TICAM1 Gene
protein-coding GIFtS: 55
GCID: GC19M004815
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|
toll-like receptor adaptor molecule 1
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Aliases
for TICAM1 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Toll-Like Receptor Adaptor Molecule 11 2 | | MyD88-32 3 | | TRIF1 2 3 5 | | TIR Domain-Containing Adapter Protein Inducing IFN-Beta2 3 | | PRVTIRB1 2 3 | | MGC353341 | | TICAM-11 2 3 | | IIAE62 | | Proline-Rich, Vinculin And TIR Domain-Containing Protein B2 3 | | TIR Domain Containing Adaptor Inducing Interferon-Beta2 | | Putative NF-Kappa-B-Activating Protein 502H2 3 | | TIR Domain-Containing Adapter Molecule 12 | | Toll-Interleukin-1 Receptor Domain-Containing Adapter Protein InducingInterferon Beta2 3 | | |
Export aliases for TICAM1 gene to outside databasesPrevious GC identifers: GC19M004767 GC19M004577 |
Summaries
for TICAM1 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for TICAM1:
This gene encodes an adaptor protein containing a Toll/interleukin-1 receptor (TIR) homology domain, which is anintracellular signaling domain that mediates protein-protein interactions between the Toll-like receptors (TLRs) andsignal-transduction components. This protein is involved in native immunity against invading pathogens. Itspecifically interacts with toll-like receptor 3, but not with other TLRs, and this association mediates dsRNAinduction of interferon-beta through activation of nuclear factor kappa-B, during an antiviral immune response.(provided by RefSeq, Jan 2012)
UniProtKB/Swiss-Prot: TCAM1_HUMAN, Q8IUC6Function: Involved in innate immunity against invading pathogens. Adapter used by TLR3 and TLR4 (through TICAM2) tomediate NF-kappa-B and interferon-regulatory factor (IRF) activation, and to induce apoptosis. Ligand binding to thesereceptors results in TRIF recruitment through its TIR domain. Distinct protein-interaction motifs allow recruitment ofthe effector proteins TBK1, TRAF6 and RIPK1, which in turn, lead to the activation of transcription factors IRF3 andIRF7, NF-kappa-B and FADD respectively
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Genomic Views
for TICAM1 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000019.9 NC_018930.1 NT_011255.14
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the TICAM1 gene promoter:
CRE-BP1 Tal-1 ATF-2 NF-kappaB NF-kappaB1 E47
Other transcription factors
Search SABiosciences Chromatin IP Primers for TICAM1
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TICAM1 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 19p13.3 Ensembl cytogenetic band: 19p13.3 HGNC cytogenetic band: 19p13.3TICAM1 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 19 GeneLoc Exon Structure GeneLoc location for GC19M004815: view genomic region
(about GC identifiers)
Start:
|
4,815,938 bp from pter |
End:
|
4,831,737 bp from pter |
Size:
|
15,800 bases |
Orientation:
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minus strand |
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Proteins
for TICAM1 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: TCAM1_HUMAN, Q8IUC6 (See
protein sequence)Recommended Name: TIR domain-containing adapter molecule 1 Size: 712 amino acids; 76422 Da
Subunit: Homodimer (Probable). Interacts with the TIR domain of TLR3. Interacts with AZI2, TBK1, IRF3 and IRF7.Interacts with TICAM2 in TLR4 recruitment. Interaction with PIAS4 inhibits the TICAM1-induced NF-kappa-B, IRF andIFNB1 activation. Interacts with IKBKB and IKBKE. Interaction with SARM1 blocks TICAM1-dependent transcription factoractivation. Interacts with TRAF3 (By similarity). Interacts with TRAF6. Interacts with TRAFD1 (By similarity)
Sequence caution: Sequence=AAO85488.1; Type=Frameshift; Positions=141, 148, 161;
1 PDB 3D structure from  and Proteopedia  for TICAM1:3RC4 (3D)
Secondary accessions: B3Y691 O75532 Q86XP8 Q96GA0Explore the universe of human proteins at neXtProt for TICAM1: NX_Q8IUC6
Post-translational modifications:
Phosphorylated by TBK11
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q8IUC6
TICAM1 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_891549.1
ENSEMBL proteins: ENSP00000248244 Reactome Protein details: Q8IUC6
Human Recombinant Protein Products:
Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view): About this table
TICAM1 for ontologies About GeneDecksing
TICAM1 Antibody Products:
Assay Products for TICAM1: |
Protein
Domains /
Families
for TICAM1 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
TICAM1 for domains About GeneDecksing
2 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q8IUC6ProtoNet protein and cluster: Q8IUC6 UniProtKB/Swiss-Prot: TCAM1_HUMAN, Q8IUC6Domain: The N-terminal region is essential for activation of the IFNB promoter activitySimilarity: Contains 1 TIR domain |
Function
for TICAM1 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: TCAM1_HUMAN, Q8IUC6Function: Involved in innate immunity against invading pathogens. Adapter used by TLR3 and TLR4 (through TICAM2) tomediate NF-kappa-B and interferon-regulatory factor (IRF) activation, and to induce apoptosis. Ligand binding to thesereceptors results in TRIF recruitment through its TIR domain. Distinct protein-interaction motifs allow recruitment ofthe effector proteins TBK1, TRAF6 and RIPK1, which in turn, lead to the activation of transcription factors IRF3 andIRF7, NF-kappa-B and FADD respectively
