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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

TIMM8B Gene

protein-coding   GIFtS: 53
GCID: GC11M111989

translocase of inner mitochondrial membrane 8 homolog B...

(Previous name: translocase of inner mitochondrial membrane 8 (yeast) homolog...)
 Explore 4 diseases affiliated with
TIMM8B via our new
 Human Malady Compendium 
Biological research products
for TIMM8B
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

This gene clusters with an RNA gene
Subcategory (RNA class): lncRNA

Quality score for the ORGUL clustered with this gene is 3

Aliases
Translocase Of Inner Mitochondrial Membrane 8 Homolog B (Yeast)1 2     MGC1028661
DDP21 2 3     MGC1173731
TIM8B1 2 3     Translocase Of Inner Mitochondrial Membrane 8 (Yeast) Homolog B1
Deafness Dystonia Protein 22 3     Mitochondrial Import Inner Membrane Translocase Subunit Tim8 B2
DDP-Like Protein2 3     DDPL3
FLJ217441     

External Ids:    HGNC: 118181   Entrez Gene: 265212   Ensembl: ENSG000001507797   OMIM: 6066595   UniProtKB: Q9Y5J93   
ORGUL members:         
NONCODE:n408220    

Export aliases for TIMM8B gene to outside databases

Previous GC identifers: GC11M114308 GC11M113467 GC11M111493 GC11M111461 GC11M107879


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for TIMM8B:
This gene encodes a member of a well-conserved family of proteins with similarity to yeast Tim mitochondrial import
proteins. This gene is encoded by a nuclear gene and is transported into the intermembrane space of the mitochondrion.
When formed into complexes, these proteins guide membrane-spanning proteins across the mitochondrial intermembrane
space before they are added into the mitochondrial inner membrane. This gene is adjacent to succinate dehydrogenase,
subunit D (SDHD), in which mutations have been found in affected members of families with hereditary
paraganglioma.(provided by RefSeq, Aug 2009)

UniProtKB/Swiss-Prot: TIM8B_HUMAN, Q9Y5J9
Function: Probable mitochondrial intermembrane chaperone that participates in the import and insertion of some
multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel
precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a
chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the
mitochondrial intermembrane space (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000011.9  NC_018922.1  NT_033899.8  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the TIMM8B gene promoter:
         AML1a   FOXO3   FOXD3   POU3F2 (N-Oct-5a)   POU3F2 (N-Oct-5b)   POU3F2   FOXO3b   RORalpha1   AREB6   Nkx6-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidTIMM8B promoter sequence
   Search SABiosciences Chromatin IP Primers for TIMM8B

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TIMM8B


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 11q23.1-q23.2   Ensembl cytogenetic band:  11q23.1   HGNC cytogenetic band: 11q23.1-q23.2

TIMM8B Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TIMM8B gene location

GeneLoc information about chromosome 11         GeneLoc Exon Structure

GeneLoc location for GC11M111989:  view genomic region     (about GC identifiers)

Start:
111,955,524 bp from pter      End:
111,957,522 bp from pter
Size:
1,999 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: TIM8B_HUMAN, Q9Y5J9 (See protein sequence)
Recommended Name: Mitochondrial import inner membrane translocase subunit Tim8 B  
Size: 83 amino acids; 9344 Da
Subunit: Heterohexamer; possibly composed of 3 copies of TIMM8B and 3 copies of TIMM13, named soluble 70 kDa complex.
Associates with the TIM22 complex, whose core is composed of TIMM22 (By similarity)
Subcellular location: Mitochondrion inner membrane; Peripheral membrane protein; Intermembrane side (By similarity)
Secondary accessions: B0YJA5 Q3KQS9 Q9UN04

Explore the universe of human proteins at neXtProt for TIMM8B: NX_Q9Y5J9

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q9Y5J9

  • TIMM8B Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_036591.2  
    ENSEMBL proteins: 
     ENSP00000422122   ENSP00000421964   ENSP00000438455  
    Reactome Protein details: Q9Y5J9
    Human Recombinant Protein Products: 
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    Novus Biologicals TIMM8B Proteins
    Novus Biologicals TIMM8B Lysate
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    Browse ProSpec Recombinant Proteins
    Uscn Proteins for TIMM8B

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005739mitochondrion ----
    GO:0005743mitochondrial inner membrane IEA--
    GO:0042719mitochondrial intermembrane space protein transporter complex TAS10552927


    TIMM8B for ontologies           About GeneDecksing



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    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    TIMM8B for domains           About GeneDecksing

    1 InterPro domain/family:
     IPR004217 zf-Tim10_DDP

    Graphical View of Domain Structure for InterPro Entry Q9Y5J9

    ProtoNet protein and cluster: Q9Y5J9

    1 Blocks protein family: IPB004217 Zn-finger

    UniProtKB/Swiss-Prot: TIM8B_HUMAN, Q9Y5J9
    Domain: The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial
    intermembrane space. However, during the transit of TIMM8B from cytoplasm into mitochondrion, the Cys residues
    probably coordinate zinc, thereby preventing folding and allowing its transfer across mitochondrial outer membrane (By
    similarity)
    Similarity: Belongs to the small Tim family


