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THRSP Gene

protein-coding   GIFtS: 52
GCID: GC11P077776

Thyroid Hormone Responsive

(Previous names: thyroid hormone responsive SPOT14 (rat) homolog, lipogenic...)
(Previous symbol: LPGP1)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Thyroid Hormone Responsive1 2     Thyroid Hormone Responsive SPOT14 (Rat) Homolog1
LPGP11 2     Lpgp2
Lipogenic Protein 11 2     THRP2
Spot 14 Protein2 3     SPOT14 Homolog2
S142 3     Thyroid Hormone Responsive (SPOT14 Homolog, Rat)2
SPOT142 3     Thyroid Hormone Responsive SPOT142
SPOT14 Homolog (Rat)1     Thyroid Hormone-Inducible Hepatic Protein2

External Ids:    HGNC: 118001   Entrez Gene: 70692   Ensembl: ENSG000001513657   OMIM: 6019265   UniProtKB: Q927483   

Export aliases for THRSP gene to outside databases

Previous GC identifers: GC11P080101 GC11M079313 GC11P077997 GC11P077501 GC11P077452 GC11P074076


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for THRSP Gene:
The protein encoded by this gene is similar to the gene product of S14, a rat gene whose expression is limited to
liver and adipose tissue and is controlled by nutritional and hormonal factors. This gene has been shown to be
expressed in liver and adipocytes, particularly in lipomatous modules. It is also found to be expressed in
lipogenic breast cancers, which suggests a role in controlling tumor lipid metabolism. (provided by RefSeq, Jul
2008)

GeneCards Summary for THRSP Gene:
THRSP (thyroid hormone responsive) is a protein-coding gene. Diseases associated with THRSP include allan-herndon-dudley syndrome, and euthyroid sick syndrome. GO annotations related to this gene include protein homodimerization activity. An important paralog of this gene is MID1IP1.

UniProtKB/Swiss-Prot: THRSP_HUMAN, Q92748
Function: Plays a role in the regulation of lipogenesis, especially in lactating mammary gland. Important for the
biosynthesis of triglycerides with medium-length fatty acid chains. May modulate lipogenesis by interacting with
MID1IP1 and preventing its interaction with ACACA (By similarity). May function as transcriptional coactivator.
May modulate the transcription factor activity of THRB

Gene Wiki entry for THRSP Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000011.10  NC_018922.2  NT_167190.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the THRSP gene promoter:
         NF-1/L   NF-1   AP-1   ATF-2   E47   PPAR-gamma1   PPAR-gamma2   c-Jun   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidTHRSP promoter sequence
   Search Chromatin IP Primers for THRSP

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat THRSP


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 11q14.1   Ensembl cytogenetic band:  11q14.1   HGNC cytogenetic band: 11q14.1

THRSP Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
THRSP gene location

GeneLoc information about chromosome 11         GeneLoc Exon Structure

GeneLoc location for GC11P077776:  view genomic region     (about GC identifiers)

Start:
77,774,907 bp from pter      End:
77,779,403 bp from pter
Size:
4,497 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: THRSP_HUMAN, Q92748 (See protein sequence)
Recommended Name: Thyroid hormone-inducible hepatic protein  
Size: 146 amino acids; 16561 Da
Subunit: Homodimer. Heterodimer with MID1IP1 (By similarity). Interacts with THRB and PLAGL1
Secondary accessions: B2R4W7

Explore the universe of human proteins at neXtProt for THRSP: NX_Q92748

Explore proteomics data for THRSP at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See THRSP Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_003242.1  
    ENSEMBL proteins: 
     ENSP00000281030  

    THRSP Human Recombinant Protein Products:

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    1 InterPro protein domain:
     IPR009786 Spot_14

    Graphical View of Domain Structure for InterPro Entry Q92748

    ProtoNet protein and cluster: Q92748

    1 Blocks protein domain: IPB009786 Thyroid hormone-inducible hepatic Spot 14

    UniProtKB/Swiss-Prot: THRSP_HUMAN, Q92748
    Similarity: Belongs to the SPOT14 family


    THRSP for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: THRSP_HUMAN, Q92748
    Function: Plays a role in the regulation of lipogenesis, especially in lactating mammary gland. Important for the
    biosynthesis of triglycerides with medium-length fatty acid chains. May modulate lipogenesis by interacting with
    MID1IP1 and preventing its interaction with ACACA (By similarity). May function as transcriptional coactivator.
    May modulate the transcription factor activity of THRB

         Genatlas biochemistry entry for THRSP:
    thyroid hormone responsive spot 14,17kDa,rat homog,involved in lipogenesis in liver,mammary and adipose
    tissues,amplified in breast tumors with poor prognosis

         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding ----
    GO:0042803protein homodimerization activity IEA--
         
    THRSP for ontologies           About GeneDecksing


    Phenotypes:
         3 GenomeRNAi human phenotypes for THRSP:
     Decreased influenza A virus in  Increased gamma-H2AX phosphory  Synthetic lethal with Ras 

