Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 
or upload a file of gene symbols


Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

TIMMDC1 Gene

protein-coding   GIFtS: 44
GCID: GC03P119218

Translocase Of Inner Mitochondrial Membrane Domain Containing...

(Previous name: chromosome 3 open reading frame 1)
(Previous symbol: C3orf1)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Translocase Of Inner Mitochondrial Membrane Domain Containing 11 2     Translocase Of Inner Mitochondrial Membrane Domain-Containing Protein 12
C3orf11 2 3     Transmembrane Protein C3orf12
Chromosome 3 Open Reading Frame 11     Protein M5-143
M5-14 Protein2     

External Ids:    HGNC: 13211   Entrez Gene: 513002   Ensembl: ENSG000001138457   UniProtKB: Q9NPL83   

Export aliases for TIMMDC1 gene to outside databases


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for TIMMDC1 Gene: 
TIMMDC1 (translocase of inner mitochondrial membrane domain containing 1) is a protein-coding gene. Diseases associated with TIMMDC1 include primary biliary cirrhosis, and intrahepatic cholangiocarcinoma.

Gene Wiki entry for TIMMDC1 (C3orf1) Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000003.11  NT_005612.16  NC_018914.2  
Regulatory elements:
   Search SABiosciences Regulatory transcription factor binding sites for TIMMDC1
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidTIMMDC1 promoter sequence
   Search SABiosciences Chromatin IP Primers for TIMMDC1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TIMMDC1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 3q13.33   Ensembl cytogenetic band:  3q13.33   HGNC cytogenetic band: 3q13.33

TIMMDC1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TIMMDC1 gene location

GeneLoc information about chromosome 3         GeneLoc Exon Structure

GeneLoc location for GC03P119218:  view genomic region     (about GC identifiers)

Start:
119,217,368 bp from pter      End:
119,243,937 bp from pter
Size:
26,570 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: TIDC1_HUMAN, Q9NPL8 (See protein sequence)
Recommended Name: Translocase of inner mitochondrial membrane domain-containing protein 1  
Size: 285 amino acids; 32178 Da
Subcellular location: Membrane; Multi-pass membrane protein (Potential)
Secondary accessions: D3DN81 Q6IAJ7 Q6UWU6 Q9NPR3 Q9NPS5 Q9P0Y6

Explore the universe of human proteins at neXtProt for TIMMDC1: NX_Q9NPL8

Explore proteomics data for TIMMDC1 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q9NPL8

  • TIMMDC1 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    TIMMDC1 Protein Expression
    REFSEQ proteins: NP_057673.2  
    ENSEMBL proteins: 
     ENSP00000418803   ENSP00000419510   ENSP00000264244   ENSP00000417083   ENSP00000418846  
     ENSP00000420122   ENSP00000417205   ENSP00000420812  

    Human Recombinant Protein Products for TIMMDC1: 
    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    OriGene Protein Over-expression Lysate for TIMMDC1
    OriGene Custom MassSpec 
    OriGene Custom Protein Services for TIMMDC1
    GenScript Custom Purified and Recombinant Proteins Services for TIMMDC1
    Novus Biologicals TIMMDC1 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Browse Proteins at Cloud-Clone Corp. 

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005739mitochondrion IDA--
    GO:0016021integral to membrane IEA--

    TIMMDC1 for ontologies           About GeneDecksing



    TIMMDC1 Antibody Products: 
    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for TIMMDC1
    GenScript Custom Superior Antibodies Services for TIMMDC1
    Novus Biologicals TIMMDC1 Antibody
    Abcam antibodies for TIMMDC1
    Browse Antibodies at Cloud-Clone Corp. 
    ThermoFisher Antibodies for TIMMDC1
    Search LSBio for Antibodies for TIMMDC1 

    Assay Products for TIMMDC1: 
    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for TIMMDC1
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for TIMMDC1
    Browse Enzo Life Sciences for kits & assays
    Browse ELISAs at Cloud-Clone Corp. 
    Browse CLIAs at Cloud-Clone Corp.


