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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

TIMM21 Gene

protein-coding   GIFtS: 46
GCID: GC18P071816

Translocase Of Inner Mitochondrial Membrane 21 Homolog (Yeast)

(Previous name: chromosome 18 open reading frame 55)
(Previous symbol: C18orf55)
  Search for TIMM21
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Translocase Of Inner Mitochondrial Membrane 21 Homolog (Yeast)1 2
C18orf551 2
TIM21-Like Protein, Mitochondrial2 3
Chromosome 18 Open Reading Frame 551
TIM212
Mitochondrial Import Inner Membrane Translocase Subunit Tim212

External Ids:    HGNC: 250101   Entrez Gene: 290902   Ensembl: ENSG000000753367   OMIM: 6151805   UniProtKB: Q9BVV73   

Export aliases for TIMM21 gene to outside databases


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for TIMM21 Gene: 
TIMM21 (translocase of inner mitochondrial membrane 21 homolog (yeast)) is a protein-coding gene. Among its related super-pathways are Post-translational protein modification. GO annotations related to this gene include molecular_function.

UniProtKB/Swiss-Prot: TIM21_HUMAN, Q9BVV7
Function: Participates in the translocation of transit peptide-containing proteins across the mitochondrial inner
membrane. Also required for assembly of mitochondrial respiratory chain complex I and complex IV as component of
some MITRAC complex, a cytochrome c oxidase (COX) assembly intermediate complex. TIM21 probably shuttles between
the presequence translocase and respiratory-chain assembly intermediates in a process that promotes incorporation
of early nuclear-encoded subunits into these complexes




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000018.9  NT_025028.14  NC_018929.2  
Regulatory elements:
   Search SABiosciences Regulatory transcription factor binding sites for TIMM21
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search SABiosciences Chromatin IP Primers for TIMM21

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TIMM21


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 18q22.3   Ensembl cytogenetic band:  18q22.3   HGNC cytogenetic band: 18q22.3

TIMM21 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TIMM21 gene location

GeneLoc information about chromosome 18         GeneLoc Exon Structure

GeneLoc location for GC18P071816:  view genomic region     (about GC identifiers)

Start:
71,815,746 bp from pter      End:
71,826,204 bp from pter
Size:
10,459 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: TIM21_HUMAN, Q9BVV7 (See protein sequence)
Recommended Name: Mitochondrial import inner membrane translocase subunit Tim21 precursor  
Size: 248 amino acids; 28202 Da
Subunit: Component of the TIM23 complex. Component of some MITRAC complex
Subcellular location: Mitochondrion membrane; Single-pass membrane protein (Potential)
Secondary accessions: Q9P010

Explore the universe of human proteins at neXtProt for TIMM21: NX_Q9BVV7

Explore proteomics data for TIMM21 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q9BVV7

  • TIMM21 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    TIMM21 Protein Expression
    REFSEQ proteins: NP_054896.2  
    ENSEMBL proteins: 
     ENSP00000169551   ENSP00000462028   ENSP00000464228  
    Reactome Protein details: Q9BVV7
    Human Recombinant Protein Products for TIMM21: 
    Browse Purified and Recombinant Proteins at EMD Millipore
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    Browse OriGene Protein Over-expression Lysates
    OriGene Custom MassSpec 
    OriGene Custom Protein Services for TIMM21
    GenScript Custom Purified and Recombinant Proteins Services for TIMM21
    Novus Biologicals TIMM21 Protein
    Novus Biologicals TIMM21 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Browse Proteins at Cloud-Clone Corp. 

    Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005575cellular_component ND--
    GO:0005739mitochondrion ----
    GO:0005744mitochondrial inner membrane presequence translocase complex IDA--
    GO:0016021integral to membrane IEA--

    TIMM21 for ontologies           About GeneDecksing



    TIMM21 Antibody Products: 
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    Novus Biologicals TIMM21 Antibodies
    Abcam antibodies for TIMM21
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    Assay Products for TIMM21: 
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    GenScript Custom Assay Services for TIMM21
    Browse Enzo Life Sciences for kits & assays
    Browse ELISAs at Cloud-Clone Corp. 
    Browse CLIAs at Cloud-Clone Corp.


