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Aliases for THRB Gene

Aliases for THRB Gene

  • Thyroid Hormone Receptor Beta 2 3 5
  • Thyroid Hormone Receptor, Beta (Erythroblastic Leukemia Viral (V-Erb-A) Oncogene Homolog 2, Avian) 2 3
  • Nuclear Receptor Subfamily 1 Group A Member 2 3 4
  • Oncogene ERBA2 2 3
  • C-ERBA-BETA 3 4
  • C-ERBA-2 3 4
  • ERBA2 3 4
  • NR1A2 3 4
  • THR1 3 4
  • Thyroid Hormone Receptor, Beta (Avian Erythroblastic Leukemia Viral (V-Erb-A) Oncogene Homolog 2) 2
  • Avian Erythroblastic Leukemia Viral (V-Erb-A) Oncogene Homolog 2 2
  • Thyroid Hormone Nuclear Receptor Beta Variant 1 3
  • Generalized Resistance To Thyroid Hormone 2
  • Pituitary Resistance To Thyroid Hormone 2
  • Thyroid Hormone Receptor Beta 1 2
  • Thyroid Hormone Receptor, Beta 2
  • THRB1 3
  • THRB2 3
  • GRTH 3
  • PRTH 3

External Ids for THRB Gene

Previous HGNC Symbols for THRB Gene

  • ERBA2
  • PRTH

Previous GeneCards Identifiers for THRB Gene

  • GC03M023830
  • GC03M024013
  • GC03M024138
  • GC03M024139
  • GC03M024158
  • GC03M024104

Summaries for THRB Gene

Entrez Gene Summary for THRB Gene

  • The protein encoded by this gene is a nuclear hormone receptor for triiodothyronine. It is one of the several receptors for thyroid hormone, and has been shown to mediate the biological activities of thyroid hormone. Knockout studies in mice suggest that the different receptors, while having certain extent of redundancy, may mediate different functions of thyroid hormone. Mutations in this gene are known to be a cause of generalized thyroid hormone resistance (GTHR), a syndrome characterized by goiter and high levels of circulating thyroid hormone (T3-T4), with normal or slightly elevated thyroid stimulating hormone (TSH). Several alternatively spliced transcript variants encoding the same protein have been observed for this gene. [provided by RefSeq, Jul 2008]

GeneCards Summary for THRB Gene

THRB (Thyroid Hormone Receptor Beta) is a Protein Coding gene. Diseases associated with THRB include Thyroid Hormone Resistance, Selective Pituitary and Thyroid Hormone Resistance. Among its related pathways are Thyroid hormone signaling pathway and Gene Expression. GO annotations related to this gene include transcription factor activity, sequence-specific DNA binding and enzyme binding. An important paralog of this gene is THRA.

UniProtKB/Swiss-Prot for THRB Gene

  • Nuclear hormone receptor that can act as a repressor or activator of transcription. High affinity receptor for thyroid hormones, including triiodothyronine and thyroxine.

Gene Wiki entry for THRB Gene

No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for THRB Gene

Genomics for THRB Gene

Regulatory Elements for THRB Gene

Enhancers for THRB Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH03F024448 1.4 Ensembl ENCODE 12.2 +43.0 43014 7.9 PKNOX1 MLX CREB3L1 ZFP64 ARID4B SIN3A DMAP1 ZNF2 YY1 ZNF416 THRB GC03M024442 THRB-IT1
GH03F024375 1.1 Ensembl ENCODE 5.9 +118.8 118760 1.1 SOX13 HDAC1 LEF1 ZFP64 CEBPG ZNF664 FOXK2 NCOR1 ZNF366 PRDM10 THRB PIR47305 GC03P024411 GC03M024338
GH03F024386 1 Ensembl ENCODE 6.2 +106.7 106716 3.7 PKNOX1 CEBPG FEZF1 ZNF2 ZKSCAN1 ZNF316 GATA3 POLR2A SCRT2 PRDM10 THRB GC03P024411 PIR47305 GC03M024338
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around THRB on UCSC Golden Path with GeneCards custom track