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    1 InterPro protein domain:
     IPR003397 Tim17/Tim22/Tim23/PMP24

    Graphical View of Domain Structure for InterPro Entry Q9NPL8

    ProtoNet protein and cluster: Q9NPL8

    1 Blocks protein domain: IPB003397 Mitochondrial import inner membrane translocase

    UniProtKB/Swiss-Prot: TIDC1_HUMAN, Q9NPL8
    Similarity: Belongs to the Tim17/Tim22/Tim23 family


    TIMMDC1 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Phenotypes:
         3 MGI mutant phenotypes (inferred from 1 allele(MGI details for Timmdc1):
     hematopoietic system  immune system  mortality/aging 

    TIMMDC1 for phenotypes           About GeneDecksing

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for TIMMDC1 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for TIMMDC1

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for TIMMDC1 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for TIMMDC1 

    miRNA
    Products:
        
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat TIMMDC1
    1 QIAGEN miScript miRNA Assays for microRNA that regulate TIMMDC1:
    hsa-miR-3924
    SwitchGear 3'UTR luciferase reporter plasmidTIMMDC1 3' UTR sequence
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for TIMMDC1
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TIMMDC1

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for TIMMDC1
    Sirion Biotech Customized adenovirus for overexpression of TIMMDC1

    Clone
    Products:
         
    Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene clones in human, mouse for TIMMDC1 (see all 8)
    OriGene ORF clones in mouse, rat for TIMMDC1
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript Custom all cDNA clones Services for TIMMDC1
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TIMMDC1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TIMMDC1
    Sirion Biotech Customized lentivirus for stable overexpression of TIMMDC1 
                         Customized lentivirus expression plasmids for stable overexpression of TIMMDC1 

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for TIMMDC1
    Search LifeMap BioReagents cell lines for TIMMDC1
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TIMMDC1


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for TIMMDC1

    STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

    1 Interacting protein for TIMMDC1 (Q9NPL83 ENSP000004188034) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    HGSO149643, ENSP000003312014I2D: score=1 STRING: ENSP00000331201
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for TIMMDC1 (TIDC1)

    Search CenterWatch for drugs/clinical trials and news about TIMMDC1 / TIDC1

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for TIMMDC1 gene: 
    NM_016589.3  

    Unigene Cluster for TIMMDC1:

    Translocase of inner mitochondrial membrane domain containing 1
    Hs.477287  [show with all ESTs]
    Unigene Representative Sequence: NM_016589
    9 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000494664(uc003ecn.3 uc003eco.3 uc003ecp.3) ENST00000493694
    ENST00000264244 ENST00000486418 ENST00000492164 ENST00000466984 ENST00000463927
    ENST00000498399 ENST00000469324
    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat TIMMDC1
    1 QIAGEN miScript miRNA Assays for microRNA that regulate TIMMDC1:
    hsa-miR-3924
    SwitchGear 3'UTR luciferase reporter plasmidTIMMDC1 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for TIMMDC1
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TIMMDC1
    Clone
    Products:
         
    OriGene clones in human, mouse for TIMMDC1 (see all 8)
    OriGene ORF clones in mouse, rat for TIMMDC1
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript Custom all cDNA clones Services for TIMMDC1
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TIMMDC1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TIMMDC1
    Sirion Biotech Customized lentivirus for stable overexpression of TIMMDC1 
                         Customized lentivirus expression plasmids for stable overexpression of TIMMDC1 
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for TIMMDC1
    OriGene qSTAR qPCR primer pairs in human, mouse for TIMMDC1
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat TIMMDC1
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TIMMDC1
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TIMMDC1

    Additional mRNA sequence: 

    AF139077.1 AF210057.1 AK026250.1 AK225954.1 AL136622.1 AL390077.1 AL390090.1 AL390094.1 
    AY358633.1 BC012341.1 CR457158.1 CR533524.1 

    13 DOTS entries:

    DT.455212  DT.101984379  DT.100660806  DT.100721374  DT.102826710  DT.95186853  DT.100030187  DT.100030189 
    DT.95186851  DT.95186801  DT.95308221  DT.100690426  DT.40116899 

    24/436 AceView cDNA sequences (see all 436):

    CA416598 AW301594 AW337452 BU157810 BQ016025 CR591661 AI745072 BU628187 
    BU737838 AW172845 CA423380 CA416536 BQ575479 AI362614 BF062474 BE221926 
    BM976665 AA845315 AI537728 BQ128299 AA496948 BM848298 AW190546 AI521959 

    GeneLoc Exon Structure

    5/11 Alternative Splicing Database (ASD) splice patterns (SP) for TIMMDC1 (see all 11)    About this scheme

    ExUns: 1a · 1b · 1c · 1d · 1e · 1f · 1g · 1h ^ 2a · 2b ^ 3 ^ 4 ^ 5a · 5b ^ 6 ^ 7a · 7b · 7c
    SP1:                                            -     -                                                         
    SP2:                                                  -                                                         
    SP3:                                            -     -                       -     -                           
    SP4:                                            -     -     -                                                   
    SP5:                                            -     -     -     -                                             


    ECgene alternative splicing isoforms for TIMMDC1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TIMMDC1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AATATATCCA
    TIMMDC1 Expression
    About this image


