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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

TINAG Gene

protein-coding   GIFtS: 53
GCID: GC06P054220

tubulointerstitial nephritis antigen
 Explore 6 diseases affiliated with
TINAG via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for TINAG    

Aliases
for TINAG gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Tubulointerstitial Nephritis Antigen1 2
TIN-AG2
TIN-Ag3
TIN15
TIN25

External Ids:    HGNC: 145991   Entrez Gene: 272832   Ensembl: ENSG000001372517   OMIM: 6067495   UniProtKB: Q9UJW23   

Export aliases for TINAG gene to outside databases

Previous GC identifers: GC06P054175 GC06P054281 GC06P054006


Summaries
for TINAG gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for TINAG:
This gene encodes a glycoprotein that is restricted within the kidney to the basement membranes underlying the
epithelium of Bowman's capsule and proximal and distal tubules. Autoantibodies against this protein are found in sera
of patients with tubulointerstital nephritis, membranous nephropathy and anti-glomerular basement membrane nephritis.
Ontogeny studies suggest that the expression of this antigen is developmentally regulated in a precise spatial and
temporal pattern throughout nephrogenesis. (provided by RefSeq, Nov 2011)

UniProtKB/Swiss-Prot: TINAG_HUMAN, Q9UJW2
Function: Mediates adhesion of proximal tubule epithelial cells via integrins alpha3-beta1 and alphaV-beta3. This is a
non catalytic peptidase C1 family protein

Gene Wiki entry for TINAG


Genomic Views
for TINAG gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000006.11  NC_018917.1  NT_007592.15  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the TINAG gene promoter:
         TBP   STAT5A   POU6F1 (c2)   YY1   MEF-2A   POU2F1   POU2F1a   SEF-1 (1)   Cart-1   aMEF-2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: TINAG promoter sequence
   Search SABiosciences Chromatin IP Primers for TINAG

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TINAG


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 6p12.1   Ensembl cytogenetic band:  6p12.1   HGNC cytogenetic band: 6p12.1

TINAG Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TINAG gene location

GeneLoc information about chromosome 6         GeneLoc Exon Structure

GeneLoc location for GC06P054220:  view genomic region     (about GC identifiers)

Start:
 54,172,657 bp from pter      End:
 54,254,950 bp from pter
Size:
 82,294 bases      Orientation:
 plus strand

Proteins
for TINAG gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: TINAG_HUMAN, Q9UJW2 (See protein sequence)
Recommended Name: Tubulointerstitial nephritis antigen  
Size: 476 amino acids; 54605 Da
Subcellular location: Secreted, extracellular space, extracellular matrix, basement membrane
Developmental stage: Initially observed in the Bowman capsule during early glomerular capillary loop formation in the
kidney. In more developmentally mature glomeruli, following transition from early to mid-capillary loop stage,
expression is higher in the proximal tubular basement membrane than in the distal basement membrane and Bowman capsule
Miscellaneous: Antibodies against TINAG are found in sera of patients with tubulointerstitial nephritis, a rare
autoimmune disorder that causes acute and chronic renal injury
Secondary accessions: Q5T467 Q9UJW1 Q9ULZ4
Alternative splicing: 2 isoforms:  Q9UJW2-1   Q9UJW2-2   (Major isoform)

Explore the universe of human proteins at neXtProt for TINAG: NX_Q9UJW2

Post-translational modifications:

  • It has been suggested that the active SMB domain may be permitted considerable disulfide bond heterogeneity or
    • variability, thus 2 alternate disulfide patterns based on 3D structures are described with 1 disulfide bond conserved
    in both1
  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q9UJW2

    • TINAG Protein expression data from MOPED and PaxDb:    About this image 
    TINAG Protein Expression
    REFSEQ proteins: NP_055279.3  
    ENSEMBL proteins: 
     ENSP00000359906   ENSP00000259782   ENSP00000359902   ENSP00000359901  

    Human Recombinant Protein Products for TINAG: 
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    OriGene Protein Over-expression Lysate: TINAG
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    Novus Biologicals TINAG Proteins
    Novus Biologicals TINAG Lysates
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins
    Uscn Proteins for TINAG

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005604basement membrane IDA1762287

    TINAG for ontologies           About GeneDecksing



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    Uscn ELISAs and CLIAs for TINAG

