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THG1L Gene

protein-coding   GIFtS: 52
GCID: GC05P157159

TRNA-Histidine Guanylyltransferase 1-Like (S. Cerevisiae)

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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
TRNA-Histidine Guanylyltransferase 1-Like (S. Cerevisiae)1 2     Probable TRNA(His) Guanylyltransferase2
Interphase Cytoplasmic Foci Protein 451 2 3     EC 2.7.7.793
ICF452 3     TRNA-Histidine Guanylyltransferase3
IHG-12     EC 2.7.78
Induced By High Glucose-12     EC 2.7.7.68

External Ids:    HGNC: 260531   Entrez Gene: 549742   Ensembl: ENSG000001132727   UniProtKB: Q9NWX63   

Export aliases for THG1L gene to outside databases

Previous GC identifers: GC05P157090 GC05P152246


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for THG1L Gene:
THG1L (tRNA-histidine guanylyltransferase 1-like (S. cerevisiae)) is a protein-coding gene. GO annotations related to this gene include magnesium ion binding and identical protein binding.

UniProtKB/Swiss-Prot: THG1_HUMAN, Q9NWX6
Function: Adds a GMP to the 5'-end of tRNA(His) after transcription and RNase P cleavage. This step is essential
for proper recognition of the tRNA and for the fidelity of protein synthesis

Gene Wiki entry for THG1L Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000005.9  NT_023133.14  NC_018916.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the THG1L gene promoter:
         TBP   p53   Arnt   RORalpha2   CREB   PPAR-gamma1   deltaCREB   PPAR-gamma2   TGIF   RSRFC4   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidTHG1L promoter sequence
   Search Chromatin IP Primers for THG1L

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat THG1L


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 5q33.3   Ensembl cytogenetic band:  5q33.3   HGNC cytogenetic band: 5q33.3

THG1L Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
THG1L gene location

GeneLoc information about chromosome 5         GeneLoc Exon Structure

GeneLoc location for GC05P157159:  view genomic region     (about GC identifiers)

Start:
157,158,205 bp from pter      End:
157,168,456 bp from pter
Size:
10,252 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: THG1_HUMAN, Q9NWX6 (See protein sequence)
Recommended Name: Probable tRNA(His) guanylyltransferase  
Size: 298 amino acids; 34831 Da
Cofactor: Binds 2 magnesium ions per subunit
Subunit: Homotetramer
Sequence caution: Sequence=AAH01523.2; Type=Erroneous initiation; Note=Translation N-terminally extended;
Sequence=AAH01852.2; Type=Erroneous initiation; Note=Translation N-terminally extended;
4 PDB 3D structures from and Proteopedia for THG1L:
3OTB (3D)        3OTC (3D)        3OTD (3D)        3OTE (3D)    
Secondary accessions: D3DQJ5 Q53G12 Q7L5R3 Q9H0S2

Explore the universe of human proteins at neXtProt for THG1L: NX_Q9NWX6

Explore proteomics data for THG1L at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus
  • Selected DME Specific Peptides for THG1L (Q9NWX6) (see all 5)
     KDYLSWR  TLAADKN  QQSGLTP  ADKNEILF 


    See THG1L Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_060342.2  
    ENSEMBL proteins: 
     ENSP00000231198   ENSP00000428387   ENSP00000431090  

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    3 InterPro protein domains:
     IPR024956 tRNAHis_GuaTrfase_cat
     IPR025845 Thg1_C_dom
     IPR007537 tRNAHis_GuaTrfase_Thg1

    Graphical View of Domain Structure for InterPro Entry Q9NWX6

    ProtoNet protein and cluster: Q9NWX6

    UniProtKB/Swiss-Prot: THG1_HUMAN, Q9NWX6
    Similarity: Belongs to the tRNA(His) guanylyltransferase family


    Find genes that share domains with THG1L           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: THG1_HUMAN, Q9NWX6
    Function: Adds a GMP to the 5'-end of tRNA(His) after transcription and RNase P cleavage. This step is essential
    for proper recognition of the tRNA and for the fidelity of protein synthesis
    Catalytic activity: p-tRNA(His) + ATP + GTP = pppG-P-tRNA(His) + AMP + diphosphate

         Enzyme Numbers (IUBMB): EC 2.7.7.62 EC 2.7.72 EC 2.7.7.791

         Gene Ontology (GO): Selected molecular function terms (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000049tRNA binding TAS--
    GO:0000287magnesium ion binding IDA--
    GO:0005524ATP binding IDA--
    GO:0005525GTP binding IDA--
    GO:0008193tRNA guanylyltransferase activity ISS--
         
    Find genes that share ontologies with THG1L           About GenesLikeMe


    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for THG1L

    miRNA
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    miRTarBase miRNAs that target THG1L:
    hsa-mir-615-3p (MIRT039970)

