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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

TINAGL1 Gene

protein-coding   GIFtS: 51
GCID: GC01P032042

tubulointerstitial nephritis antigen-like 1

(Previous names: lipocalin 7, TINAG-like 1 )
(Previous symbol: LCN7)
 Explore 8 diseases affiliated with
TINAGL1 via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for TINAGL1    

Aliases
for TINAGL1 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Tubulointerstitial Nephritis Antigen-Like 11 2     OLRG-22 3
LCN71 2 3     TIN-Ag-RP2 3
ARG11 2     TIN Ag-Related Protein2 3
LIECG31 2     Androgen-Regulated Gene 12
P3ECSL1 2     Oxidized-LDL Responsive Gene 22
TINAGRP1 2     Tubulointerstitial Nephritis Antigen-Like2
Lipocalin 71 2     GIS53
TINAG-Like 11 2     OLRG23
Glucocorticoid-Inducible Protein 52 3     TINAGL3
Tubulointerstitial Nephritis Antigen-Related Protein2 3     Oxidized LDL-Responsive Gene 2 Protein3

External Ids:    HGNC: 191681   Entrez Gene: 641292   Ensembl: ENSG000001429107   UniProtKB: Q9GZM73   

Export aliases for TINAGL1 gene to outside databases

Previous GC identifers: GC01P031712 GC01P031814 GC01P030159


Summaries
for TINAGL1 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for TINAGL1:
The protein encoded by this gene is similar in sequence to tubulointerstitial nephritis antigen, a secreted
glycoprotein that is recognized by antibodies in some types of immune-related tubulointerstitial nephritis. Three
transcript variants encoding different isoforms have been found for this gene. (provided by RefSeq, Feb 2011)

UniProtKB/Swiss-Prot: TINAL_HUMAN, Q9GZM7
Function: May be implicated in the adrenocortical zonation and in mechanisms for repressing the CYP11B1 gene expression
in adrenocortical cells. This is a non catalytic peptidase C1 family protein (By similarity)

Gene Wiki entry for TINAGL1


Genomic Views
for TINAGL1 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000001.10  NC_018912.1  NT_032977.9  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the TINAGL1 gene promoter:
         FOXF2   HTF   STAT5A   E4BP4   GATA-2   RORalpha1   FOXO4   STAT3   ZIC2/Zic2   TGIF   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: TINAGL1 promoter sequence
   Search SABiosciences Chromatin IP Primers for TINAGL1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TINAGL1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1p35.2   Ensembl cytogenetic band:  1p35.2   HGNC cytogenetic band: 1p34.3

TINAGL1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TINAGL1 gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01P032042:  view genomic region     (about GC identifiers)

Start:
 32,042,086 bp from pter      End:
 32,053,288 bp from pter
Size:
 11,203 bases      Orientation:
 plus strand

Proteins
for TINAGL1 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: TINAL_HUMAN, Q9GZM7 (See protein sequence)
Recommended Name: Tubulointerstitial nephritis antigen-like precursor  
Size: 467 amino acids; 52387 Da
Subcellular location: Secreted
Sequence caution: Sequence=AAH09048.1; Type=Erroneous initiation; Sequence=BAB55403.1; Type=Erroneous initiation;
Secondary accessions: A8K9Q5 B4DPK6 D3DPN8 Q8TEJ9 Q8WZ23 Q96GZ4 Q96JW3
Alternative splicing: 3 isoforms:  Q9GZM7-1   Q9GZM7-2   Q9GZM7-3   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for TINAGL1: NX_Q9GZM7

Post-translational modifications:

  • Glycosylated1
  • View neXtProt modification sites for NX_Q9GZM7

    • TINAGL1 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins (3 alternative transcripts): 
    NP_001191343.1  NP_001191344.1  NP_071447.1  

    ENSEMBL proteins: 
     ENSP00000271064   ENSP00000395137   ENSP00000445392   ENSP00000411798  

    Human Recombinant Protein Products: 
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    Uscn Proteins for TINAGL1

    Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005576extracellular region NAS11170462
    GO:0005615extracellular space ISS--
    GO:0005737cytoplasm IEA--
    GO:0031012colocalizes with extracellular matrix IDA--


    TINAGL1 for ontologies           About GeneDecksing



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    Uscn ELISAs and CLIAs for TINAGL1

    Protein Domains /
    Families
    for TINAGL1 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    TINAGL1 for domains           About GeneDecksing

    4 InterPro domains/families:
     IPR013128 Peptidase_C1A
     IPR025660 Pept_his_AS
     IPR000668 Peptidase_C1A_C
     IPR001212 Somatomedin_B_dom

