THOC5 Gene
protein-coding GIFtS: 53
GCID: GC22M029901
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THO complex 5(Previous name: chromosome 22 open reading frame 19 ) (Previous symbol: C22orf19)
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Aliases for THOC5 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb) About This Section
|
| Aliases |
|---|
| THO Complex 51 2 | | PP39.22 3 | | C22orf191 2 3 | | HTREX901 | | FSAP791 | | NF2/Meningioma Region Protein PK1.32 3 | | Fmip1 2 | | Chromosome 22 Open Reading Frame 191 | | PK1.31 2 | | Fms-Interacting Protein2 | | KIAA09831 3 | | THO Complex Subunit 5 Homolog2 | | Functional Spliceosome-Associated Protein 792 3 | | FMIP5 | | Placental Protein 39.22 3 | | |
Export aliases for THOC5 gene to outside databasesPrevious GC identifers: GC00U902870 GC22M028231 GC22M012867 |
Summaries for THOC5 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
| UniProtKB/Swiss-Prot: THOC5_HUMAN, Q13769Function: Component the THO subcomplex of the TREX complex. The TREX complex specifically associates with spliced mRNAand not with unspliced pre-mRNA. It is recruited to spliced mRNAs by a transcription-independent mechanism. Binds tomRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a regionnear the 5' end of the mRNA where it functions in mRNA export. The recruitment occurs via an interaction betweenALYREF/THOC4 and the cap-binding protein NCBP1. The TREX complex is essential for the export of Kaposi'ssarcoma-associated herpesvirus (KSHV) intronless mRNAs and infectious virus production. The recruitment of the TREXcomplex to the intronless viral mRNA occurs via an interaction beteen KSHV ORF57 protein and ALYREF/THOC4. DDX39Bfunctions as a bridge between ALYREF/THOC4 and the THO complex. THOC5 in conjunction with ALYREF/THOC4 functions inNXF1-NXT1 mediated nuclear export of HSP70 mRNA. Regulates the expression of myeloid transcription factors CEBPA,CEBPB and GAB2 by enhancing the levels of phosphatidylinositol 3,4,5-trisphosphate. May be involved in thedifferentiation of granulocytes and adipocytes. Essential for hematopoietic primitive cell survival and plays anintegral role in monocytic development Gene Wiki entry for THOC5
|
Genomic Views for THOC5 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics) About This Section
| RefSeq DNA sequence:- NC_000022.10 NC_018933.1 NT_011520.12
Regulatory elements: SABiosciences Regulatory transcription factor binding sites in the THOC5 gene promoter: p53 ZID Tal-1beta E47 Other transcription factors
Search SABiosciences Chromatin IP Primers for THOC5
Epigenetics:
|  | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat THOC5 |
Genomic Location: Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 22q12.2 Ensembl cytogenetic band: 22q12.2 HGNC cytogenetic band: 22q12THOC5 Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different)

GeneLoc information about chromosome 22 GeneLoc Exon Structure GeneLoc location for GC22M029901: view genomic region
(about GC identifiers)
Start:
|
29,901,868 bp from pter |
End:
|
29,951,205 bp from pter |
Size:
|
49,338 bases |
Orientation:
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minus strand |
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Proteins for THOC5 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
| UniProtKB/Swiss-Prot: THOC5_HUMAN, Q13769 (See
protein sequence)Recommended Name: THO complex subunit 5 homolog Size: 683 amino acids; 78508 Da
Subunit: Interacts with phosphorylated CSF1R and THOC1 (By similarity). Component of the THO complex, which is composedof THOC1, THOC2, THOC5, THOC6 and THOC7. Together with THOC3, ALYREF/THOC4 and DDX39B, THO forms thetranscription/export (TREX) complex. Interacts with ALYREF/THOC4 and THOC7. Interacts (via N-terminus) with the NTF2domain of NXF1. Forms a complex with CEBPB (By similarity)
Subcellular location: Nucleus. Cytoplasm (By similarity). Note=Shuttles between nucleus and cytoplasm
Sequence caution: Sequence=BAA76827.2; Type=Erroneous initiation; Note=Translation N-terminally shortened;
Secondary accessions: O60839 Q9UPZ5Explore the universe of human proteins at neXtProt for THOC5: NX_Q13769
Post-translational modifications:
Phosphorylated on tyrosine upon binding to activated CSF1R; which causes a dissociation of the two proteins.Phosphorylation on Ser-5 and/or Ser-6 is required for nuclear export. Phosphorylated on Thr-328 in insulin-stimulatedadipocytes (By similarity)1