Promoters for THRB Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00001359545 582 3001 ZFP64 ARID4B SIN3A DMAP1 ZNF2 YY1 ZNF263 SP3 REST SMARCB1

Genomic Location for THRB Gene

Chromosome:
3
Start:
24,117,153 bp from pter
End:
24,495,282 bp from pter
Size:
378,130 bases
Orientation:
Minus strand

Genomic View for THRB Gene

Genes around THRB on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
THRB Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for THRB Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for THRB Gene

Proteins for THRB Gene

  • Protein details for THRB Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P10828-THB_HUMAN
    Recommended name:
    Thyroid hormone receptor beta
    Protein Accession:
    P10828
    Secondary Accessions:
    • B3KU79
    • P37243
    • Q13986
    • Q3KP35
    • Q6WGL2
    • Q9UD41

    Protein attributes for THRB Gene

    Size:
    461 amino acids
    Molecular mass:
    52788 Da
    Quaternary structure:
    • Binds DNA as a dimer; homodimer and heterodimer with RXRA. Interacts with the coactivators NCOA1/SRC1, NCOA2/GRIP1, NCOA7 and MED1/TRAP220 in a ligand-inducible manner. Interacts with the corepressor NCOR1 in absence of ligand. Interacts with C1D (By similarity). Interacts with NR2F6; the interaction impairs the binding of the THRB homodimer and THRB:RXRB heterodimer to T3 response elements. Interacts with PRMT2 and THRSP.
    SequenceCaution:
    • Sequence=AAA35677.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305}; Sequence=CAA28412.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305};

    Three dimensional structures from OCA and Proteopedia for THRB Gene

    Alternative splice isoforms for THRB Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for THRB Gene

Post-translational modifications for THRB Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for THRB Gene

Domains & Families for THRB Gene

Gene Families for THRB Gene

Graphical View of Domain Structure for InterPro Entry

P10828

UniProtKB/Swiss-Prot:

THB_HUMAN :
  • Composed of three domains: a modulating N-terminal domain, a DNA-binding domain and a C-terminal ligand-binding domain.
  • Belongs to the nuclear hormone receptor family. NR1 subfamily.
Domain:
  • Composed of three domains: a modulating N-terminal domain, a DNA-binding domain and a C-terminal ligand-binding domain.
  • Contains 1 nuclear receptor DNA-binding domain.
Family:
  • Belongs to the nuclear hormone receptor family. NR1 subfamily.
genes like me logo Genes that share domains with THRB: view

Function for THRB Gene

Molecular function for THRB Gene

GENATLAS Biochemistry:
thyroid hormone receptor,beta,essential for inner ear development,steroid/thyroid hormone receptor superfamily
UniProtKB/Swiss-Prot Function:
Nuclear hormone receptor that can act as a repressor or activator of transcription. High affinity receptor for thyroid hormones, including triiodothyronine and thyroxine.

Gene Ontology (GO) - Molecular Function for THRB Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding IEA,TAS 1618799
GO:0003700 transcription factor activity, sequence-specific DNA binding IEA,NAS 1618799
GO:0003707 steroid hormone receptor activity IEA --
GO:0003714 transcription corepressor activity TAS 1618799
GO:0004887 thyroid hormone receptor activity IEA,IDA 15466465
genes like me logo Genes that share ontologies with THRB: view
genes like me logo Genes that share phenotypes with THRB: view

Human Phenotype Ontology for THRB Gene

HPO Id HPO Name Alternative Ids Definition Synonyms

Animal Models for THRB Gene

MGI Knock Outs for THRB:

Animal Model Products

Targeted motifs for THRB Gene
HOMER Transcription Factor Regulatory Elements motif THRB
  • Consensus sequence: TRAGGTCA Submotif: canonical Cell Type: Liver GEO ID: GSE52613

Inhibitory RNA Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) and Transcription Factor Targets for THRB Gene

Localization for THRB Gene

Subcellular locations from UniProtKB/Swiss-Prot for THRB Gene

Nucleus.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for THRB gene
Compartment Confidence
extracellular 5
nucleus 5
mitochondrion 1
peroxisome 1