    See TIMMDC1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for TIMMDC1

    SOURCE GeneReport for Unigene cluster: Hs.477287

    UniProtKB/Swiss-Prot: TIDC1_HUMAN, Q9NPL8
    Tissue specificity: Generalized expression enhanced in heart and skeletal muscle

        SABiosciences Custom PCR Arrays for TIMMDC1
    Primer
    Products:
    OriGene qPCR primer pairs and template standards for TIMMDC1
    OriGene qSTAR qPCR primer pairs in human, mouse for TIMMDC1
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat TIMMDC1
    QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TIMMDC1
    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TIMMDC1
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TIMMDC1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for TIMMDC1 gene from 6/12 species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Timmdc11 , 5 RIKEN cDNA 4930455C21 gene5
    translocase of inner mitochondrial membrane domain more1
    78.17(n)1
    71.48(a)1
      16 (26.86 cM)5
    769161  NM_024273.21  NP_077235.21 
     384983475 
    chicken
    (Gallus gallus)
    Aves TIMMDC11 translocase of inner mitochondrial membrane domain more 58.72(n)
    51.87(a)
      418453  XM_429582.3  XP_429582.3 
    lizard
    (Anolis carolinensis)
    Reptilia TIMMDC16
    Uncharacterized protein
    51(a)
    1 ↔ 1
    3(162394812-162406054)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.20452 Xenopus laevis transcribed sequence with weak similarity more 69.18(n)    48025782 
    zebrafish
    (Danio rerio)
    Actinopterygii Dr.183692 Transcribed sequence with weak similarity to protein more 69.41(n)    CK353638.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta 140up1 upstream of RpII140 45.61(n)
    31.36(a)
      41720  NM_057603.5  NP_476951.1 


    ENSEMBL Gene Tree for TIMMDC1 (if available)
    TreeFam Gene Tree for TIMMDC1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/601 SNPs in TIMMDC1 are shown (see all 601)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 3 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs716197481,2
    C--116617370(+) GTGTG-/TGTG  
     
    /TGTGTG
    AGATA
    1 -- int11NA 2
    rs1823299271,2
    --119215698(+) ACAGTA/GCGAGC 1 -- us2k10--------
    rs1147137201,2
    C,F--119215773(+) CTTCCG/ATTACC 1 -- us2k11Minor allele frequency- A:0.04WA 118
    rs1152565941,2
    C--119215778(+) GTTACA/CCAAAT 1 -- us2k10--------
    rs1915085511,2
    --119216012(+) CAGCCA/GTTTTC 1 -- us2k10--------
    rs1449489401,2
    C--119216057(+) CCCACC/TTCTAC 1 -- us2k10--------
    rs1831154151,2
    --119216145(+) ACTGCA/GGTTCT 1 -- us2k10--------
    rs1479444051,2
    --119216244(+) TGTTGC/TAAGTG 1 -- us2k10--------
    rs1881903941,2
    --119216511(+) TACACA/GAATAT 1 -- us2k10--------
    rs20495001,2
    C,F,O,A,H--119216554(-) AAGTAC/TAGTTT 1 -- us2k128Minor allele frequency- N:0.00MN NS EA NA WA CSA 4409

    HapMap Linkage Disequilibrium report for TIMMDC1 (119217368 - 119243937 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for TIMMDC1:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv829695CNV Loss17160897

    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing TIMMDC1
    DNA2.0 Custom Variant and Variant Library Synthesis for TIMMDC1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    7 diseases for TIMMDC1:    About MalaCards
    primary biliary cirrhosis    intrahepatic cholangiocarcinoma    cholangiocarcinoma    chronic lymphocytic leukemia
    multiple sclerosis    arthritis    leukemia


    TIMMDC1 for disorders           About GeneDecksing


    Export disorders for TIMMDC1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for TIMMDC1 gene, integrated from 9 sources (see all 24):
    (articles sorted by number of sources associating them with TIMMDC1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Identification and expression analysis of C3orf1, a novel human gene homologous to the Drosophila RP140-upstream gene. (PubMed id 11092749)1, 2, 3 Escarceller M.... Estivill X. (2000)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    3. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)1, 2 Clark H.F.... Gray A.M. (2003)
    4. Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PubMed id 11230166)1, 2 Wiemann S.... Poustka A. (2001)
    5. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
    6. Genome-wide association analysis of juvenile idiopathi c arthritis identifies a new susceptibility locus at chromosomal region 3q13. (PubMed id 22354554)1 Thompson S.D....Glass D.N. (2012)
    7. Genome-wide association study identifies TNFSF15 and P OU2AF1 as susceptibility loci for primary biliary cirrhosis in the Japanese popu lation. (PubMed id 23000144)1 Nakamura M....Ishibashi H. (2012)
    8. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
    9. Genome-wide association study identifies 12 new susce ptibility loci for primary biliary cirrhosis. (PubMed id 21399635)1 Mells G.F....Anderson C.A. (2011)
    10. Genetic risk and a primary role for cell-mediated immu ne mechanisms in multiple sclerosis. (PubMed id 21833088)1  ....Compston A. (2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 51300 HGNC: 1321 AceView: C3orf1 Ensembl:ENSG00000113845 euGenes: HUgn51300
    ECgene: TIMMDC1 H-InvDB: TIMMDC1

