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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

TINAG Gene

protein-coding   GIFtS: 54
GCID: GC06P054220

Tubulointerstitial Nephritis Antigen

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Tubulointerstitial Nephritis Antigen1 2
TIN-AG2
TIN-Ag3
TIN15
TIN25

External Ids:    HGNC: 145991   Entrez Gene: 272832   Ensembl: ENSG000001372517   OMIM: 6067495   UniProtKB: Q9UJW23   

Export aliases for TINAG gene to outside databases

Previous GC identifers: GC06P054175 GC06P054281 GC06P054006


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for TINAG Gene:
This gene encodes a glycoprotein that is restricted within the kidney to the basement membranes underlying the
epithelium of Bowman's capsule and proximal and distal tubules. Autoantibodies against this protein are found in
sera of patients with tubulointerstital nephritis, membranous nephropathy and anti-glomerular basement membrane
nephritis. Ontogeny studies suggest that the expression of this antigen is developmentally regulated in a precise
spatial and temporal pattern throughout nephrogenesis. (provided by RefSeq, Nov 2011)

GeneCards Summary for TINAG Gene: 
TINAG (tubulointerstitial nephritis antigen) is a protein-coding gene. Diseases associated with TINAG include nephritis, and nephronophthisis. GO annotations related to this gene include scavenger receptor activity and nucleotide binding. An important paralog of this gene is CTSF.

UniProtKB/Swiss-Prot: TINAG_HUMAN, Q9UJW2
Function: Mediates adhesion of proximal tubule epithelial cells via integrins alpha3-beta1 and alphaV-beta3. This
is a non catalytic peptidase C1 family protein

Gene Wiki entry for TINAG Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000006.11  NC_018917.2  NT_007592.15  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the TINAG gene promoter:
         TBP   STAT5A   POU6F1 (c2)   YY1   MEF-2A   POU2F1   POU2F1a   SEF-1 (1)   Cart-1   aMEF-2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidTINAG promoter sequence
   Search SABiosciences Chromatin IP Primers for TINAG

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TINAG


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 6p12.1   Ensembl cytogenetic band:  6p12.1   HGNC cytogenetic band: 6p12.1

TINAG Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TINAG gene location

GeneLoc information about chromosome 6         GeneLoc Exon Structure

GeneLoc location for GC06P054220:  view genomic region     (about GC identifiers)

Start:
54,172,657 bp from pter      End:
54,254,950 bp from pter
Size:
82,294 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: TINAG_HUMAN, Q9UJW2 (See protein sequence)
Recommended Name: Tubulointerstitial nephritis antigen  
Size: 476 amino acids; 54605 Da
Subcellular location: Secreted, extracellular space, extracellular matrix, basement membrane
Developmental stage: Initially observed in the Bowman capsule during early glomerular capillary loop formation in
the kidney. In more developmentally mature glomeruli, following transition from early to mid-capillary loop
stage, expression is higher in the proximal tubular basement membrane than in the distal basement membrane and
Bowman capsule
Miscellaneous: Antibodies against TINAG are found in sera of patients with tubulointerstitial nephritis, a rare
autoimmune disorder that causes acute and chronic renal injury
Secondary accessions: Q5T467 Q9UJW1 Q9ULZ4
Alternative splicing: 2 isoforms:  Q9UJW2-1   Q9UJW2-2   (Major isoform)

Explore the universe of human proteins at neXtProt for TINAG: NX_Q9UJW2

Explore proteomics data for TINAG at MOPED 

Post-translational modifications:

  • UniProtKB: It has been suggested that the active SMB domain may be permitted considerable disulfide bond heterogeneity or
    variability, thus 2 alternate disulfide patterns based on 3D structures are described with 1 disulfide bond
    conserved in both
  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q9UJW2

  • TINAG Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    TINAG Protein Expression
    REFSEQ proteins: NP_055279.3  
    ENSEMBL proteins: 
     ENSP00000359906   ENSP00000259782   ENSP00000359901  

    Human Recombinant Protein Products for TINAG: 
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    Novus Biologicals TINAG Lysates
    Browse Sino Biological Recombinant Proteins
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    Cloud-Clone Corp. Proteins for TINAG 

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005604basement membrane IDA1762287

    TINAG for ontologies           About GeneDecksing



    TINAG Antibody Products: 
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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    4 InterPro protein domains:
     IPR013128 Peptidase_C1A
     IPR025661 Pept_asp_AS
     IPR000668 Peptidase_C1A_C
     IPR001212 Somatomedin_B_dom

    Graphical View of Domain Structure for InterPro Entry Q9UJW2

    ProtoNet protein and cluster: Q9UJW2

    1 Blocks protein domain: IPB000668 Papain cysteine protease (C1) family signature

    UniProtKB/Swiss-Prot: TINAG_HUMAN, Q9UJW2
    Similarity: Belongs to the peptidase C1 family
    Similarity: Contains 1 SMB (somatomedin-B) domain