    Graphical View of Domain Structure for InterPro Entry Q9GZM7

    ProtoNet protein and cluster: Q9GZM7

    1 Blocks protein family: IPB000668 Papain cysteine protease (C1) family signature

    UniProtKB/Swiss-Prot: TINAL_HUMAN, Q9GZM7
    Similarity: Belongs to the peptidase C1 family
    Similarity: Contains 1 SMB (somatomedin-B) domain


    Function
    for TINAGL1 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: TINAL_HUMAN, Q9GZM7
    Function: May be implicated in the adrenocortical zonation and in mechanisms for repressing the CYP11B1 gene expression
    in adrenocortical cells. This is a non catalytic peptidase C1 family protein (By similarity)

    miRNA
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    SwitchGear 3'UTR luciferase reporter plasmid: TINAGL1 3' UTR sequence
    Inhib. RNA
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    Gene Editing
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    Clone
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    LifeMap BioReagents: cell line associated with TINAGL1: PureStem ES-210, Ecto-ntu Progenitor

    In Situ Assay
    Products:       
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    Gene Ontology (GO): 5 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005044scavenger receptor activity IEA--
    GO:0005201extracellular matrix structural constituent NAS11170462
    GO:0008234cysteine-type peptidase activity IEA--
    GO:0030247polysaccharide binding IEA--
    GO:0043236laminin binding IEA--


    TINAGL1 for ontologies           About GeneDecksing


    Animal Models:
         Mouse knock-out Tinagl1tm1Lex for TINAGL1
         1 MGI phenotypic allele for Tinagl1 (no phenotypes)

    TINAGL1 for phenotypes           About GeneDecksing


    Pathways & Interactions
    for TINAGL1 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for TINAGL1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 6)

    5/11 Interacting proteins for TINAGL1 (Q9GZM72, 3 ENSP000002710644) via UniProtKB, MINT, STRING, and/or I2D (see all 11)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    LMO4P619682, 3, ENSP000003595734MINT-60894 I2D: score=3 STRING: ENSP00000359573
    MED31Q9Y3C72, 3MINT-65403 I2D: score=5 
    UTP14AQ9BVJ62, 3MINT-65402 I2D: score=5 
    SMAD9O151982, 3, ENSP000003691544MINT-62060 I2D: score=3 STRING: ENSP00000369154
    MDFIQ997502, 3, ENSP000002303214MINT-67389 I2D: score=5 STRING: ENSP00000230321
    About this table

    Gene Ontology (GO): 3 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006508proteolysis IEA--
    GO:0006955immune response IEA--
    GO:0016197endosomal transport TAS10799322


    TINAGL1 for ontologies           About GeneDecksing



    Drugs & Compounds
    for TINAGL1 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    TINAGL1 for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for TINAGL1
    2 Novoseek chemical compound relationships for TINAGL1 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    arachidonic acid 24.8 1 2143470 (1)
    cysteine 16.4 1 15195995 (1)

    Search CenterWatch for drugs/clinical trials and news about TINAGL1 / TINAL 

    Transcripts
    for TINAGL1 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for TINAGL1 gene (3 alternative transcripts): 
    NM_001204414.1  NM_001204415.1  NM_022164.2  

    Unigene Cluster for TINAGL1:

    Tubulointerstitial nephritis antigen-like 1
    Hs.199368  [show with all ESTs]
    Unigene Representative Sequence: AK128451
    13 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000476960 ENST00000271064(uc001bta.3 uc021oko.1) ENST00000461030
    ENST00000466998 ENST00000478398 ENST00000481165(uc010ogk.1) ENST00000468635
    ENST00000498429 ENST00000463112 ENST00000480586 ENST00000457433(uc010ogj.2)
    ENST00000537531 ENST00000441210(uc010ogi.1)

    miRNA
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    hsa-miR-4283 hsa-miR-185* hsa-miR-566 hsa-miR-450b-3p hsa-miR-9 hsa-miR-637 hsa-miR-3151 hsa-miR-30b*
    SwitchGear 3'UTR luciferase reporter plasmid: TINAGL1 3' UTR sequence
    Inhib. RNA
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    Clone
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    Primer
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    Additional cDNA sequence: 

    AB050716.1 AF205436.1 AF236150.1 AK027839.1 AK075398.1 AK128451.1 AK292770.1 AK296322.1 
    AK298382.1 AY358421.1 BC009048.1 BC064633.1 HM016160.1 HM016161.1 

