TICAM2 Gene
protein-coding GIFtS: 55
GCID: GC05M114942
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|
toll-like receptor adaptor molecule 2
| |
Aliases
for TICAM2 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Toll-Like Receptor Adaptor Molecule 21 2 | | Cytoplasmic Adaptor2 | | TIRP1 2 3 5 | | NF-Kappa-B-Activating Protein 5022 | | TRAM1 2 3 5 | | TIR Domain-Containing Adapter Molecule 22 | | TICAM-21 2 3 | | Toll/Interleukin-1 Receptor (TIR) Domain-Containing Adapter Protein2 | | Putative NF-Kappa-B-Activating Protein 5022 3 | | TRIF-Related Adaptor Molecule2 | | Toll-Like Receptor Adaptor Protein 32 3 | | Toll/Interleukin-1 Receptor Domain-Containing Protein3 | | MyD88-42 3 | | TRIF-Related Adapter Molecule3 | | TIRAP32 3 | | |
Export aliases for TICAM2 gene to outside databasesPrevious GC identifers: GC00U917008 GC05M110096 |
Summaries
for TICAM2 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for TICAM2:
TIRP is a Toll/interleukin-1 receptor (IL1R; MIM 147810) (TIR) domain-containing adaptor protein involved in Tollreceptor signaling (see TLR4; MIM 603030).(supplied by OMIM, Apr 2004)
UniProtKB/Swiss-Prot: TCAM2_HUMAN, Q86XR7Function: Functions in LPS-TLR4 signaling to regulate the MYD88-independent pathway during the innate immune responseto LPS. Also involved in IL1-triggered NF-kappa-B activation, functioning upstream of IRAK1, IRAK2, TRAF6, and IKBKB.Physically bridges TLR4 and TICAM1 and functionally transmits LPS-TRL4 signal to TICAM1
Gene Wiki entry for TICAM2
|
Genomic Views
for TICAM2 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000005.9 NC_018916.1 NT_034772.6
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the TICAM2 gene promoter:
STAT1 HOXA3 AML1a GCNF AREB6 GCNF-1 FOXO4 ZID GCNF-2
Other transcription factors
Search SABiosciences Chromatin IP Primers for TICAM2
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TICAM2 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 5q23.1 Ensembl cytogenetic band: 5q22.3 HGNC cytogenetic band: 5q22.3TICAM2 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 5 GeneLoc Exon Structure GeneLoc location for GC05M114942: view genomic region
(about GC identifiers)
Start:
|
114,914,339 bp from pter |
End:
|
114,961,876 bp from pter |
Size:
|
47,538 bases |
Orientation:
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minus strand |
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Proteins
for TICAM2 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: TCAM2_HUMAN, Q86XR7 (See
protein sequence)Recommended Name: TIR domain-containing adapter molecule 2 Size: 235 amino acids; 26916 Da
Subunit: Homodimer. Interacts with TLR4, TICAM1, IRF3 and IRF7 in response to LPS. Interacts with IL1R1, IL1RAP, IRAK2,IRAK3 and TRAF6. Interacts with protein kinase-inactive mutants of IRAK1 and IRAK4
Subcellular location: Cytoplasm. Golgi apparatus. Cell membrane. Note=Localized to the plasma membrane as a result ofmyristoylation. Phosphorylation on Ser-16 leads to its depletion from the membrane
Secondary accessions: B3Y698Explore the universe of human proteins at neXtProt for TICAM2: NX_Q86XR7
Post-translational modifications:
Phosphorylated by PRKCE in response to LPS. Phosphorylation is essential for its function. It is depleted from themembrane upon phosphorylation1
Myristoylated. Required for membrane association which is critical for its ability to initiate efficient signaling1
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q86XR7
TICAM2 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_067681.1
ENSEMBL proteins: ENSP00000415139 ENSP00000386341 Reactome Protein details: Q86XR7
Human Recombinant Protein Products:
Gene Ontology (GO): 5 cellular component terms (GO ID links to tree view): About this table
TICAM2 for ontologies About GeneDecksing
TICAM2 Antibody Products:
Assay Products for TICAM2: |
Protein
Domains /
Families
for TICAM2 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
TICAM2 for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry Q86XR7ProtoNet protein and cluster: Q86XR7 UniProtKB/Swiss-Prot: TCAM2_HUMAN, Q86XR7Domain: The TIR domain mediates the interaction with TRAF6Similarity: Contains 1 TIR domain |
Function
for TICAM2 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: TCAM2_HUMAN, Q86XR7Function: Functions in LPS-TLR4 signaling to regulate the MYD88-independent pathway during the innate immune responseto LPS. Also involved in IL1-triggered NF-kappa-B activation, functioning upstream of IRAK1, IRAK2, TRAF6, and IKBKB.Physically bridges TLR4 and TICAM1 and functionally transmits LPS-TRL4 signal to TICAM1
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TICAM2 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TICAM2
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: TICAM2 (NM_021649) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for TICAM2 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TICAM2 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TICAM2 |
Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table
