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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

TIMM44 Gene

protein-coding   GIFtS: 56
GCID: GC19M007991

translocase of inner mitochondrial membrane 44 homolog (yeast)

 Explore 1 disease affiliated with
TIMM44 via our new
 Human Malady Compendium 
Biological research products
for TIMM44
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
Translocase Of Inner Mitochondrial Membrane 44 Homolog (Yeast)1 2
TIM441 2 3
Mitochondrial Import Inner Membrane Translocase Subunit TIM442
Mitochondrial Inner Membrane Translocase2
MIMT443

External Ids:    HGNC: 173161   Entrez Gene: 104692   Ensembl: ENSG000001049807   OMIM: 6050585   UniProtKB: O436153   

Export aliases for TIMM44 gene to outside databases

Previous GC identifers: GC19M007950 GC19M008097 GC19M007897 GC19M007661


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: TIM44_HUMAN, O43615
Function: Essential component of the PAM complex, a complex required for the translocation of transit
peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. Recruits
mitochondrial HSP70 to drive protein translocation into the matrix using ATP as an energy source

Gene Wiki entry for TIMM44


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000019.9  NC_018930.1  NT_077812.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the TIMM44 gene promoter:
         Pax-2   FOXD1   Pax-2a   POU3F2 (N-Oct-5a)   POU3F2 (N-Oct-5b)   POU3F2   CHOP-10   HEN1   Pax-2b   Pax-4a   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidTIMM44 promoter sequence
   Search SABiosciences Chromatin IP Primers for TIMM44

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TIMM44


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 19p13.3-p13.2   Ensembl cytogenetic band:  19p13.2   HGNC cytogenetic band: 19p13.3-p13.2

TIMM44 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TIMM44 gene location

GeneLoc information about chromosome 19         GeneLoc Exon Structure

GeneLoc location for GC19M007991:  view genomic region     (about GC identifiers)

Start:
7,991,603 bp from pter      End:
8,008,708 bp from pter
Size:
17,106 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: TIM44_HUMAN, O43615 (See protein sequence)
Recommended Name: Mitochondrial import inner membrane translocase subunit TIM44 precursor  
Size: 452 amino acids; 51356 Da
Subunit: Probable component of the PAM complex at least composed of a mitochondrial HSP70 protein, GRPEL1 or GRPEL2,
TIMM44, TIMM16/PAM16 and TIMM14/DNAJC19 (By similarity). The complex interacts with the TIMM23 component of the TIM23
complex
Subcellular location: Mitochondrion inner membrane
1 PDB 3D structure from and Proteopedia for TIMM44:
2CW9 (3D)    
Secondary accessions: A8K0R9 D6W664 Q8N193

Explore the universe of human proteins at neXtProt for TIMM44: NX_O43615

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_O43615

  • TIMM44 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_006342.2  
    ENSEMBL proteins: 
     ENSP00000270538  
    Reactome Protein details: O43615
    Human Recombinant Protein Products: 
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    OriGene Protein Over-expression Lysate: TIMM44
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    Novus Biologicals TIMM44 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins
    Uscn Proteins for TIMM44

    Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005739mitochondrion IDA--
    GO:0005743mitochondrial inner membrane IDA10339406
    GO:0005744mitochondrial inner membrane presequence translocase complex IEA--
    GO:0005759mitochondrial matrix IDA10339406


    TIMM44 for ontologies           About GeneDecksing



    TIMM44 Antibody Products: 
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    Uscn Antibodies for TIMM44
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    Uscn ELISAs and CLIAs for TIMM44


    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    TIMM44 for domains           About GeneDecksing

    2 InterPro domains/families:
     IPR007379 Tim44-related/Ribosome_L45
     IPR017303 Tim44

    Graphical View of Domain Structure for InterPro Entry O43615

    ProtoNet protein and cluster: O43615

    1 Blocks protein family: IPB007379 Mitochondrial import inner membrane translocase

    UniProtKB/Swiss-Prot: TIM44_HUMAN, O43615
    Similarity: Belongs to the Tim44 family


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Function Summary:

         UniProtKB/Swiss-Prot: TIM44_HUMAN, O43615
    Function: Essential component of the PAM complex, a complex required for the translocation of transit
    peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. Recruits
    mitochondrial HSP70 to drive protein translocation into the matrix using ATP as an energy source

    miRNA
    Products:
        
    OriGene 3'-UTR Clone: TIMM44
    Browse MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat TIMM44
    1 QIAGEN miScript miRNA Assays for microRNA that regulate TIMM44:
    hsa-miR-1207-3p
    SwitchGear 3'UTR luciferase reporter plasmidTIMM44 3' UTR sequence
    Inhib. RNA
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    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for TIMM44 (see all 7)
    OriGene shRNA RFP: TIMM44
    OriGene siRNA: TIMM44
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TIMM44

    Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI12620389
    GO:0005524ATP binding IEA--
    GO:0015450P-P-bond-hydrolysis-driven protein transmembrane transporter activity IEA--
    GO:0051087chaperone binding ----


    TIMM44 for ontologies           About GeneDecksing


    1 GenomeRNAi human phenotype for TIMM44:
     Decreased influenza A/WSN/33 r 


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Mitochondrial Protein Import
    Mitochondrial Protein Import1.00
    2Asparagine N-linked glycosylation
    Metabolism of proteins0.15

    Pathway sources
    See GeneCards unified pathways
    Show all pathways


    2        Reactome Pathways for TIMM44
        Mitochondrial Protein Import
    Metabolism of proteins



    TIMM44 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for TIMM44

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/57 Interacting proteins for TIMM44 (O436151, 3 ENSP000002705384) via UniProtKB, MINT, STRING, and/or I2D (see all 57)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ARAFP103981, 3, ENSP000003662444EBI-861737,EBI-365961 I2D: score=5 STRING: ENSP00000366244
    HSPA9P386463, ENSP000002971854I2D: score=5 STRING: ENSP00000297185
    MOGSQ137243, ENSP000002336164I2D: score=5 STRING: ENSP00000233616
    TIMM17BO608303, ENSP000003657664I2D: score=2 STRING: ENSP00000365766
    HSPD1P108093, ENSP000003400194I2D: score=1 STRING: ENSP00000340019
    About this table

    Gene Ontology (GO): 3 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006626protein targeting to mitochondrion TAS--
    GO:0006886intracellular protein transport ----
    GO:0044267cellular protein metabolic process TAS--


    TIMM44 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    TIMM44 for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for TIMM44
    1 Novoseek chemical compound relationship for TIMM44 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    atp 11.2 3 10913171 (2), 11937760 (1)

    Search CenterWatch for drugs/clinical trials and news about TIMM44 / TIM44 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for TIMM44 gene: 
    NM_006351.3  

    Unigene Cluster for TIMM44:

    Translocase of inner mitochondrial membrane 44 homolog (yeast)
    Hs.465784  [show with all ESTs]
    Unigene Representative Sequence: CR627419
    1 Ensembl transcript including schematic representation, and UCSC links where relevant:
    ENST00000270538(uc002miz.3 uc010dvx.2)

    miRNA
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    OriGene 3'-UTR Clone: TIMM44
    Browse OriGene MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat TIMM44
    1 QIAGEN miScript miRNA Assays for microRNA that regulate TIMM44:
    hsa-miR-1207-3p
    SwitchGear 3'UTR luciferase reporter plasmidTIMM44 3' UTR sequence
    Inhib. RNA
    Products:
         
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    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for TIMM44 (see all 7)
    OriGene shRNA RFP: TIMM44
    OriGene siRNA: TIMM44
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TIMM44
    Clone
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    Primer
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TIMM44
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TIMM44

    Additional cDNA sequence: 

    AF026030.1 AF041254.1 AK223062.1 AK289634.1 AK309415.1 BC033628.1 CR627419.1 X58234.1 

    21 DOTS entries:

    DT.100820239  DT.442574  DT.100820250  DT.91877673  DT.92047090  DT.100820246  DT.100820248  DT.100757924 
    DT.100820241  DT.100820240  DT.121452024  DT.444529  DT.95202295  DT.100673009  DT.121452045  DT.97808770 
    DT.97861007  DT.121413194  DT.121413268  DT.91668770  DT.95344133 

    24/355 AceView cDNA sequences (see all 355):

    AI589670 AI923270 BM750692 BM742224 CR597878 CA489444 BX364558 CB152340 
    BP351709 CR595021 BM770335 T28125 NM_006351 F27317 BQ072969 BM796411 
    AK098834 AA477833 BM724653 BM069486 BM756736 BM743906 AI697206 BQ649769 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TIMM44 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: GGCAAGATGA

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)

    About this image
    See TIMM44 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for TIMM44

    SOURCE GeneReport for Unigene cluster: Hs.465784
        SABiosciences Expression via Pathway-Focused PCR Array including TIMM44: 
              Mitochondria in human mouse rat

