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Aliases for TINCR Gene

Subcategory (RNA class) for TINCR Gene

non-coding RNA

Quality Score for this RNA gene is


Aliases for TINCR Gene

  • Tissue Differentiation-Inducing Non-Protein Coding RNA 2 3 5
  • Long Intergenic Non-Protein Coding RNA 36 2 3
  • Placenta-Specific 2 (Non-Protein Coding) 2 3
  • Terminal Differentiation-Induced NcRNA 2 3
  • Non-Protein Coding RNA 36 2
  • Placenta-Specific 2 2
  • Onco-LncRNA-16 3
  • NCRNA00036 3
  • LINC00036 3
  • PLAC2 3

External Ids for TINCR Gene

Previous HGNC Symbols for TINCR Gene

  • PLAC2

Summaries for TINCR Gene

Entrez Gene Summary for TINCR Gene

  • This gene produces a spliced long non-coding RNA that is required for normal epidermal differentiation. This transcript regulates the expression of genes involved in the differentiation of epidermal tissue. Mutations in some of the genes targeted by this transcript have been implicated in epidermal skin diseases. [provided by RefSeq, Apr 2015]

GeneCards Summary for TINCR Gene

TINCR (Tissue Differentiation-Inducing Non-Protein Coding RNA) is an RNA Gene, and is affiliated with the non-coding RNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TINCR Gene

Genomics for TINCR Gene

Regulatory Elements for TINCR Gene

Enhancers for TINCR Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
- Elite enhancer/Elite enhancer-gene association

Enhancers around TINCR on UCSC Golden Path with GeneCards custom track

Promoters for TINCR Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

Genomic Location for TINCR Gene

5,558,167 bp from pter
5,568,034 bp from pter
9,868 bases
Minus strand

Genomic View for TINCR Gene

Genes around TINCR on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TINCR Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TINCR Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TINCR Gene

Proteins for TINCR Gene

Post-translational modifications for TINCR Gene

No Post-translational modifications

Other Protein References for TINCR Gene

ENSEMBL proteins:

No data available for DME Specific Peptides for TINCR Gene

Domains & Families for TINCR Gene

Gene Families for TINCR Gene

Suggested Antigen Peptide Sequences for TINCR Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with TINCR: view

No data available for Protein Domains and UniProtKB/Swiss-Prot for TINCR Gene

Function for TINCR Gene

Phenotypes for TINCR Gene

genes like me logo Genes that share phenotypes with TINCR: view

Animal Model Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for TINCR Gene

Localization for TINCR Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for TINCR Gene

Pathways & Interactions for TINCR Gene

SuperPathways for TINCR Gene

No Data Available

Interacting Proteins for TINCR Gene

Gene Ontology (GO) - Biological Process for TINCR Gene


No data available for Pathways by source and SIGNOR curated interactions for TINCR Gene

Drugs & Compounds for TINCR Gene

No Compound Related Data Available

Transcripts for TINCR Gene

mRNA/cDNA for TINCR Gene

Unigene Clusters for TINCR Gene

Tissue differentiation-inducing non-protein coding RNA:
Representative Sequences:

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for TINCR Gene

No ASD Table

Relevant External Links for TINCR Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for TINCR Gene

mRNA expression in normal human tissues for TINCR Gene

mRNA differential expression in normal tissues according to GTEx for TINCR Gene

This gene is overexpressed in Skin - Sun Exposed (Lower leg) (x14.2), Skin - Not Sun Exposed (Suprapubic) (x12.8), and Esophagus - Mucosa (x5.0).

NURSA nuclear receptor signaling pathways regulating expression of TINCR Gene:


SOURCE GeneReport for Unigene cluster for TINCR Gene:

genes like me logo Genes that share expression patterns with TINCR: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for TINCR Gene

Orthologs for TINCR Gene

Evolution for TINCR Gene

Gene Tree for TINCR (if available)
Gene Tree for TINCR (if available)

No data available for Orthologs for TINCR Gene

Paralogs for TINCR Gene

No data available for Paralogs for TINCR Gene

Variants for TINCR Gene

Sequence variations from dbSNP and Humsavar for TINCR Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type
rs10451477 -- 5,560,801(+) GGCCT(C/G)AGAAG nc-transcript-variant
rs11085142 -- 5,557,938(+) GAGCG(A/G)GCAGG downstream-variant-500B
rs28594941 -- 5,568,603(+) CCAGC(A/C)CTTTG upstream-variant-2KB
rs28607963 -- 5,565,073(+) CTCGG(A/C)GTCAA intron-variant
rs34152404 -- 5,559,056(+) TTCAG(-/G)AACAT nc-transcript-variant

Structural Variations from Database of Genomic Variants (DGV) for TINCR Gene

Variant ID Type Subtype PubMed ID
esv3643529 CNV gain 21293372
nsv1062851 CNV gain 25217958

Relevant External Links for TINCR Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for TINCR Gene

Disorders for TINCR Gene

Relevant External Links for TINCR

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for TINCR Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for TINCR Gene

Publications for TINCR Gene

  1. Control of somatic tissue differentiation by the long non-coding RNA TINCR. (PMID: 23201690) Kretz M. … Khavari P.A. (Nature 2013) 2 3 65
  2. TINCR, staufen1, and cellular differentiation. (PMID: 24019000) Kretz M. (RNA Biol 2013) 2 3 65
  3. SP1-induced upregulation of the long noncoding RNA TINCR regulates cell proliferation and apoptosis by affecting KLF2 mRNA stability in gastric cancer. (PMID: 25728677) Xu T.P. … Shu Y.Q. (Oncogene 2015) 3 65
  4. A LncRNA-MAF:MAFB Transcription Factor Network Regulates Epidermal Differentiation. (PMID: 25805135) Lopez-Pajares V. … Khavari P.A. (Dev. Cell 2015) 3 65
  5. Pan-cancer transcriptome analysis reveals long noncoding RNAs with conserved function. (PMID: 25864709) Cabanski C.R. … Maher C.A. (RNA Biol 2015) 3 65

Products for TINCR Gene

Sources for TINCR Gene

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