    TINAG for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: TINAG_HUMAN, Q9UJW2
    Function: Mediates adhesion of proximal tubule epithelial cells via integrins alpha3-beta1 and alphaV-beta3. This
    is a non catalytic peptidase C1 family protein

         Gene Ontology (GO): 5 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000166nucleotide binding TAS10652240
    GO:0004197cysteine-type endopeptidase activity TAS10652240
    GO:0005044scavenger receptor activity IEA--
    GO:0008234cysteine-type peptidase activity ----
    GO:0030247polysaccharide binding IEA--
         
    TINAG for ontologies           About GeneDecksing


    Phenotypes:
         1 MGI phenotypic allele for Tinag (no phenotypes)

    TINAG for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-out Tinagtm1Lex for TINAG

       inGenious Targeting Laboratory - Custom generated mouse model solutions for TINAG 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for TINAG

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for TINAG 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for TINAG 

    miRNA
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    Inhib. RNA
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TINAG


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for TINAG

    STRING Interaction Network Preview (showing 3 interactants - click image to see more details)

    3 Interacting proteins for TINAG (Q9UJW23 ENSP000002597824) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    TERF1P542743, ENSP000002766034I2D: score=1 STRING: ENSP00000276603
    CPB2ENSP000001813834STRING: ENSP00000181383
    TMEM45BENSP000002814414STRING: ENSP00000281441
    About this table

    Gene Ontology (GO): 3 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006508proteolysis IEA--
    GO:0006955immune response IEA--
    GO:0007155cell adhesion IDA8770961

    TINAG for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    TINAG for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for TINAG

    1 Novoseek inferred chemical compound relationship for TINAG gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    cysteine 36.4 2 10652240 (1), 10752525 (1)

    Search CenterWatch for drugs/clinical trials and news about TINAG

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for TINAG gene: 
    NM_014464.3  

    Unigene Cluster for TINAG:

    Tubulointerstitial nephritis antigen
    Hs.127011  [show with all ESTs]
    Unigene Representative Sequence: BC056235
    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000486436 ENST00000370869 ENST00000259782(uc003pci.3 uc003pcj.2 uc010jzt.2)
    ENST00000370864
    miRNA
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    Inhib. RNA
    Products:
         
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    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TINAG
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TINAG
    Sirion Biotech Customized lentivirus for stable overexpression of TINAG 
                         Customized lentivirus expression plasmids for stable overexpression of TINAG 
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TINAG
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TINAG

    Additional mRNA sequence: 

    AB022277.1 AF195116.1 AF195117.1 AK312918.1 BC056235.1 BC070278.1 

    5 DOTS entries:

    DT.40126748  DT.91744224  DT.91744226  DT.121321973  DT.75102042 

    24/65 AceView cDNA sequences (see all 65):

    AI241144 AW027949 BF591880 AI245487 AI479548 BX118861 BC056235 AA327564 
    AA934831 AI253049 BM857019 BF434442 AL698332 AB022277 AA974456 BI765216 
    AW139886 AW271405 BM794563 BM795244 BG427401 BF000045 AI627942 BV205467 

    GeneLoc Exon Structure

    5 Alternative Splicing Database (ASD) splice patterns (SP) for TINAG    About this scheme

    ExUns: 1 ^ 2 ^ 3a · 3b · 3c ^ 4 ^ 5a · 5b ^ 6a · 6b ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12a · 12b ^ 13 ^ 14a · 14b
    SP1:                                            -                                                           -               
    SP2:        -     -     -                       -                                                                           
    SP3:              -     -                                                                                                   
    SP4:                                                                                                                        
    SP5:                                                                                                                        


    ECgene alternative splicing isoforms for TINAG

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TINAG expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    TINAG Expression
    About this image


    See TINAG Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for TINAG

    SOURCE GeneReport for Unigene cluster: Hs.127011

    UniProtKB/Swiss-Prot: TINAG_HUMAN, Q9UJW2
    Tissue specificity: Expressed in the kidney cortex, small intestine and cornea

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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for TINAG gene from 5/11 species (see all 11)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Tinag1 , 5 tubulointerstitial nephritis antigen1, 5 86.81(n)1
    85.68(a)1
      9 (42.67 cM)5
    269441  NM_012033.31  NP_036163.31 
     769516985 
    chicken
    (Gallus gallus)
    Aves TINAG1 tubulointerstitial nephritis antigen 62.82(n)
    55.99(a)
      421888  XM_419905.3  XP_419905.3 
    lizard
    (Anolis carolinensis)
    Reptilia TINAG6
    tubulointerstitial nephritis antigen
    54(a)
    1 ↔ 1
    GL343342.1(244308-299553)
    fruit fly
    (Drosophila melanogaster)
    Insecta CG30743 cathepsin B 39(a)   58C7   --
    worm
    (Caenorhabditis elegans)
    Secernentea F26E4.33 cysteine protease 41(a)   I(9770626-9775999)   --


