External Ids for TLL2 Gene
Previous GeneCards Identifiers for TLL2 Gene
This gene encodes an astacin-like zinc-dependent metalloprotease and is a subfamily member of the metzincin family. Unlike other family members, a similar protein in mice does not cleave procollagen C-propeptides or chordin. [provided by RefSeq, Jul 2008]
GeneCards Summary for TLL2 Gene
TLL2 (Tolloid Like 2) is a Protein Coding gene. Diseases associated with TLL2 include Autosomal Recessive Non-Syndromic Intellectual Disability. Among its related pathways are Collagen biosynthesis and modifying enzymes and Degradation of the extracellular matrix. GO annotations related to this gene include calcium ion binding and metallopeptidase activity. An important paralog of this gene is BMP1.
UniProtKB/Swiss-Prot for TLL2 Gene
Protease which specifically processes pro-lysyl oxidase. Required for the embryonic development. Predominant protease, which in the development, influences dorsal-ventral patterning and skeletogenesis.