External Ids for THBS3 Gene
The protein encoded by this gene belongs to the thrombospondin family. Thrombospondin family members are adhesive glycoproteins that mediate cell-to-cell and cell-to-matrix interactions. This protein forms a pentameric molecule linked by a single disulfide bond. This gene shares a common promoter with metaxin 1. Alternate splicing results in coding and non-coding transcript variants. [provided by RefSeq, Nov 2011]
GeneCards Summary for THBS3 Gene
THBS3 (Thrombospondin 3) is a Protein Coding gene. Diseases associated with THBS3 include pseudoachondroplasia. Among its related pathways are PI3K-Akt signaling pathway and Signaling by FGFR. GO annotations related to this gene include calcium ion binding and heparin binding. An important paralog of this gene is THBS4.
UniProtKB/Swiss-Prot for THBS3 Gene
Adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. Can bind to fibrinogen, fibronectin, laminin and type V collagen