Aliases for TIMM10 Gene
- Translocase Of Inner Mitochondrial Membrane 10 2 3 5
- TIM10 3 4
- Translocase Of Inner Mitochondrial Membrane 10 (Yeast) Homolog 2
- Translocase Of Inner Mitochondrial Membrane 10 Homolog (Yeast) 2
- Mitochondrial Import Inner Membrane Translocase Subunit Tim10 3
- Translocase Of Inner Mitochondrial Membrane 10 Homolog 3
- TIMM10A 3
- TIM10A 3
External Ids for TIMM10 Gene
Previous GeneCards Identifiers for TIMM10 Gene
The mitochondrial protein encoded by this gene belongs to a family of evolutionarily conserved proteins that are organized in heterooligomeric complexes in the mitochondrial intermembrane space. These proteins mediate the import and insertion of hydrophobic membrane proteins into the mitochondrial inner membrane, functioning as intermembrane space chaperones for the highly insoluble carrier proteins. [provided by RefSeq, Nov 2011]
GeneCards Summary for TIMM10 Gene
TIMM10 (Translocase Of Inner Mitochondrial Membrane 10) is a Protein Coding gene. Diseases associated with TIMM10 include Mitochondrial Metabolism Disease. Among its related pathways are Metabolism of proteins and Mitochondrial protein import. Gene Ontology (GO) annotations related to this gene include protein homodimerization activity and chaperone binding.
UniProtKB/Swiss-Prot for TIMM10 Gene
Mitochondrial intermembrane chaperone that participates in the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. May also be required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.