    ENSEMBL Gene Tree for TINAG (if available)
    TreeFam Gene Tree for TINAG (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for TINAG gene
    CTSF2  CTSO2  CTSW2  CTSV2  CTSK2  CTSB2  CTSS2  CTSH2  
    CTSC2  TINAGL12  CTSZ2  CTSL2  
    1 SIMAP similar gene for TINAG using alignment to 6 protein entries:     TINAG_HUMAN (see all proteins):
    TINAGL1

    TINAG for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/1938 SNPs in TINAG are shown (see all 1938)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 6 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1932268031,2
    --54171284(+) ATTTCA/GAATGA 1 -- us2k10--------
    rs1839492751,2
    --54171315(+) TGAATC/TCAAAA 1 -- us2k10--------
    rs1459473621,2
    --54171344(+) AGCATA/TGTGAA 1 -- us2k10--------
    rs1877183391,2
    --54171395(+) CAAGGA/GAGGAA 1 -- us2k10--------
    rs1397969731,2
    --54171417(+) TAGTGA/GGTATG 1 -- us2k10--------
    rs1148371891,2
    F--54171457(+) CATGTG/TTGATG 1 -- us2k11Minor allele frequency- T:0.07WA 118
    rs1422275671,2
    --54171486(+) ATTATC/GGCATT 1 -- us2k10--------
    rs1923456931,2
    --54171503(+) TCCCAC/TCCATC 1 -- us2k10--------
    rs1841747701,2
    --54171608(+) GCAGAA/TCTAGG 1 -- us2k10--------
    rs37568081,2
    C,F,A,H--54171624(-) CTAATG/AGAATT 1 -- us2k121Minor allele frequency- A:0.46NS EA NA CSA WA 2348

    HapMap Linkage Disequilibrium report for TINAG (54172657 - 54254950 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for TINAG:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv819178CNV Gain19587683
    nsv885888CNV Gain21882294


    Human Gene Mutation Database (HGMD): TINAG
    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing TINAG
    DNA2.0 Custom Variant and Variant Library Synthesis for TINAG

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 606749    OMIM disorders: --

    2 diseases for TINAG:    About MalaCards
    nephritis    nephronophthisis

    2 diseases from the University of Copenhagen DISEASES database for TINAG:
    Nephronophthisis     Nephritis

    TINAG for disorders           About GeneDecksing

    3 Novoseek inferred disease relationships for TINAG gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    tubulointerstitial nephritis 95.1 36 7608193 (2), 9643646 (2), 8770961 (2), 19297554 (2) (see all 16)
    nephritis 57.6 1 1466368 (1)
    nephropathy membranous 55.6 1 1466368 (1)

    Genetic Association Database (GAD): TINAG
    Human Genome Epidemiology (HuGE) Navigator: TINAG (1 document)

    Export disorders for TINAG gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for TINAG gene, integrated from 9 sources (see all 27):
    (articles sorted by number of sources associating them with TINAG)
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    1. Molecular cloning, expression, and chromosomal localization of a human tubulointerstitial nephritis antigen. (PubMed id 10652240)1, 2, 3, 9 Ikeda M.... Yoshioka K. (2000)
    2. Identification of two alternatively spliced forms of human tubulointerstitial nephritis antigen (TIN-Ag). (PubMed id 10752525)1, 2, 9 Zhou B....Charonis A.S. (2000)
    3. Tubulointerstitial nephritis antigen (TIN-ag) is expressed in distinct segments of the developing human nephron. (PubMed id 9643646)1, 2, 9 Nelson T.R.... Charonis A.S. (1998)
    4. Receptors in proximal tubular epithelial cells for tubulointerstitial nephritis antigen. (PubMed id 8770961)1, 2, 9 Chen Y.... Charonis A.S. (1996)
    5. Role of antibodies to tubulointerstitial nephritis antigen in human anti-tubular basement membrane nephritis associated with membranous nephropathy. (PubMed id 1466368)1, 2, 9 Katz A....Butkowski R.J. (1992)
    6. Distribution of tubulointerstitial nephritis antigen and evidence for multiple forms. (PubMed id 1762287)1, 2, 9 Butkowski R.J.... Fish A.J. (1991)
    7. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (2010)
    8. Radiation pharmacogenomics: a genome-wide association approach to identify radiation response biomarkers using human lymphoblastoid cell lines. (PubMed id 20923822)1, 4 Niu N....Wang L. (2010)
    9. Identification of a target antigen in human anti-tubular basement membrane nephritis. (PubMed id 3553704)1, 2 Fliger F.D....Butkowski R.J. (1987)
    10. A tubulointerstitial nephritis antigen gene defect ca uses childhood-onset chronic renal failure. (PubMed id 20157734)1, 9 Takemura Y....Takemura T. (2010)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 27283 HGNC: 14599 AceView: TINAG Ensembl:ENSG00000137251 euGenes: HUgn27283
    ECgene: TINAG H-InvDB: TINAG

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for TINAG Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for TINAG gene:
    Search GeneIP for patents involving TINAG

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