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Aliases for TINCR Gene

Aliases for TINCR Gene

  • TINCR Ubiquitin Domain Containing 2 3
  • Tissue Differentiation-Inducing Non-Protein Coding RNA 2 3 5
  • Long Intergenic Non-Protein Coding RNA 36 2 3
  • Placenta-Specific 2 (Non-Protein Coding) 2 3
  • Terminal Differentiation-Induced NcRNA 2 3
  • Non-Protein Coding RNA 36 2
  • Placenta-Specific 2 2
  • Onco-LncRNA-16 3
  • NCRNA00036 3
  • LINC00036 3
  • PLAC2 3

External Ids for TINCR Gene

Previous HGNC Symbols for TINCR Gene

  • PLAC2

Summaries for TINCR Gene

Entrez Gene Summary for TINCR Gene

  • This gene produces a spliced long non-coding RNA that binds RNAs. This transcript interacts with staufen-1 protein to regulate the stability of mRNAs for genes involved in the differentiation of epidermal tissue. Variation in this gene may be associated with cancer progression. [provided by RefSeq, Aug 2017]

GeneCards Summary for TINCR Gene

TINCR (TINCR Ubiquitin Domain Containing) is a Protein Coding gene.

Additional gene information for TINCR Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TINCR Gene

Genomics for TINCR Gene

Regulatory Elements for TINCR Gene

Enhancers for TINCR Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH19H005567 0.9 Ensembl ENCODE 0.7 +0.1 133 0 CTCF MAZ SP3 KLF1 ZNF777 ZIC2 ZNF157 POLR2A GLIS1 KLF7 TINCR GC19M005554
GH19H005563 0.8 ENCODE 0.7 +3.8 3839 2 PKNOX1 SIN3A KLF17 BMI1 RAD21 ZNF121 ZNF366 FOS SMARCA5 ZNF280D KHSRP LONP1 RPL36 SNRPEP4 DUS3L RANBP3 GC19M005554 TINCR
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around TINCR on UCSC Golden Path with GeneCards custom track

Genomic Location for TINCR Gene

Chromosome:
19
Start:
5,558,167 bp from pter
End:
5,568,034 bp from pter
Size:
9,868 bases
Orientation:
Minus strand

Genomic View for TINCR Gene

Genes around TINCR on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TINCR Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TINCR Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TINCR Gene

Proteins for TINCR Gene

  • Protein details for TINCR Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    A0A1B0GTR7
    Recommended name:
    Tissue differentiation-inducing non-protein coding RNA
    Protein Accession:
    A0A1B0GTR7

    Protein attributes for TINCR Gene

    Size:
    56 amino acids
    Molecular mass:
    6469 Da
    Quaternary structure:
    No Data Available
  • Protein details for TINCR Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    A0A1B0GVN0
    Recommended name:
    Tissue differentiation-inducing non-protein coding RNA
    Protein Accession:
    A0A1B0GVN0

    Protein attributes for TINCR Gene

    Size:
    87 amino acids
    Molecular mass:
    10124 Da
    Quaternary structure:
    No Data Available

neXtProt entry for TINCR Gene

Post-translational modifications for TINCR Gene

No Post-translational modifications

Other Protein References for TINCR Gene

ENSEMBL proteins:

No data available for DME Specific Peptides for TINCR Gene

Domains & Families for TINCR Gene

Gene Families for TINCR Gene

Protein Domains for TINCR Gene

Suggested Antigen Peptide Sequences for TINCR Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with TINCR: view

No data available for UniProtKB/Swiss-Prot for TINCR Gene

Function for TINCR Gene

Phenotypes From GWAS Catalog for TINCR Gene

Phenotypes for TINCR Gene

genes like me logo Genes that share phenotypes with TINCR: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

Clone Products

  • Applied Biological Materials Clones for TINCR
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for TINCR Gene

Localization for TINCR Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for TINCR Gene