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    1 InterPro protein domain:
     IPR013261 Tim21

    Graphical View of Domain Structure for InterPro Entry Q9BVV7

    ProtoNet protein and cluster: Q9BVV7

    UniProtKB/Swiss-Prot: TIM21_HUMAN, Q9BVV7
    Similarity: Belongs to the TIM21 family


    TIMM21 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: TIM21_HUMAN, Q9BVV7
    Function: Participates in the translocation of transit peptide-containing proteins across the mitochondrial inner
    membrane. Also required for assembly of mitochondrial respiratory chain complex I and complex IV as component of
    some MITRAC complex, a cytochrome c oxidase (COX) assembly intermediate complex. TIM21 probably shuttles between
    the presequence translocase and respiratory-chain assembly intermediates in a process that promotes incorporation
    of early nuclear-encoded subunits into these complexes

         Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003674molecular_function ND--
    GO:0005515protein binding IPI--
         
    TIMM21 for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for TIMM21 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for TIMM21

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for TIMM21 
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    miRNA
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    Search QIAGEN for miScript miRNA Assays for microRNAs that regulate TIMM21
    SwitchGear 3'UTR luciferase reporter plasmidTIMM21 3' UTR sequence
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for TIMM21
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    Gene Editing
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    OriGene ORF clones in mouse, rat for TIMM21
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    GenScript Custom all cDNA clones Services for TIMM21
    Sino Biological Human cDNA Clone for TIMM21
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TIMM21
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TIMM21
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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TIMM21


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for TIMM21 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Asparagine N-linked glycosylation
    Metabolism of proteins0.35
    2Mitochondrial Protein Import
    Mitochondrial Protein Import

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways



    2        Reactome Pathways for TIMM21
        Mitochondrial Protein Import
    Metabolism of proteins



    TIMM21 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for TIMM21

    STRING Interaction Network Preview (showing 5 interactants - click image to see 21)

    5/262 Interacting proteins for TIMM21 (Q9BVV71, 2, 3 ENSP000001695514) via UniProtKB, MINT, STRING, and/or I2D (see all 262)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    PMPCBO754392, ENSP000002492694MINT-8079030 STRING: ENSP00000249269
    PMPCAQ107132, ENSP000003607824MINT-8079030 STRING: ENSP00000360782
    ICT1Q141972, ENSP000003015854MINT-8079030 STRING: ENSP00000301585
    GRPEL1Q9HAV72, ENSP000002649544MINT-8079030 STRING: ENSP00000264954
    HSPA9P386462, ENSP000002971854MINT-8079030 STRING: ENSP00000297185
    About this table

    Gene Ontology (GO): 5 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006626protein targeting to mitochondrion TAS--
    GO:0030150protein import into mitochondrial matrix IMP--
    GO:0032981mitochondrial respiratory chain complex I assembly IMP--
    GO:0033617mitochondrial respiratory chain complex IV assembly IMP--
    GO:0044267cellular protein metabolic process TAS--

    TIMM21 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for TIMM21 (TIM21)

    Search CenterWatch for drugs/clinical trials and news about TIMM21 / TIM21

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for TIMM21 gene: 
    NM_014177.2  

    Unigene Cluster for TIMM21:

    Translocase of inner mitochondrial membrane 21 homolog (yeast)
    Hs.532835  [show with all ESTs]
    Unigene Representative Sequence: NM_014177
    6 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000169551(uc010dqr.1) ENST00000580087 ENST00000577952 ENST00000581467
    ENST00000584925 ENST00000579071
    miRNA
    Products:
         
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    Search QIAGEN for miScript miRNA Assays for microRNAs that regulate TIMM21
    SwitchGear 3'UTR luciferase reporter plasmidTIMM21 3' UTR sequence
    Inhib. RNA
    Products:
         
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    Clone
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    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TIMM21
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    Primer
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    OriGene qPCR primer pairs and template standards for TIMM21
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TIMM21
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TIMM21

    Additional mRNA sequence: 

    AF161503.1 AK289923.1 AK313936.1 BC000892.1 

    8 DOTS entries:

    DT.440786  DT.92432925  DT.95105550  DT.121090116  DT.92432928  DT.100695354  DT.121090102  DT.121090117 

    24/183 AceView cDNA sequences (see all 183):

    CB161092 BC000892 BM995420 BG944743 BG820086 BQ431656 AI082620 BM855567 
    F05238 AI918543 Z38776 AI417557 AA451896 AI985190 BE045352 AI863627 
    CR620926 AW779657 T32827 AI627948 BQ183303 T30959 Z42597 BP369147 

    GeneLoc Exon Structure

    5 Alternative Splicing Database (ASD) splice patterns (SP) for TIMM21    About this scheme

    ExUns: 1a · 1b ^ 2a · 2b ^ 3a · 3b · 3c ^ 4 ^ 5 ^ 6a · 6b · 6c
    SP1:                          -           -                                 
    SP2:                          -           -                                 
    SP3:                                      -                                 
    SP4:                          -                                             
    SP5:                                                                        


    ECgene alternative splicing isoforms for TIMM21

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TIMM21 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TAAATAAAGG
    TIMM21 Expression
    About this image


    See TIMM21 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for TIMM21

    SOURCE GeneReport for Unigene cluster: Hs.532835
        SABiosciences Custom PCR Arrays for TIMM21
    Primer
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TIMM21

