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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

THRAP3 Gene

protein-coding   GIFtS: 51
GCID: GC01P036690

Thyroid Hormone Receptor Associated Protein 3

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Thyroid Hormone Receptor Associated Protein 31 2
Thyroid Hormone Receptor-Associated Protein Complex 150 KDa Component2 3
TRAP1502 3
Thyroid Hormone Receptor-Associated Protein 32
Thyroid Hormone Receptor-Associated Protein, 150 KDa Subunit2
Trap1503

External Ids:    HGNC: 229641   Entrez Gene: 99672   Ensembl: ENSG000000541187   OMIM: 6038095   UniProtKB: Q9Y2W13   

Export aliases for THRAP3 gene to outside databases

Previous GC identifers: GC01P036117 GC01P036359 GC01P036462 GC01P034807


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for THRAP3 Gene: 
THRAP3 (thyroid hormone receptor associated protein 3) is a protein-coding gene. Diseases associated with THRAP3 include thyroiditis, and dermatofibrosarcoma, and among its related super-pathways are PGC1Alpha Pathway. GO annotations related to this gene include transcription coactivator activity and transcription cofactor activity. An important paralog of this gene is CXorf23.

UniProtKB/Swiss-Prot: TR150_HUMAN, Q9Y2W1
Function: Involved in pre-mRNA splicing. Remains associated with spliced mRNA after splicing which probably
involves interactions with the exon junction complex (EJC). Can trigger mRNA decay which seems to be indepenedent
of nonsense-mediated decay involving premature stop codons (PTC) recognition. May be involved in nuclear mRNA
decay. Involved in regulation of signal-induced alternative splicing. During splicing of PTPRC/CD45 is proposed
to sequester phosphorylated SFPQ from PTPRC/CD45 pre-mRNA in resting T-cells. Involved in cyclin-D1/CCND1 mRNA
stability probably by acting as component of the SNARP complex which associates with both the 3'end of the CCND1
gene and its mRNA. Involved in response to DNA damage. Is excluced from DNA damage sites in a manner that
parallels transcription inhibition; the function may involve the SNARP complex. Initially thought to play a role
in transcriptional coactivation through its association with the TRAP complex; however, it is not regarded as a
stable Mediator complex subunit

Gene Wiki entry for THRAP3 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000001.10  NT_032977.9  NC_018912.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the THRAP3 gene promoter:
         CREB   AREB6   STAT1   Spz1   FOXO4   deltaCREB   COMP1   Sox9   Msx-1   C/EBPalpha   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidTHRAP3 promoter sequence
   Search SABiosciences Chromatin IP Primers for THRAP3

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat THRAP3


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1p34.3   Ensembl cytogenetic band:  1p34.3   HGNC cytogenetic band: 1p34.3

THRAP3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
THRAP3 gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01P036690:  view genomic region     (about GC identifiers)

Start:
36,690,017 bp from pter      End:
36,770,958 bp from pter
Size:
80,942 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: TR150_HUMAN, Q9Y2W1 (See protein sequence)
Recommended Name: Thyroid hormone receptor-associated protein 3  
Size: 955 amino acids; 108666 Da
Subunit: Associated with the large multiprotein complex TRAP (Mediator complex-like). Interacts with SFPQ; the
interaction is dependent on SFPQ phosphorylation at 'Thr-687' and inhibits binding of SFPQ to an ESS1 exonic
splicing silencer element-containing RNA. Interacts with NXF1. Component of the SNARP complex which consists at
least of SNIP1, SNW1, THRAP3, BCLAF1 and PNN. Associated with spliced mRNP complexes
Subcellular location: Nucleus
Sequence caution: Sequence=AAH37554.1; Type=Miscellaneous discrepancy; Note=Contaminating sequence. Potential
poly-A sequence;
Secondary accessions: D3DPS5 Q5VTK6

Explore the universe of human proteins at neXtProt for THRAP3: NX_Q9Y2W1

Explore proteomics data for THRAP3 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q9Y2W1

  • THRAP3 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    THRAP3 Protein Expression
    REFSEQ proteins: NP_005110.2  
    ENSEMBL proteins: 
     ENSP00000346634   ENSP00000433825   ENSP00000433066  