Pathways & Interactions for TINCR Gene

SuperPathways for TINCR Gene

No Data Available

Interacting Proteins for TINCR Gene

Gene Ontology (GO) - Biological Process for TINCR Gene

None

No data available for Pathways by source and SIGNOR curated interactions for TINCR Gene

Drugs & Compounds for TINCR Gene

No Compound Related Data Available

Transcripts for TINCR Gene

mRNA/cDNA for TINCR Gene

Unigene Clusters for TINCR Gene

Tissue differentiation-inducing non-protein coding RNA:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

  • Applied Biological Materials Clones for TINCR
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

Alternative Splicing Database (ASD) splice patterns (SP) for TINCR Gene

No ASD Table

Relevant External Links for TINCR Gene

GeneLoc Exon Structure for
TINCR
ECgene alternative splicing isoforms for
TINCR

Expression for TINCR Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for TINCR Gene

mRNA differential expression in normal tissues according to GTEx for TINCR Gene

This gene is overexpressed in Skin - Sun Exposed (Lower leg) (x14.2), Skin - Not Sun Exposed (Suprapubic) (x12.8), and Esophagus - Mucosa (x5.0).

NURSA nuclear receptor signaling pathways regulating expression of TINCR Gene:

TINCR

SOURCE GeneReport for Unigene cluster for TINCR Gene:

Hs.515575
genes like me logo Genes that share expression patterns with TINCR: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for TINCR Gene

Orthologs for TINCR Gene

Evolution for TINCR Gene

ENSEMBL:
Gene Tree for TINCR (if available)
TreeFam:
Gene Tree for TINCR (if available)

No data available for Orthologs for TINCR Gene

Paralogs for TINCR Gene

No data available for Paralogs for TINCR Gene

Variants for TINCR Gene

Sequence variations from dbSNP and Humsavar for TINCR Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type
rs1000107404 -- 5,562,748(+) CCAGA(C/T)TCAAG intron-variant
rs1000139312 -- 5,569,181(+) AAAAA(-/G)AAAGA upstream-variant-2KB
rs1000178061 -- 5,564,049(+) GACAA(A/C)CTGTC intron-variant
rs1000546238 -- 5,562,481(+) TATGT(A/G)CCAGG intron-variant
rs1000696305 -- 5,567,925(+) TCCAT(A/C/G)GCGCC nc-transcript-variant

Structural Variations from Database of Genomic Variants (DGV) for TINCR Gene

Variant ID Type Subtype PubMed ID
esv3643529 CNV gain 21293372
nsv1062851 CNV gain 25217958

Relevant External Links for TINCR Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
TINCR

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for TINCR Gene

Disorders for TINCR Gene

Relevant External Links for TINCR

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
TINCR

No disorders were found for TINCR Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for TINCR Gene

Publications for TINCR Gene

  1. Control of somatic tissue differentiation by the long non-coding RNA TINCR. (PMID: 23201690) Kretz M … Khavari PA (Nature 2013) 2 3 60
  2. TINCR, staufen1, and cellular differentiation. (PMID: 24019000) Kretz M (RNA biology 2013) 2 3 60
  3. The long noncoding RNA, TINCR, functions as a competing endogenous RNA to regulate PDK1 expression by sponging miR-375 in gastric cancer. (PMID: 28744139) Chen Z … Hu J (OncoTargets and therapy 2017) 3 60
  4. E2F1 induces TINCR transcriptional activity and accelerates gastric cancer progression via activation of TINCR/STAU1/CDKN2B signaling axis. (PMID: 28569791) Xu TP … Shu YQ (Cell death & disease 2017) 3 60
  5. LncRNA TINCR attenuates cardiac hypertrophy by epigenetic silencing of CaMKII. (PMID: 28548932) Shao M … Zhuo C (Oncotarget 2017) 3 60

Products for TINCR Gene

Sources for TINCR Gene

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