THEMIS Gene
protein-coding GIFtS: 49
GCID: GC06M128029
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thymocyte selection associated(Previous names: chromosome 6 open reading frame 207, chromosome 6 open...)
(Previous symbols: C6orf207, C6orf190, TSEPA)
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Aliases
for THEMIS gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Thymocyte Selection Associated1 2 | | SPOT2 5 | | C6orf1901 2 3 | | FLJ405841 | | C6orf2071 2 3 | | Chromosome 6 Open Reading Frame 1901 | | TSEPA1 2 | | Chromosome 6 Open Reading Frame 2071 | | BA325O24.31 | | GRB2-Associated Protein2 | | BA325O24.41 | | Protein THEMIS2 | | Thymocyte Selection Pathway Associated1 2 | | Signaling Phosphoprotein Specific For T Cells2 | | Thymocyte-Expressed Molecule Involved In Selection2 3 | | Thymocyte Expressed Molecule Involved In Selection2 | | GASP2 5 | | C6ORF1905 |
Export aliases for THEMIS gene to outside databasesPrevious GC identifer: GC06M125605 |
Summaries
for THEMIS gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for THEMIS:
This gene encodes a protein that plays a regulatory role in both positive and negative T-cell selection during latethymocyte development. The protein functions through T-cell antigen receptor signaling, and is necessary for properlineage commitment and maturation of T-cells. Alternative splicing results in multiple transcript variants. (providedby RefSeq, Sep 2009)
UniProtKB/Swiss-Prot: THMS1_HUMAN, Q8N1K5Function: Plays a central role in late thymocyte development by controlling both positive and negative T-cellselection. Required to sustain and/or integrate signals required for proper lineage commitment and maturation ofT-cells. Regulates T-cell development through T-cell antigen receptor (TCR) signaling and in particular through theregulation of calcium influx and phosphorylation of Erk (By similarity)
Gene Wiki entry for THEMIS (Protein THEMIS)
|
Genomic Views
for THEMIS gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000006.11 NC_018917.1 NT_025741.15
Regulatory elements:
 Search SABiosciences Regulatory transcription factor binding sites for THEMIS
Other transcription factors
Search SABiosciences Chromatin IP Primers for THEMIS
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat THEMIS |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 6q22.33 Ensembl cytogenetic band: 6q22.33 HGNC cytogenetic band: 6q22.33THEMIS Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 6 GeneLoc Exon Structure GeneLoc location for GC06M128029: view genomic region
(about GC identifiers)
Start:
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128,029,217 bp from pter |
End:
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128,239,776 bp from pter |
Size:
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210,560 bases |
Orientation:
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minus strand |
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Proteins
for THEMIS gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: THMS1_HUMAN, Q8N1K5 (See
protein sequence)Recommended Name: Protein THEMIS Size: 641 amino acids; 73452 Da
Subunit: Interacts with PLCG1, ITK, GRB2, and LAT (By similarity)
Subcellular location: Cytoplasm (By similarity). Nucleus (By similarity)
Sequence caution: Sequence=BAC05194.1; Type=Miscellaneous discrepancy; Note=Contaminating sequence. Potential poly-Asequence; Sequence=BAG52943.1; Type=Erroneous initiation; Note=Translation N-terminally extended; Sequence=CAI13397.1;Type=Erroneous gene model prediction; Sequence=CAI17111.1; Type=Erroneous gene model prediction;
Secondary accessions: A1L4F0 A8K7N1 B3KT31 B3KW32 B3KY07 Q5T3C4 Q5T3C5 Q6MZT7Alternative splicing: 3 isoforms: Q8N1K5-1 Q8N1K5-2 Q8N1K5-3 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for THEMIS: NX_Q8N1K5
Post-translational modifications:
Phosphorylated on Tyr residues quickly after TCR stimulation (By similarity)1
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q8N1K5
THEMIS Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (3 alternative transcripts):
NP_001010923.1 NP_001158157.1 NP_001158159.1
ENSEMBL proteins: ENSP00000357233 ENSP00000387740 ENSP00000439594 ENSP00000357231 ENSP00000439863
Human Recombinant Protein Products:
Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view): About this table
THEMIS for ontologies About GeneDecksing
THEMIS Antibody Products:
Assay Products for THEMIS: |
Protein
Domains /
Families
for THEMIS gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
THEMIS for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry Q8N1K5ProtoNet protein and cluster: Q8N1K5 UniProtKB/Swiss-Prot: THMS1_HUMAN, Q8N1K5Similarity: Belongs to the themis family |
Function