TICAM2 for ontologies About GeneDecksing
Animal Models:
Mouse knock-outs for TICAM2: Ticam2tm1Aki Ticam2tm1Btlr
1 MGI mutant phenotype (inferred from 2 alleles ) (MGI details for Ticam2):
TICAM2 for phenotypes About GeneDecksing
|
Pathways & Interactions
for TICAM2 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways - 5/7 super-pathways (see all 7) About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Auto ubiquitination of TRAF6 bound to the activated TLR complex | | | 2 | TRAF6 Mediated Induction of proinflammatory cytokines | | | 3 | Toll-like receptor signaling pathway | | | 4 | Immune response_TLR3 and TLR4 induce TICAM1-specific signaling pathway | | | 5 | Immune System | |
Pathway sources
See GeneCards unified pathways
Show all pathways
1 EMD Millipore Pathway for TICAM2
2  R&D Systems Pathways for TICAM2
1  GeneGo (Thomson Reuters) Pathway for TICAM2
2  BioSystems Pathways for TICAM2
5/14 
Reactome Pathways for TICAM2 (see all 14)
2 
Kegg Pathways (Kegg details for TICAM2):
TICAM2 for pathways About GeneDecksing
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for TICAM2
STRING Interaction
Network Preview (showing 5 interactants - click image to see 23)
5/27 Interacting proteins for TICAM2 (Q86XR73 ENSP000003863414) via UniProtKB, MINT, STRING, and/or I2D (see all 27)About this table
Gene Ontology (GO): 5/15 biological process terms (GO ID links to tree view) (see all 15): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0002224 | toll-like receptor signaling pathway |
-- | -- | | GO:0002755 | MyD88-dependent toll-like receptor signaling pathway |
-- | -- | | GO:0002756 | MyD88-independent toll-like receptor signaling pathway |
-- | -- | | GO:0006810 | transport |
-- | -- | | GO:0006954 | inflammatory response |
IEA | -- |
TICAM2 for ontologies About GeneDecksing
|
Drugs & Compounds
for TICAM2 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for TICAM2
Search CenterWatch for drugs/clinical trials and news about TICAM2 / TCAM2
|
Transcripts
for TICAM2 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for TICAM2 gene: NM_021649.6 Unigene Cluster for TICAM2: Toll-like receptor adaptor molecule 2 Hs.744008 [show with all ESTs]Unigene Representative Sequence: NM_1818363 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000427199(uc003krc.3) ENST00000513729 ENST00000408996(uc003kre.3 uc003krd.3)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TICAM2 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TICAM2
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: TICAM2 (NM_021649) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for TICAM2 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TICAM2 |
Additional cDNA sequence: AB002442.1 AB002444.1 AB091054.1 AB097022.1 AB109098.1 AB446491.1 AK027512.1 AK074962.1 AK304210.1 AY232653.1 AY304582.1 BC019349.2 BC107426.1 BC109265.2 BC109266.2 18 DOTS entries: DT.91706620 DT.317427 DT.102829506 DT.100682969 DT.100794712 DT.91756295 DT.407654 DT.120852761 DT.86847868 DT.120852749 DT.407653 DT.75199754 DT.92419987 DT.120852775 DT.120852782 DT.444446 DT.95134675 DT.95134689 24/366 AceView cDNA sequences (see all 366): BU684585 AA639647 CN479117 BQ639833 CD251250 AW514768 BM129556 AA677458 AA811528 AI304459 AI537661 CA394852 BM679315 AK075218 AI143515 CD679115 AI814089 AY304584 AY275836 CN481703 BE062250 AA287681 BM824561 BM129294
GeneLoc Exon Structure
|
Expression
for TICAM2 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| TICAM2 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GGCATATGTA
About this image
See TICAM2 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for TICAM2
SOURCE GeneReport for Unigene cluster: Hs.744008
UniProtKB/Swiss-Prot: TCAM2_HUMAN, Q86XR7Tissue specificity: Expressed in spleen, prostate, testis, uterus, small intestine, colon, peripheral blood leukocytes,heart, placenta, lung, liver, skeletal muscle, and pancreas
SABiosciences Expression via Pathway-Focused PCR Arrays including TICAM2:
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for TICAM2
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat TICAM2 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TICAM2 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TICAM2 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TICAM2 |
Orthologs
for TICAM2 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for TICAM2 gene from 5/21 species (see all 21) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
E1BQH3_CHICK6 |
Uncharacterized protein |
59(a) |
1 → many |
Z(71110462-71115876) |
lizard
(Anolis carolinensis) |
Reptilia |
-- |
-- |
69(a) |
1 → many |
GL343193.1(8321020-8326692) |
zebrafish
(Danio rerio) |
Actinopterygii |
tmed76 |
transmembrane emp24 protein transport domain conta... |
66(a) |
1 → many |
8(442391-447707) |
fruit fly
(Drosophila melanogaster) |
Insecta |
p24-16 |
p24-related-1 |
41(a) |
1 → many |
X(11745364-11746548) |
worm
(Caenorhabditis elegans) |
Secernentea |
F57B10.56 |
Protein F57B10.5 |
49(a) |
1 → many |
