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TIMM8B Gene

protein-coding   GIFtS: 53
GCID: GC11M111989

Translocase Of Inner Mitochondrial Membrane 8 Homolog B...

(Previous name: translocase of inner mitochondrial membrane 8 (yeast) homolog...)
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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Translocase Of Inner Mitochondrial Membrane 8 Homolog B (Yeast)1 2     TIM8B2 3
Mitochondrial Import Inner Membrane Translocase Subunit Tim8 B1 2     DDP-Like Protein2 3
Deafness Dystonia Protein 22 3     Translocase Of Inner Mitochondrial Membrane 8 (Yeast) Homolog B1
DDP22 3     DDPL3

External Ids:    HGNC: 118181   Entrez Gene: 265212   Ensembl: ENSG000001507797   OMIM: 6066595   UniProtKB: Q9Y5J93   

Export aliases for TIMM8B gene to outside databases

Previous GC identifers: GC11M114308 GC11M113467 GC11M111493 GC11M111461 GC11M107879


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for TIMM8B Gene:
This gene encodes a member of a well-conserved family of proteins with similarity to yeast Tim mitochondrial
import proteins. This gene is encoded by a nuclear gene and is transported into the intermembrane space of the
mitochondrion. When formed into complexes, these proteins guide membrane-spanning proteins across the
mitochondrial intermembrane space before they are added into the mitochondrial inner membrane. This gene is
adjacent to succinate dehydrogenase, subunit D (SDHD), in which mutations have been found in affected members of
families with hereditary paraganglioma.(provided by RefSeq, Aug 2009)

GeneCards Summary for TIMM8B Gene:
TIMM8B (translocase of inner mitochondrial membrane 8 homolog B (yeast)) is a protein-coding gene. An important paralog of this gene is TIMM8A.

UniProtKB/Swiss-Prot: TIM8B_HUMAN, Q9Y5J9
Function: Probable mitochondrial intermembrane chaperone that participates in the import and insertion of some
multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of
beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer
membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide
them through the mitochondrial intermembrane space (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000011.9  NC_018922.2  NT_033899.9  
Regulatory elements:
   Regulatory transcription factor binding sites in the TIMM8B gene promoter:
         AML1a   FOXO3   FOXD3   POU3F2 (N-Oct-5a)   POU3F2 (N-Oct-5b)   POU3F2   FOXO3b   RORalpha1   AREB6   Nkx6-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidTIMM8B promoter sequence
   Search Chromatin IP Primers for TIMM8B

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat TIMM8B


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 11q23.1-q23.2   Ensembl cytogenetic band:  11q23.1   HGNC cytogenetic band: 11q23.1-q23.2

TIMM8B Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TIMM8B gene location

GeneLoc information about chromosome 11         GeneLoc Exon Structure

GeneLoc location for GC11M111989:  view genomic region     (about GC identifiers)

Start:
111,955,524 bp from pter      End:
111,957,522 bp from pter
Size:
1,999 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: TIM8B_HUMAN, Q9Y5J9 (See protein sequence)
Recommended Name: Mitochondrial import inner membrane translocase subunit Tim8 B  
Size: 83 amino acids; 9344 Da
Subunit: Heterohexamer; possibly composed of 3 copies of TIMM8B and 3 copies of TIMM13, named soluble 70 kDa
complex. Associates with the TIM22 complex, whose core is composed of TIMM22 (By similarity)
Secondary accessions: B0YJA5 Q3KQS9 Q9UN04

Explore the universe of human proteins at neXtProt for TIMM8B: NX_Q9Y5J9

Explore proteomics data for TIMM8B at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys80
  • Modification sites at PhosphoSitePlus

  • See TIMM8B Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_036591.2  
    ENSEMBL proteins: 
     ENSP00000422122   ENSP00000421964   ENSP00000438455  
    Reactome Protein details: Q9Y5J9

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    1 InterPro protein domain:
     IPR004217 Tim10/DDP_fam_Znf

    Graphical View of Domain Structure for InterPro Entry Q9Y5J9

    ProtoNet protein and cluster: Q9Y5J9

    1 Blocks protein domain: IPB004217 Zn-finger

    UniProtKB/Swiss-Prot: TIM8B_HUMAN, Q9Y5J9
    Domain: The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial
    intermembrane space. However, during the transit of TIMM8B from cytoplasm into mitochondrion, the Cys residues
    probably coordinate zinc, thereby preventing folding and allowing its transfer across mitochondrial outer
    membrane (By similarity)
    Similarity: Belongs to the small Tim family


    Find genes that share domains with TIMM8B           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: TIM8B_HUMAN, Q9Y5J9
    Function: Probable mitochondrial intermembrane chaperone that participates in the import and insertion of some
    multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of
    beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer
    membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide
    them through the mitochondrial intermembrane space (By similarity)

