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Aliases for TINCR Gene

Subcategory (RNA class) for TINCR Gene

lncRNA

Quality Score for this RNA gene is

3

Aliases for TINCR Gene

  • Tissue Differentiation-Inducing Non-Protein Coding RNA 2 3
  • Long Intergenic Non-Protein Coding RNA 36 2 3
  • Placenta-Specific 2 (Non-Protein Coding) 2 3
  • Terminal Differentiation-Induced NcRNA 2 3
  • Non-Protein Coding RNA 36 2
  • Placenta-Specific 2 2
  • NCRNA00036 3
  • LINC00036 3
  • PLAC2 3

External Ids for TINCR Gene

Previous Symbols for TINCR Gene

  • PLAC2

Summaries for TINCR Gene

Entrez Gene Summary for TINCR Gene

  • This gene produces a spliced long non-coding RNA that is required for normal epidermal differentiation. This transcript regulates the expression of genes involved in the differentiation of epidermal tissue. Mutations in some of the genes targeted by this transcript have been implicated in epidermal skin diseases. [provided by RefSeq, Apr 2015]

GeneCards Summary for TINCR Gene

TINCR (Tissue Differentiation-Inducing Non-Protein Coding RNA) is a RNA Gene, and belongs to lncRNA RNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TINCR Gene

Genomics for TINCR Gene

Genomic Location for TINCR Gene

Start:
5,558,167 bp from pter
End:
5,568,034 bp from pter
Size:
9,868 bases
Orientation:
Minus strand

Genomic View for TINCR Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for TINCR Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TINCR Gene

No data available for Regulatory Elements for TINCR Gene

Proteins for TINCR Gene

Post-translational modifications for TINCR Gene

No Post-translational modifications

No data available for DME Specific Peptides for TINCR Gene

Domains for TINCR Gene

Gene Families for TINCR Gene

HGNC:
  • LNCRNA :Long non-coding RNAs
genes like me logo Genes that share domains with TINCR: view

No data available for Protein Domains and UniProtKB/Swiss-Prot for TINCR Gene

Function for TINCR Gene

Phenotypes for TINCR Gene

GenomeRNAi human phenotypes for TINCR:
genes like me logo Genes that share phenotypes with TINCR: view

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for TINCR Gene

Localization for TINCR Gene

No data available for Gene Ontology (GO) - Cellular Components for TINCR Gene

Pathways for TINCR Gene

SuperPathways for TINCR Gene

No Data Available

Interacting Proteins for TINCR Gene

Gene Ontology (GO) - Biological Process for TINCR Gene

None

No data available for Pathways by source for TINCR Gene

Transcripts for TINCR Gene

mRNA/cDNA for TINCR Gene

Unigene Clusters for TINCR Gene

Tissue differentiation-inducing non-protein coding RNA:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for TINCR Gene

No ASD Table

Relevant External Links for TINCR Gene

GeneLoc Exon Structure for
TINCR
ECgene alternative splicing isoforms for
TINCR

Expression for TINCR Gene

mRNA expression in normal human tissues for TINCR Gene

mRNA differential expression in normal tissues according to GTEx for TINCR Gene

This gene is overexpressed in Skin - Sun Exposed (Lower leg) (14.2), Skin - Not Sun Exposed (Suprapubic) (12.8), and Esophagus - Mucosa (5.0).

SOURCE GeneReport for Unigene cluster for TINCR Gene Hs.515575

genes like me logo Genes that share expressions with TINCR: view

Orthologs for TINCR Gene

Evolution for TINCR Gene

ENSEMBL:
Gene Tree for TINCR (if available)
TreeFam:
Gene Tree for TINCR (if available)

No data available for Orthologs for TINCR Gene

Paralogs for TINCR Gene

No data available for Paralogs for TINCR Gene

Variants for TINCR Gene

Sequence variations from dbSNP and Humsavar for TINCR Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type MAF
rs749213 -- 5,564,229(-) TAGGG(A/T)GAGAG intron-variant
rs1806964 -- 5,563,732(+) caaca(A/T)ggtga intron-variant
rs2288946 -- 5,562,073(+) CTACA(A/G)TTACT intron-variant
rs2288947 -- 5,562,104(+) CTCCC(A/G)GGAGG nc-transcript-variant
rs7246801 -- 5,564,522(+) AGGGA(C/T)GGGCA intron-variant

Relevant External Links for TINCR Gene

HapMap Linkage Disequilibrium report
TINCR

No data available for Structural Variations from Database of Genomic Variants (DGV) for TINCR Gene

Disorders for TINCR Gene

No disorders were found for TINCR Gene.

No data available for UniProtKB/Swiss-Prot for TINCR Gene

Publications for TINCR Gene

  1. Control of somatic tissue differentiation by the long non-coding RNA TINCR. (PMID: 23201690) Kretz M. … Khavari P.A. (Nature 2013) 2 3
  2. TINCR, staufen1, and cellular differentiation. (PMID: 24019000) Kretz M. (RNA Biol 2013) 2 3
  3. Transcriptome analysis of psoriasis in a large case-control sample: RNA-seq provides insights into disease mechanisms. (PMID: 24441097) Li B. … Elder J.T. (J. Invest. Dermatol. 2014) 3
  4. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3
  5. A LncRNA-MAF:MAFB Transcription Factor Network Regulates Epidermal Differentiation. (PMID: 25805135) Lopez-Pajares V. … Khavari P.A. (Dev. Cell 2015) 3

Products for TINCR Gene

  • QIAGEN qRT-PCR Assays for microRNAs that regulate TINCR
    • QuantiTect SYBR Green Assays in human,mouse,rat
    • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
    • QuantiFast Probe-based Assays in human,mouse,rat
    • Predesigned siRNA for gene silencing in human,mouse,rat for TINCR
    • Block miRNA regulation of TINCR using miScript Target Protectors

    Sources for TINCR Gene

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