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Aliases for TIMM23B Gene

Aliases for TIMM23B Gene

  • Translocase Of Inner Mitochondrial Membrane 23 Homolog B (Yeast) 2 3
  • Putative Mitochondrial Import Inner Membrane Translocase Subunit Tim23B 3
  • BA592B15.7 3
  • TIMM23 3

External Ids for TIMM23B Gene

Summaries for TIMM23B Gene

GeneCards Summary for TIMM23B Gene

TIMM23B (Translocase Of Inner Mitochondrial Membrane 23 Homolog B (Yeast)) is a Protein Coding gene. GO annotations related to this gene include P-P-bond-hydrolysis-driven protein transmembrane transporter activity.

UniProtKB/Swiss-Prot for TIMM23B Gene

  • May participate in the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. the PAM complex (By similarity).

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TIMM23B Gene

Genomics for TIMM23B Gene

Genomic Location for TIMM23B Gene

Start:
49,942,033 bp from pter
End:
49,974,957 bp from pter
Size:
32,925 bases
Orientation:
Plus strand

Genomic View for TIMM23B Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for TIMM23B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TIMM23B Gene

No data available for Regulatory Elements for TIMM23B Gene

Proteins for TIMM23B Gene

  • Protein details for TIMM23B Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q5SRD1-TI23B_HUMAN
    Recommended name:
    Putative mitochondrial import inner membrane translocase subunit Tim23B
    Protein Accession:
    Q5SRD1
    Secondary Accessions:
    • Q5SRD2

    Protein attributes for TIMM23B Gene

    Size:
    257 amino acids
    Molecular mass:
    28048 Da
    Quaternary structure:
    No Data Available

neXtProt entry for TIMM23B Gene

Proteomics data for TIMM23B Gene at MOPED

Post-translational modifications for TIMM23B Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for TIMM23B Gene

No data available for DME Specific Peptides for TIMM23B Gene

Domains for TIMM23B Gene

Protein Domains for TIMM23B Gene

UniProtKB/Swiss-Prot:

TI23B_HUMAN
Family:
  • Belongs to the Tim17/Tim22/Tim23 family.:
    • Q5SRD1
genes like me logo Genes that share domains with TIMM23B: view

No data available for Gene Families for TIMM23B Gene

Function for TIMM23B Gene

Molecular function for TIMM23B Gene

UniProtKB/Swiss-Prot Function: May participate in the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. the PAM complex (By similarity).

Gene Ontology (GO) - Molecular Function for TIMM23B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003674 molecular_function ND --
GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity IEA --
genes like me logo Genes that share ontologies with TIMM23B: view

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for TIMM23B Gene

Localization for TIMM23B Gene

Subcellular locations from UniProtKB/Swiss-Prot for TIMM23B Gene

Mitochondrion inner membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for TIMM23B Gene COMPARTMENTS Subcellular localization image for TIMM23B gene
Compartment Confidence
mitochondrion 5
cytosol 2
nucleus 2

Gene Ontology (GO) - Cellular Components for TIMM23B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005575 cellular_component ND --
GO:0005744 mitochondrial inner membrane presequence translocase complex IEA --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with TIMM23B: view

Pathways for TIMM23B Gene

SuperPathways for TIMM23B Gene

No Data Available

Interacting Proteins for TIMM23B Gene

Gene Ontology (GO) - Biological Process for TIMM23B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006886 intracellular protein transport IEA --
GO:0008150 biological_process ND --
GO:0071806 protein transmembrane transport IEA --
genes like me logo Genes that share ontologies with TIMM23B: view

No data available for Pathways by source for TIMM23B Gene

Transcripts for TIMM23B Gene

mRNA/cDNA for TIMM23B Gene

(7) REFSEQ mRNAs :
(4) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for TIMM23B Gene

No ASD Table

Relevant External Links for TIMM23B Gene

GeneLoc Exon Structure for
TIMM23B
ECgene alternative splicing isoforms for
TIMM23B

Expression for TIMM23B Gene

mRNA expression in normal human tissues for TIMM23B Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for TIMM23B Gene

genes like me logo Genes that share expressions with TIMM23B: view

Orthologs for TIMM23B Gene

This gene was present in the common ancestor of animals.

