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Aliases for THUMPD3 Gene

Aliases for THUMPD3 Gene

  • THUMP Domain Containing 3 2 3

External Ids for THUMPD3 Gene

Previous GeneCards Identifiers for THUMPD3 Gene

  • GC03P009380
  • GC03P009381
  • GC03P009341
  • GC03P009405
  • GC03P009406
  • GC03P009407
  • GC03P009408
  • GC03P009409
  • GC03P009410
  • GC03P009412

Summaries for THUMPD3 Gene

GeneCards Summary for THUMPD3 Gene

THUMPD3 (THUMP Domain Containing 3) is a Protein Coding gene. GO annotations related to this gene include RNA binding and methyltransferase activity. An important paralog of this gene is THUMPD2.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for THUMPD3 Gene

Genomics for THUMPD3 Gene

Regulatory Elements for THUMPD3 Gene

Genomic Location for THUMPD3 Gene

Start:
9,362,842 bp from pter
End:
9,386,791 bp from pter
Size:
23,950 bases
Orientation:
Plus strand

Genomic View for THUMPD3 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for THUMPD3 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for THUMPD3 Gene

Proteins for THUMPD3 Gene

  • Protein details for THUMPD3 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9BV44-THUM3_HUMAN
    Recommended name:
    THUMP domain-containing protein 3
    Protein Accession:
    Q9BV44
    Secondary Accessions:
    • Q9H8V6
    • Q9NVC1
    • Q9UFS3

    Protein attributes for THUMPD3 Gene

    Size:
    507 amino acids
    Molecular mass:
    57003 Da
    Quaternary structure:
    No Data Available

neXtProt entry for THUMPD3 Gene

Proteomics data for THUMPD3 Gene at MOPED

Post-translational modifications for THUMPD3 Gene

  • Ubiquitination at Lys369, Lys376, Lys411, and Lys449
  • Modification sites at PhosphoSitePlus

Other Protein References for THUMPD3 Gene

No data available for DME Specific Peptides for THUMPD3 Gene

Domains for THUMPD3 Gene

Protein Domains for THUMPD3 Gene

Suggested Antigen Peptide Sequences for THUMPD3 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q9BV44

UniProtKB/Swiss-Prot:

THUM3_HUMAN :
  • Q9BV44
Domain:
  • Contains 1 THUMP domain.
Family:
  • Belongs to the methyltransferase superfamily.
genes like me logo Genes that share domains with THUMPD3: view

No data available for Gene Families for THUMPD3 Gene

Function for THUMPD3 Gene

Gene Ontology (GO) - Molecular Function for THUMPD3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003723 RNA binding IEA --
GO:0008168 methyltransferase activity IEA --
genes like me logo Genes that share ontologies with THUMPD3: view

Animal Model Products

CRISPR Products

miRNA for THUMPD3 Gene

miRTarBase miRNAs that target THUMPD3

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for THUMPD3

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for THUMPD3 Gene

Localization for THUMPD3 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for THUMPD3 Gene COMPARTMENTS Subcellular localization image for THUMPD3 gene
Compartment Confidence
cytosol 2
nucleus 2
mitochondrion 1

Gene Ontology (GO) - Cellular Components for THUMPD3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005730 nucleolus IDA --
GO:0005737 cytoplasm IDA --
genes like me logo Genes that share ontologies with THUMPD3: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for THUMPD3 Gene

Pathways for THUMPD3 Gene

SuperPathways for THUMPD3 Gene

No Data Available

Gene Ontology (GO) - Biological Process for THUMPD3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0032259 methylation IEA --
genes like me logo Genes that share ontologies with THUMPD3: view

No data available for Pathways by source for THUMPD3 Gene

Transcripts for THUMPD3 Gene

Unigene Clusters for THUMPD3 Gene

THUMP domain containing 3:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for THUMPD3

Primer Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for THUMPD3 Gene

ExUns: 1a · 1b · 1c · 1d · 1e · 1f ^ 2a · 2b ^ 3 ^ 4a · 4b ^ 5a · 5b ^ 6a · 6b ^ 7a · 7b · 7c ^ 8 ^ 9 ^ 10a · 10b ^ 11a · 11b ^ 12a · 12b ^
SP1: - - -
SP2: - - - - -
SP3:
SP4: - - - - - -
SP5: - - - -
SP6: - - - -
SP7: - - -
SP8:
SP9: - - - -
SP10: - - - - -
SP11: - -
SP12:

ExUns: 13
SP1:
SP2:
SP3:
SP4:
SP5:
SP6:
SP7:
SP8:
SP9:
SP10:
SP11:
SP12:

Relevant External Links for THUMPD3 Gene

GeneLoc Exon Structure for
THUMPD3
ECgene alternative splicing isoforms for
THUMPD3

Expression for THUMPD3 Gene

mRNA expression in normal human tissues for THUMPD3 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for THUMPD3 Gene

SOURCE GeneReport for Unigene cluster for THUMPD3 Gene Hs.443081

genes like me logo Genes that share expressions with THUMPD3: view

In Situ Assay Products

No data available for mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for THUMPD3 Gene

Orthologs for THUMPD3 Gene

This gene was present in the common ancestor of animals.

Orthologs for THUMPD3 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia THUMPD3 35
  • 99.3 (n)
  • 99.16 (a)
THUMPD3 36
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia THUMPD3 35
  • 88.51 (n)
  • 83.97 (a)
THUMPD3 36
  • 83 (a)
OneToOne
dog
(Canis familiaris)
Mammalia -- 36
  • 82 (a)
OneToMany
THUMPD3 35
  • 90.04 (n)
  • 86.65 (a)
THUMPD3 36
  • 86 (a)
OneToMany
mouse
(Mus musculus)
Mammalia Thumpd3 35
  • 84.2 (n)
  • 80.68 (a)
Thumpd3 16
Thumpd3 36
  • 80 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia -- 36
  • 57 (a)
OneToMany
-- 36
  • 69 (a)
OneToMany
platypus
(Ornithorhynchus anatinus)
Mammalia THUMPD3 36
  • 63 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Thumpd3 35
  • 83.5 (n)
  • 80.52 (a)
chicken
(Gallus gallus)
Aves THUMPD3 35
  • 69.41 (n)
  • 69.27 (a)
THUMPD3 36
  • 63 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia THUMPD3 36
  • 60 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia thumpd3 35
  • 63.3 (n)
  • 62.66 (a)
zebrafish
(Danio rerio)
Actinopterygii thumpd3 35
  • 60.89 (n)
  • 60.96 (a)
thumpd3 36
  • 58 (a)
OneToOne
worm
(Caenorhabditis elegans)
Secernentea CELE_M04B2.2 35
  • 49.78 (n)
  • 41.69 (a)
M04B2.2 36
  • 39 (a)
OneToMany
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 44 (a)
OneToMany
Species with no ortholog for THUMPD3:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for THUMPD3 Gene

ENSEMBL:
Gene Tree for THUMPD3 (if available)
TreeFam:
Gene Tree for THUMPD3 (if available)

Paralogs for THUMPD3 Gene

Paralogs for THUMPD3 Gene

Pseudogenes.org Pseudogenes for THUMPD3 Gene

genes like me logo Genes that share paralogs with THUMPD3: view

Variants for THUMPD3 Gene

Sequence variations from dbSNP and Humsavar for THUMPD3 Gene

SNP ID Clin Chr 03 pos Sequence Context AA Info Type MAF
rs1046788 -- 9,384,260(+) CTACG(C/G)GAGAT synonymous-codon, reference
rs1047824 -- 9,385,781(-) TTTTT(C/T)TCTTG utr-variant-3-prime
rs1047825 -- 9,385,779(-) TTTCT(C/T)TTGGC utr-variant-3-prime
rs1054975 -- 9,365,152(+) GAAAG(C/T)GACCT synonymous-codon, reference
rs1129170 -- 9,384,227(+) AAGAA(A/G)AGAAA synonymous-codon, reference

Relevant External Links for THUMPD3 Gene

HapMap Linkage Disequilibrium report
THUMPD3

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for THUMPD3 Gene

Disorders for THUMPD3 Gene

No disorders were found for THUMPD3 Gene.

No data available for UniProtKB/Swiss-Prot for THUMPD3 Gene

Publications for THUMPD3 Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  4. A protein interaction framework for human mRNA degradation. (PMID: 15231747) Lehner B. … Sanderson C.M. (Genome Res. 2004) 3
  5. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3

Products for THUMPD3 Gene

  • antibodies-online proteins for THUMPD3
  • antibodies-online antibodies for THUMPD3
  • antibodies-online kits for THUMPD3

Sources for THUMPD3 Gene

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