         3 MGI mutant phenotypes (inferred from 1 allele(MGI details for Thrsp):
     endocrine/exocrine gland  homeostasis/metabolism  integument 

    THRSP for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-out Thrsptm1Cnm for THRSP

       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for THRSP
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for THRSP

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for THRSP
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for THRSP

    miRNA
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    Block miRNA regulation of human, mouse, rat THRSP using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate THRSP (see all 12):
    hsa-miR-98 hsa-miR-1294 hsa-let-7d hsa-let-7c hsa-let-7i hsa-let-7e hsa-let-7g hsa-miR-141*
    SwitchGear 3'UTR luciferase reporter plasmidTHRSP 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat THRSP

    Gene Editing
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    Sino Biological Human cDNA Clone for THRSP
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for THRSP
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat THRSP

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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for THRSP


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    THRSP_HUMAN, Q92748: Nucleus. Cytoplasm
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus5
    cytosol4
    mitochondrion3
    golgi apparatus1
    peroxisome1
    plasma membrane1

    Gene Ontology (GO): 3 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA--
    GO:0005730NOT nucleolus IDA--
    GO:0005829cytosol ISS--

    THRSP for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Pathway & Disease-focused RT2 Profiler PCR Array including THRSP: 
              Hepatotoxicity in human mouse rat

    Interactions:

        Search GeneGlobe Interaction Network for THRSP

    STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

    1 Interacting protein for THRSP (ENSP000002810304) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    MID1IP1ENSP000003387064STRING: ENSP00000338706
    About this table

    Gene Ontology (GO): 5 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006351transcription, DNA-templated IEA--
    GO:0006355regulation of transcription, DNA-templated IEA--
    GO:0006629lipid metabolic process IEA--
    GO:0010866regulation of triglyceride biosynthetic process IEA--
    GO:0046890regulation of lipid biosynthetic process ISS--

    THRSP for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for THRSP

    8 Novoseek inferred chemical compound relationships for THRSP gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    fatty acid 52.4 19 19116881 (3), 12917410 (2), 10551830 (2), 1734874 (2) (see all 10)
    thyroxine 46.6 2 18647617 (1)
    triiodothyronine 40.4 6 9027365 (3), 12855010 (2)
    sterol 40.1 2 12917410 (1), 16300755 (1)
    glucose 27.1 15 8895333 (5), 11485565 (2), 8869748 (1), 12855010 (1) (see all 7)
    lipid 25.4 2 9027365 (1), 16809441 (1)
    pyruvate 16.9 2 11485565 (1), 9240934 (1)
    steroid 0 2 16552628 (2)



    THRSP for compounds           About GeneDecksing



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for THRSP gene: 
    NM_003251.3  

    Unigene Cluster for THRSP:

    Thyroid hormone responsive
    Hs.591969  [show with all ESTs]
    Unigene Representative Sequence: BC031989
    1 Ensembl transcript including schematic representation, and UCSC links where relevant:
    ENST00000281030(uc001oyx.3)
    miRNA
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    Selected qRT-PCR Assays for microRNAs that regulate THRSP (see all 12):
    hsa-miR-98 hsa-miR-1294 hsa-let-7d hsa-let-7c hsa-let-7i hsa-let-7e hsa-let-7g hsa-miR-141*
    SwitchGear 3'UTR luciferase reporter plasmidTHRSP 3' UTR sequence
    Inhib. RNA
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    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: THRSP (NM_003251)
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    Primer
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    OriGene qSTAR qPCR primer pairs in human, mouse for THRSP
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat THRSP
      QuantiTect SYBR Green Assays in human, mouse, rat THRSP
      QuantiFast Probe-based Assays in human, mouse, rat THRSP

    Additional mRNA sequence: 

    AK311975.1 BC031989.1 

    5 DOTS entries:

    DT.100703008  DT.428135  DT.95171696  DT.100779702  DT.100844445 

    Selected AceView cDNA sequences (see all 60):

    BG742057 CB139123 BG698070 NM_003251 BG741880 AI631972 CA407233 BG741308 
    AI927972 BG740485 BG696418 CB268329 BG743363 BG743579 AI215778 CB137802 
    BG675356 CB163960 AI654817 AI480357 BG675284 AW950269 BG696058 AV661846 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    THRSP expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TGAGGGCTAT
    THRSP Expression
    About this image


    THRSP expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 7) fully expand
     
     Neurons
             Mature Horizontal Cells Inner Nuclear Layer
     
     Eye (Sensory Organs)    fully expand to see all 3 entries
             Mature Horizontal Cells Inner Nuclear Layer
     
     Brain (Nervous System)    fully expand to see all 3 entries
             Cerebral Cortex
     
     Adipose (Muscoskeletal System)    fully expand to see all 2 entries
             Body Subcutaneous White Adipose
     
     Neural Tube (Nervous System)    fully expand to see all 2 entries
             Telencephalon
    THRSP Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    THRSP Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.591969

    UniProtKB/Swiss-Prot: THRSP_HUMAN, Q92748
    Tissue specificity: Mainly expressed in tissues that synthesize triglycerides