for THEMIS gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: THMS1_HUMAN, Q8N1K5Function: Plays a central role in late thymocyte development by controlling both positive and negative T-cellselection. Required to sustain and/or integrate signals required for proper lineage commitment and maturation ofT-cells. Regulates T-cell development through T-cell antigen receptor (TCR) signaling and in particular through theregulation of calcium influx and phosphorylation of Erk (By similarity)
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for THEMIS (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for THEMIS (see all 3)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 3): THEMIS (NM_001010923) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for THEMIS | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat THEMIS |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for THEMIS |
Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005515 | protein binding |
-- | -- |
THEMIS for ontologies About GeneDecksing
Animal Models:
Mouse knock-outs for THEMIS: Themistm1Gasc Themistm1Lov
3 MGI mutant phenotypes (inferred from 6 alleles ) (MGI details for Themis):
THEMIS for phenotypes About GeneDecksing
|
Pathways & Interactions
for THEMIS gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Lymphocyte Signaling | |
Pathway sources
See GeneCards unified pathways
Show all pathways
1 
Cell Signaling Technology (CST) Pathway for THEMIS
THEMIS for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for THEMIS
STRING Interaction
Network Preview (showing 1 interactants - click image to see more details)
1 Interacting protein for THEMIS (ENSP000003572314) via UniProtKB, MINT, STRING, and/or I2DAbout this table
Gene Ontology (GO): 3 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0043368 | positive T cell selection |
ISS | -- | | GO:0043383 | negative T cell selection |
ISS | -- | | GO:0050852 | T cell receptor signaling pathway |
ISS | -- |
THEMIS for ontologies About GeneDecksing
|
Drugs & Compounds
for THEMIS gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for THEMIS
Search CenterWatch for drugs/clinical trials and news about THEMIS / THMS1
|
Transcripts
for THEMIS gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for THEMIS gene (3 alternative transcripts): NM_001010923.2 NM_001164685.1 NM_001164687.1 Unigene Cluster for THEMIS: Thymocyte selection associated Hs.661756 [show with all ESTs]Unigene Representative Sequence: NM_0011646855 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000368250 ENST00000434358 ENST00000543064(uc011ebt.2) ENST00000368248(uc021zfa.1)
ENST00000537166(uc010kfa.3 uc010kfb.3)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for THEMIS (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for THEMIS (see all 3)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 3): THEMIS (NM_001010923) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for THEMIS | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat THEMIS |
Additional cDNA sequence: AK094863.1 AK097903.1 AK124031.1 AK128377.1 AK292046.1 BC043608.1 BC130516.1 BC144034.1 BX640890.1 3 DOTS entries: DT.101978391 DT.40118847 DT.121368393 17 AceView cDNA sequences: BC043608 BX956657 AA347217 AK097903 AK128377 BM925778 AK124031 CD521591 BX640890 AK094863 AA347216 AA309802 CD695427 BF824839 CD704340 BF379806 BX427339
GeneLoc Exon Structure
4 Alternative Splicing Database (ASD) splice patterns (SP) for THEMIS About this scheme
| ExUns: | 1a | · | 1b | ^ | 2a | · | 2b | ^ | 3 | ^ | 4 | ^ | 5a | · | 5b | ^ | 6 | ^ | 7 | ^ | 8 |
|---|
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| SP1: | | | | | | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | - | | - | | | | | | | | | | | | |
| SP3: | | | | | | | | | - | | - | | | | | | | | | | | | |
| SP4: | | | - | | | | | | - | | - | | | | | | | | | | | |
ECgene alternative splicing isoforms for THEMIS
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Expression
for THEMIS gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| THEMIS expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CTCACCTATT
About this image
See THEMIS Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for THEMIS
SOURCE GeneReport for Unigene cluster: Hs.661756
SABiosciences Custom PCR Arrays for THEMIS
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for THEMIS
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat THEMIS | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat THEMIS | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat THEMIS | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for THEMIS |
Orthologs
for THEMIS gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for THEMIS gene from 4/9 species (see all 9) About this table
ENSEMBL Gene Tree for THEMIS (if available)
TreeFam Gene Tree for THEMIS (if available) |
