TIGD7 Gene
protein-coding GIFtS: 43
GCID: GC16M003340
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|
tigger transposable element derived 7
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Aliases
for TIGD7 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Tigger Transposable Element Derived 71 2 | | Sancho1 2 | | Tigger Transposable Element-Derived Protein 72 | | SANCHO5 |
Export aliases for TIGD7 gene to outside databasesPrevious GC identifers: GC16M003361 GC16M003349 GC16M003288 |
Summaries
for TIGD7 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for TIGD7:
The protein encoded by this gene belongs to the tigger subfamily of the pogo superfamily of DNA-mediated transposons inhumans. These proteins are related to DNA transposons found in fungi and nematodes, and more distantly to the Tc1 andmariner transposases. They are also very similar to the major mammalian centromere protein B. The exact function ofthis gene is not known. (provided by RefSeq, Jul 2008)
|
Genomic Views
for TIGD7 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000016.9 NC_018927.1 NT_010393.16
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the TIGD7 gene promoter:
C/EBPbeta FOXF2 FOXL1 MZF-1 POU2F1 POU2F1a FOXO4 FOXO1
Other transcription factors
Search SABiosciences Chromatin IP Primers for TIGD7
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TIGD7 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 16p13.3 Ensembl cytogenetic band: 16p13.3 HGNC cytogenetic band: 16p13.11TIGD7 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 16 GeneLoc Exon Structure GeneLoc location for GC16M003340: view genomic region
(about GC identifiers)
Start:
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3,348,832 bp from pter |
End:
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3,355,729 bp from pter |
Size:
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6,898 bases |
Orientation:
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minus strand |
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Proteins
for TIGD7 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: TIGD7_HUMAN, Q6NT04 (See
protein sequence)Recommended Name: Tigger transposable element-derived protein 7 Size: 549 amino acids; 63236 Da
Subcellular location: Nucleus (Probable)
Secondary accessions: Q9BXZ0Alternative splicing: 2 isoforms: Q6NT04-1 Q6NT04-2 Explore the universe of human proteins at neXtProt for TIGD7: NX_Q6NT04
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q6NT04
TIGD7 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_149985.2
ENSEMBL proteins: ENSP00000380071 ENSP00000459534 ENSP00000268674
Human Recombinant Protein Products for TIGD7:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005634 | nucleus |
IEA | -- |
TIGD7 for ontologies About GeneDecksing
TIGD7 Antibody Products:
Assay Products for TIGD7: |
Protein
Domains /
Families
for TIGD7 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
TIGD7 for domains About GeneDecksing
4 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q6NT04ProtoNet protein and cluster: Q6NT04 1 Blocks protein family: IPB004875 CENP-B protein
UniProtKB/Swiss-Prot: TIGD7_HUMAN, Q6NT04Similarity: Belongs to the tigger transposable element derived protein familySimilarity: Contains 1 DDE domainSimilarity: Contains 1 HTH CENPB-type DNA-binding domainSimilarity: Contains 1 HTH psq-type DNA-binding domain |
Function
for TIGD7 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0003677 | DNA binding |
IEA | -- |
TIGD7 for ontologies About GeneDecksing
Animal Models:
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TIGD7
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TIGD7
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
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Synthesis Service for TIGD7 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TIGD7 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TIGD7 |
|
Pathways & Interactions
for TIGD7 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for TIGD7
STRING Interaction
Network Preview (showing 1 interactants - click image to see more details)
1 Interacting protein for TIGD7 (ENSP000002686744) via UniProtKB, MINT, STRING, and/or I2DAbout this table
|
Drugs & Compounds
for TIGD7 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for TIGD7
Search CenterWatch for drugs/clinical trials and news about TIGD7
|
Transcripts
for TIGD7 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for TIGD7 gene: NM_033208.3 Unigene Clusters for TIGD7: Tigger transposable element derived 7 Hs.161287 [show with all ESTs], Hs.744373 [show with all ESTs]Unigene Representative Sequences: NM_033208, AF2510509 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000396862(uc002cus.3) ENST00000573608 ENST00000574598 ENST00000572297
ENST00000570634 ENST00000573695 ENST00000576104 ENST00000571748 ENST00000268674(uc021tcc.1)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TIGD7
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TIGD7
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: TIGD7 (NM_033208) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for TIGD7 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TIGD7 |
Additional cDNA sequence: AF251050.2 7 DOTS entries: DT.97775880 DT.70104846 DT.75101401 DT.40195064 DT.413448 DT.120672492 DT.120672488 24/186 AceView cDNA sequences (see all 186): AI672612 BU732189 AI992371 CA416160 BQ941689 AI147238 N80183 AI151405 BQ881837 CA441502 AA808554 AI150784 D88827 BE350345 BQ069970 BC069635 BU187961 CR602060 BQ448146 AW675291 AI968375 AA421783 AA426297 AA922509
GeneLoc Exon Structure
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Expression
for TIGD7 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| TIGD7 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CCCTGCCGGA
About this image
See TIGD7 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for TIGD7
SOURCE GeneReport for Unigene clusters: Hs.161287 Hs.744373
UniProtKB/Swiss-Prot: TIGD7_HUMAN, Q6NT04Tissue specificity: Expressed in all tissues tested. Higher expression in testis and ovary
SABiosciences Custom PCR Arrays for TIGD7
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for TIGD7
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat TIGD7 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TIGD7 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TIGD7 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TIGD7 |
Orthologs
for TIGD7 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for TIGD7 gene from 1/6 species (see all 6) About this table
ENSEMBL Gene Tree for TIGD7 (if available)
TreeFam Gene Tree for TIGD7 (if available) |
Paralogs
for TIGD7 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for TIGD7 gene
- TIGD22 TIGD12 CENPB2 TIGD62 TIGD42 JRKL2 TIGD52 TIGD32
2 SIMAP similar genes for TIGD7 using alignment to 2 protein entries: TIGD7_HUMAN (see all proteins):TIGD2 JRKL
TIGD7 for paralogs About GeneDecksing
1 Pseudogenes.org Pseudogene for TIGD7
PGOHUM00000242029
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Genomic Variants
for TIGD7 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 16 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for TIGD7 (3348832 - 3355729 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for TIGD7: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing TIGD7 |
|
Disorders
/ Diseases
for TIGD7 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
 TIGD7 for disorders About MalaCards
TIGD7 for disorders About GeneDecksing
OMIM gene information: 612969
OMIM disorders: --
Export disorders for TIGD7 gene to outside databases
|
Publications
for TIGD7 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for TIGD7 gene integrated from 9 sources:
(articles sorted by number of sources associating them with TIGD7) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Isolation and characterization of a Jerky and JRK/JH8 like gene, tigger transposable element derived 7, TIGD7. (PubMed id 15487591)1, 2 Dou T....Mao Y. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1 Ota T.... Sugano S. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
|
External Searches for TIGD7 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing TIGD7 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing TIGD7 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing TIGD7 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for TIGD7 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for TIGD7 gene:
Search GeneIP for patents involving TIGD7
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for TIGD7 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for TIGD7 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for TIGD7 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for TIGD7 | | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for TIGD7 | | OriGene 3'-UTR Clone for TIGD7 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TIGD7 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TIGD7 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
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 | | | TIGD7 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TIGD7 |
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