    22 DOTS entries:

    DT.422155  DT.100874963  DT.100874968  DT.100802912  DT.100803505  DT.100764098  DT.121371351  DT.99986408 
    DT.91979496  DT.121371414  DT.100874952  DT.100874956  DT.121371291  DT.121371304  DT.121371350  DT.75179546 
    DT.91671691  DT.91741226  DT.100833503  DT.121371410  DT.92043384  DT.97859640 

    24/92 AceView cDNA sequences (see all 92):

    BM923842 CB106240 BM761000 BX337515 BM843928 CR596614 BG985052 CA487392 
    BX283995 BM763831 BQ690538 AK074124 BE902304 BM053143 AF289569 BE744387 
    AI439381 BX359073 BX390615 BU543655 BM764416 BX458628 BM847376 BE744532 

    GeneLoc Exon Structure

    5/11 Alternative Splicing Database (ASD) splice patterns (SP) for TINAGL1 (see all 11)    About this scheme

    ExUns: 1a · 1b · 1c ^ 2a · 2b · 2c ^ 3 ^ 4a · 4b ^ 5 ^ 6 ^ 7a · 7b ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13a · 13b ^ 14 ^ 15a · 15b · 15c
    SP1:                    -     -           -     -           -     -                                                     -                           
    SP2:                    -     -     -     -     -           -     -                                                                                 
    SP3:                                            -           -     -                                                                                 
    SP4:                                                              -                                                                                 
    SP5:                                                                                                              -     -                           


    ECgene alternative splicing isoforms for TINAGL1

    Expression
    for TINAGL1 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TINAGL1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: GGTCATCACT

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    TINAGL1 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    1 LifeMap In Vivo Development Anatomical Compartment/Cell 
    Tissue Anatomical Compartment CellCategory (developmental path)
    BrainChoroid PlexusBrain
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization
    Stem Cell Differentiation: 3 LifeMap Cells 
    NameCategory
    PureStem™ endothelial progenitor 30-SM2-1 (Embryonic Progenitor Cell)Endothelium
    PureStem™ endothelial progenitor RP1-MV2-18 (Embryonic Progenitor Cell)Endothelium
    PureStem™ endothelial progenitor 30-MV2-14 (Embryonic Progenitor Cell)Endothelium

    See TINAGL1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for TINAGL1

    SOURCE GeneReport for Unigene cluster: Hs.199368

    UniProtKB/Swiss-Prot: TINAL_HUMAN, Q9GZM7
    Tissue specificity: Highly expressed in aorta, heart, placenta, kidney and a colorectal adenocarcinoma cell line.
    Moderately expressed in skeletal muscle, pancreas, lung, lymph nodes, adrenal gland, bone marrow and thyroid. Weakly
    expressed in colon, small intestine, ovary, spleen, testis and prostate. Predominantly found in vascular smooth muscle
    cells, but also in cardiac and skeletal muscle cells as well as kidney

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    In Situ
    Assay Products:     
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    Orthologs
    for TINAGL1 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of animals.

    Orthologs for TINAGL1 gene from 5/16 species (see all 16)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    chicken
    (Gallus gallus)    		 Aves TINAGL11 tubulointerstitial nephritis antigen-like 1 72.3(n)
    68.64(a)    		   430648  XM_428202.3  XP_428202.3 
    lizard
    (Anolis carolinensis)    		 Reptilia TINAGL16
    		 --
    		 68(a)
    		 1 ↔ 1
    		 GL343308.1(387877-417327)
    zebrafish
    (Danio rerio)    		 Actinopterygii tinagl11 tubulointerstitial nephritis antigen-like 1 65.1(n)
    64.73(a)    		   562116  NM_001044977.2  NP_001038442.2 
    fruit fly
    (Drosophila melanogaster)    		 Insecta CG30741 CG3074 54.33(n)
    46.02(a)    		   37537  NM_166519.1  NP_726176.1 
    worm
    (Caenorhabditis elegans)    		 Secernentea F26E4.31 Protein F26E4.3 48.11(n)
    47.29(a)    		   172827  NM_060192.5  NP_492593.2 


    ENSEMBL Gene Tree for TINAGL1 (if available)
    TreeFam Gene Tree for TINAGL1 (if available) 

    Paralogs
    for TINAGL1 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for TINAGL1 gene
    TINAG2  CTSL12  CTSF2  CTSO2  CTSW2  CTSK2  CTSB2  CTSL22  
    CTSS2  CTSH2  CTSC2  CTSZ2  
    1 SIMAP similar gene for TINAGL1 using alignment to 3 protein entries:     TINAL_HUMAN (see all proteins):
    TINAG