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TICAM1 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TICAM1
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: TICAM1 (NM_182919) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for TICAM1 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TICAM1 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TICAM1 |
Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table
TICAM1 for ontologies About GeneDecksing
Animal Models:
Mouse knock-outs for TICAM1: Ticam1tm1Aki Ticam1tm1Tsse
13 MGI mutant phenotypes (inferred from 3 alleles ) (MGI details for Ticam1):
TICAM1 for phenotypes About GeneDecksing
|
Pathways & Interactions
for TICAM1 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways - 5/9 super-pathways (see all 9) About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Auto ubiquitination of TRAF6 bound to the activated TLR complex | | | 2 | TRAF6 Mediated Induction of proinflammatory cytokines | | | 3 | Toll-like receptor signaling pathway | | | 4 | Immune response_TLR3 and TLR4 induce TICAM1-specific signaling pathway | | | 5 | Immune System | |
Pathway sources
See GeneCards unified pathways
Show all pathways
1 EMD Millipore Pathway for TICAM1
2  R&D Systems Pathways for TICAM1
1 
Cell Signaling Technology (CST) Pathway for TICAM1
1  GeneGo (Thomson Reuters) Pathway for TICAM1
1  BioSystems Pathway for TICAM1
5/14 
Reactome Pathways for TICAM1 (see all 14)
5 
Kegg Pathways (Kegg details for TICAM1):
TICAM1 for pathways About GeneDecksing
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for TICAM1
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/57 Interacting proteins for TICAM1 (Q8IUC62, 3 ENSP000002482444) via UniProtKB, MINT, STRING, and/or I2D (see all 57)About this table
Gene Ontology (GO): 5/32 biological process terms (GO ID links to tree view) (see all 32): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0002224 | toll-like receptor signaling pathway |
-- | -- | | GO:0002281 | macrophage activation involved in immune response |
IEA | -- | | GO:0002755 | MyD88-dependent toll-like receptor signaling pathway |
-- | -- | | GO:0002756 | MyD88-independent toll-like receptor signaling pathway |
TAS | -- | | GO:0006915 | apoptotic process |
IEA | -- |
TICAM1 for ontologies About GeneDecksing
|
Drugs & Compounds
for TICAM1 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
TICAM1 for compounds About GeneDecksing
 Browse Tocris compounds for TICAM1
3 Novoseek chemical compound relationships for TICAM1 gene About this table
Search CenterWatch for drugs/clinical trials and news about TICAM1 / TCAM1
|
Transcripts
for TICAM1 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for TICAM1 gene (2 alternative transcripts): NM_182919.3 NM_014261.1 Unigene Cluster for TICAM1: Toll-like receptor adaptor molecule 1 Hs.29344 [show with all ESTs]Unigene Representative Sequence: BC0353311 Ensembl transcript including schematic representation, and UCSC links where relevant: ENST00000248244(uc002mbi.3)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TICAM1 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TICAM1
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: TICAM1 (NM_182919) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for TICAM1 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TICAM1 |
Additional cDNA sequence: AB086380.1 AB093555.1 AB097023.1 AB446484.1 AF070530.1 BC009860.2 BC035331.1 BC136556.1 BC136557.1 4 DOTS entries: DT.213492 DT.95107436 DT.95262570 DT.95363392 24/106 AceView cDNA sequences (see all 106): BM550597 BU173884 AF070530 BQ684287 BQ772589 AB093555 CD365233 CA443266 CA308725 AA926989 CF242882 CD367514 CR592986 BM763771 NM_182919 AW138109 AB086380 AB097023 AA357024 BE513301 BG753470 BE545285 AA366190 BE747097
GeneLoc Exon Structure
|
Expression
for TICAM1 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| TICAM1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TGGAACCAGA
About this image
See TICAM1 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for TICAM1
SOURCE GeneReport for Unigene cluster: Hs.29344
UniProtKB/Swiss-Prot: TCAM1_HUMAN, Q8IUC6Tissue specificity: Ubiquitously expressed but with higher levels in liver
SABiosciences Expression via Pathway-Focused PCR Arrays including TICAM1 (see all 6): | Innate & Adaptive Immune Responses in human mouse rat | | Antiviral Response in human mouse rat | | Toll-Like Receptor Signaling Pathway in human mouse rat | | Type I Interferon Response in human mouse rat | | NFKB Signaling Pathway in human mouse rat |
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for TICAM1
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat TICAM1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TICAM1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TICAM1 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TICAM1 |
Orthologs
for TICAM1 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for TICAM1 gene from 4/9 species (see all 9) About this table
ENSEMBL Gene Tree for TICAM1 (if available)
TreeFam Gene Tree for TICAM1 (if available) |
Paralogs
for TICAM1 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for TICAM1 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 19 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for TICAM1 (4815938 - 4831737 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for TICAM1: --