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q13769 THOC5 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (4 alternative transcripts):
NP_001002877.1 NP_001002878.1 NP_001002879.1 NP_003669.4 ENSEMBL proteins: ENSP00000420306 ENSP00000416500 ENSP00000444493 ENSP00000380971 ENSP00000393247 ENSP00000413505 ENSP00000415425 ENSP00000416804 ENSP00000393420 ENSP00000388039 ENSP00000380970 ENSP00000380969 Human Recombinant Protein Products:
Gene Ontology (GO): 5/8 cellular component terms (GO ID links to tree view) (see all 8): About this table
THOC5 for ontologies About GeneDecksing
THOC5 Antibody Products: Assay Products for THOC5: |
Protein
Domains / Families for THOC5 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
THOC5 for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry Q13769ProtoNet protein and cluster: Q13769 UniProtKB/Swiss-Prot: THOC5_HUMAN, Q13769Similarity: Belongs to the THOC5 family |
Function for THOC5 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
| Function Summary: UniProtKB/Swiss-Prot: THOC5_HUMAN, Q13769Function: Component the THO subcomplex of the TREX complex. The TREX complex specifically associates with spliced mRNAand not with unspliced pre-mRNA. It is recruited to spliced mRNAs by a transcription-independent mechanism. Binds tomRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a regionnear the 5' end of the mRNA where it functions in mRNA export. The recruitment occurs via an interaction betweenALYREF/THOC4 and the cap-binding protein NCBP1. The TREX complex is essential for the export of Kaposi'ssarcoma-associated herpesvirus (KSHV) intronless mRNAs and infectious virus production. The recruitment of the TREXcomplex to the intronless viral mRNA occurs via an interaction beteen KSHV ORF57 protein and ALYREF/THOC4. DDX39Bfunctions as a bridge between ALYREF/THOC4 and the THO complex. THOC5 in conjunction with ALYREF/THOC4 functions inNXF1-NXT1 mediated nuclear export of HSP70 mRNA. Regulates the expression of myeloid transcription factors CEBPA,CEBPB and GAB2 by enhancing the levels of phosphatidylinositol 3,4,5-trisphosphate. May be involved in thedifferentiation of granulocytes and adipocytes. Essential for hematopoietic primitive cell survival and plays anintegral role in monocytic development
Clone Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for THOC5 (see all 6) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for THOC5 (see all 5) OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 4): THOC5 (NM_001002878) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for THOC5 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat THOC5  |
In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for THOC5 |
Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table
THOC5 for ontologies About GeneDecksing
1 GenomeRNAi human phenotype for THOC5: Animal Models: Mouse knock-out Thoc5tm1.1Tate for THOC5 5 MGI mutant phenotypes (inferred from 2 alleles ) (MGI details for Thoc5):
THOC5 for phenotypes About GeneDecksing
|
Pathways & Interactions for THOC5 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
| Unified GeneCards pathways  About this table  See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | RNA transport | |
Pathway sources See GeneCards unified pathways Show all pathways
1
Kegg Pathway (Kegg details for THOC5):
THOC5 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for THOC5
STRING Interaction
Network Preview (showing 5 interactants - click image to see 18)
 5/20 Interacting proteins for THOC5 (Q137692, 3 ENSP000003809694) via UniProtKB, MINT, STRING, and/or I2D (see all 20)About this table
Gene Ontology (GO): 5/7 biological process terms (GO ID links to tree view) (see all 7): About this table
THOC5 for ontologies About GeneDecksing
|
Drugs & Compounds for THOC5 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
Browse Tocris compounds for THOC5 Search CenterWatch for drugs/clinical trials and news about THOC5 
|
Transcripts for THOC5 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank, RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
) About This Section
