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TLE6 Gene

protein-coding   GIFtS: 47
GCID: GC19P002976

Transducin-Like Enhancer Of Split 6

(Previous names: transducin-like enhancer of split 6 (E(sp1) homolog, Drosophila))
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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Transducin-Like Enhancer Of Split 61 2
Transducin-Like Enhancer Of Split 6 (E(Sp1) Homolog, Drosophila)1 2
GRG62 5
Transducin-Like Enhancer Protein 62

External Ids:    HGNC: 307881   Entrez Gene: 798162   Ensembl: ENSG000001049537   OMIM: 6123995   UniProtKB: Q9H8083   

Export aliases for TLE6 gene to outside databases

Previous GC identifers: GC19P002930 GC19P002745


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for TLE6 Gene:
TLE6 (transducin-like enhancer of split 6) is a protein-coding gene. An important paralog of this gene is AES.

UniProtKB/Swiss-Prot: TLE6_HUMAN, Q9H808
Function: As a member of the subcortical maternal complex (SCMC), plays an essential role for zygotes to progress
beyond the first embryonic cell divisions (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000019.9  NT_011295.12  NC_018930.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the TLE6 gene promoter:
         USF1   p53   AP-1   ATF-2   USF2   LUN-1   USF-1:USF-2   c-Ets-1   USF-1   c-Jun   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidTLE6 promoter sequence
   Search Chromatin IP Primers for TLE6

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat TLE6


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 19p13.3   Ensembl cytogenetic band:  19p13.3   HGNC cytogenetic band: 19p13.3

TLE6 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TLE6 gene location

GeneLoc information about chromosome 19         GeneLoc Exon Structure

GeneLoc location for GC19P002976:  view genomic region     (about GC identifiers)

Start:
2,977,444 bp from pter      End:
2,995,182 bp from pter
Size:
17,739 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: TLE6_HUMAN, Q9H808 (See protein sequence)
Recommended Name: Transducin-like enhancer protein 6  
Size: 572 amino acids; 63473 Da
Subunit: Component of the SCMC which also includes at least OOEP and NLRP5
Sequence caution: Sequence=AAH20206.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
Secondary accessions: J3KMZ1
Alternative splicing: 2 isoforms:  Q9H808-1   Q9H808-2   

Explore the universe of human proteins at neXtProt for TLE6: NX_Q9H808

Explore proteomics data for TLE6 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See TLE6 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (2 alternative transcripts): 
    NP_001137458.1  NP_079036.1  

    ENSEMBL proteins: 
     ENSP00000246112   ENSP00000411783   ENSP00000467126   ENSP00000406893  

    TLE6 Human Recombinant Protein Products:

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    Novus Biologicals TLE6 Protein
    Novus Biologicals TLE6 Lysates
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    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for TLE6

     
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    antibodies-online proteins for TLE6 (4 products) 

     
    antibodies-online peptides for TLE6

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    antibodies-online antibodies for TLE6 (11 products) 

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    WDR: WD repeat domain containing

    4 InterPro protein domains:
     IPR009146 Groucho_enhance
     IPR001680 WD40_repeat
     IPR017986 WD40_repeat_dom
     IPR015943 WD40/YVTN_repeat-like_dom

    Graphical View of Domain Structure for InterPro Entry Q9H808

    ProtoNet protein and cluster: Q9H808

    1 Blocks protein domain: IPB009146 Groucho/transducin-like enhancer protein signature

    UniProtKB/Swiss-Prot: TLE6_HUMAN, Q9H808
    Similarity: Belongs to the WD repeat Groucho/TLE family
    Similarity: Contains 7 WD repeats


    Find genes that share domains with TLE6           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: TLE6_HUMAN, Q9H808
    Function: As a member of the subcortical maternal complex (SCMC), plays an essential role for zygotes to progress
    beyond the first embryonic cell divisions (By similarity)

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding ----
         
    Find genes that share ontologies with TLE6           About GenesLikeMe


    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for TLE6
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for TLE6
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for TLE6

    miRNA
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    1 qRT-PCR Assays for microRNA that regulate TLE6:
    hsa-miR-556-3p
    SwitchGear 3'UTR luciferase reporter plasmidTLE6 3' UTR sequence
    Inhib. RNA
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    OriGene RNAi products in human, mouse, rat for TLE6
    Predesigned siRNA for gene silencing in human, mouse, rat TLE6

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    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TLE6
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TLE6

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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TLE6