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for TIMMDC1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for TIMMDC1 gene:
    Search GeneIP for patents involving TIMMDC1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

     
     EMD Millipore Custom Antibody & Bulk Services
     EMD Millipore Preclinical / Clinical Development Services
     EMD Millipore Immunoassay Services
     EMD Millipore Target Screening & Profiling Services

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Kinase Activity Assays/Reagents  
     Browse ELISpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Multiplex/Array Assay Kits/Reagents  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Protease Activity Assays and Reagents   Browse Recombinant/Natural Proteins  
     Browse Stem Cell Products   Browse Tocris Biochemicals & Compounds  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for TIMMDC1  
     OriGene qPCR primer pairs and template standards for TIMMDC1   OriGene Protein Over-expression Lysate for TIMMDC1  
     OriGene Custom Mass Spec   OriGene clones in human, mouse for TIMMDC1  
     OriGene qSTAR qPCR primer pairs in human, mouse for TIMMDC1   Browse OriGene full length recombinant human proteins expressed in human HEK293 cells  
     OriGene ORF clones in mouse, rat for TIMMDC1   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for TIMMDC1   OriGene Custom Protein Services for TIMMDC1  

     
     
     QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat TIMMDC1
     QIAGEN SeqTarget long-range PCR primers for resequencing TIMMDC1
     QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TIMMDC1
     QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TIMMDC1
     QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TIMMDC1
     QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TIMMDC1
     GenScript Custom Purified and Recombinant Proteins Services for TIMMDC1 GenScript Custom cDNA clones with any tag delivered in your preferred vector Services for TIMMDC1
     GenScript Custom Assay Services for TIMMDC1 GenScript Custom Superior Antibodies Services for TIMMDC1
     GenScript Custom overexpressing Cell Line Services for TIMMDC1 CloneReady with Over 120,000 Genes
     Gene Synthesis: Any Gene in Any Vector Vector-based siRNA and miRNA, Ready for Transfection
     Gene Mutant Library, Variants up to 10^11 Plasmid Preparation
     Custom Peptide Services
     Search for Antibodies & Assays

     Search Regulatory tfbs for TIMMDC1
     Search Chromatin IP Primers for TIMMDC1
     RT2 qPCR Primer Assay in human, mouse, rat TIMMDC1
     Search GNC Networks for TIMMDC1
     SABiosciences Custom PCR Arrays for TIMMDC1
     Search Tocris compounds for TIMMDC1 (TIDC1)
     Browse Sino Biological Proteins and Antibodies
     Browse Sino Biological Cell Lysates
     Browse Sino Biological cDNA Clones
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies
     Novus Tissue Slides
     TIMMDC1 antibodies
     TIMMDC1 lysates
     Antibodies for TIMMDC1
     See all of Abcam's Antibodies, Kits and Proteins for TIMMDC1
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins




     Browse Proteins at Cloud-Clone Corp.
     Browse Antibodies at Cloud-Clone Corp.
     Browse ELISAs at Cloud-Clone Corp.
     Browse CLIAs at Cloud-Clone Corp.
     Search LifeMap BioReagents cell lines for TIMMDC1
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TIMMDC1
     SwitchGear 3'UTR luciferase reporter plasmids for TIMMDC1
     SwitchGear Promoter luciferase reporter plasmids for TIMMDC1
     ThermoFisher Antibodies for TIMMDC1
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TIMMDC1
     inGenious Targeting Laboratory - Custom generated mouse model solutions for TIMMDC1
     inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for TIMMDC1
    Customized:
     lentivirus for stable overexpression of TIMMDC1
     lentivirus expression plasmids for stable overexpression of TIMMDC1
     adenovirus for overexpression of TIMMDC1
     Search LSBio for Antibodies for TIMMDC1
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
           
    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

    View Random Gene

    Category
    (GIFtS: 73)
    transforming growth factor, beta 1
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      TIMMDC1 gene at Home site.
    hostname: 356977-web1.xennexinc.com index build: 106 solr: 1.4