    TINAGL1 for paralogs           About GeneDecksing



    Genomic Variants
    for TINAGL1 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/309 NCBI SNPs in TINAGL1 are shown (see all 309)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 1 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs1859409241,2
    		--32040097(+) ACAGGC/TAAACA 2 -- us2k10--------
    rs1924681271,2
    		--32040119(+) GCCAAA/GGCAGG 2 -- us2k10--------
    rs1837862531,2
    		--32040232(+) CACCTA/GTAGTC 2 -- us2k10--------
    rs1117238021,2
    		C,--32040264(+) GTGGGA/GGGATT 2 -- us2k12Minor allele frequency- G:0.16NA EA 122
    rs1502903301,2
    		--32040265(+) TGGGAA/GGATTA 2 -- us2k10--------
    rs1380977231,2
    		--32040266(+) GGGAGG/TATTAC 2 -- us2k10--------
    rs109144441,2
    		F,H,--32040296(+) GCTTCA/GGTGAG 2 -- us2k15Minor allele frequency- G:0.01NS EA WA 532
    rs1142969721,2
    		F,--32040309(+) GAGATC/TGCGCC 2 -- us2k11Minor allele frequency- T:0.06NA 120
    rs1491020131,2
    		--32040433(+) AGAAAC/TACCCC 2 -- us2k10--------
    rs1875923081,2
    		--32040504(+) ACTCAC/TGAGGG 2 -- us2k10--------

    HapMap Linkage Disequilibrium report for TINAGL1 (32042086 - 32053288 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 3 variations for TINAGL1
         3 CNVs: 30382 2304 3287

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    Disorders / Diseases
    for TINAGL1 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    TINAGL1 for disorders           About GeneDecksing

    8 diseases for TINAGL1:    About MalaCards
    nephritis    open-angle glaucoma    glaucoma    craniosynostosis
    thyroiditis    adenocarcinoma    malaria    prostatitis

    1 Novoseek disease relationship for TINAGL1 gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    inflammation 15.2 1 15962097 (1)


    Export disorders for TINAGL1 gene to outside databases

    Publications
    for TINAGL1 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for TINAGL1 gene, integrated from 9 sources (see all 33):
    (articles sorted by number of sources associating them with TINAGL1)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. TIN-ag-RP, a novel catalytically inactive cathepsin B-related protein with EGF domains, is predominantly expressed in vascular smooth muscle cells. (PubMed id 11170462)1, 2, 3, 9 Wex T.... Broemme D. (2001)
    2. Signal sequence and keyword trap in silico for selection of full- length human cDNAs encoding secretion or membrane proteins from oligo- capped cDNA libraries. (PubMed id 16303743)1, 2 Otsuki T....Isogai T. (2005)
    3. Large-scale cDNA transfection screening for genes related to cancer development and progression. (PubMed id 15498874)1, 2 Wan D....Gu J. (2004)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    5. Signal peptide prediction based on analysis of experimentally verified cleavage sites. (PubMed id 15340161)1, 2 Zhang Z. and Henzel W.J. (2004)
    6. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    7. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)1, 2 Clark H.F.... Gray A.M. (2003)
    8. Cloning, characterization, and expression of the human TIN-ag-RP gene encoding a novel putative extracellular matrix protein. (PubMed id 10799322)1, 2 Broemme N.C.... Broemme D. (2000)
    9. Interaction of human papillomavirus type 16 L2 with cellular proteins: identification of novel nuclear body-associated proteins. (PubMed id 12482659)1, 9 Goernemann J.... Mueller M. (2002)
    10. Dynamics of cullin-RING ubiquitin ligase network revea led by systematic quantitative proteomics. (PubMed id 21145461)1 Bennett E.J....Harper J.W. (2010)

    External Searches for TINAGL1 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Disorders
    Free Text  
      Query String
    		PubMed
    OMIM
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      (Note: In FireFox, select the above section and copy using Ctrl-C)

    Genome Databases showing TINAGL1 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 64129 HGNC: 19168 AceView: LCN7 Ensembl:ENSG00000142910 euGenes: HUgn64129
    ECgene: TINAGL1 H-InvDB: TINAGL1

    Other Databases showing TINAGL1 gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing TINAGL1 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for TINAGL1 Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for TINAGL1 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for TINAGL1 gene:
    Search GeneIP for patents involving TINAGL1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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     TINAGL1 Proteins, Antibodies, CLIAs, and ELISAs
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