I(6562698-6563661) |
ENSEMBL Gene Tree for TICAM2 (if available)
TreeFam Gene Tree for TICAM2 (if available) |
Paralogs
for TICAM2 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for TICAM2 gene
- TMED52 TMED12 TMED7-TICAM22 TMED22 TMED32 TMED72
1 SIMAP similar gene for TICAM2 using alignment to 1 protein entry: TCAM2_HUMAN:TIRAP3
TICAM2 for paralogs About GeneDecksing
|
Genomic Variants
for TICAM2 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 5 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for TICAM2 (114914339 - 114961876 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 3 variations for TICAM2
3 CNVs: 93197 81015 93198 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing TICAM2 |
|
Disorders
/ Diseases
for TICAM2 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
TICAM2 for disorders About GeneDecksing
OMIM gene information: 608321
OMIM disorders: --
6  diseases for TICAM2: About MalaCardsprogressive multifocal leukoencephalopathy vaccinia pertussis lung cancer
prostatitis urinary tract infection
Human Genome Epidemiology (HuGE) Navigator: TICAM2 (3 documents)
Export disorders for TICAM2 gene to outside databases
|
Publications
for TICAM2 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for TICAM2 gene, integrated from 9 sources (see all 32):
(articles sorted by number of sources associating them with TICAM2) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- TIRP, a novel Toll/interleukin-1 receptor (TIR) domain-containing adapter protein involved in TIR signaling. (PubMed id 12721283)1, 2, 9 Bin L.H.... Shu H.B. (2003)
- Natural selection in the TLR-related genes in the course of primate evolution. (PubMed id 18810425)1, 2 Nakajima T....Kimura A. (2008)
- The myristoylation of TRIF-related adaptor molecule is essential for Toll-like receptor 4 signal transduction. (PubMed id 16603631)1, 2 Rowe D.C.... Golenbock D.T. (2006)
- Large-scale identification and characterization of human genes that activate NF-kappaB and MAPK signaling pathways. (PubMed id 12761501)1, 2 Matsuda A....Sugano S. (2003)
- TIR-containing adapter molecule (TICAM)-2, a bridging adapter recruiting to toll-like receptor 4 TICAM-1 that induces interferon- beta. (PubMed id 14519765)1, 2 Oshiumi H.... Seya T. (2003)
- LPS-TLR4 signaling to IRF-3/7 and NF-kappaB involves the toll adapters TRAM and TRIF. (PubMed id 14517278)1, 2 Fitzgerald K.A.... Golenbock D.T. (2003)
- TRAM is involved in IL-18 signaling and functions as a sorting adaptor for MyD88. (PubMed id 22685567)1 Ohnishi H....Kondo N. (2012)
- Mapping a dynamic innate immunity protein interaction network regulating type I interferon production. (PubMed id 21903422)1 Li S....Dorf M.E. (2011)
- Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1 Rose J.E....Uhl G.R. (2010)
- Viral inhibitory peptide of TLR4, a peptide derived f rom vaccinia protein A46, specifically inhibits TLR4 by directly targeting MyD8 8 adaptor-like and TRIF-related adaptor molecule. (PubMed id 20802145)1 Lysakova-Devine T....Bowie A.G. (2010)
|
External Searches for TICAM2 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing TICAM2 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing TICAM2 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing TICAM2 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for TICAM2 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for TICAM2 gene:
Search GeneIP for patents involving TICAM2
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for TICAM2 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | OriGene Antibodies for TICAM2 | | OriGene shRNA RFP for TICAM2 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for TICAM2 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for TICAM2 | | | OriGene Protein Over-expression Lysate for TICAM2 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for TICAM2 | | OriGene 3'-UTR Clone for TICAM2 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TICAM2 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TICAM2 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for TICAM2 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for TICAM2 | | OriGene Custom Protein Services for TICAM2 | | | OriGene Custom Immunoassay Development | | |
| |
 |
 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat TICAM2 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing TICAM2 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TICAM2 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TICAM2 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TICAM2 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TICAM2 |
| |
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| | | | Search Tocris compounds for TICAM2 |
| |  |  |  |  | | | | | | Recombinant Protein for TICAM2 |
|
 |
 |
 |
 | | | TICAM2 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TICAM2 |
|  |  |  | | | | ThermoFisher Antibodies for TICAM2 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TICAM2 |
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