Aliases for THBD Gene
Aliases for THBD Gene
External Ids for THBD Gene
- HGNC: 11784
- Entrez Gene: 7056
- Ensembl: ENSG00000178726
- OMIM: 188040
- UniProtKB: P07204
Previous GeneCards Identifiers for THBD Gene
- GC20M023014
- GC20M023021
- GC20M022974
Summaries for THBD Gene
-
The protein encoded by this intronless gene is an endothelial-specific type I membrane receptor that binds thrombin. This binding results in the activation of protein C, which degrades clotting factors Va and VIIIa and reduces the amount of thrombin generated. Mutations in this gene are a cause of thromboembolic disease, also known as inherited thrombophilia. [provided by RefSeq, Jul 2008]
GeneCards Summary for THBD Gene
THBD (Thrombomodulin) is a Protein Coding gene. Diseases associated with THBD include Thrombophilia Due To Thrombomodulin Defect and Hemolytic Uremic Syndrome, Atypical 6. Among its related pathways are Collagen biosynthesis and modifying enzymes and AGE-RAGE signaling pathway in diabetic complications. GO annotations related to this gene include calcium ion binding and transmembrane signaling receptor activity. An important paralog of this gene is CD93.
UniProtKB/Swiss-Prot for THBD Gene
-
Thrombomodulin is a specific endothelial cell receptor that forms a 1:1 stoichiometric complex with thrombin. This complex is responsible for the conversion of protein C to the activated protein C (protein Ca). Once evolved, protein Ca scissions the activated cofactors of the coagulation mechanism, factor Va and factor VIIIa, and thereby reduces the amount of thrombin generated.
No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for THBD Gene
Genomics for THBD Gene
Regulatory Elements for THBD Gene
Enhancers for THBD Gene
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around THBD on UCSC Golden Path with GeneCards custom track
- Transcription factor binding sites by QIAGEN in the THBD gene promoter:
Regulatory Element Products
Genomic Location for THBD Gene
- Chromosome:
- 20
- Start:
- 23,045,633 bp from pter
- End:
- 23,049,741 bp from pter
- Size:
- 4,109 bases
- Orientation:
- Minus strand
Genomic View for THBD Gene
Genes around THBD on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 20p11.21 by Ensembl
- 20p11.21 by Entrez Gene
- 20p11.21 by HGNC
THBD Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for THBD Gene
Proteins for THBD Gene
-
Protein details for THBD Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- P07204-TRBM_HUMAN
- Recommended name:
- Thrombomodulin
- Protein Accession:
- P07204
- Q8IV29
- Q9UC32
Protein attributes for THBD Gene
- Size:
- 575 amino acids
- Molecular mass:
- 60329 Da
- Quaternary structure:
-
- Interacts with ITGAL, ITGAM and ITGB2.
Protein Expression for THBD Gene
Post-translational modifications for THBD Gene
- N-glycosylated.
- The iron and 2-oxoglutarate dependent 3-hydroxylation of aspartate and asparagine is (R) stereospecific within EGF domains.
- Glycosylation at Asn 47, Asn 115, Asn 116, Asn 382, Asn 409, Ser 490, and Ser 492
- Modification sites at PhosphoSitePlus
Other Protein References for THBD Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- EMD Millipore Complete listing of Mono and Polychlonal Antibodies for THBD
- R&D Systems Antibodies for THBD (Thrombomodulin/BDCA-3)
-
Custom Antibody ServicesOriGene Antibodies for THBD
- Novus Biologicals Antibodies for THBD
-
Cloud-Clone Corp. Antibodies for THBD
- Invitrogen Antibodies for THBD
- antibodies-online Antibodies for THBD: See all 140
- GeneTex THBD antibody for THBD
-
St John's Laboratory Antibodies for THBD
Protein Products
- R&D Systems Proteins and Enzymes for THBD (Thrombomodulin/BDCA-3)
-
OriGene Purified Proteins for THBD
- Search Origene for MassSpec and Protein Over-expression Lysates for THBD
- Origene Custom Protein Services for THBD
- Novus Biologicals proteins for THBD
- Sino Biological Cell Lysates for THBD
- Sino Biological Recombinant Proteins for THBD
-
Cloud-Clone Corp. Proteins for THBD
- antibodies-online Proteins for THBD: See all 32
- Search antibodies-online for peptides
- GeneTex Proteins for THBD
Assay Products
- R&D Systems ELISAs and other biochemical assays for THBD (Thrombomodulin/BDCA-3)
-
Cloud-Clone Corp Assay Kits for THBD
- antibodies-online Kits for THBD: See all 77
No data available for DME Specific Peptides for THBD Gene
Domains & Families for THBD Gene
Gene Families for THBD Gene
Protein Domains for THBD Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for THBD Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
P07204UniProtKB/Swiss-Prot:
TRBM_HUMAN :- Extracellular region (481-515) contains a binding side for alpha-L/beta-2 and alpha-M/beta-2 integrin.