Orthologs for TIMM23B Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia TIMM23 37
  • 82 (a)
OneToMany
TIMM23B 36
  • 97.87 (n)
  • 96.28 (a)
cow
(Bos Taurus)
Mammalia TIMM23 37
  • 82 (a)
OneToMany
dog
(Canis familiaris)
Mammalia -- 37
  • 96 (a)
OneToMany
mouse
(Mus musculus)
Mammalia Gm10273 37
  • 79 (a)
ManyToMany
Timm23 37
  • 79 (a)
ManyToMany
oppossum
(Monodelphis domestica)
Mammalia -- 37
  • 73 (a)
OneToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 37
  • 94 (a)
OneToMany
chicken
(Gallus gallus)
Aves -- 37
  • 75 (a)
OneToMany
lizard
(Anolis carolinensis)
Reptilia -- 37
  • 73 (a)
OneToMany
zebrafish
(Danio rerio)
Actinopterygii LOC100535463 36
  • 72.11 (n)
  • 83.01 (a)
timm23 37
  • 63 (a)
OneToMany
fruit fly
(Drosophila melanogaster)
Insecta CG40042 37
  • 36 (a)
OneToMany
worm
(Caenorhabditis elegans)
Secernentea timm-23 37
  • 18 (a)
OneToMany
sea squirt
(Ciona savignyi)
Ascidiacea CSA.5979 37
  • 23 (a)
OneToMany
Species with no ortholog for TIMM23B:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)

Evolution for TIMM23B Gene

ENSEMBL:
Gene Tree for TIMM23B (if available)
TreeFam:
Gene Tree for TIMM23B (if available)

Paralogs for TIMM23B Gene

Selected SIMAP similar genes for TIMM23B Gene using alignment to 5 proteins:

genes like me logo Genes that share paralogs with TIMM23B: view

No data available for Paralogs for TIMM23B Gene

Variants for TIMM23B Gene

Sequence variations from dbSNP and Humsavar for TIMM23B Gene

SNP ID Clin Chr 10 pos Sequence Context AA Info Type MAF
rs2338086 -- 49,965,544(-) TCTCA(C/T)TTCAT intron-variant
rs2805282 -- 49,966,374(+) gaaaC(A/G/T)aaatg intron-variant
rs2805310 -- 49,969,225(+) agcca(A/G)tgtgg intron-variant
rs2805321 -- 49,969,491(+) aatgg(A/G)cagat intron-variant
rs7896643 -- 49,970,653(+) ccgtc(C/T)gggag intron-variant

Relevant External Links for TIMM23B Gene

HapMap Linkage Disequilibrium report
TIMM23B

No data available for Structural Variations from Database of Genomic Variants (DGV) for TIMM23B Gene

Disorders for TIMM23B Gene

No disorders were found for TIMM23B Gene.

No data available for UniProtKB/Swiss-Prot for TIMM23B Gene

Publications for TIMM23B Gene

  1. The DNA sequence and comparative analysis of human chromosome 10. (PMID: 15164054) Deloukas P. … Rogers J. (Nature 2004) 3 4
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3
  3. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PMID: 17207965) Lamesch P. … Vidal M. (Genomics 2007) 3
  4. Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. (PMID: 21139048) Danielsen J.M. … Nielsen M.L. (Mol. Cell Proteomics 2011) 3
  5. Systematic and quantitative assessment of the ubiquitin-modified proteome. (PMID: 21906983) Kim W. … Gygi S.P. (Mol. Cell 2011) 3

Products for TIMM23B Gene

Sources for TIMM23B Gene

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