| REFSEQ mRNAs for THOC5 gene (4 alternative transcripts): NM_001002877.1 NM_001002878.1 NM_001002879.1 NM_003678.4 Unigene Cluster for THOC5: THO complex 5 Hs.75361 [show with all ESTs]Unigene Representative Sequence: AB02320017 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000490103(uc003afq.3 uc003afu.3) ENST00000442555(uc003afv.1) ENST00000472164 ENST00000358079 ENST00000397873 ENST00000484924 ENST00000443089 ENST00000492707 ENST00000488052 ENST00000475187(uc003afw.1) ENST00000440771 ENST00000455450 ENST00000428374 ENST00000414902 ENST00000418021 ENST00000397872(uc003afr.3 uc003aft.3) ENST00000397871(uc003afs.3)
Clone Products: |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for THOC5 (see all 6) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for THOC5 (see all 5) OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 4): THOC5 (NM_001002878) | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for THOC5 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat THOC5  |
Additional cDNA sequence: AB023200.1 AJ006069.1 AK025385.1 AK098709.1 AK122673.1 AK225169.1 AK225752.1 BC003615.2 CR456542.1 20 DOTS entries: DT.40286962 DT.412150 DT.100758416 DT.100803549 DT.100815593 DT.120651437 DT.120651427 DT.100687777 DT.95303703 DT.92438295 DT.120651401 DT.97848428 DT.95303704 DT.100815587 DT.100815589 DT.120651434 DT.120651343 DT.120651429 DT.40209926 DT.92069719 24/761 AceView cDNA sequences (see all 761): CF140265 AI460012 BU539274 AI349460 BQ649847 Z40980 AW197176 AW340285 Z98516 F11739 CR598880 CB159722 AI538702 BC006473 BQ004568 BM457603 AV645951 CR623297 BU191992 BF968938 BQ185814 BM675020 BM705613 BQ440046 GeneLoc Exon Structure
5 Alternative Splicing Database (ASD) splice patterns (SP) for THOC5 About this scheme
| ExUns: | 1a | · | 1b | ^ | 2a | · | 2b | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11 | ^ | 12 | ^ | 13 | ^ | 14 | ^ | 15 | ^ | 16 | ^ | 17 | ^ | 18 | ^ | 19 | ^ | 20 | ^ | 21 | ^ | 22 | ^ | 23 | ^ | 24a | · | |
| SP1: | |   | |   | - |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP2: | |   | |   | - |   | - |   | - |   | |   | |   | |   | |   | |   | |   | |   | - |   | |   | |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP3: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | - |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP4: | |   | |   | |   | |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP5: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   |
| ExUns: | 24b | |
| SP1: | |   | |
| SP2: | |   | |
| SP3: | |   | |
| SP4: | |   | |
| SP5: | |   |
ECgene alternative splicing isoforms for THOC5
|
Expression for THOC5 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| THOC5 expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this imageBioGPS CGAP TAG: TGACTCTTGA
About this image See THOC5 Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for THOC5
SOURCE GeneReport for Unigene cluster: Hs.75361 UniProtKB/Swiss-Prot: THOC5_HUMAN, Q13769Tissue specificity: Ubiquitously expressed SABiosciences Custom PCR Arrays for THOC5
Primer Products: |  | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for THOC5 Browse OriGene validated miRNA SYBR primer pairs
| |  | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat THOC5 | |  | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat THOC5 | |  | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat THOC5 | In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for THOC5 |
Orthologs for THOC5 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for THOC5 gene from 9/26 species (see all 26) About this table
ENSEMBL Gene Tree for THOC5 (if available) TreeFam Gene Tree for THOC5 (if available)  |
Paralogs for THOC5 gene(Paralogs according to
1HomoloGene, 2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68) About This Section
| -- |
Genomic Variants for THOC5 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical significance | Chr 22 pos | Sequence | # | AA Chg | Type | More | # | Allele freq | Pop | Total sample | More |
|---|
HapMap Linkage Disequilibrium report for THOC5 (29901868 - 29951205 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV) variations for THOC5: --  | SABiosciences Cancer Mutation PCR Assays |
|  | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing THOC5 |
|
Disorders
/ Diseases for THOC5 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
THOC5 for disorders About GeneDecksing
OMIM gene information: 612733
OMIM disorders: --