Gene Ontology (GO) - Cellular Components for THRB Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000790 nuclear chromatin IEA --
GO:0005634 nucleus IDA --
GO:0005654 nucleoplasm TAS --
GO:0070062 extracellular exosome IDA 23376485
genes like me logo Genes that share ontologies with THRB: view

Pathways & Interactions for THRB Gene

genes like me logo Genes that share pathways with THRB: view

Pathways by source for THRB Gene

SIGNOR curated interactions for THRB Gene

Is activated by:
Is inactivated by:

Gene Ontology (GO) - Biological Process for THRB Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000122 negative regulation of transcription from RNA polymerase II promoter IEA --
GO:0006351 transcription, DNA-templated IEA,TAS 1618799
GO:0006355 regulation of transcription, DNA-templated IEA --
GO:0006357 regulation of transcription from RNA polymerase II promoter IEA --
GO:0006367 transcription initiation from RNA polymerase II promoter TAS --
genes like me logo Genes that share ontologies with THRB: view

Drugs & Compounds for THRB Gene

(47) Drugs for THRB Gene - From: DrugBank, ApexBio, DGIdb, IUPHAR, HMDB, and Novoseek

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
Dextrothyroxine Approved Pharma Target, agonist 0
Liothyronine Approved, Vet_approved Pharma antagonist, Target, agonist 0
Levothyroxine Approved Pharma antagonist, Target, agonist 0
Liotrix Approved Pharma Target, agonist 0
[3,5-Dibromo-4-(4-Hydroxy-3-Phenethylcarbamoyl-Phenoxy)-Phenyl]-Acetic Acid Experimental Pharma Target 0

(13) Additional Compounds for THRB Gene - From: IUPHAR and Novoseek

Name Synonyms Role CAS Number PubChem IDs PubMed IDs
3,3,5-triiodothyroacetic acid
Agonist
reverse triiodothyronine
Agonist
T3
Agonist
T4
Agonist

(4) ApexBio Compounds for THRB Gene

Compound Action Cas Number
Aminothiazole 96-50-4
Liothyronine Sodium 1955-06-1
Sobetirome Agonist of tyroid hormone receptor 211110-63-3
Tiratricol 51-24-1
genes like me logo Genes that share compounds with THRB: view

Transcripts for THRB Gene

Unigene Clusters for THRB Gene

Thyroid hormone receptor, beta:
Representative Sequences:

Inhibitory RNA Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for THRB Gene

ExUns: 1 ^ 2 ^ 3 ^ 4a · 4b ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12a · 12b
SP1: -
SP2: -
SP3: - - -

Relevant External Links for THRB Gene

GeneLoc Exon Structure for
THRB
ECgene alternative splicing isoforms for
THRB

Expression for THRB Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for THRB Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for THRB Gene

This gene is overexpressed in Brain - Frontal Cortex (BA9) (x4.2).

Protein differential expression in normal tissues from HIPED for THRB Gene

This gene is overexpressed in Platelet (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for THRB Gene



Protein tissue co-expression partners for THRB Gene

NURSA nuclear receptor signaling pathways regulating expression of THRB Gene:

THRB

SOURCE GeneReport for Unigene cluster for THRB Gene:

Hs.187861
genes like me logo Genes that share expression patterns with THRB: view

Primer Products

No data available for mRNA Expression by UniProt/SwissProt for THRB Gene

Orthologs for THRB Gene

This gene was present in the common ancestor of chordates.

Orthologs for THRB Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia THRB 34 35
  • 99.71 (n)
dog
(Canis familiaris)
Mammalia THRB 34 35
  • 95.23 (n)
mouse
(Mus musculus)
Mammalia Thrb 34 16 35
  • 90.6 (n)
cow
(Bos Taurus)
Mammalia THRB 34 35
  • 90.41 (n)
rat
(Rattus norvegicus)
Mammalia Thrb 34
  • 89.59 (n)
oppossum
(Monodelphis domestica)
Mammalia THRB 35
  • 88 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia THRB 35
  • 66 (a)
OneToOne
chicken
(Gallus gallus)
Aves THRB 34 35
  • 88.32 (n)
lizard
(Anolis carolinensis)
Reptilia THRB 35
  • 68 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia thrb 34
  • 81.16 (n)
African clawed frog
(Xenopus laevis)
Amphibia LOC397734 34
zebrafish
(Danio rerio)
Actinopterygii thrb 34 35
  • 78.29 (n)
sea squirt
(Ciona savignyi)
Ascidiacea CSA.4364 35
  • 27 (a)
OneToMany
Species where no ortholog for THRB was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for THRB Gene