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    TLE6_HUMAN, Q9H808: Cytoplasm. Note=In the subcortical cytoplasm of early embryos from the 1-cell to the
    blastocyst stages. From the 2-cell stage, still detected in the subcortex, but excluded from cell-cell contact
    regions (By similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol2
    nucleus2
    mitochondrion1

    Gene Ontology (GO): 3 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IEA--
    GO:0005938cell cortex IEA--
    GO:0043234protein complex IEA--

    Find genes that share ontologies with TLE6           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for TLE6 About    
    See pathways by source

    SuperPathContained pathways About
    1Wnt signaling pathway (KEGG)
    Wnt Signaling Pathways0.40

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways

    1 R&D Systems Pathway for TLE6
        Wnt Signaling Pathways



        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for TLE6
    Interactions:

        Search GeneGlobe Interaction Network for TLE6

    STRING Interaction Network Preview (showing 5 interactants - click image to see 15)

    Selected Interacting proteins for TLE6 (Q9H8083 ENSP000002461124) via UniProtKB, MINT, STRING, and/or I2D (see all 27)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    FOXP1Q9H3343, ENSP000003189024I2D: score=1 STRING: ENSP00000318902
    TCF3P159233, ENSP000002629654I2D: score=1 STRING: ENSP00000262965
    KHDC3LQ587J83, ENSP000003593924I2D: score=1 STRING: ENSP00000359392
    OOEPA6NGQ23, ENSP000003593844STRING: ENSP00000359384 I2D: score=3 
    NLRP5P590473, ENSP000003750634I2D: score=3 STRING: ENSP00000375063
    About this table

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006355regulation of transcription, DNA-templated IEA--

    Find genes that share ontologies with TLE6           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for TLE6



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for TLE6 gene (2 alternative transcripts): 
    NM_001143986.1  NM_024760.2  

    Unigene Cluster for TLE6:

    Transducin-like enhancer of split 6 (E(sp1) homolog, Drosophila)
    Hs.334507  [show with all ESTs]
    Unigene Representative Sequence: NM_001143986
    10 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000246112(uc002lwt.2 uc002lwu.2) ENST00000453329 ENST00000482627
    ENST00000468176 ENST00000452088 ENST00000591953 ENST00000478073 ENST00000474207
    ENST00000497878 ENST00000469572
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat TLE6 using miScript Target Protectors
    1 qRT-PCR Assays for microRNA that regulate TLE6:
    hsa-miR-556-3p
    SwitchGear 3'UTR luciferase reporter plasmidTLE6 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for TLE6
    Predesigned siRNA for gene silencing in human, mouse, rat TLE6
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    GenScript: all cDNA clones in your preferred vector (see all 2): TLE6 (NM_001143986)
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TLE6
    Primer
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    OriGene qPCR primer pairs and template standards for TLE6
    OriGene qSTAR qPCR primer pairs in human, mouse for TLE6
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat TLE6
      QuantiTect SYBR Green Assays in human, mouse, rat TLE6
      QuantiFast Probe-based Assays in human, mouse, rat TLE6

    Additional mRNA sequence: 

    AK024071.1 BC007215.1 BC007329.2 BC013986.2 BC020206.1 BC068052.1 

    7 DOTS entries:

    DT.40127441  DT.99945082  DT.100751057  DT.100751056  DT.100768196  DT.100845117  DT.121452060 

    Selected AceView cDNA sequences (see all 55):

    BX375734 BM694870 BC007329 NM_024760 BX089956 CR607853 AK024071 BP357221 
    CR590811 BC013986 CB104948 BC068052 BC020206 BM744758 BM718930 AU143748 
    BX361000 AA975026 BX350364 BG437480 CB128659 CB127786 AW450777 BX360999 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for TLE6 (see all 9)    About this scheme

    ExUns: 1a · 1b · 1c · 1d ^ 2 ^ 3a · 3b ^ 4 ^ 5 ^ 6a · 6b · 6c ^ 7 ^ 8a · 8b · 8c · 8d ^ 9 ^ 10 ^ 11 ^ 12a · 12b ^ 13 ^ 14a · 14b ^ 15 ^
    SP1:                                                                                                                          -                                 
    SP2:                                      -                 -     -     -                                                                                       
    SP3:                    -                 -                 -     -     -                                                                                       
    SP4:                          -           -                 -     -     -                                                                                       
    SP5:                                                                    -                                                                                       

    ExUns: 16 ^ 17
    SP1:            
    SP2:            
    SP3:            
    SP4:            
    SP5:            