        Pathway & Disease-focused RT2 Profiler PCR Array including THRSP: 
              Hepatotoxicity in human mouse rat

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for THRSP

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for THRSP gene from Selected species (see all 9)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Thrsp1 , 5 thyroid hormone responsive SPOT14 homolog (Rattus)5
    thyroid hormone responsive1
    84.37(n)1
    85.52(a)1
      7 (53.49 cM)5
    218351  NM_009381.21  NP_033407.11 
     974129385 
    chicken
    (Gallus gallus)
    Aves THRSPB6
    THRSP6
    (see all 3)
    Gallus gallus thyroid hormone responsive spot 14 b...
    Thyroid hormone responsive spot 14 beta 1; Unchara...
    (see all 3)
    29(a)
    29(a)
    (see all 3)
    1 ↔ many
    1 ↔ many
    (see all 3)
    1(192070045-192070743) ENSGALG00000028911
    1(192066183-192066590) ENSGALG00000027901
    lizard
    (Anolis carolinensis)
    Reptilia --
    --
    Uncharacterized protein
    40(a)
    36(a)
    1 ↔ many
    1 ↔ many
    GL343337.1(573573-573953)
    GL343337.1(552528-552941)
    zebrafish
    (Danio rerio)
    Actinopterygii THRSP6
    thyroid hormone responsive
    34(a)
    1 ↔ 1
    15(9582648-9583121) ENSDARG00000089241


    ENSEMBL Gene Tree for THRSP (if available)
    TreeFam Gene Tree for THRSP (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for THRSP gene
    MID1IP12  
    1 SIMAP similar gene for THRSP using alignment to 1 protein entry:     THRSP_HUMAN:
    MID1IP1

    THRSP for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for THRSP:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv520740CNV Gain19592680

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing THRSP
    DNA2.0 Custom Variant and Variant Library Synthesis for THRSP

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 601926    OMIM disorders: --

    11 diseases for THRSP:    
    About MalaCards
    allan-herndon-dudley syndrome    euthyroid sick syndrome    intrahepatic cholangiocarcinoma    cholangiocarcinoma
    thyroiditis    liposarcoma    breast cancer    hepatitis
    hypothyroidism    obesity    cerebritis

    1 disease from the University of Copenhagen DISEASES database for THRSP:
    Hypothyroidism

    THRSP for disorders           About GeneDecksing

    4 Novoseek inferred disease relationships for THRSP gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    thyroid diseases 31.5 1 8767512 (1)
    breast cancer 18.3 20 16300755 (5), 16809441 (5), 19116881 (4), 16552628 (3) (see all 5)
    metastasis 0 2 16552628 (1), 16809441 (1)
    tumors 0 8 16552628 (3), 16300755 (2), 9618526 (1)

    Genetic Association Database (GAD): THRSP
    Human Genome Epidemiology (HuGE) Navigator: THRSP (4 documents)

    Export disorders for THRSP gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for THRSP gene, integrated from 10 sources (see all 56):
    (articles sorted by number of sources associating them with THRSP)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Cloning and initial characterization of human and mouse Spot 14 genes. (PubMed id 9003802)1, 2, 3 Grillasca J.-P.... Planells R. (FEBS Lett. 1997)
    2. Human spot 14 protein interacts physically and functionally with the thyroid receptor. (PubMed id 17418816)1, 2, 9 Chou W.Y.... Huang S.M. (Biochem. Biophys. Res. Commun. 2007)
    3. Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. (PubMed id 20628086)1, 4 Bailey S.D....Anand S. (Diabetes Care 2010)
    4. Human Spot 14 protein is a p53-dependent transcriptional coactivator via the recruitment of thyroid receptor and Zac1. (PubMed id 18299245)1, 2 Chou W.Y.... Huang S.M. (Int. J. Biochem. Cell Biol. 2008)
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    6. Cloning, expression and regulation of the human S14 gene. (PubMed id 9027365)1, 9 Ota Y....Mariash C.N. (Mol. Cell. Endocrinol. 1997)
    7. The &quot;Spot 14&quot; gene resides on the telomeric end of the 11q13 amplicon and is expressed in lipogenic breast cancers: implications for control of tumor metabolism. (PubMed id 9618526)1, 9 Moncur J.T....Kinlaw W.B. (Proc. Natl. Acad. Sci. U.S.A. 1998)
    8. Expression, purification and preliminary crystallographic analysis of human thyroid hormone responsive protein. (PubMed id 21821901)1 Zhang W....Bartlam M. (Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. 2011)
    9. Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. (PubMed id 19913121)1 Talmud P.J.... . (Am. J. Hum. Genet. 2009)
    10. Toward a confocal subcellular atlas of the human proteome. (PubMed id 18029348)1 Barbe L....Andersson-Svahn H. (amp 2008)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 7069 HGNC: 11800 AceView: THRSP Ensembl:ENSG00000151365 euGenes: HUgn7069
    ECgene: THRSP H-InvDB: THRSP

    (According to HUGE)
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    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for THRSP Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for THRSP Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for THRSP gene:
    Search GeneIP for patents involving THRSP

    GeneCards and IP:
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