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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

THOC6 Gene

protein-coding   GIFtS: 48
GCID: GC16P003113

THO complex 6 homolog (Drosophila)

(Previous name: WD repeat domain 58 )
(Previous symbol: WDR58)
 Explore 3 diseases affiliated with
THOC6 via our new
 Human Malady Compendium 
Biological research products
for THOC6
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
THO Complex 6 Homolog (Drosophila)1 2     Functional Spliceosome-Associated Protein 352 3
WDR581 2 3     WD Repeat-Containing Protein 582 3
FSAP351     MGC26551
WD Repeat Domain 581 2     THO Complex Subunit 6 Homolog2

External Ids:    HGNC: 283691   Entrez Gene: 792282   Ensembl: ENSG000001316527   UniProtKB: Q86W423   

Export aliases for THOC6 gene to outside databases

Previous GC identifers: GC16P003017 GC16P003079 GC16P003045 GC16P003080 GC16P003081


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: THOC6_HUMAN, Q86W42
Function: Component of the THO subcomplex of the TREX complex. The TREX complex specifically associates with spliced
mRNA and not with unspliced pre-mRNA. It is recruited to spliced mRNAs by a transcription-independent mechanism. Binds
to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a
region near the 5' end of the mRNA where it functions in mRNA export. The recruitment occurs via an interaction
between ALYREF/THOC4 and the cap-binding protein NCBP1. DDX39B functions as a bridge between ALYREF/THOC4 and the THO
complex. The TREX complex is essential for the export of Kaposi's sarcoma-associated herpesvirus (KSHV) intronless
mRNAs and infectious virus production. The recruitment of the TREX complex to the intronless viral mRNA occurs via an
interaction between KSHV ORF57 protein and ALYREF/THOC4




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000016.9  NC_018927.1  NT_010393.16  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the THOC6 gene promoter:
         COUP-TF1   COUP-TF   AP-1   ATF-2   COUP   HNF-4alpha2   c-Jun   HNF-4alpha1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidTHOC6 promoter sequence
   Search SABiosciences Chromatin IP Primers for THOC6

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat THOC6


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 16p13.3   Ensembl cytogenetic band:  16p13.3   HGNC cytogenetic band: 16p13.3

THOC6 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
THOC6 gene location

GeneLoc information about chromosome 16         GeneLoc Exon Structure

GeneLoc location for GC16P003113:  view genomic region     (about GC identifiers)

Start:
3,074,028 bp from pter      End:
3,077,756 bp from pter
Size:
3,729 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: THOC6_HUMAN, Q86W42 (See protein sequence)
Recommended Name: THO complex subunit 6 homolog  
Size: 341 amino acids; 37535 Da
Subunit: Component of the THO complex, which is composed of THOC1, THOC2, THOC5, THOC6 and THOC7. Together with THOC3,
ALYREF/THOC4 and DDX39B, THO forms the transcription/export (TREX) complex
Sequence caution: Sequence=BAG36782.1; Type=Erroneous initiation;
Secondary accessions: B2RA85 Q8NBR1 Q9BTV9
Alternative splicing: 3 isoforms:  Q86W42-1   Q86W42-2   Q86W42-3   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for THOC6: NX_Q86W42

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q86W42

  • THOC6 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins (2 alternative transcripts): 
    NP_001135822.1  NP_077315.2  

    ENSEMBL proteins: 
     ENSP00000326531   ENSP00000458295   ENSP00000460015   ENSP00000253952  

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    Novus Biologicals THOC6 Proteins
    Novus Biologicals THOC6 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins
    Uscn Proteins for THOC6

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000346transcription export complex IDA15998806
    GO:0000347THO complex IDA15998806
    GO:0000445THO complex part of transcription export complex IDA15998806


    THOC6 for ontologies           About GeneDecksing



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    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    THOC6 for domains           About GeneDecksing

    4 InterPro domains/families:
     IPR019775 WD40_repeat_CS
     IPR001680 WD40_repeat
     IPR017986 WD40_repeat_dom
     IPR015943 WD40/YVTN_repeat-like_dom

    Graphical View of Domain Structure for InterPro Entry Q86W42

    ProtoNet protein and cluster: Q86W42

    UniProtKB/Swiss-Prot: THOC6_HUMAN, Q86W42
    Similarity: Belongs to the WD repeat THOC6 family
    Similarity: Contains 7 WD repeats


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Function Summary:

         UniProtKB/Swiss-Prot: THOC6_HUMAN, Q86W42
    Function: Component of the THO subcomplex of the TREX complex. The TREX complex specifically associates with spliced
    mRNA and not with unspliced pre-mRNA. It is recruited to spliced mRNAs by a transcription-independent mechanism. Binds
    to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a
    region near the 5' end of the mRNA where it functions in mRNA export. The recruitment occurs via an interaction
    between ALYREF/THOC4 and the cap-binding protein NCBP1. DDX39B functions as a bridge between ALYREF/THOC4 and the THO
    complex. The TREX complex is essential for the export of Kaposi's sarcoma-associated herpesvirus (KSHV) intronless
    mRNAs and infectious virus production. The recruitment of the TREX complex to the intronless viral mRNA occurs via an
    interaction between KSHV ORF57 protein and ALYREF/THOC4

    miRNA
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for THOC6

    Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003723RNA binding IEA--


    THOC6 for ontologies           About GeneDecksing


    1 GenomeRNAi human phenotype for THOC6:
     Increased gamma-H2AX phosphory 


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1RNA transport
    RNA transport1.00

    Pathway sources
    See GeneCards unified pathways
    Show all pathways



    1         Kegg Pathway  (Kegg details for THOC6):
        RNA transport


    THOC6 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for THOC6

    STRING Interaction Network Preview (showing 5 interactants - click image to see 11)

    5/16 Interacting proteins for THOC6 (Q86W422, 3 ENSP000003265314) via UniProtKB, MINT, STRING, and/or I2D (see all 16)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    THOC5Q137692, ENSP000003809694MINT-7040334 MINT-7040353 MINT-7040368 STRING: ENSP00000380969
    THOC1Q96FV92, ENSP000002616004MINT-7040334 MINT-7040353 MINT-7040368 STRING: ENSP00000261600
    THOC2Q8NI272, ENSP000002458384MINT-7040353 MINT-7040368 STRING: ENSP00000245838
    ESR2Q927313, ENSP000003439254I2D: score=1 STRING: ENSP00000343925
    RNF2Q994963I2D: score=2 
    About this table

    Gene Ontology (GO): 4 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006397mRNA processing IEA--
    GO:0006406mRNA export from nucleus IDA17190602
    GO:0008380RNA splicing IEA--
    GO:0046784intronless viral mRNA export from host nucleus IDA18974867


    THOC6 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for THOC6
    Search CenterWatch for drugs/clinical trials and news about THOC6 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for THOC6 gene (2 alternative transcripts): 
    NM_001142350.1  NM_024339.3  

    Unigene Cluster for THOC6:

    THO complex 6 homolog (Drosophila)
    Hs.412304  [show with all ESTs]
    Unigene Representative Sequence: BQ057555
    10 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000576143 ENST00000574957 ENST00000326266(uc002ctb.2 uc002ctd.2)
    ENST00000574549(uc002cta.2) ENST00000571057 ENST00000575576 ENST00000574498
    ENST00000573704 ENST00000253952 ENST00000571046

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    Additional cDNA sequence: 

    AK075330.1 AK308960.1 AK310113.1 AK314086.1 AL832548.1 BC003118.1 BC050674.1 

    14 DOTS entries:

    DT.408652  DT.92434369  DT.408651  DT.92434372  DT.100787603  DT.95289379  DT.100801859  DT.95084812 
    DT.120679707  DT.420514  DT.95079278  DT.100806086  DT.75103280  DT.92411825 

    24/168 AceView cDNA sequences (see all 168):

    BE266376 BX457909 BC050674 BQ056498 BE907583 BM562396 BM477797 BQ687640 
    CR624641 BQ233339 BM807893 BE407790 BI910103 BU931064 BQ931677 AA404589 
    BE740506 CA489681 BU855953 NM_024339 AK075330 BM928503 CR593456 BI488444 

    GeneLoc Exon Structure

    3 Alternative Splicing Database (ASD) splice patterns (SP) for THOC6    About this scheme

    ExUns: 1 ^ 2a · 2b ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11
    SP1:                                                                        
    SP2:                                                                        
    SP3:                                                                        


    ECgene alternative splicing isoforms for THOC6

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    THOC6 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: GTTTCCACCG

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)

    About this image
    See THOC6 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for THOC6

    SOURCE GeneReport for Unigene cluster: Hs.412304
        SABiosciences Custom PCR Arrays for THOC6
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for THOC6