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    Cloud-Clone Corp. Proteins for THRAP3 

    Gene Ontology (GO): 5 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA--
    GO:0005730NOT nucleolus IDA--
    GO:0016592mediator complex IDA10198638
    GO:0035145colocalizes with exon-exon junction complex IDA--
    GO:0043231intracellular membrane-bounded organelle IDA--

    THRAP3 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    1 InterPro protein domain:
     IPR026667 THRAP3

    Graphical View of Domain Structure for InterPro Entry Q9Y2W1

    ProtoNet protein and cluster: Q9Y2W1


    THRAP3 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: TR150_HUMAN, Q9Y2W1
    Function: Involved in pre-mRNA splicing. Remains associated with spliced mRNA after splicing which probably
    involves interactions with the exon junction complex (EJC). Can trigger mRNA decay which seems to be indepenedent
    of nonsense-mediated decay involving premature stop codons (PTC) recognition. May be involved in nuclear mRNA
    decay. Involved in regulation of signal-induced alternative splicing. During splicing of PTPRC/CD45 is proposed
    to sequester phosphorylated SFPQ from PTPRC/CD45 pre-mRNA in resting T-cells. Involved in cyclin-D1/CCND1 mRNA
    stability probably by acting as component of the SNARP complex which associates with both the 3'end of the CCND1
    gene and its mRNA. Involved in response to DNA damage. Is excluced from DNA damage sites in a manner that
    parallels transcription inhibition; the function may involve the SNARP complex. Initially thought to play a role
    in transcriptional coactivation through its association with the TRAP complex; however, it is not regarded as a
    stable Mediator complex subunit

         Gene Ontology (GO): 5/10 molecular function terms (GO ID links to tree view) (see all 10):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0001104RNA polymerase II transcription cofactor activity IDA10198638
    GO:0003712transcription cofactor activity IDA12218053
    GO:0003713transcription coactivator activity IDA12037571
    GO:0004872receptor activity IDA12218053
    GO:0005515protein binding IPI18596238
         
    THRAP3 for ontologies           About GeneDecksing


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    SwitchGear 3'UTR luciferase reporter plasmidTHRAP3 3' UTR sequence
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for THRAP3 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1PEDF Induced Signaling
    Glucocorticoid Receptor Signaling0.43

    1 Downloadable PowerPoint Slide of QIAGEN Pathway Central Maps for THRAP3
        Glucocorticoid Receptor Signaling


    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for THRAP3

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/828 Interacting proteins for THRAP3 (Q9Y2W11, 2, 3 ENSP000003466344) via UniProtKB, MINT, STRING, and/or I2D (see all 828)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    SMN1Q166372, 3, ENSP000003700834MINT-7945693 MINT-7947479 I2D: score=2 STRING: ENSP00000370083
    SMN2Q166372, 3, ENSP000003701194MINT-7945693 MINT-7947479 I2D: score=2 STRING: ENSP00000370119
    SNW1Q135731, 2, ENSP000002615314EBI-352039,EBI-632715 MINT-7945693 MINT-7947479 STRING: ENSP00000261531
    PARP1P098742, 3, ENSP000003557594MINT-7947479 I2D: score=1 STRING: ENSP00000355759
    EIF4A3P389191, 2EBI-352039,EBI-299104 MINT-7945693 MINT-7947479
    About this table

    Gene Ontology (GO): 5/11 biological process terms (GO ID links to tree view) (see all 11):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000381regulation of alternative mRNA splicing, via spliceosome IMP--
    GO:0000956nuclear-transcribed mRNA catabolic process IDA--
    GO:0006367transcription initiation from RNA polymerase II promoter IDA12218053
    GO:0006397mRNA processing IEA--
    GO:0008380RNA splicing IEA--

    THRAP3 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for THRAP3 (TR150)

    Search CenterWatch for drugs/clinical trials and news about THRAP3 / TR150

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for THRAP3 gene: 
    NM_005119.3  

    Unigene Cluster for THRAP3:

    Thyroid hormone receptor associated protein 3
    Hs.744057  [show with all ESTs]
    Unigene Representative Sequence: NM_005119
    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000354618(uc001cae.4 uc001caf.4) ENST00000469141(uc001cag.1)
    ENST00000478853 ENST00000466743
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    SwitchGear 3'UTR luciferase reporter plasmidTHRAP3 3' UTR sequence
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    Additional mRNA sequence: 

