Aliases for TLE2 Gene
External Ids for TLE2 Gene
Previous GeneCards Identifiers for TLE2 Gene
GeneCards Summary for TLE2 Gene
TLE2 (Transducin Like Enhancer Of Split 2) is a Protein Coding gene. Among its related pathways are Wnt / Hedgehog / Notch and Wnt Signaling Pathways: beta-Catenin-independent Wnt/PCP Signaling Pathways. GO annotations related to this gene include transcription corepressor activity. An important paralog of this gene is AES.
UniProtKB/Swiss-Prot for TLE2 Gene
Transcriptional corepressor that binds to a number of transcription factors. Inhibits the transcriptional activation mediated by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES (By similarity).