ENSEMBL:
Gene Tree for THRB (if available)
TreeFam:
Gene Tree for THRB (if available)

Paralogs for THRB Gene

Variants for THRB Gene

Sequence variations from dbSNP and Humsavar for THRB Gene

SNP ID Clin Chr 03 pos Sequence Context AA Info Type
rs121918686 Generalized thyroid hormone resistance (GTHR) [MIM:188570], Generalized thyroid hormone resistance (GTHR) [MIM:188570], Pathogenic 24,127,610(-) ATGGG(A/C/G)GTCTT reference, missense
rs121918687 Generalized thyroid hormone resistance (GTHR) [MIM:188570], Pathogenic 24,122,912(-) CCCCC(A/C)TTTGT reference, missense
rs121918688 Generalized thyroid hormone resistance (GTHR) [MIM:188570], Pathogenic 24,127,623(-) GGCCA(A/C/G)CTGAA reference, synonymous-codon, missense
rs121918690 Generalized thyroid hormone resistance (GTHR) [MIM:188570], Pathogenic 24,127,694(-) TTCGC(A/G)CTGCT reference, missense
rs121918691 Generalized thyroid hormone resistance (GTHR) [MIM:188570], Pathogenic 24,122,946(-) TGCAC(A/G)TGAAG reference, missense

Structural Variations from Database of Genomic Variants (DGV) for THRB Gene

Variant ID Type Subtype PubMed ID
nsv507088 OTHER sequence alteration 20534489
nsv476876 CNV novel sequence insertion 20440878
nsv3733 CNV deletion 18451855
nsv1012975 CNV gain 25217958
esv7101 CNV loss 19470904
esv3595579 CNV loss 21293372
esv3595578 CNV loss 21293372
esv3595575 CNV loss 21293372
esv3595574 CNV loss 21293372
esv3595572 CNV loss 21293372
esv3595571 CNV loss 21293372
esv3568649 CNV loss 25503493
esv3394628 CNV insertion 20981092
esv3384500 CNV duplication 20981092
esv3307476 CNV mobile element insertion 20981092
esv2725046 CNV deletion 23290073
esv2725045 CNV deletion 23290073
esv2725044 CNV deletion 23290073
esv2725043 CNV deletion 23290073
esv2677194 CNV deletion 23128226
esv2288146 CNV deletion 18987734
dgv765e201 CNV deletion 23290073
dgv74n68 CNV gain 17160897
dgv278n21 CNV loss 19592680
nsv999384 CNV gain 25217958
nsv834640 CNV gain 17160897
nsv834639 CNV gain 17160897
nsv528341 CNV gain 19592680
nsv527561 CNV loss 19592680
nsv524922 CNV loss 19592680
nsv522159 CNV loss 19592680
nsv520648 CNV loss 19592680

Variation tolerance for THRB Gene

Residual Variation Intolerance Score: 34.6% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.64; 13.69% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for THRB Gene

Human Gene Mutation Database (HGMD)
THRB
SNPedia medical, phenotypic, and genealogical associations of SNPs for
THRB

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for THRB Gene

Disorders for THRB Gene

MalaCards: The human disease database

(15) MalaCards diseases for THRB Gene - From: OMIM, ClinVar, GeneTests, Orphanet, Swiss-Prot, DISEASES, Novoseek, and GeneCards

Disorder Aliases PubMed IDs
thyroid hormone resistance, selective pituitary
  • selective pituitary resistance to thyroid hormone
thyroid hormone resistance
  • thyroid hormone resistance syndrome
thyroid hormone resistance, autosomal recessive
  • generalized thyroid hormone resistance autosomal recessive
generalized resistance to thyroid hormone
  • grth
hypothyroidism, congenital, nongoitrous, 3
  • peripheral resistance to thyroid hormones
- elite association - COSMIC cancer census association via MalaCards
Search THRB in MalaCards View complete list of genes associated with diseases