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    2 qRT-PCR Assays for microRNAs that regulate THG1L:
    hsa-miR-3163 hsa-miR-340
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    THG1_HUMAN, Q9NWX6: Cytoplasm. Note=Found near the nuclear membrane
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    mitochondrion4
    cytosol2
    endoplasmic reticulum1
    nucleus1
    peroxisome1

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005737cytoplasm ISS--
    GO:0005739mitochondrion IDA--

    Find genes that share ontologies with THG1L           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for THG1L
    Interactions:

        Search GeneGlobe Interaction Network for THG1L

    STRING Interaction Network Preview (showing 5 interactants - click image to see 10)

    Selected Interacting proteins for THG1L (Q9NWX62, 3 ENSP000002311984) via UniProtKB, MINT, STRING, and/or I2D (see all 45)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ELMOD1Q8N3362, 3, ENSP000002658404MINT-66859 I2D: score=5 STRING: ENSP00000265840
    HARSP120813, ENSP000003046684I2D: score=1 STRING: ENSP00000304668
    UBCP0CG483, ENSP000003448184I2D: score=1 STRING: ENSP00000344818
    EIF2B2P497703I2D: score=6 
    KPNA6O606843I2D: score=6 
    About this table

    Gene Ontology (GO): 3 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006400tRNA modification ISS--
    GO:0008033tRNA processing IDA--
    GO:0051289protein homotetramerization IPI--

    Find genes that share ontologies with THG1L           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for THG1L (THG1)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for THG1L gene: 
    NM_017872.3  

    Unigene Cluster for THG1L:

    TRNA-histidine guanylyltransferase 1-like (S. cerevisiae)
    Hs.353090  [show with all ESTs]
    Unigene Representative Sequence: AK223119
    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000231198(uc003lxd.3 uc011ddu.2) ENST00000521655 ENST00000523575

    miRNA
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    2 qRT-PCR Assays for microRNAs that regulate THG1L:
    hsa-miR-3163 hsa-miR-340
    SwitchGear 3'UTR luciferase reporter plasmidTHG1L 3' UTR sequence
    Inhib. RNA
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    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat THG1L
      QuantiTect SYBR Green Assays in human, mouse, rat THG1L
      QuantiFast Probe-based Assays in human, mouse, rat THG1L

    Additional mRNA sequence: 

    AF086486.1 AF110136.1 AK000553.1 AK023355.1 AK223119.1 AK304590.1 AL136669.1 AY463216.1 
    BC001523.2 BC001852.2 BC023521.2 CR533503.1 

    7 DOTS entries:

    DT.452261  DT.100042208  DT.97844022  DT.95300405  DT.97844023  DT.87046144  DT.120862122 

    Selected AceView cDNA sequences (see all 115):

    BC001523 BE302209 BQ687021 CR533503 BG682171 BC023521 BQ068560 N54163 
    BM848303 AL530910 BC001852 AY463216 CR626757 BQ188252 AI572790 BM987297 
    BM846072 AU134061 BM762289 CB122531 AA308526 BE893256 BM763974 BE019441 

    GeneLoc Exon Structure

    4 Alternative Splicing Database (ASD) splice patterns (SP) for THG1L    About this scheme

    ExUns: 1a · 1b · 1c · 1d ^ 2a · 2b ^ 3a · 3b · 3c ^ 4 ^ 5 ^ 6a · 6b
    SP1:                                                                              
    SP2:                                      -     -                                 
    SP3:                                -     -                                       
    SP4:                                                                              


    ECgene alternative splicing isoforms for THG1L

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    THG1L expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GTTCCTTTGG
    THG1L Expression
    About this image


    THG1L expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 3) fully expand
     
     Trophoblast (Extraembryonic Tissues)
             Trophoblast Cells Trophoblast
     
     Testis (Reproductive System)
             Leydig Cells Testis Interstitium
     
     Brain (Nervous System)
             Cerebellum
    THG1L Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    THG1L Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.353090

    UniProtKB/Swiss-Prot: THG1_HUMAN, Q9NWX6
    Tissue specificity: Expressed in many tissues

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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of eukaryotes.