    Protein Domains /
    Families
    for TINAG gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    TINAG for domains           About GeneDecksing

    4 InterPro domains/families:
     IPR013128 Peptidase_C1A
     IPR025661 Pept_asp_AS
     IPR000668 Peptidase_C1A_C
     IPR001212 Somatomedin_B_dom

    Graphical View of Domain Structure for InterPro Entry Q9UJW2

    ProtoNet protein and cluster: Q9UJW2

    1 Blocks protein family: IPB000668 Papain cysteine protease (C1) family signature

    UniProtKB/Swiss-Prot: TINAG_HUMAN, Q9UJW2
    Similarity: Belongs to the peptidase C1 family
    Similarity: Contains 1 SMB (somatomedin-B) domain


    Function
    for TINAG gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, Sirion Biotech, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, Sirion Biotech, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Molecular Function:

         UniProtKB/Swiss-Prot Summary: TINAG_HUMAN, Q9UJW2
    Function: Mediates adhesion of proximal tubule epithelial cells via integrins alpha3-beta1 and alphaV-beta3. This is a
    non catalytic peptidase C1 family protein

         Gene Ontology (GO): 5 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000166nucleotide binding TAS10652240
    GO:0004197cysteine-type endopeptidase activity TAS10652240
    GO:0005044scavenger receptor activity IEA--
    GO:0008234cysteine-type peptidase activity ----
    GO:0030247polysaccharide binding IEA--
         
    TINAG for ontologies           About GeneDecksing


    Phenotypes:
         1 MGI phenotypic allele for Tinag (no phenotypes)

    TINAG for phenotypes           About GeneDecksing

    Animal Models:
         Mouse knock-out Tinagtm1Lex for TINAG
       inGenious Targeting Laboratory - Customizable classic, inducible, and humanized mouse model solutions for TINAG 

    miRNA
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    Browse MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat TINAG
    Search QIAGEN for miScript miRNA Assays for microRNAs that regulate TINAG
    SwitchGear 3'UTR luciferase reporter plasmid: TINAG 3' UTR sequence
    Inhib. RNA
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    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for TINAG (see all 7)
    OriGene shRNA RFP: TINAG
    OriGene siRNA: TINAG
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    Sirion Biotech Custom design and validation of potent shRNA sequences against TINAG 

    Gene Editing
    Products:    		DNA2.0 Custom Protein Engineering Service for TINAG
    Sirion Biotech Customized adenovirus for overexpression of TINAG 
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    Clone
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    OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TINAG (see all 3)
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    Cell Line
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    In Situ Assay
    Products:       
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TINAG


    Pathways & Interactions
    for TINAG gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for TINAG

    STRING Interaction Network Preview (showing 3 interactants - click image to see more details)

    3 Interacting proteins for TINAG (Q9UJW23 ENSP000002597824) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    TERF1P542743, ENSP000002766034I2D: score=1 STRING: ENSP00000276603
    CPB2ENSP000001813834STRING: ENSP00000181383
    TMEM45BENSP000002814414STRING: ENSP00000281441
    About this table

    Gene Ontology (GO): 4 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006508proteolysis IEA--
    GO:0006955immune response IEA--
    GO:0007155cell adhesion IDA8770961
    GO:0007443Malpighian tubule morphogenesis ----

    TINAG for ontologies           About GeneDecksing



    Drugs & Compounds
    for TINAG gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    TINAG for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for TINAG
    1 Novoseek chemical compound relationship for TINAG gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    cysteine 36.4 2 10652240 (1), 10752525 (1)

    Search CenterWatch for drugs/clinical trials and news about TINAG 

    Transcripts
    for TINAG gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, Sirion Biotech, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for TINAG gene: 
    NM_014464.3  

    Unigene Cluster for TINAG:

    Tubulointerstitial nephritis antigen
    Hs.127011  [show with all ESTs]
    Unigene Representative Sequence: BC056235
    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000486436 ENST00000370869 ENST00000259782(uc003pci.3 uc003pcj.2 uc010jzt.2)
    ENST00000370865 ENST00000370864

    miRNA
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    SwitchGear 3'UTR luciferase reporter plasmid: TINAG 3' UTR sequence
    Inhib. RNA
    Products:             		Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for TINAG (see all 7)
    OriGene shRNA RFP: TINAG
    OriGene siRNA: TINAG
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TINAG
    Sirion Biotech Custom design and validation of potent shRNA sequences against TINAG 
    Clone
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    OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TINAG (see all 2)
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    GenScript: all cDNA clones in your preferred vector: TINAG (NM_014464)
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    Primer
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TINAG
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TINAG