- Domain:
-
- Extracellular region (481-515) contains a binding side for alpha-L/beta-2 and alpha-M/beta-2 integrin.
- Contains 1 C-type lectin domain.
- Contains 6 EGF-like domains.
Function for THBD Gene
Molecular function for THBD Gene
- GENATLAS Biochemistry:
- thrombomodulin coagulation factor complexing with thrombin,the complex activating PROC,with mutations in the promoter region putatively associated with a risk for arterial thrombosis and myocardial infarction
- UniProtKB/Swiss-Prot Function:
- Thrombomodulin is a specific endothelial cell receptor that forms a 1:1 stoichiometric complex with thrombin. This complex is responsible for the conversion of protein C to the activated protein C (protein Ca). Once evolved, protein Ca scissions the activated cofactors of the coagulation mechanism, factor Va and factor VIIIa, and thereby reduces the amount of thrombin generated.
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0004872 | receptor activity | TAS | 2822087 |
| GO:0004888 | transmembrane signaling receptor activity | IEA | -- |
| GO:0005509 | calcium ion binding | IEA | -- |
| GO:0005515 | protein binding | IPI | 14691232 |
Phenotypes for THBD Gene
- MGI mutant phenotypes for THBD:
-
inferred from 11 alleles
- cellular phenotype
- mortality/aging
- growth/size/body region phenotype
- nervous system phenotype
- homeostasis/metabolism phenotype
- normal phenotype
- respiratory system phenotype
- immune system phenotype
- cardiovascular system phenotype
- reproductive system phenotype
- liver/biliary system phenotype
- integument phenotype
- hematopoietic system phenotype
- digestive/alimentary phenotype
- embryo phenotype
- renal/urinary system phenotype
- GenomeRNAi human phenotypes for THBD:
-
- Increased vaccinia virus (VACV) infection
- Decreased viability in esophageal squamous lineage
- Increased transferrin (TF) endocytosis
- Negative genetic interaction between PTEN-/- and PTEN+/+
- Negative genetic interaction between PTTG1-/- and PTTG1+/+
- Increased cell number in S
- Synthetic lethal with vaccinia virus (VACV) infection
Animal Models for THBD Gene
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for THBD
-
-
ViGene Biosciences lentiviral particle packaged cDNA for THBD gene
-
ViGene Biosciences ready-to-package AAV shRNAs for THBD gene
- Search ViGene Biosciences for THBD
CRISPR Products
-
OriGene CRISPR knockouts for THBD
- GenScript: Design CRISPR guide RNA sequences for THBD
miRNA for THBD Gene
- miRTarBase miRNAs that target THBD
-
- hsa-mir-335-5p (MIRT017044)
- hsa-mir-215-5p (MIRT024294)
- hsa-mir-192-5p (MIRT026159)
- hsa-mir-3127-5p (MIRT636176)
- hsa-mir-2115-5p (MIRT636177)
- hsa-mir-6879-5p (MIRT636178)
- hsa-mir-7843-5p (MIRT636179)
- hsa-mir-6735-5p (MIRT636180)
- hsa-mir-4632-5p (MIRT636181)
- hsa-mir-4436b-3p (MIRT636182)
- hsa-mir-578 (MIRT639318)
- hsa-mir-4763-3p (MIRT639319)
- hsa-mir-1207-5p (MIRT639320)
- hsa-mir-6836-5p (MIRT639321)
- hsa-mir-6132 (MIRT639322)
miRNA Products
- Search ViGene Biosciences for THBD
Clone Products
- Sino Biological Human cDNA Clone for THBD
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for THBD
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for THBD
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- R&D Systems cDNA Clones for THBD (Thrombomodulin/BDCA-3)
Cell Line Products
-
Horizon Cell Lines for THBD
-
ViGene Biosciences adenoviral particle packaged cDNA for THBD gene
-
ViGene Biosciences lentiviral particle packaged cDNA for THBD gene
-
ViGene Biosciences ready-to-package AAV shRNAs for THBD gene
Flow Cytometry Products
No data available for Enzyme Numbers (IUBMB) , Transcription Factor Targets and HOMER Transcription for THBD Gene
Localization for THBD Gene
Subcellular locations from UniProtKB/Swiss-Prot for THBD Gene
- Membrane; Single-pass type I membrane protein.
