized Databases showing TLN1 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
|
About This Section
| Patent Information for TLN1 gene:
Search GeneIP for patents involving TLN1
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for TLN1 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | OriGene Antibodies for TLN1 | | OriGene shRNA RFP for TLN1 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for TLN1 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for TLN1 | | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for TLN1 | | OriGene 3'-UTR Clone for TLN1 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TLN1 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TLN1 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for TLN1 | | OriGene Custom Protein Services for TLN1 | | | OriGene Custom Immunoassay Development | | |
| |
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 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat TLN1 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing TLN1 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TLN1 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TLN1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TLN1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TLN1 |
| |
 |  |  |  | |
| | Antibodies & Assays for TLN1
(talin 1) |
| | | | Search Tocris compounds for TLN1 |
| |  |  |  |  | | | | |
 |
 |
 |
 | | | TLN1 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TLN1 |
|  |  |  | | | | ThermoFisher Antibodies for TLN1 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TLN1 |
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