    Additional cDNA sequence: 

    AB022277.1 AF195116.1 AF195117.1 AK312918.1 BC056235.1 BC070278.1 

    5 DOTS entries:

    DT.40126748  DT.91744224  DT.91744226  DT.121321973  DT.75102042 

    24/65 AceView cDNA sequences (see all 65):

    BC056235 AI245487 AA934831 BM857019 BX118861 BF434442 AI241144 AI479548 
    AW027949 AA327564 BF591880 AI253049 AI627942 BM794563 AB022277 BG427401 
    NM_014464 BI765216 AI949653 AL698332 AW139886 AW772244 BV205467 BM795244 

    GeneLoc Exon Structure

    5 Alternative Splicing Database (ASD) splice patterns (SP) for TINAG    About this scheme

    ExUns: 1 ^ 2 ^ 3a · 3b · 3c ^ 4 ^ 5a · 5b ^ 6a · 6b ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12a · 12b ^ 13 ^ 14a · 14b
    SP1:                                            -                                                           -               
    SP2:        -     -     -                       -                                                                           
    SP3:              -     -                                                                                                   
    SP4:                                                                                                                        
    SP5:                                                                                                                        


    ECgene alternative splicing isoforms for TINAG

    Expression
    for TINAG gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TINAG expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: --
    TINAG Expression
    About this image

    TINAG expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table

    3 LifeMap In Vivo Development Anatomical Compartments/Cells 
    Tissue Anatomical Compartment CellCategory (developmental path)
    Skeletal MuscleHyoid Arch MusclesMuscle Progenitor CellsSkeletal Muscle
    Skeletal MuscleMandibular Arch MusclesMuscle Progenitor CellsSkeletal Muscle
    TestisSeminiferous TubulesSertoli cellsTestis
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization

    See TINAG Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for TINAG

    SOURCE GeneReport for Unigene cluster: Hs.127011

    UniProtKB/Swiss-Prot: TINAG_HUMAN, Q9UJW2
    Tissue specificity: Expressed in the kidney cortex, small intestine and cornea

        SABiosciences Custom PCR Arrays for TINAG
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    In Situ
    Assay Products:     
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TINAG

    Orthologs
    for TINAG gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of animals.

    Orthologs for TINAG gene from 4/14 species (see all 14)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    chicken
    (Gallus gallus)    		 Aves TINAG1 tubulointerstitial nephritis antigen 62.82(n)
    55.99(a)    		   421888  XM_419905.3  XP_419905.3 
    lizard
    (Anolis carolinensis)    		 Reptilia TINAG6
    		 --
    		 54(a)
    		 1 ↔ 1
    		 GL343342.1(244494-297600)
    fruit fly
    (Drosophila melanogaster)    		 Insecta CG30743 cathepsin B 39(a)   58C7   --
    worm
    (Caenorhabditis elegans)    		 Secernentea F26E4.33 cysteine protease 41(a)   I(9770626-9775999)   --


    ENSEMBL Gene Tree for TINAG (if available)
    TreeFam Gene Tree for TINAG (if available) 

    Paralogs
    for TINAG gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for TINAG gene
    CTSL12  CTSF2  CTSO2  CTSW2  CTSK2  CTSB2  CTSL22  CTSS2  
    CTSH2  CTSC2  TINAGL12  CTSZ2  
    3 SIMAP similar genes for TINAG using alignment to 6 protein entries:     TINAG_HUMAN (see all proteins):
    TINAGL1    CTSB    DKFZp686B24257