    ECgene alternative splicing isoforms for TLE6

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    TLE6 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GTGGAGGGAA
    TLE6 Expression
    About this image


    TLE6 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 3) fully expand
     
     Ovary (Reproductive System)
             Secondary follicles
     
     Neural Tube (Nervous System)
             Floor plate-like cells
     
     Stomach (Gastrointestinal Tract)
    TLE6 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    TLE6 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.334507
        Custom PCR Arrays for TLE6
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TLE6

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for TLE6 gene from Selected species (see all 9)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Tle61 , 5 transducin-like enhancer of split 6, homolog of Drosophila more1, 5 64.53(n)1
    52.75(a)1
      10 (39.72 cM)5
    1146061  NM_053254.21  NP_444484.11 
     815909045 
    lizard
    (Anolis carolinensis)
    Reptilia --
    Uncharacterized protein
    20(a)
    many ↔ many
    GL344313.1(22075-43850)
    zebrafish
    (Danio rerio)
    Actinopterygii si:dkey-42p8.36
    si:dkey-42p8.3
    17(a)
    many ↔ many
    22(21994430-22077298) ENSDARG00000008767


    ENSEMBL Gene Tree for TLE6 (if available)
    TreeFam Gene Tree for TLE6 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for TLE6 gene
    AES2  TLE32  TLE22  TLE42  TLE12  
    3 SIMAP similar genes for TLE6 using alignment to 4 protein entries:     TLE6_HUMAN (see all proteins):
    TLE4    TLE3    TLE2

    Find genes that share paralogs with TLE6           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for TLE6 (see all 702)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 19 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1466667331,2
    --2975546(+) GTTCAA/GGTGAT 2 -- us2k10--------
    rs3715094041,2
    C--2975642(+) GGTTT-/CTTTTT 2 -- us2k10--------
    rs615428591,2
    C--2975643(+) TTTTT-/TGAGAC 2 -- us2k10--------
    rs1807258581,2
    --2975736(+) CCTCCC/TGGGTT 2 -- us2k10--------
    rs343823121,2
    C--2975745(+) TTCACA/GCCATT 2 -- us2k10--------
    rs72602151,2
    C,A--2975762(+) cctcaA/Gcctcc 2 -- us2k10--------
    rs1483471281,2
    --2975971(+) GGTCTC/TGAACC 2 -- us2k10--------
    rs1415381571,2
    C--2976032(+) CAGGCA/GTGCAC 2 -- us2k10--------
    rs20521201,2
    C,F,A,H--2976114(+) CTGAGG/AGAGAC 2 -- us2k124Minor allele frequency- A:0.26NS EA NA CSA WA 2526
    rs1504627961,2
    --2976127(+) TCCCTA/GGCAGA 2 -- us2k10--------

    HapMap Linkage Disequilibrium report for TLE6 (2977444 - 2995182 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 4 variations for TLE6:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv910694CNV Loss21882294
    nsv833709CNV Loss17160897
    dgv47n68CNV Loss17160897
    nsv910695CNV Loss21882294

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing TLE6
    DNA2.0 Custom Variant and Variant Library Synthesis for TLE6

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 612399    OMIM disorders: --


    Find genes that share disorders with TLE6           About GenesLikeMe


    Export disorders for TLE6 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

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    PubMed articles for TLE6 gene integrated from 10 sources:
    (articles sorted by number of sources associating them with TLE6)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    3. The E2A-HLF oncoprotein activates Groucho-related genes and suppresses Runx1. (PubMed id 11486032)1, 3 Dang J....Look A.T. (Mol. Cell. Biol. 2001)
    4. Toward an understanding of the protein interaction network of the human liver. (PubMed id 21988832)1 Wang J....Yang X. (Mol. Syst. Biol. 2011)
    5. Novel roles for MLH3 deficiency and TLE6-like amplification in DNA mismatch repair-deficient gastrointestinal tumorigenesis and progression. (PubMed id 18551179)1 Chen P.C....Lipkin S.M. (PLoS Genet. 2008)
    6. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (Genome Res. 2006)
    7. The DNA sequence and biology of human chromosome 19. (PubMed id 15057824)2 Grimwood J.... Lucas S.M. (Nature 2004)
    8. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 79816 HGNC: 30788 AceView: FLJ14009 Ensembl:ENSG00000104953 euGenes: HUgn79816
    ECgene: TLE6 H-InvDB: TLE6

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for TLE6 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for TLE6 gene:
    Search GeneIP for patents involving TLE6

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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