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Aliases for TLDC2 Gene

Aliases for TLDC2 Gene

  • TBC/LysM-Associated Domain Containing 2 2 3
  • TBC/LysM-Associated Domain-Containing Protein 2 3 4
  • Chromosome 20 Open Reading Frame 118 2
  • TLD Domain-Containing Protein 2 3
  • Hypothetical Protein LOC140711 2
  • TLD Domain Containing 2 2
  • C20orf118 3

External Ids for TLDC2 Gene

Previous HGNC Symbols for TLDC2 Gene

  • C20orf118

Previous GeneCards Identifiers for TLDC2 Gene

  • GC20P035505

Summaries for TLDC2 Gene

GeneCards Summary for TLDC2 Gene

TLDC2 (TBC/LysM-Associated Domain Containing 2) is a Protein Coding gene. An important paralog of this gene is NCOA7.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TLDC2 Gene

Genomics for TLDC2 Gene

Genomic Location for TLDC2 Gene

Start:
36,876,121 bp from pter
End:
36,894,235 bp from pter
Size:
18,115 bases
Orientation:
Plus strand

Genomic View for TLDC2 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for TLDC2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TLDC2 Gene

No data available for Regulatory Elements for TLDC2 Gene

Proteins for TLDC2 Gene

  • Protein details for TLDC2 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    A0PJX2-TLDC2_HUMAN
    Recommended name:
    TLD domain-containing protein 2
    Protein Accession:
    A0PJX2
    Secondary Accessions:
    • B3KVU8

    Protein attributes for TLDC2 Gene

    Size:
    215 amino acids
    Molecular mass:
    23912 Da
    Quaternary structure:
    No Data Available

neXtProt entry for TLDC2 Gene

Proteomics data for TLDC2 Gene at MOPED

Post-translational modifications for TLDC2 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for TLDC2 Gene

No data available for DME Specific Peptides for TLDC2 Gene

Domains for TLDC2 Gene

Protein Domains for TLDC2 Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

A0PJX2

UniProtKB/Swiss-Prot:

TLDC2_HUMAN :
  • A0PJX2
Domain:
  • Contains 1 TLD domain.
Family:
  • Belongs to the OXR1 family.
genes like me logo Genes that share domains with TLDC2: view

No data available for Gene Families and Suggested Antigen Peptide Sequences for TLDC2 Gene

Function for TLDC2 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for TLDC2 Gene

Localization for TLDC2 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for TLDC2 Gene

Pathways for TLDC2 Gene

SuperPathways for TLDC2 Gene

No Data Available

Interacting Proteins for TLDC2 Gene

STRING Interaction Network Preview (showing 4 interactants - click image to see details)
http://string-db.org/version_10/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000217320%0d%0a9606.ENSP00000256031%0d%0a9606.ENSP00000327214%0d%0a9606.ENSP00000341942%0d%0a9606.ENSP00000339182%0d%0a
Selected Interacting proteins: ENSP00000217320 for TLDC2 Gene via STRING

Gene Ontology (GO) - Biological Process for TLDC2 Gene

None

No data available for Pathways by source for TLDC2 Gene

Transcripts for TLDC2 Gene

mRNA/cDNA for TLDC2 Gene

(4) Additional mRNA sequences :
(4) REFSEQ mRNAs :
(3) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for TLDC2 Gene

TBC/LysM-associated domain containing 2:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for TLDC2 Gene

No ASD Table

Relevant External Links for TLDC2 Gene

GeneLoc Exon Structure for
TLDC2
ECgene alternative splicing isoforms for
TLDC2

Expression for TLDC2 Gene

mRNA expression in normal human tissues for TLDC2 Gene

mRNA differential expression in normal tissues according to GTEx for TLDC2 Gene

This gene is overexpressed in Colon - Transverse (15.3), Small Intestine - Terminal Ileum (13.4), and Kidney - Cortex (7.0).

SOURCE GeneReport for Unigene cluster for TLDC2 Gene Hs.472630

genes like me logo Genes that share expressions with TLDC2: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein expression and mRNA Expression by UniProt/SwissProt for TLDC2 Gene

Orthologs for TLDC2 Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for TLDC2 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia TLDC2 35
  • 99.69 (n)
  • 100 (a)
TLDC2 36
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia TLDC2 35
  • 86.05 (n)
  • 84.19 (a)
TLDC2 36
  • 83 (a)
OneToOne
dog
(Canis familiaris)
Mammalia TLDC2 35
  • 84.81 (n)
  • 83.72 (a)
TLDC2 36
  • 81 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Gm1332 16
Tldc2 35
  • 82.08 (n)
  • 82.55 (a)
Tldc2 36
  • 84 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia TLDC2 36
  • 70 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia TLDC2 36
  • 75 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Tldc2 35
  • 83.02 (n)
  • 81.9 (a)
chicken
(Gallus gallus)
Aves TLDC2 35
  • 66.27 (n)
  • 59.88 (a)
TLDC2 36
  • 54 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia TLDC2 36
  • 56 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia tldc2 35
  • 57.05 (n)
  • 47.91 (a)
zebrafish
(Danio rerio)
Actinopterygii TLDC2 36
  • 13 (a)
OneToOne
fruit fly
(Drosophila melanogaster)
Insecta mtd 36
  • 7 (a)
OneToOne
worm
(Caenorhabditis elegans)
Secernentea lmd-3 36
  • 9 (a)
OneToOne
A. gosspyii yeast
(Ashbya gossypii)
Saccharomycetes AGOS_AFL078W 35
  • 51.57 (n)
  • 38.99 (a)
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes OXR1 35
  • 43.33 (n)
  • 38 (a)
OXR1 38
K. lactis yeast
(Kluyveromyces lactis)
Saccharomycetes KLLA0E19449g 35
  • 45.56 (n)
  • 39.33 (a)
bread mold
(Neurospora crassa)
Ascomycetes NCU02394 35
  • 44.33 (n)
  • 31.96 (a)
Species with no ortholog for TLDC2:
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for TLDC2 Gene

ENSEMBL:
Gene Tree for TLDC2 (if available)
TreeFam:
Gene Tree for TLDC2 (if available)

Paralogs for TLDC2 Gene

Paralogs for TLDC2 Gene

Selected SIMAP similar genes for TLDC2 Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with TLDC2: view

Variants for TLDC2 Gene

Sequence variations from dbSNP and Humsavar for TLDC2 Gene

SNP ID Clin Chr 20 pos Sequence Context AA Info Type MAF
rs1024191 -- 36,879,632(+) aggag(A/T)tcaag intron-variant
rs1291118 -- 36,874,778(+) ggagg(C/G)agagg upstream-variant-2KB
rs1291119 -- 36,875,006(+) ggtgg(C/T)gggtg upstream-variant-2KB
rs1291120 -- 36,875,047(+) gcagg(A/G)gaatg upstream-variant-2KB
rs1291121 -- 36,875,575(+) ctggg(C/T)ttacc upstream-variant-2KB

Relevant External Links for TLDC2 Gene

HapMap Linkage Disequilibrium report
TLDC2

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for TLDC2 Gene

Disorders for TLDC2 Gene

No disorders were found for TLDC2 Gene.

No data available for UniProtKB/Swiss-Prot for TLDC2 Gene

Publications for TLDC2 Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 4
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4

Products for TLDC2 Gene

Sources for TLDC2 Gene

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