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for THOC6 gene from 7/23 species (see all 23)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Thoc61 , 5 THO complex 6 homolog (Drosophila)1, 5 86.8(n)1
    95.31(a)1
      17 (11.97 cM)5
    3866121  NM_001008425.11  NP_001008425.11 
     236686145 
    lizard
    (Anolis carolinensis)
    Reptilia THOC66
    --
    68(a)
    1 ↔ 1
    GL343516.1(479604-488829)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia Str.144822 Transcribed sequence with weak similarity to protein more 71.5(n)    137728044 
    zebrafish
    (Danio rerio)
    Actinopterygii wufb96g042 Transcribed sequence with weak similarity to protein more 77.54(n)    BM317325.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta thoc61 CG5632-PA 43.4(n)
    29.87(a)
      39394  NM_140300.3  NP_648557.1 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons DWA11 THO complex subunit 6 43.7(n)
    34.98(a)
      816462  NM_179658.3  NP_849989.1 
    rice
    (Oryza sativa)
    Liliopsida Os09g03636001 hypothetical protein 47.22(n)
    38.02(a)
      4346861  NM_001069528.1  NP_001062993.1 


    ENSEMBL Gene Tree for THOC6 (if available)
    TreeFam Gene Tree for THOC6 (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/48 NCBI SNPs in THOC6 are shown (see all 48    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 16 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1174696831,2
    C,F,--3076331(+) TGAAGC/TCACTT 2 -- int12Minor allele frequency- T:0.01NA EU 1431
    rs344720801,2
    C,F,--3076369(-) AGGCTG/AGTCCT 4 /T syn12Minor allele frequency- A:0.00NA EU 1395
    rs80572621,2
    C,F,H,--3076393(+) ATCAAC/TGCTTT 4 N syn1 ese313Minor allele frequency- T:0.05NS NA WA CSA EU 7301
    rs1418622661,2
    C,--3076485(+) TGACAC/TTGACT 2 -- int10--------
    rs1387060381,2
    C,F--3076587(+) TTTCAC/TGGTGA 4 T M mis11Minor allele frequency- T:0.00NA 4548
    rs9602741,2
    C,F,H,--3076663(-) GGGGCG/AATGTC 2 -- int120Minor allele frequency- A:0.15MN EA NS NA EU 4449
    rs1493842721,2
    C,F--3076690(+) CCTCCG/AGGGCC 4 /Q /R mis11Minor allele frequency- A:0.00NA 4494
    rs1995509641,2
    --3076833(+) TGAGGC/GAAGTG 2 -- int10--------
    rs1484949491,2
    C--3076895(+) CCAGAC/TGATCG 4 T M mis11Minor allele frequency- T:0.00NA 4548
    rs2015523521,2
    --3076931(+) GTGACC/TGTGGC 2 -- int10--------

    HapMap Linkage Disequilibrium report for THOC6 (3074028 - 3077756 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for THOC6: --

    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing THOC6
    DNA2.0 Custom Variant and Variant Library Synthesis for THOC6

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    THOC6 for disorders           About GeneDecksing

    3 diseases for THOC6:    About MalaCards
    kaposi's sarcoma    sarcoma    breast cancer

    Human Genome Epidemiology (HuGE) Navigator: THOC6 (4 documents)

    Export disorders for THOC6 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for THOC6 gene, integrated from 9 sources (see all 18):
    (articles sorted by number of sources associating them with THOC6)
        Utopia: connect your pdf to the dynamic
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    1. Recruitment of the complete hTREX complex is required for Kaposi's sarcoma-associated herpesvirus intronless mRNA nuclear export and virus replication. (PubMed id 18974867)1, 2 Boyne J.R.... Whitehouse A. (2008)
    2. Human mRNA export machinery recruited to the 5' end of mRNA. (PubMed id 17190602)1, 2 Cheng H.... Reed R. (2006)
    3. Recruitment of the human TREX complex to mRNA during splicing. (PubMed id 15998806)1, 2 Masuda S.... Reed R. (2005)
    4. Linking transcriptional elongation and messenger RNA export to metastatic breast cancers. (PubMed id 15833825)1, 2 Guo S.... Shiekhattar R. (2005)
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    6. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (2002)
    7. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
    8. Host cell interactome of HIV-1 Rev includes RNA helica ses involved in multiple facets of virus production. (PubMed id 22174317)1 Naji S....Gerace L. (2012)
    9. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
    10. A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)

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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 79228 HGNC: 28369 AceView: MGC2655 Ensembl:ENSG00000131652 euGenes: HUgn79228
    ECgene: THOC6 Kegg: 79228 H-InvDB: THOC6

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for THOC6 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for THOC6 gene:
    Search GeneIP for patents involving THOC6

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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