Paralogs
for THEMIS gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for THEMIS gene
- THEMIS22
5 SIMAP similar genes for THEMIS using alignment to 2 protein entries: THMS1_HUMAN (see all proteins):AURA2 FAM3A NF2 ZNF564 THEMIS2
THEMIS for paralogs About GeneDecksing
1 Pseudogenes.org Pseudogene for THEMIS
PGOHUM00000234982
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Genomic Variants
for THEMIS gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 6 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for THEMIS (128029217 - 128239776 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 4 variations for THEMIS
2 CNVs: 94007 0091
2 Indels: 60620 59293 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing THEMIS |
|
Disorders
/ Diseases
for THEMIS gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
THEMIS for disorders About GeneDecksing
OMIM gene information: 613607
OMIM disorders: --
2  diseases for THEMIS: About MalaCardsceliac disease breast cancer
Human Genome Epidemiology (HuGE) Navigator: THEMIS (5 documents)
Export disorders for THEMIS gene to outside databases
|
Publications
for THEMIS gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for THEMIS gene, integrated from 9 sources (see all 25):
(articles sorted by number of sources associating them with THEMIS) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Themis is a member of a new metazoan gene family and is required for the completion of thymocyte positive selection. (PubMed id 19597497)1, 3 Johnson A.L....Schwartz R.H. (2009)
- Themis, a T cell-specific protein important for late thymocyte development. (PubMed id 19597498)1, 3 Lesourne R....Love P.E. (2009)
- Themis controls thymocyte selection through regulatio n of T cell antigen receptor-mediated signaling. (PubMed id 19597499)1, 3 Fu G....Gascoigne N.R. (2009)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Exome sequencing identifies recurrent SPOP, FOXA1 and MED12 mutations in prostate cancer. (PubMed id 22610119)1 Barbieri C.E....Garraway L.A. (2012)
- Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (2012)
- Interchangeability of Themis1 and Themis2 in thymocyte development reveals two related proteins with conserved molecular function. (PubMed id 22732588)1 Lesourne R....Love P.E. (2012)
- Genome-wide analysis of polymorphisms associated with cytokine responses in smallpox vaccine recipients. (PubMed id 22610502)1 Kennedy R.B....Poland G.A. (2012)
- Genetic risk and a primary role for cell-mediated immu ne mechanisms in multiple sclerosis. (PubMed id 21833088)1 ....Compston A. (2011)
- T cell receptor (TCR)-induced tyrosine phosphorylatio n dynamics identifies THEMIS as a new TCR signalosome component. (PubMed id 21189249)1 Brockmeyer C....Salek M. (2011)
|
External Searches for THEMIS gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing THEMIS gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing THEMIS gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing THEMIS gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for THEMIS | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for THEMIS gene:
Search GeneIP for patents involving THEMIS
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for THEMIS gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | OriGene Antibodies for THEMIS | | OriGene shRNA RFP for THEMIS | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for THEMIS | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for THEMIS | | | OriGene Protein Over-expression Lysate for THEMIS | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for THEMIS | | OriGene 3'-UTR Clone for THEMIS | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for THEMIS | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for THEMIS | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for THEMIS | | OriGene Custom Protein Services for THEMIS | | | OriGene Custom Immunoassay Development | | |
| |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat THEMIS | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing THEMIS | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat THEMIS | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat THEMIS | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat THEMIS | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat THEMIS |
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 |  |  |  | |
| | Antibodies & Assays for THEMIS |
| | | | Search Tocris compounds for THEMIS |
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 | | | THEMIS Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for THEMIS |
|  |  |  | | | | Search ThermoFisher Antibodies for THEMIS |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat THEMIS |
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