    AF117756.1 AK025220.1 AK025408.1 AK025735.1 BC002501.2 BC010997.2 BC019076.1 BC037554.2 
    BC054046.1 BC065519.1 BC112330.1 BC112350.1 

    22 DOTS entries:

    DT.91947580  DT.87018401  DT.92035388  DT.40131847  DT.121392965  DT.100800838  DT.101984679  DT.95131158 
    DT.97861950  DT.101955858  DT.121392979  DT.97816757  DT.40271586  DT.95248820  DT.95248824  DT.102834090 
    DT.120876815  DT.40196983  DT.91749842  DT.91758425  DT.91893925  DT.91950369 

    24/363 AceView cDNA sequences (see all 363):

    AI570614 BQ049854 AI863765 AI336933 BM699415 BC010997 BC065519 BM068748 
    BP378413 AA357063 AI090560 BM803628 BI871391 AW239179 AI474719 AI632875 
    BP360521 AI301804 BC019076 BE328388 AI857918 BG392340 AI439504 BM715795 

    GeneLoc Exon Structure

    5/8 Alternative Splicing Database (ASD) splice patterns (SP) for THRAP3 (see all 8)    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7a · 7b ^ 8 ^ 9 ^ 10 ^ 11a · 11b ^ 12 ^ 13 ^ 14 ^ 15 ^ 16
    SP1:                                                                                                                  
    SP2:                                                                                                                  
    SP3:              -     -     -                                                                                       
    SP4:                                                                                                                  
    SP5:                                                                                                                  


    ECgene alternative splicing isoforms for THRAP3

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    THRAP3 expression in normal human tissues (normalized intensities)      THRAP3 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TTTAGGGGGA
    THRAP3 Expression
    About this image


    THRAP3 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/35 selected tissues (see all 35) fully expand
     
     Epithelium
             vagina ; squamous epithelial cells   
     
     Uterus
             uterus, post-menopause ; glandular cells   
     
     Testis (Reproductive System)    fully expand to see all 4 entries
             Leydig Cells Testis Interstitium
             seminal vesicle ; glandular cells   
     
     Colon (Gastrointestinal Tract)    fully expand to see all 4 entries
             colon ; peripheral nerve/ganglion   
     
     Brain (Nervous System)    fully expand to see all 4 entries
             Cerebral Cortex

    See THRAP3 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for THRAP3

    SOURCE GeneReport for Unigene cluster: Hs.744057

    UniProtKB/Swiss-Prot: TR150_HUMAN, Q9Y2W1
    Tissue specificity: Ubiquitous

        SABiosciences Expression via Pathway-Focused PCR Array including THRAP3: 
              Cardiotoxicity in human mouse rat

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    In Situ
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for THRAP3

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for THRAP3 gene from 5/13 species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Thrap31 , 5 thyroid hormone receptor associated protein 31, 5 89.72(n)1
    93.88(a)1
      4 (60.00 cM)5
    2307531  NM_146153.31  NP_666265.31 
     1261640825 
    chicken
    (Gallus gallus)
    Aves THRAP31 thyroid hormone receptor associated protein 3 75.9(n)
    81.16(a)
      419623  NM_001030899.1  NP_001026070.1 
    lizard
    (Anolis carolinensis)
    Reptilia THRAP36
    thyroid hormone receptor associated protein 3
    74(a)
    1 ↔ 1
    GL343481.1(48324-78614)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.77452 Xenopus laevis, Similar to thyroid hormone receptor-associated more 74.97(n)    BC041220.1 
    zebrafish
    (Danio rerio)
    Actinopterygii CK027497.12   -- 74.07(n)   335042  CK027497.1 


    ENSEMBL Gene Tree for THRAP3 (if available)
    TreeFam Gene Tree for THRAP3 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for THRAP3 gene
    CXorf232  BCLAF12  
    1 SIMAP similar gene for THRAP3 using alignment to 6 protein entries:     TR150_HUMAN (see all proteins):
    BCLAF1