    Orthologs for THG1L gene from Selected species (see all 23)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Thg1l1 , 5 tRNA-histidine guanylyltransferase 1-like (S. cerevisiae)1, 5 83.45(n)1
    82.21(a)1
      11 (27.47 cM)5
    666281  NM_001080969.21  NP_001074438.11 
     459468435 
    chicken
    (Gallus gallus)
    Aves THG1L1 tRNA-histidine guanylyltransferase 1-like (S. cerevisiae) 79.06(n)
    84.39(a)
      416242  NM_001030616.1  NP_001025787.1 
    lizard
    (Anolis carolinensis)
    Reptilia THG1L6
    tRNA-histidine guanylyltransferase 1-like (S. cere...
    72(a)
    1 ↔ 1
    GL343205.1(2839547-2849523)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.102722 Xenopus laevis transcribed sequence with moderate similarity more 78.23(n)    BU901293.1 
    zebrafish
    (Danio rerio)
    Actinopterygii Dr.168652 Transcribed sequence with weak similarity to protein more 75.48(n)    BM081120.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta l(2)35Bc1 lethal (2) 35Bc 59.08(n)
    58.94(a)
      34876  NM_001201886.1  NP_001188815.1 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes THG1(YGR024C)4
    THG11
    tRNAHis guanylyltransferase, adds a guanosine residue more4
    THG11
    55.19(n)1
    52.83(a)1
      7(532596-531883)4
    8529081, 4  NP_011538.31  NP_011538.14 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT2G315801 AT2G31580 55.51(n)
    47.01(a)
      817716  NM_128715.2  NP_565727.2 
    rice
    (Oryza sativa)
    Liliopsida Os05g05355001 Os05g0535500 57.66(n)
    49.81(a)
      4339440  NM_001062691.1  NP_001056156.1 


    ENSEMBL Gene Tree for THG1L (if available)
    TreeFam Gene Tree for THG1L (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section

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      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for THG1L (see all 289)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 5 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs358242601,2
    F--157156374(+) CCTTTC/TACTAA 1 -- us2k11Minor allele frequency- T:0.00NA 2
    rs1119747621,2
    C--157156438(+) ATTTAC/TGTAAA 1 -- us2k12Minor allele frequency- T:0.33CSA 3
    rs562019251,2
    C,F--157156515(+) CCAAAG/ACCAAT 1 -- us2k11Minor allele frequency- A:0.50WA 2
    rs1913252611,2
    --157156645(+) GCACCC/TGTAGT 1 -- us2k10--------
    rs562549421,2
    C,F--157156671(+) GGGAGG/ATGGGA 1 -- us2k11Minor allele frequency- A:0.50WA 2
    rs744257511,2
    C,F--157156764(+) TGTCTC/TGAAAA 1 -- us2k14Minor allele frequency- T:0.11WA NA EA 242
    rs756696161,2
    C,F--157156787(+) AAAAAT/CAAAAA 1 -- us2k11Minor allele frequency- C:0.08EA 120
    rs561173451,2
    C,F--157156879(+) CTCCTG/AGTCAG 1 -- us2k13Minor allele frequency- A:0.19NA EA 242
    rs1506897301,2
    --157156916(+) AAAGGC/TGAGGA 1 -- us2k10--------
    rs1394014141,2
    --157157080(+) TCCCAA/GTTCCT 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for THG1L (157158205 - 157168456 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for THG1L:    About this table    
    Variant IDTypeSubtypePubMed ID
    dgv1868e1CNV Complex17122850

    Site Specific Mutation Identification with PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    Find genes that share disorders with THG1L           About GenesLikeMe

    Genetic Association Database (GAD): THG1L
    Human Genome Epidemiology (HuGE) Navigator: THG1L (1 document)

    Export disorders for THG1L gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for THG1L gene, integrated from 10 sources (see all 22):
    (articles sorted by number of sources associating them with THG1L)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PubMed id 11230166)1, 2, 3 Wiemann S.... Poustka A. (Genome Res. 2001)
    2. Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression. (PubMed id 20877624)1, 4 Hendrickson S.L....O'Brien S.J. (PLoS ONE 2010)
    3. Identification and characterization of a novel cytoplasm protein ICF45 that is involved in cell cycle regulation. (PubMed id 15459185)1, 2 Guo D.... He D. (J. Biol. Chem. 2004)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    5. Why do cellular proteins linked to K63-polyubiquitin chains not associate with proteasomes? (PubMed id 23314748)1 Nathan J.A....Goldberg A.L. (EMBO J. 2013)
    6. Structural studies of a bacterial tRNA(HIS) guanylyltransferase (Thg1)-like protein, with nucleotide in the activation and nucleotidyl transfer sites. (PubMed id 23844012)1 Hyde S.J....DoubliAc S. (PLoS ONE 2013)
    7. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (Cell 2012)
    8. A high-throughput approach for measuring temporal changes in the interactome. (PubMed id 22863883)1 Kristensen A.R....Foster L.J. (Nat. Methods 2012)
    9. N-terminal acetylome analyses and functional insights of the N- terminal acetyltransferase NatB. (PubMed id 22814378)2 Van Damme P....Aldabe R. (Proc. Natl. Acad. Sci. U.S.A. 2012)
    10. A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (amp 2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 54974 HGNC: 26053 AceView: ICF45 Ensembl:ENSG00000113272 euGenes: HUgn54974
    ECgene: THG1L H-InvDB: THG1L

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for THG1L Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for THG1L gene:
    Search GeneIP for patents involving THG1L

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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