| Compartment | Confidence |
|---|---|
| plasma membrane | 5 |
| extracellular | 4 |
| cytoskeleton | 2 |
| nucleus | 2 |
| cytosol | 2 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005615 | extracellular space | IEA | -- |
| GO:0005774 | vacuolar membrane | IEA | -- |
| GO:0005886 | plasma membrane | IEA,TAS | -- |
| GO:0005887 | integral component of plasma membrane | IEA | -- |
| GO:0009986 | cell surface | IDA | 17379830 |
Pathways & Interactions for THBD Gene
Pathways by source for THBD Gene
2 BioSystems pathways for THBD Gene
4 Reactome pathways for THBD Gene
2 KEGG pathways for THBD Gene
2 R&D Systems pathways for THBD Gene
3 Qiagen pathways for THBD Gene
Interacting Proteins for THBD Gene
Selected Interacting proteins:
ENSP00000366307
P07204-TRBM_HUMAN
for THBD Gene via
STRING
UniProtKB
IID
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0007165 | signal transduction | IEA | -- |
| GO:0007565 | female pregnancy | IEA | -- |
| GO:0007596 | blood coagulation | IEA,TAS | -- |
| GO:0007599 | hemostasis | IEA | -- |
| GO:0010165 | response to X-ray | IEA | -- |
No data available for SIGNOR curated interactions for THBD Gene
Drugs & Compounds for THBD Gene
| Name | Synonyms | Role | CAS Number | PubChem IDs | PubMed IDs |
|---|
Transcripts for THBD Gene
mRNA/cDNA for THBD Gene
- (1) REFSEQ mRNAs :
- (7) Additional mRNA sequences :
- (122) Selected AceView cDNA sequences:
- (1) Ensembl transcripts including schematic representations, and UCSC links where relevant :
CRISPR Products
-
OriGene CRISPR knockouts for THBD
- GenScript: Design CRISPR guide RNA sequences for THBD
miRNA Products
- Search ViGene Biosciences for THBD
Clone Products
- Sino Biological Human cDNA Clone for THBD
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for THBD
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for THBD
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- R&D Systems cDNA Clones for THBD (Thrombomodulin/BDCA-3)
Flow Cytometry Products
Expression for THBD Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Cartilage (Muscoskeletal System)
- Intervertebral Disc Nucleus Pulposus Cells Nucleus Pulposus
- Mesenchymal Condensate Cells Zeugopod
- Nucleus Pulposus
- Intervertebral Disc
-
Blood (Hematopoietic System)
- Granulocytes Peripheral Blood
- Monocytes Peripheral Blood
-
Lung (Respiratory System)
- Basal Cells Respiratory Bronchioles
- Trachea
-
Peripheral Nervous System (Nervous System)
- Pro-myelinating Schwann Cells Peripheral Nerve Domain
- Immature Schwann Cells Peripheral Nerve Domain
-
Skeletal Muscle (Muscoskeletal System)
- Muscle Progenitor Cells Mandibular Arch Muscles
- Muscle Progenitor Cells Hyoid Arch Muscles
- Bone (Muscoskeletal System)
- NULL (Uncategorized)
-
Epithelial Cells
- Basal Cells Respiratory Bronchioles
-
Hypoblast (Extraembryonic Tissues)
- Extraembryonic Endoderm Cells Extraembryonic Endoderm
-
Yolk Sac (Extraembryonic Tissues)
- Extraembryonic Endoderm Cells Extraembryonic Endoderm
-
Testis (Reproductive System)
- Testicular Interstitial Cells Testis Interstitium
-
Limb (Muscoskeletal System)
- Mesenchymal Condensate Cells Zeugopod
- Brain (Nervous System)
- Primitive Streak (Early Embryonic Tissues)
- Gut Tube (Gastrointestinal Tract)
- Umbilical Cord (Extraembryonic Tissues)
- Extraembryonic Tissues (Extraembryonic Tissues)
- Uncategorized
- Endothelium (Cardiovascular System)
This gene is overexpressed in Pancreas (55.9).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for THBD Gene
NURSA nuclear receptor signaling pathways regulating expression of THBD Gene:
THBDSOURCE GeneReport for Unigene cluster for THBD Gene:
Hs.2030mRNA Expression by UniProt/SwissProt for THBD Gene:
P07204-TRBM_HUMAN
Tissue specificity:
Endothelial cells are unique in synthesizing thrombomodulin.