8 diseases for THOC5: About MalaCardsmeningioma ataxia telangiectasia kaposi's sarcoma neurofibromatosis conjunctivitis ataxia sarcoma breast cancer Export disorders for THOC5 gene to outside databases
|
Publications for THOC5 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for THOC5 gene, integrated from 9 sources (see all 36): (articles sorted by number of sources associating them with THOC5) | |  | Utopia: connect your pdf to the dynamic world of online information |
- THOC5 spliceosome protein: a target for leukaemogenic tyrosine kinases that affects inositol lipid turnover. (PubMed id 18373705)1, 2, 3 Pierce A....Whetton A.D. (2008)
- Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 10231032)1, 2, 3 Nagase T.... Ohara O. (1999)
- Cloning of a novel, anonymous gene from a megabase-range YAC and cosmid contig in the neurofibromatosis type 2/meningioma region on human chromosome 22q12. (PubMed id 8242058)1, 2, 3 Xie Y.G.... Dumanski J.P. (1993)
- Nuclear localization of the pre-mRNA associating protein THOC7 depends upon its direct interaction with Fms tyrosine kinase interacting protein (FMIP). (PubMed id 19059247)1, 2, 9 El Bounkari O.... Tamura T. (2009)
- Adaptor Aly and co-adaptor Thoc5 function in the Tap-p15-mediated nuclear export of HSP70 mRNA. (PubMed id 19165146)1, 2 Katahira J.... Yoneda Y. (2009)
- THOC5 couples M-CSF receptor signaling to transcription factor expression. (PubMed id 19015024)1, 3 Carney L....Whetton A.D. (2009)
- Recruitment of the complete hTREX complex is required for Kaposi's sarcoma-associated herpesvirus intronless mRNA nuclear export and virus replication. (PubMed id 18974867)1, 2 Boyne J.R.... Whitehouse A. (2008)
- Human mRNA export machinery recruited to the 5' end of mRNA. (PubMed id 17190602)1, 2 Cheng H.... Reed R. (2006)
- Recruitment of the human TREX complex to mRNA during splicing. (PubMed id 15998806)1, 2 Masuda S.... Reed R. (2005)
- Linking transcriptional elongation and messenger RNA export to metastatic breast cancers. (PubMed id 15833825)1, 2 Guo S.... Shiekhattar R. (2005)
|
External Searches for THOC5 gene
(in PubMed,
OMIM, and NCBI Bookshelf) About This Section
|
|
Genome Databases showing THOC5 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing THOC5 gene
(According to HUGE)
About This Section
| |
Specialized Databases showing THOC5 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL, Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot) About This Section
|
|
About This Section
| Patent Information for THOC5 gene: Search GeneIP for patents involving THOC5
GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products for THOC5 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences), In Situ Hybridization Assays from Advanced Cell Diagnostics About This Section
|
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 | |
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| | | | OriGene Antibodies for THOC5 | | OriGene shRNA RFP for THOC5 | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for THOC5 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for THOC5 | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | OriGene siRNA for THOC5 | | OriGene 3'-UTR Clone for THOC5 | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for THOC5 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for THOC5 | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | OriGene Custom Antibody Services for THOC5 | | OriGene Custom Protein Services for THOC5 | | OriGene Custom Immunoassay Development | | |
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| | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat THOC5 | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing THOC5 | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat THOC5 | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat THOC5 | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat THOC5 | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat THOC5 |
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| | | Search Tocris compounds for THOC5 |
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 | | THOC5 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for THOC5 |
|  |  |  | | | Search ThermoFisher Antibodies for THOC5 |
| | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat THOC5 |
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