Human Gene Mutation Database (HGMD): TICAM1
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing TICAM1 |
|
Disorders
/ Diseases
for TICAM1 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
TICAM1 for disorders About GeneDecksing
OMIM gene information: 607601
OMIM disorders: --
UniProtKB/Swiss-Prot: TCAM1_HUMAN, Q8IUC6
Defects in TICAM1 are the cause of susceptibility to herpes simplex encephalitis 4 (HSE4) [MIM:614850]. A rarecomplication of human herpesvirus 1 (HHV-1) infection, occurring in only a small minority of HHV-1 infectedindividuals. HSE is characterized by hemorrhagic necrosis of parts of the temporal and frontal lobes. Onset is overseveral days and involves fever, headache, seizures, stupor, and often coma, frequently with a fatal outcome
20/29  diseases for TICAM1 (see all 29): About MalaCardsdengue hemorrhagic fever herpes simplex encephalitis hemorrhagic fever herpes simplex
chronic lymphocytic leukemia trypanosomiasis lymphocytic leukemia cellulitis
kaposi's sarcoma hepatitis a encephalitis kawasaki disease
chagas disease rheumatoid arthritis synovitis hepatitis c
hepatitis b hepatitis sarcoma pertussis
3 Novoseek disease relationships for TICAM1 gene About this table
Human Genome Epidemiology (HuGE) Navigator: TICAM1 (11 documents)
Export disorders for TICAM1 gene to outside databases
|
Publications
for TICAM1 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for TICAM1 gene, integrated from 9 sources (see all 145):
(articles sorted by number of sources associating them with TICAM1) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- A novel Toll/IL-1 receptor domain-containing adapter that preferentially activates the IFN-beta promoter in the Toll-like receptor signaling. (PubMed id 12471095)1, 2, 3, 9 Yamamoto M....Akira S. (2002)
- TICAM-1, an adapter molecule that participates in Toll-like receptor 3 mediated interferon-beta induction. (PubMed id 12539043)1, 2, 3 Oshiumi H.... Seya T. (2003)
- Toll/IL-1 receptor domain-containing adaptor inducing IFN-beta (TRIF) associates with TNF receptor-associated factor 6 and TANK-binding kinase 1, and activates two distinct transcription factors, NF-kappa B and IFN-regulatory factor-3, in the Toll-like receptor signaling. (PubMed id 14530355)1, 2, 9 Sato S....Akira S. (2003)
- Toll-like receptor 3-mediated activation of NF-kappaB and IRF3 diverges at Toll-IL-1 receptor domain-containing adapter inducing IFN- beta. (PubMed id 14982987)1, 2, 9 Jiang Z.... Li X. (2004)
- Mechanisms of the TRIF-induced interferon-stimulated response element and NF-kappaB activation and apoptosis pathways. (PubMed id 14739303)1, 2, 9 Han K.J.... Shu H.-B. (2004)
- The human adaptor SARM negatively regulates adaptor protein TRIF- dependent Toll-like receptor signaling. (PubMed id 16964262)1, 2, 9 Carty M....Bowie A.G. (2006)
- NF-kappaB-activating kinase-associated protein 1 participates in TLR3/Toll-IL-1 homology domain-containing adapter molecule-1-mediated IFN regulatory factor 3 activation. (PubMed id 15611223)1, 2, 9 Sasai M....Seya T. (2005)
- Herpes simplex encephalitis in children with autosoma l recessive and dominant TRIF deficiency. (PubMed id 22105173)1, 2 Sancho-Shimizu V....Casanova J.L. (2011)
- Natural selection in the TLR-related genes in the course of primate evolution. (PubMed id 18810425)1, 2 Nakajima T....Kimura A. (2008)
- PIASy represses TRIF-induced ISRE and NF-kappaB activation but not apoptosis. (PubMed id 15251447)1, 2 Zhang J....Shu H.B. (2004)
|
External Searches for TICAM1 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing TICAM1 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing TICAM1 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing TICAM1 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for TICAM1 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for TICAM1 gene:
Search GeneIP for patents involving TICAM1
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for TICAM1 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | OriGene Antibodies for TICAM1 | | Browse OriGene shRNA RFPs | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for TICAM1 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for TICAM1 | | | OriGene Protein Over-expression Lysate for TICAM1 | | Browse OriGene Fluorogenic Cell Assay Kits | | | Browse OriGene siRNAs | | OriGene 3'-UTR Clone for TICAM1 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TICAM1 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TICAM1 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for TICAM1 | | OriGene Custom Protein Services for TICAM1 | | | OriGene Custom Immunoassay Development | | |
| |
 |
 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat TICAM1 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing TICAM1 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TICAM1 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TICAM1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TICAM1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TICAM1 |
| |
 |  |  |  | |
| | Antibodies & Assays for TICAM1 |
| | | | Search Tocris compounds for TICAM1 |
| |  |  |  |  | | | | |
 |
 |
 |
 | | | TICAM1 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TICAM1 |
|  |  |  | | | | ThermoFisher Antibodies for TICAM1 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TICAM1 |
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