    THRAP3 for paralogs           About GeneDecksing


    3 Pseudogenes.org Pseudogenes for THRAP3
    PGOHUM00000246929 PGOHUM00000237977 PGOHUM00000232593


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/1719 SNPs in THRAP3 are shown (see all 1719)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1500981011,2
    --36688131(+) GCCTCC/TTGAGT 1 -- us2k10--------
    rs747547981,2
    C,F--36688164(+) CACCAC/TGCCCG 1 -- us2k11Minor allele frequency- T:0.50WA 2
    rs1879905571,2
    C--36688172(+) CCGGCA/TAATCT 1 -- us2k10--------
    rs1151215551,2
    F--36688173(+) CGGCTA/GATCTG 1 -- us2k11Minor allele frequency- G:0.01NA 120
    rs1808556021,2
    --36688181(+) CTGTAA/GTATTT 1 -- us2k10--------
    rs1167181631,2
    F--36688229(+) ATCACG/AAACTC 1 -- us2k11Minor allele frequency- A:0.02NA 120
    rs120821471,2
    C,H--36688421(+) ACCCAG/TAAAAT 1 -- us2k15Minor allele frequency- T:0.00NS EA NA 420
    rs726634031,2
    C--36688546(+) CCAACA/GTGGCG 1 -- us2k10--------
    rs1886135801,2
    C--36688674(+) AGTGAC/GCCAAA 1 -- us2k10--------
    rs755063571,2
    C--36688755(+) AATAAA/TATCAA 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for THRAP3 (36690017 - 36770958 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 10/15 variations for THRAP3 (see all 15):    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2746830CNV Deletion23290073
    esv1002750CNV Deletion20482838
    esv1414937CNV Deletion17803354
    esv2746852CNV Deletion23290073
    esv2746863CNV Deletion23290073
    esv2544592CNV Deletion19546169
    esv2663119CNV Deletion23128226
    esv2746841CNV Deletion23290073
    esv2045078CNV Deletion18987734
    esv2125715CNV Deletion18987734

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 603809    OMIM disorders: --

    3 diseases for THRAP3:    About MalaCards
    thyroiditis    dermatofibrosarcoma    breast cancer


    THRAP3 for disorders           About GeneDecksing


    Export disorders for THRAP3 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for THRAP3 gene, integrated from 9 sources (see all 73):
    (articles sorted by number of sources associating them with THRAP3)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Proteomic investigations reveal a role for RNA process ing factor THRAP3 in the DNA damage response. (PubMed id 22424773)1, 2 Beli P....Choudhary C. (2012)
    2. Regulation of cyclin D1 RNA stability by SNIP1. (PubMed id 18794151)1, 2 Bracken C.P....Perkins N.D. (2008)
    3. A probability-based approach for high-throughput protein phosphorylation analysis and site localization. (PubMed id 16964243)1, 2 Beausoleil S.A.... Gygi S.P. (2006)
    4. The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)1, 2 Gregory S.G.... Bentley D.R. (2006)
    5. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (2006)
    6. Robust phosphoproteomic profiling of tyrosine phosphorylation sites from human T cells using immobilized metal affinity chromatography and tandem mass spectrometry. (PubMed id 15144186)1, 2 Brill L.M....Peters E.C. (2004)
    7. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    8. Identity between TRAP and SMCC complexes indicates novel pathways for the function of nuclear receptors and diverse mammalian activators. (PubMed id 10198638)1, 2 Ito M.... Roeder R.G. (1999)
    9. Interlaboratory reproducibility of large-scale human p rotein-complex analysis by standardized AP-MS. (PubMed id 23455922)1 Varjosalo M....Superti-Furga G. (2013)
    10. Deubiquitinase FAM/USP9X interacts with the E3 ubiquit in ligase SMURF1 protein and protects it from ligase activity-dependent self-deg radation. (PubMed id 23184937)1 Xie Y....Cong F. (2013)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
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      Query String
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      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 9967 HGNC: 22964 AceView: THRAP3 Ensembl:ENSG00000054118 euGenes: HUgn9967
    ECgene: THRAP3 H-InvDB: THRAP3

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for THRAP3 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for THRAP3 Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for THRAP3 gene:
    Search GeneIP for patents involving THRAP3

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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