Primer Products
-
OriGene qPCR primer pairs for THBD
-
OriGene qPCR primer pairs and template standards for THBD
No data available for mRNA differential expression in normal tissues and Protein tissue co-expression partners for THBD Gene
Orthologs for THBD Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | THBD 34 35 |
|
||
| dog (Canis familiaris) |
Mammalia | THBD 34 35 |
|
||
| cow (Bos Taurus) |
Mammalia | THBD 34 35 |
|
||
| mouse (Mus musculus) |
Mammalia | Thbd 34 16 35 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Thbd 34 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | THBD 35 |
|
OneToOne | |
| platypus (Ornithorhynchus anatinus) |
Mammalia | THBD 35 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | THBD 34 35 |
|
||
| tropical clawed frog (Silurana tropicalis) |
Amphibia | thbd 34 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | THBD 35 |
|
OneToOne |
- Species where no ortholog for THBD was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- lizard (Anolis carolinensis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
Paralogs for THBD Gene
Variants for THBD Gene
| SNP ID | Clin | Chr 20 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs121918667 | Hemolytic uremic syndrome atypical 6 (AHUS6) [MIM:612926], other | 23,049,347(-) | CTGCG(A/G)CGGAC | reference, missense | |
| rs1800576 | Hemolytic uremic syndrome atypical 6 (AHUS6) [MIM:612926], other | 23,049,378(-) | GCCCC(A/G)CGACC | reference, missense | |
| rs1800578 | Hemolytic uremic syndrome atypical 6 (AHUS6) [MIM:612926], other | 23,048,022(-) | GCGAG(C/T)CCCCG | reference, missense | |
| rs1800579 | Hemolytic uremic syndrome atypical 6 (AHUS6) [MIM:612926] | 23,048,003(-) | GACGC(C/T)CGGCT | reference, missense | |
| rs41348347 | Hemolytic uremic syndrome atypical 6 (AHUS6) [MIM:612926], Thrombophilia due to thrombomodulin defect (THPH12) [MIM:614486], Uncertain significance | 23,048,049(-) | AGGTG(G/T)ACGGT | reference, missense |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv2758789 | CNV | loss | 17122850 |
| nsv482065 | CNV | gain | 20164927 |
Residual Variation Intolerance Score:
78.4% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
5.10;
69.11% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for THBD Gene
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for THBD Gene
Disorders for THBD Gene
(83) MalaCards diseases for THBD Gene - From: OMIM, ClinVar, GeneTests, Orphanet, Swiss-Prot, DISEASES, Novoseek, and GeneCards
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| thrombophilia due to thrombomodulin defect |
|
|
| hemolytic uremic syndrome, atypical 6 |
|
|
| thbd-related atypical hemolytic-uremic syndrome |
|
|
| hemolytic uremic syndrome, atypical 1 |
|
|
| thrombophilia |
|
Search THBD in MalaCards
View complete list of genes associated with diseases
UniProtKB/Swiss-Prot
TRBM_HUMAN- Hemolytic uremic syndrome atypical 6 (AHUS6) [MIM:612926]: An atypical form of hemolytic uremic syndrome. It is a complex genetic disease characterized by microangiopathic hemolytic anemia, thrombocytopenia, renal failure and absence of episodes of enterocolitis and diarrhea. In contrast to typical hemolytic uremic syndrome, atypical forms have a poorer prognosis, with higher death rates and frequent progression to end-stage renal disease. {ECO:0000269 PubMed:19625716, ECO:0000269 PubMed:20513133}. Note=Disease susceptibility is associated with variations affecting the gene represented in this entry. Other genes may play a role in modifying the phenotype.
- Thrombophilia due to thrombomodulin defect (THPH12) [MIM:614486]: A hemostatic disorder characterized by a tendency to thrombosis. {ECO:0000269 PubMed:12139752, ECO:0000269 PubMed:7811989, ECO:0000269 PubMed:9198186}. Note=The disease may be caused by mutations affecting the gene represented in this entry. The role of thrombomodulin in thrombosis is controversial. It is likely that genetic or environmental risk factors in addition to THBD variation are involved in the pathogenesis of venous thrombosis.