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TIMM44

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for TIMM44 gene from 9/31 species (see all 31)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Timm441 , 5 translocase of inner mitochondrial membrane 441, 5 84.59(n)1
    89.6(a)1
      8 (1.99 cM)5
    218561  NM_011592.21  NP_035722.21 
     42597315 
    chicken
    (Gallus gallus)
    Aves TIMM441 translocase of inner mitochondrial membrane 44 homolog more 73.92(n)
    83.41(a)
      420053  XM_418174.3  XP_418174.2 
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.138802 Xenopus laevis transcribed sequence with moderate similarity more 73.92(n)    48048821 
    zebrafish
    (Danio rerio)
    Actinopterygii LOC1005379101 mitochondrial import inner membrane translocase subunit more 73.68(n)
    83.21(a)
      100537910  XM_003200953.1  XP_003201001.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG117791 CG11779 59.71(n)
    52.67(a)
      42298  NM_142529.3  NP_650786.2 
    worm
    (Caenorhabditis elegans)
    Secernentea T09B4.91 , 3 Protein T09B4.91 43(a)3
    50.26(n)1
    44.3(a)1
      I(6186307-6188905)3
    1723021  NM_059379.21  NP_491780.11 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes TIM44(YIL022W)4
    TIM441
    Essential component of the Translocase of the Inner more4
    Tim44p1
    45.67(n)1
    30.56(a)1
      9(311165-312460)4
    8547901, 4  NP_012242.11, 4 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons TIM44-21 translocase inner membrane subunit 44-2 39.93(n)
    26.32(a)
      818180  NM_129166.4  NP_181151.3 
    rice
    (Oryza sativa)
    Liliopsida Os07g04097001 hypothetical protein 39.74(n)
    29.66(a)
      4343001  NM_001065978.1  NP_001059443.1 


    ENSEMBL Gene Tree for TIMM44 (if available)
    TreeFam Gene Tree for TIMM44 (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/443 NCBI SNPs in TIMM44 are shown (see all 443    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 19 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs739239271,2
    C,--7991193(+) ACGACT/CTCGCC 2 -- int1 us2k11Minor allele frequency- C:0.00WA 2
    rs729978731,2
    C,F,--7991261(+) CCTGTG/ACCTGC 2 -- int1 us2k12Minor allele frequency- A:0.28NA EA 240
    rs1167289711,2
    F,--7991293(+) CACTCG/CAGACT 2 -- int1 us2k11Minor allele frequency- C:0.06WA 118
    rs1834945451,2
    --7991296(+) TCGAGA/GCTCCC 2 -- us2k1 int10--------
    rs1440275771,2
    C,--7991301(+) ACTCC-/CTGTTTG 2 -- int1 us2k10--------
    rs356721161,2
    C,F,H,--7991334(+) AAAACA/GCTCAT 2 -- int1 us2k115Minor allele frequency- G:0.04NS EA NA 2096
    rs1469003651,2
    --7991358(+) CTCCCA/CCGGCC 2 -- int1 us2k10--------
    rs1479685631,2
    --7991620(+) ATTCGA/GTGTTT 2 -- us2k1 ut310--------
    rs1407078721,2
    --7991659(+) CAAGAA/TGGAAG 2 -- ut31 us2k10--------
    rs78991,2
    C,F,A,H,--7991679(+) AAAATT/AAAAAA 2 -- us2k1 ut319Minor allele frequency- A:0.31MN NS EA CSA WA 1026

    HapMap Linkage Disequilibrium report for TIMM44 (7991603 - 8008708 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for TIMM44: --
    Human Gene Mutation Database (HGMD): TIMM44

    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing TIMM44
    DNA2.0 Custom Variant and Variant Library Synthesis for TIMM44

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    TIMM44 for disorders           About GeneDecksing

    OMIM gene information: 605058    OMIM disorders: --

    1 disease for TIMM44:    About MalaCards
    malaria

    1 Novoseek disease relationship for TIMM44 gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    shock 41 3 16107694 (1), 10913171 (1), 15218029 (1)

    Human Genome Epidemiology (HuGE) Navigator: TIMM44 (1 document)

    Export disorders for TIMM44 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for TIMM44 gene, integrated from 9 sources (see all 30):
    (articles sorted by number of sources associating them with TIMM44)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Genetic and structural characterization of the human mitochondrial inner membrane translocase. (PubMed id 10339406)1, 2, 3, 9 Bauer M.F.... Hofmann S. (1999)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    3. Isoform-specific localization of A-RAF in mitochondria. (PubMed id 10848612)1, 3 Yuryev A.... Wennogle L.P. (2000)
    4. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
    5. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
    6. A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
    7. System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. (PubMed id 21406692)2 Rigbolt K.T....Blagoev B. (2011)
    8. Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)
    9. Proteome analysis of the thalamus and cerebrospinal f luid reveals glycolysis dysfunction and potential biomarkers candidates for sch izophrenia. (PubMed id 20471030)1 Martins-de-Souza D....Turck C.W. (2010)
    10. Role of Magmas in protein transport and human mitocho ndria biogenesis. (PubMed id 20053669)1 Sinha D....D'Silva P. (2010)

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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 10469 HGNC: 17316 AceView: TIMM44andCTXN1 Ensembl:ENSG00000104980 euGenes: HUgn10469
    ECgene: TIMM44 H-InvDB: TIMM44

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for TIMM44 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for TIMM44 Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for TIMM44 gene:
    Search GeneIP for patents involving TIMM44

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences),
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