         Genatlas biochemistry entry for TIMM8B:
    translocase of inner mitochondrial membrane 8 (yeast) homolog B,ubiquitously expressed,highly in cardiac and
    skeletal muscle,S cerevisiae Tim8p ortholog,component of the Tm complex

         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008270zinc ion binding TAS10552927
    GO:0046872metal ion binding ----
         
    Find genes that share ontologies with TIMM8B           About GenesLikeMe


    Phenotypes:
         1 GenomeRNAi human phenotype for TIMM8B:
     Increased gamma-H2AX phosphory 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for TIMM8B
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    miRNA
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    miRTarBase miRNAs that target TIMM8B:
    hsa-mir-124-3p (MIRT023062)

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    Selected qRT-PCR Assays for microRNAs that regulate TIMM8B (see all 9):
    hsa-miR-320a hsa-miR-3942-5p hsa-miR-513a-3p hsa-miR-320d hsa-miR-4255 hsa-miR-29c hsa-miR-29a hsa-miR-320b
    SwitchGear 3'UTR luciferase reporter plasmidTIMM8B 3' UTR sequence
    Inhib. RNA
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    TIM8B_HUMAN, Q9Y5J9: Mitochondrion inner membrane; Peripheral membrane protein; Intermembrane side (By
    similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    mitochondrion5
    cytosol3
    extracellular3
    nucleus2

    Gene Ontology (GO): 4 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005615extracellular space IDA--
    GO:0005739mitochondrion ----
    GO:0005743mitochondrial inner membrane IEA--
    GO:0042719mitochondrial intermembrane space protein transporter complex TAS10552927

    Find genes that share ontologies with TIMM8B           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for TIMM8B About    
    See pathways by source

    SuperPathContained pathways About
    1Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
    Metabolism of proteins0.30
    2Mitochondrial Protein Import
    Mitochondrial Protein Import


    Find genes that share SuperPaths with TIMM8B           About GenesLikeMe

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    1 Reactome Pathway for TIMM8B
        Mitochondrial protein import


        Pathway & Disease-focused RT2 Profiler PCR Array including TIMM8B: 
              Mitochondria in human mouse rat

    Interactions:

        Search GeneGlobe Interaction Network for TIMM8B

    1 Interacting protein for TIMM8B (Q9Y5J93) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    TIMM13Q9Y5L43I2D: score=2 
    About this table

    Gene Ontology (GO): 5 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006626protein targeting to mitochondrion TAS--
    GO:0007605sensory perception of sound TAS10552927
    GO:0015031protein transport ----
    GO:0044267cellular protein metabolic process TAS--
    GO:0072321chaperone-mediated protein transport TAS16387659

    Find genes that share ontologies with TIMM8B           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for TIMM8B (TIM8B)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for TIMM8B gene: 
    NM_012459.2  

    Unigene Cluster for TIMM8B:

    Translocase of inner mitochondrial membrane 8 homolog B (yeast)
    Hs.279915  [show with all ESTs]
    Unigene Representative Sequence: NR_028383
    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000504148 ENST00000509359(uc001pmy.3 uc001pmx.3) ENST00000507614
    ENST00000541231
    miRNA
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    hsa-miR-320a hsa-miR-3942-5p hsa-miR-513a-3p hsa-miR-320d hsa-miR-4255 hsa-miR-29c hsa-miR-29a hsa-miR-320b
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      QuantiTect SYBR Green Assays in human, mouse, rat TIMM8B
      QuantiFast Probe-based Assays in human, mouse, rat TIMM8B

    Additional mRNA sequence: 

    AF150087.1 AF152350.1 AF165967.1 AK025397.1 AK312169.1 BC000711.2 BC105986.1 BC106067.1 
    NR_028383.1 

    19 DOTS entries:

    DT.101983723  DT.86854195  DT.95138569  DT.92443760  DT.97859482  DT.97859481  DT.95178970  DT.120733807 
    DT.91973611  DT.101982480  DT.100651701  DT.95178994  DT.453563  DT.95178964  DT.100694767  DT.120733864 
    DT.101982479  DT.120733741  DT.120733838 

    Selected AceView cDNA sequences (see all 255):

    AI149558 AA086377 CA952824 BQ682388 F37171 AW204166 NM_012459 AA953258 
    AA777770 BU735382 AI660467 BG941989 CF541334 AA738223 AK025397 AF152350 
    BQ011753 AA441909 BE797491 AA348522 AI336038 AI815423 AW192353 AA442122 

    GeneLoc Exon Structure

    3 Alternative Splicing Database (ASD) splice patterns (SP) for TIMM8B    About this scheme

    ExUns: 1a · 1b ^ 2a · 2b ^ 3a · 3b · 3c
    SP1:                    -                     
    SP2:                                          
    SP3:              -     -                     


    ECgene alternative splicing isoforms for TIMM8B

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    TIMM8B expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GAGTTATGTT
    TIMM8B Expression
    About this image

    TIMM8B Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    TIMM8B Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.279915

    UniProtKB/Swiss-Prot: TIM8B_HUMAN, Q9Y5J9
    Tissue specificity: Ubiquitous, with highest expression in heart, kidney, liver and skeletal muscle

        Pathway & Disease-focused RT2 Profiler PCR Array including TIMM8B: 
              Mitochondria in human mouse rat

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TIMM8B

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals and fungi.