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Function Summary:

         UniProtKB/Swiss-Prot: TIM8B_HUMAN, Q9Y5J9
    Function: Probable mitochondrial intermembrane chaperone that participates in the import and insertion of some
    multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel
    precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a
    chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the
    mitochondrial intermembrane space (By similarity)

         Genatlas biochemistry entry for TIMM8B:
    translocase of inner mitochondrial membrane 8 (yeast) homolog B,ubiquitously expressed,highly in cardiac and skeletal
    muscle,S cerevisiae Tim8p ortholog,component of the Tm complex

    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat TIMM8B
    8/9 QIAGEN miScript miRNA Assays for microRNAs that regulate TIMM8B (see all 9):
    hsa-miR-320a hsa-miR-3942-5p hsa-miR-513a-3p hsa-miR-320d hsa-miR-4255 hsa-miR-29c hsa-miR-29a hsa-miR-320b
    SwitchGear 3'UTR luciferase reporter plasmidTIMM8B 3' UTR sequence
    Inhib. RNA
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    Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008270zinc ion binding TAS10552927
    GO:0046872metal ion binding ----


    TIMM8B for ontologies           About GeneDecksing


    1 GenomeRNAi human phenotype for TIMM8B:
     Increased gamma-H2AX phosphory 


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Mitochondrial Protein Import
    Mitochondrial Protein Import1.00
    2Asparagine N-linked glycosylation
    Metabolism of proteins0.15

    Pathway sources
    See GeneCards unified pathways
    Show all pathways


    2        Reactome Pathways for TIMM8B
        Mitochondrial Protein Import
    Metabolism of proteins



    TIMM8B for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for TIMM8B

    1 Interacting protein for TIMM8B (Q9Y5J93) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    TIMM13Q9Y5L43I2D: score=2 
    About this table

    Gene Ontology (GO): 5 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006626protein targeting to mitochondrion TAS--
    GO:0007605sensory perception of sound TAS10552927
    GO:0044267cellular protein metabolic process TAS--
    GO:0045039protein import into mitochondrial inner membrane IEA--
    GO:0072321chaperone-mediated protein transport TAS16387659


    TIMM8B for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for TIMM8B
    Search CenterWatch for drugs/clinical trials and news about TIMM8B / TIM8B 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for TIMM8B gene: 
    NM_012459.2  

    Unigene Cluster for TIMM8B:

    Translocase of inner mitochondrial membrane 8 homolog B (yeast)
    Hs.279915  [show with all ESTs]
    Unigene Representative Sequence: NR_028383
    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000504148 ENST00000509359(uc001pmy.3 uc001pmx.3) ENST00000507614
    ENST00000541231

    miRNA
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    8/9 QIAGEN miScript miRNA Assays for microRNAs that regulate TIMM8B (see all 9):
    hsa-miR-320a hsa-miR-3942-5p hsa-miR-513a-3p hsa-miR-320d hsa-miR-4255 hsa-miR-29c hsa-miR-29a hsa-miR-320b
    SwitchGear 3'UTR luciferase reporter plasmidTIMM8B 3' UTR sequence
    Inhib. RNA
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TIMM8B
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TIMM8B

    Additional cDNA sequence: 

    AF150087.1 AF152350.1 AF165967.1 AK025397.1 AK312169.1 BC000711.2 BC105986.1 BC106067.1 
    NR_028383.1 

    19 DOTS entries:

    DT.101983723  DT.86854195  DT.95138569  DT.92443760  DT.97859482  DT.97859481  DT.95178970  DT.120733807 
    DT.91973611  DT.101982480  DT.100651701  DT.95178994  DT.453563  DT.95178964  DT.100694767  DT.120733864 
    DT.101982479  DT.120733741  DT.120733838 

    24/255 AceView cDNA sequences (see all 255):

    AA864797 AW302480 AW192353 AV712137 CA952824 AK025397 CA307054 AA442121 
    CA952567 AL536999 N57799 AA441909 Z45606 CA952624 AI580946 BG398497 
    BG941989 F37171 AW009069 AW204166 AI660467 AI581802 AA678102 AA594792 

    GeneLoc Exon Structure

    3 Alternative Splicing Database (ASD) splice patterns (SP) for TIMM8B    About this scheme

    ExUns: 1a · 1b ^ 2a · 2b ^ 3a · 3b · 3c
    SP1:                    -                     
    SP2:                                          
    SP3:              -     -                     


    ECgene alternative splicing isoforms for TIMM8B

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TIMM8B expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: GAGTTATGTT

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)

    About this image
    See TIMM8B Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for TIMM8B

    SOURCE GeneReport for Unigene cluster: Hs.279915

    UniProtKB/Swiss-Prot: TIM8B_HUMAN, Q9Y5J9
    Tissue specificity: Ubiquitous, with highest expression in heart, kidney, liver and skeletal muscle

        SABiosciences Expression via Pathway-Focused PCR Array including TIMM8B: 
              Mitochondria in human mouse rat