    TINAG for paralogs           About GeneDecksing



    Genomic Variants
    for TINAG gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/1706 NCBI SNPs in TINAG are shown (see all 1706)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 6 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs1932268031,2
    		--54171284(+) ATTTCA/GAATGA 1 -- us2k10--------
    rs1839492751,2
    		--54171315(+) TGAATC/TCAAAA 1 -- us2k10--------
    rs1459473621,2
    		--54171344(+) AGCATA/TGTGAA 1 -- us2k10--------
    rs1877183391,2
    		--54171395(+) CAAGGA/GAGGAA 1 -- us2k10--------
    rs1397969731,2
    		--54171417(+) TAGTGA/GGTATG 1 -- us2k10--------
    rs1148371891,2
    		F--54171457(+) CATGTG/TTGATG 1 -- us2k11Minor allele frequency- T:0.07WA 118
    rs1422275671,2
    		--54171486(+) ATTATC/GGCATT 1 -- us2k10--------
    rs1923456931,2
    		--54171503(+) TCCCAC/TCCATC 1 -- us2k10--------
    rs1841747701,2
    		--54171608(+) GCAGAA/TCTAGG 1 -- us2k10--------
    rs37568081,2
    		C,F,A,H--54171624(-) CTAATG/AGAATT 1 -- us2k121Minor allele frequency- A:0.46NS EA NA CSA WA 2348

    HapMap Linkage Disequilibrium report for TINAG (54172657 - 54254950 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 1 variation for TINAG
         1 Indel: 59347
    Human Gene Mutation Database (HGMD): TINAG

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    Disorders / Diseases
    for TINAG gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    TINAG for disorders           About GeneDecksing

    OMIM gene information: 606749    OMIM disorders: --

    6 diseases for TINAG:    About MalaCards
    nephritis    nephropathy    renal carcinoma    fibrosis
    carcinoma    malaria

    2 diseases from the University of Copenhagen DISEASES database for TINAG:
    Nephronophthisis     Nephritis

    3 Novoseek disease relationships for TINAG gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    tubulointerstitial nephritis 95.1 36 7608193 (2), 9643646 (2), 8770961 (2), 19297554 (2) (see all 16)
    nephritis 57.6 1 1466368 (1)
    nephropathy membranous 55.6 1 1466368 (1)

    Human Genome Epidemiology (HuGE) Navigator: TINAG (1 document)

    Export disorders for TINAG gene to outside databases

    Publications
    for TINAG gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for TINAG gene, integrated from 9 sources (see all 25):
    (articles sorted by number of sources associating them with TINAG)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. Molecular cloning, expression, and chromosomal localization of a human tubulointerstitial nephritis antigen. (PubMed id 10652240)1, 2, 3, 9 Ikeda M.... Yoshioka K. (2000)
    2. Identification of two alternatively spliced forms of human tubulointerstitial nephritis antigen (TIN-Ag). (PubMed id 10752525)1, 2, 9 Zhou B....Charonis A.S. (2000)
    3. Tubulointerstitial nephritis antigen (TIN-ag) is expressed in distinct segments of the developing human nephron. (PubMed id 9643646)1, 2, 9 Nelson T.R.... Charonis A.S. (1998)
    4. Receptors in proximal tubular epithelial cells for tubulointerstitial nephritis antigen. (PubMed id 8770961)1, 2, 9 Chen Y.... Charonis A.S. (1996)
    5. Role of antibodies to tubulointerstitial nephritis antigen in human anti-tubular basement membrane nephritis associated with membranous nephropathy. (PubMed id 1466368)1, 2, 9 Katz A....Butkowski R.J. (1992)
    6. Distribution of tubulointerstitial nephritis antigen and evidence for multiple forms. (PubMed id 1762287)1, 2, 9 Butkowski R.J.... Fish A.J. (1991)
    7. Identification of a target antigen in human anti-tubular basement membrane nephritis. (PubMed id 3553704)1, 2 Fliger F.D....Butkowski R.J. (1987)
    8. A tubulointerstitial nephritis antigen gene defect ca uses childhood-onset chronic renal failure. (PubMed id 20157734)1, 9 Takemura Y....Takemura T. (2010)
    9. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1 Rose J.E....Uhl G.R. (2010)
    10. Radiation pharmacogenomics: a genome-wide association approach to identify radiation response biomarkers using human lymphoblastoid cell lines. (PubMed id 20923822)1 Niu N....Wang L. (2010)

    External Searches for TINAG gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
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    Genome Databases showing TINAG gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 27283 HGNC: 14599 AceView: TINAG Ensembl:ENSG00000137251 euGenes: HUgn27283
    ECgene: TINAG H-InvDB: TINAG

    Other Databases showing TINAG gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing TINAG gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for TINAG Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for TINAG gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for TINAG gene:
    Search GeneIP for patents involving TINAG

    GeneCards and IP:
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