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for TIMM21 gene from 7/15 species (see all 15)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Timm211 , 5 RIKEN cDNA 1700034H14 gene5
    tranlocase of inner mitochondrial membrane 211
    78.1(n)1
    70.25(a)1
      18 (57.53 cM)5
    671051  NM_025969.41  NP_080245.11 
     849472945 
    chicken
    (Gallus gallus)
    Aves C2H18orf551 chromosome 2 open reading frame, human C18orf55 73.33(n)
    72.57(a)
      421016  XM_419102.3  XP_419102.2 
    lizard
    (Anolis carolinensis)
    Reptilia TIMM216
    Uncharacterized protein
    54(a)
    1 ↔ 1
    4(49007743-49019165)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.108542 Xenopus laevis transcribed sequence with weak similarity more 79.54(n)    BX853815.1 
    zebrafish
    (Danio rerio)
    Actinopterygii LOC5603691 TIM21-like protein, mitochondrial-like 67.44(n)
    65.12(a)
      560369  XM_683774.3  XP_688866.2 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG73821 CG7382 48.59(n)
    39.76(a)
      33772  NM_135085.2  NP_608929.1 
    worm
    (Caenorhabditis elegans)
    Secernentea F56B3.111 Protein F56B3.11 43.52(n)
    33.12(a)
      176907  NM_067590.3  NP_499991.1 


    ENSEMBL Gene Tree for TIMM21 (if available)
    TreeFam Gene Tree for TIMM21 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for TIMM21 gene
    1 SIMAP similar gene for TIMM21 using alignment to 3 protein entries:     TIM21_HUMAN (see all proteins):
    C18orf55

    TIMM21 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/239 SNPs in TIMM21 are shown (see all 239)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 18 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0523064
    ----see VAR_0523062 G S mis40--------
    rs734765811,2
    C--71817161(+) TCAGAC/GGTGAC 1 -- int14Minor allele frequency- G:0.14WA NA EA 360
    rs734765821,2
    C--71817201(+) GCAACA/GTTCCC 1 -- int13Minor allele frequency- G:0.20WA EA 240
    rs801173301,2
    C,F--71817233(+) CAGAAT/GTCAAA 1 -- int13Minor allele frequency- G:0.09WA NA EA 358
    rs734765851,2
    C--71817239(+) TCAAAC/GAGGCC 1 -- int14Minor allele frequency- G:0.14WA NA EA 360
    rs563091471,2
    C,F--71817305(+) ATGTCT/CTGGCA 1 -- int19Minor allele frequency- C:0.37WA NA CSA EA 368
    rs1491119131,2
    --71817311(+) TGGCAC/TGCCCC 1 -- int10--------
    rs1421440581,2
    C--71817341(+) GGCTCA/GTGTGT 1 -- int10--------
    rs99488051,2
    C,F,A,H--71817485(+) ATTCTC/GCTGAA 1 -- int123Minor allele frequency- G:0.15NS EA NA WA 2762
    rs99488221,2
    C,F,H--71817538(+) atgtcC/Gtatat 1 -- int18Minor allele frequency- G:0.14NS EA WA NA 780

    HapMap Linkage Disequilibrium report for TIMM21 (71815746 - 71826204 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for TIMM21: --
    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing TIMM21
    DNA2.0 Custom Variant and Variant Library Synthesis for TIMM21

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    TIMM21 for disorders           About MalaCards
    OMIM gene information: 615180    OMIM disorders: --


    TIMM21 for disorders           About GeneDecksing


    Export disorders for TIMM21 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for TIMM21 gene integrated from 9 sources:
    (articles sorted by number of sources associating them with TIMM21)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells. (PubMed id 11042152)1, 2, 3 Zhang Q.-H.... Chen Z. (2000)
    2. MITRAC links mitochondrial protein translocation to respiratory-chain assembly and translational regulation. (PubMed id 23260140)1, 2 Mick D.U.... Rehling P. (2012)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    4. Inhibition of UBE2D3 expression attenuates radiosensit ivity of MCF-7 human breast cancer cells by increasing hTERT expression and acti vity. (PubMed id 23741361)1 Wang W....Zhou Y. (2013)
    5. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
    6. Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)
    7. A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
    8. Genetic variants in nuclear-encoded mitochondrial gen es influence AIDS progression. (PubMed id 20877624)1 Hendrickson S.L....O'Brien S.J. (2010)
    9. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 29090 HGNC: 25010 AceView: HSPC154 Ensembl:ENSG00000075336 euGenes: HUgn29090
    ECgene: TIMM21 H-InvDB: TIMM21

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for TIMM21 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for TIMM21 gene:
    Search GeneIP for patents involving TIMM21

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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