Genatlas disease for THBD Gene
thrombosis,recurrent
Relevant External Links for THBD
Publications for THBD Gene
- Thrombomodulin mutations in atypical hemolytic-uremic syndrome. (PMID: 19625716) Delvaeye M. … Conway E.M. (N. Engl. J. Med. 2009) 3 4 22 46 64
- Thrombomodulin Ala455Val polymorphism and risk of coronary heart disease. (PMID: 11245641) Wu K.K. … Juneja H. (Circulation 2001) 3 4 22 46 64
- Mutations in alternative pathway complement proteins in American patients with atypical hemolytic uremic syndrome. (PMID: 20513133) Maga T.K. … Smith R.J.H. (Hum. Mutat. 2010) 3 4 46 64
- Thrombomodulin gene polymorphisms or haplotypes as potential risk factors for venous thromboembolism: a population-based case-control study. (PMID: 15842356) Heit J.A. … Melton L.J. (J. Thromb. Haemost. 2005) 3 22 46 64
- Genetic risk for restenosis after coronary balloon angioplasty. (PMID: 15135268) Horibe H. … Yokota M. (Atherosclerosis 2004) 3 22 46 64
Products for THBD Gene
- R&D Systems Antibodies for THBD (Thrombomodulin/BDCA-3)
- R&D Systems Proteins and Enzymes for THBD (Thrombomodulin/BDCA-3)
- R&D Systems ELISAs and other biochemical assays for THBD (Thrombomodulin/BDCA-3)
- R&D Systems cDNA Clones for THBD (Thrombomodulin/BDCA-3)
- Browse Primary Antibodies
- Browse Proteins and Enzymes
- Browse ELISAs
- Browse Activity Assays
- Browse cDNA Clones
- Browse Cell Culture Products
- Browse Cell Selection and Detection Kits
- Browse DNA Damage and Repair Kits
- Browse ELISpot/FluoroSpot Kits and Development Modules
- Browse Flow Cytometry Kits
- Browse Immunoprecipitation Assays
- Browse Luminex Assays
- Browse Peptides
- Browse Proteome Profiler Antibody Arrays
- Browse Small Molecules
- Custom Antibody ServicesOriGene Antibodies for THBD
- Custom Assay ServicesOriGene ELISA Kits for THBD
- OriGene Purified Proteins for THBD
- Search Origene for MassSpec and Protein Over-expression Lysates for THBD
- Origene Custom Protein Services for THBD
- Origene siRNA, mouse_rna, shRNA, rat_shrna, and RNAi products in human, mouse, rat for THBD
- Browse OriGene Inhibitory RNA Products For THBD
- OriGene qPCR primer pairs and template standards for THBD
- OriGene qPCR primer pairs for THBD
- OriGene CRISPR knockouts for THBD
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For THBD
- GenScript: Next-day shipping cDNA clones in your preferred vector
- GenScript Custom Purified and Recombinant Proteins Services for THBD
- GenScript Custom Assay Services for THBD
- GenScript Custom overexpressing Cell Line Services for THBD
- GenScript: Design CRISPR guide RNA sequences for THBD
- Design optimal peptide antigens
- CloneReady with Over 120,000 Genes
- Gene Synthesis: Any Gene in Any Vector
- Vector-based siRNA and miRNA, Ready for Transfection
- Gene Mutant Library, Variants up to 10^11
- Plasmid Preparation
- GenScript Custom Peptide Services for THBD
- Sino Biological Human cDNA Clone for THBD
- Sino Biological Cell Lysates for THBD
- Sino Biological Recombinant Proteins for THBD
- Sino Biological Antibodies
- Sino Biological ELISA Kits and Pair Sets
- Sino Biological Cell Lysates
- Sino Biological qPCR Primers
- Sino Biological CRO Services for Proteins, Antibodies and Genes
- Sino Biological Transfection Reagents
- Novus Biologicals Antibodies for THBD
- Novus Biologicals proteins for THBD
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- Cloud-Clone Corp. Antibodies for THBD
- Cloud-Clone Corp. Proteins for THBD
- Cloud-Clone Corp Assay Kits for THBD
- antibodies-online Antibodies for THBD: See all 140
- antibodies-online Kits for THBD: See all 77
- antibodies-online Proteins for THBD: See all 32
- Search antibodies-online for peptides
- GeneTex THBD antibody for THBD
- GeneTex Proteins for THBD
- ViGene Biosciences adenoviral particle packaged cDNA for THBD gene
- ViGene Biosciences lentiviral particle packaged cDNA for THBD gene
- ViGene Biosciences ready-to-package AAV shRNAs for THBD gene
- Search ViGene Biosciences for THBD
- Horizon Cell Lines for THBD
- Cyagen custom Knockout/knockin (KOKI) mouse models for THBD
- VectorBuilder custom plasmid, inducible vectors for THBD
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for THBD
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for THBD Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
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