    Orthologs for TIMM8B gene from Selected species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Timm8b1 , 5 translocase of inner mitochondrial membrane 8 homolog more5
    translocase of inner mitochondrial membrane 8B1
    89.56(n)1
    97.59(a)1
      9 (27.75 cM)5
    300571  NM_013897.21  NP_038925.11 
     506039015 
    African clawed frog
    (Xenopus laevis)
    Amphibia BJ612182.12   -- 76.88(n)    BJ612182.1 
    zebrafish
    (Danio rerio)
    Actinopterygii Dr.150182 Transcribed sequence with moderate similarity to protein more 73.33(n)    CF543883.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta Tim81 Tim8 60.53(n)
    57.89(a)
      32081  NM_132485.4  NP_572713.1 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes TIM86
    Mitochondrial intermembrane space protein, forms a...
    30(a)
    1 → many
    X(676971-677234) YJR135W-A


    ENSEMBL Gene Tree for TIMM8B (if available)
    TreeFam Gene Tree for TIMM8B (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for TIMM8B gene
    TIMM8A2  
    2 SIMAP similar genes for TIMM8B using alignment to 3 protein entries:     TIM8B_HUMAN (see all proteins):
    TIMM8A    TIMM13

    Find genes that share paralogs with TIMM8B           About GenesLikeMe


    2 Pseudogenes.org Pseudogenes for TIMM8B
    PGOHUM00000248350 PGOHUM00000250087


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    1 SNPs for TIMM8B    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 11 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs3738992671,2
    ----111955523(+) TTGCC-/TTTTTTTT 3 -- spd1 cds1 ds50010--------

    HapMap Linkage Disequilibrium report for TIMM8B (111955524 - 111957522 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for TIMM8B:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2745077CNV Deletion23290073

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing TIMM8B
    DNA2.0 Custom Variant and Variant Library Synthesis for TIMM8B

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 606659    OMIM disorders: --

    1 disease from the University of Copenhagen DISEASES database for TIMM8B:
    Paraganglioma

    Find genes that share disorders with TIMM8B           About GenesLikeMe

    Genetic Association Database (GAD): TIMM8B
    Human Genome Epidemiology (HuGE) Navigator: TIMM8B (4 documents)

    Export disorders for TIMM8B gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for TIMM8B gene, integrated from 10 sources (see all 26):
    (articles sorted by number of sources associating them with TIMM8B)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The human family of deafness/dystonia peptide (DDP) related mitochondrial import proteins. (PubMed id 10552927)1, 2, 3 Jin H.... Vetrie D.L.P. (Genomics 1999)
    2. Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression. (PubMed id 20877624)1, 4 Hendrickson S.L....O'Brien S.J. (PLoS ONE 2010)
    3. Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. (PubMed id 20628086)1, 4 Bailey S.D....Anand S. (Diabetes Care 2010)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    5. The mitochondrial TIM22 preprotein translocase is highly conserved throughout the eukaryotic kingdom. (PubMed id 10611480)1, 2 Bauer M.F.... Hofmann S. (FEBS Lett. 1999)
    6. Pathway Analysis of ChIP-Seq-Based NRF1 Target Genes Suggests a Logical Hypothesis of their Involvement in the Pathogenesis of Neurodegenerative Diseases. (PubMed id 24250222)1 Satoh J....Yamamoto Y. (Gene Regul Syst Bio 2013)
    7. Proteome-wide identification of ubiquitylation sites by conjugation of engineered lysine-less ubiquitin. (PubMed id 22053931)1 Oshikawa K....Nakayama K.I. (J. Proteome Res. 2012)
    8. Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass. (PubMed id 23000965)1 Povlsen L.K....Choudhary C. (Nat. Cell Biol. 2012)
    9. Global landscape of HIV-human protein complexes. (PubMed id 22190034)1 JAoger S....Krogan N.J. (Nature 2012)
    10. Comparative large scale characterization of plant versus mammal proteins reveals similar and idiosyncratic N-I+-acetylation features. (PubMed id 22223895)2 Bienvenut W.V....Giglione C. (amp 2012)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 26521 HGNC: 11818 AceView: TIMM8B Ensembl:ENSG00000150779 euGenes: HUgn26521
    ECgene: TIMM8B H-InvDB: TIMM8B

    (According to HUGE)
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    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for TIMM8B Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for TIMM8B Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for TIMM8B gene:
    Search GeneIP for patents involving TIMM8B

    GeneCards and IP:
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