UniProtKB/Swiss-Prot

THB_HUMAN
  • Generalized thyroid hormone resistance (GTHR) [MIM:188570]: A disease characterized by goiter, abnormal mental functions, increased susceptibility to infections, abnormal growth and bone maturation, tachycardia and deafness. Affected individuals may also have attention deficit-hyperactivity disorders (ADHD) and language difficulties. GTHR patients also have high levels of circulating thyroid hormones (T3-T4), with normal or slightly elevated thyroid stimulating hormone (TSH). {ECO:0000269 PubMed:10660344, ECO:0000269 PubMed:1314846, ECO:0000269 PubMed:1324420, ECO:0000269 PubMed:1563081, ECO:0000269 PubMed:1587388, ECO:0000269 PubMed:1619012, ECO:0000269 PubMed:1661299, ECO:0000269 PubMed:16804041, ECO:0000269 PubMed:1846005, ECO:0000269 PubMed:19268523, ECO:0000269 PubMed:2153155, ECO:0000269 PubMed:2510172, ECO:0000269 PubMed:7833659, ECO:0000269 PubMed:8175986, ECO:0000269 PubMed:8514853, ECO:0000269 PubMed:8664910, ECO:0000269 PubMed:8889584}. Note=The disease is caused by mutations affecting the gene represented in this entry.
  • Generalized thyroid hormone resistance autosomal recessive (GTHRAR) [MIM:274300]: An autosomal recessive disorder characterized by goiter, clinical euthyroidism, end-organ unresponsiveness to thyroid hormone, abnormal growth and bone maturation, and deafness. Patients also have high levels of circulating thyroid hormones, with elevated thyroid stimulating hormone. {ECO:0000269 PubMed:1653889}. Note=The disease is caused by mutations affecting the gene represented in this entry.
  • Selective pituitary thyroid hormone resistance (PRTH) [MIM:145650]: Variant form of thyroid hormone resistance and is characterized by clinical hyperthyroidism, with elevated free thyroid hormones, but inappropriately normal serum TSH. Unlike GRTH, where the syndrome usually segregates with a dominant allele, the mode of inheritance in PRTH has not been established. {ECO:0000269 PubMed:7528740, ECO:0000269 PubMed:8381821}. Note=The disease is caused by mutations affecting the gene represented in this entry.

Relevant External Links for THRB

Genetic Association Database (GAD)
THRB
Human Genome Epidemiology (HuGE) Navigator
THRB
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
THRB
genes like me logo Genes that share disorders with THRB: view

No data available for Genatlas for THRB Gene

Publications for THRB Gene

  1. Genotyping of resistance to thyroid hormone in South American population. Identification of seven novel missense mutations in the human thyroid hormone receptor beta gene. (PMID: 19268523) Rivolta C.M. … Targovnik H.M. (Mol. Cell. Probes 2009) 3 4 22 64
  2. Identification and consequences of polymorphisms in the thyroid hormone receptor alpha and beta genes. (PMID: 18844476) SA … Visser T.J. (Thyroid 2008) 3 22 46 64
  3. Multiple messenger ribonucleic acid variants regulate cell-specific expression of human thyroid hormone receptor beta1. (PMID: 15105435) Frankton S. … Williams G.R. (Mol. Endocrinol. 2004) 3 4 22 64
  4. Thyroid hormone receptors/THR genes in human cancer. (PMID: 12668276) GonzA!lez-Sancho J.M. … MuA+oz A. (Cancer Lett. 2003) 3 22 25 64
  5. T426I a new mutation in the thyroid hormone receptor gene in a sporadic patient with resistance to thyroid hormone and dysmorphism. (PMID: 10660344) Menzaghi C. … de Filippis V. (Hum. Mutat. 1998) 3 4 22 64

Products for THRB Gene

Sources for THRB Gene

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