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    In Situ
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TIMM8B

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for TIMM8B gene from 5/19 species (see all 19)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    African clawed frog
    (Xenopus laevis)
    Amphibia BJ612182.12   -- 76.88(n)    BJ612182.1 
    zebrafish
    (Danio rerio)
    Actinopterygii Dr.150182 Transcribed sequence with moderate similarity to protein more 73.33(n)    CF543883.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta Tim81 CG1728-PA 60.44(n)
    58.67(a)
      32081  NM_132485.3  NP_572713.1 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons TIM86
    mitochondrial import inner membrane translocase su...
    32(a)
    1 → many
    5(20675634-20676612)
    rice
    (Oryza sativa)
    Liliopsida --
    --
    mitochondrial import inner membrane translocase su...
    mitochondrial import inner membrane translocase su...
    29(a)
    27(a)
    many ↔ many
    many ↔ many
    8(26747222-26748299)
    11(1441725-1443670)


    ENSEMBL Gene Tree for TIMM8B (if available)
    TreeFam Gene Tree for TIMM8B (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for TIMM8B gene
    TIMM8A2  
    2 SIMAP similar genes for TIMM8B using alignment to 3 protein entries:     TIM8B_HUMAN (see all proteins):
    TIMM8A    TIMM13

    TIMM8B for paralogs           About GeneDecksing


    2 Pseudogenes.org Pseudogenes for TIMM8B
    PGOHUM00000248350 PGOHUM00000250087


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    9 NCBI SNPs in TIMM8B are shown     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 11 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs71230751,2
    C,F,H,--107879277(+) TAAAGG/TGAGAA 2 -- ds5001 int113Minor allele frequency- T:0.11NS EA NA WA CSA 1298
    rs1889712131,2
    --111955028(+) GTTGGC/TATTTT 5 -- ut31 int1 ds50010--------
    rs1816654071,2
    --111955064(+) CTTTAC/TGGGAC 5 -- int1 ut31 ds50010--------
    rs5441841,2
    C,F,A,--111955483(+) CCCAAA/GTTAGC 5 -- ds5001 ut31 int114Minor allele frequency- N:0.00MN EA NA NS WA 806
    rs37409711,2
    C,--111955497(-) GAAAGA/CACAAG 5 -- ut31 int1 ds50010--------
    rs108121,2
    C,F,H,--111955502(-) CTTGCG/AAAAGA 5 -- ut31 int1 ds500127Minor allele frequency- A:0.33MN NA NS EA 3076
    rs713016981,2
    C--111955524(-) AAAAAAAA/-AAAAA 5 -- ut31 nc-transcript-variant1Minor allele frequency- -:0.50NA 2
    rs1912954211,2
    --111955568(+) CATGTA/GTAAGC 5 -- ut31 nc-transcript-variant0--------
    rs49370111,2
    ----107879579(+) CCATGG/TTTTCC 2 -- ut31 nc-transcript-variant0--------

    HapMap Linkage Disequilibrium report for TIMM8B (111955524 - 111957522 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for TIMM8B: --

    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing TIMM8B
    DNA2.0 Custom Variant and Variant Library Synthesis for TIMM8B

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    TIMM8B for disorders           About GeneDecksing

    OMIM gene information: 606659    OMIM disorders: --

    4 diseases for TIMM8B:    About MalaCards
    mohr-tranebjaerg syndrome    paraganglioma    familial deafness    twinning

    1 disease from the University of Copenhagen DISEASES database for TIMM8B:
    Paraganglioma
    Human Genome Epidemiology (HuGE) Navigator: TIMM8B (4 documents)

    Export disorders for TIMM8B gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for TIMM8B gene, integrated from 9 sources (see all 18):
    (articles sorted by number of sources associating them with TIMM8B)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The human family of deafness/dystonia peptide (DDP) related mitochondrial import proteins. (PubMed id 10552927)1, 2, 3 Jin H.... Vetrie D.L.P. (1999)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    3. The mitochondrial TIM22 preprotein translocase is highly conserved throughout the eukaryotic kingdom. (PubMed id 10611480)1, 2 Bauer M.F.... Hofmann S. (1999)
    4. Global landscape of HIV-human protein complexes. (PubMed id 22190034)1 Jager S....Krogan N.J. (2012)
    5. Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (2012)
    6. Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)
    7. A data set of human endogenous protein ubiquitination sites. (PubMed id 20972266)1 Shi Y....Qin J. (2011)
    8. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
    9. Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)
    10. Global analysis of lysine ubiquitination by ubiquitin remnant immunoaffinity profiling. (PubMed id 20639865)1 Xu G....Jaffrey S.R. (2010)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 26521 HGNC: 11818 AceView: TIMM8B Ensembl:ENSG00000150779 euGenes: HUgn26521
    ECgene: TIMM8B H-InvDB: TIMM8B

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for TIMM8B Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for TIMM8B Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for TIMM8B gene:
    Search GeneIP for patents involving TIMM8B

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 18 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 27 Apr 2013

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