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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

THAP4 Gene

protein-coding   GIFtS: 49
GCID: GC02M242543

THAP Domain Containing 4

  See related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
THAP Domain Containing 41 2
PP2382
THAP Domain-Containing Protein 42

External Ids:    HGNC: 231871   Entrez Gene: 510782   Ensembl: ENSG000001769467   OMIM: 6125335   UniProtKB: Q8WY913   

Export aliases for THAP4 gene to outside databases

Previous GC identifers: GC02M242844 GC02M242243 GC02M234277


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for THAP4 Gene: 
THAP4 (THAP domain containing 4) is a protein-coding gene. Diseases associated with THAP4 include tuberculosis. GO annotations related to this gene include DNA binding and metal ion binding.

Gene Wiki entry for THAP4 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000002.11  NT_005416.13  NC_018913.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the THAP4 gene promoter:
         Tal-1   Pax-6   E47   YY1   GATA-1   MEF-2A   E2F-1   E2F   HOXA5   aMEF-2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidTHAP4 promoter sequence
   Search SABiosciences Chromatin IP Primers for THAP4

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat THAP4


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 2q37.3   Ensembl cytogenetic band:  2q37.3   HGNC cytogenetic band: 2q37.3

THAP4 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
THAP4 gene location

GeneLoc information about chromosome 2         GeneLoc Exon Structure

GeneLoc location for GC02M242543:  view genomic region     (about GC identifiers)

Start:
242,523,820 bp from pter      End:
242,576,864 bp from pter
Size:
53,045 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: THAP4_HUMAN, Q8WY91 (See protein sequence)
Recommended Name: THAP domain-containing protein 4  
Size: 577 amino acids; 62890 Da
Subunit: Homodimer (Probable)
Sequence caution: Sequence=AAH00247.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
Sequence=AAH09439.1; Type=Erroneous initiation; Note=Translation N-terminally extended; Sequence=BAA91560.1;
Type=Erroneous initiation; Note=Translation N-terminally extended;
1 PDB 3D structure from and Proteopedia for THAP4:
3IA8 (3D)    
Secondary accessions: Q53NU7 Q6GRN0 Q6IPJ3 Q9NW26 Q9Y325
Alternative splicing: 2 isoforms:  Q8WY91-1   Q8WY91-2   

Explore the universe of human proteins at neXtProt for THAP4: NX_Q8WY91

Explore proteomics data for THAP4 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q8WY91

  • THAP4 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    THAP4 Protein Expression
    REFSEQ proteins (2 alternative transcripts): 
    NP_001157828.1  NP_057047.4  

    ENSEMBL proteins: 
     ENSP00000385931   ENSP00000385006   ENSP00000384352  

    Human Recombinant Protein Products for THAP4: 
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    Novus Biologicals THAP4 Lysates
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    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for THAP4 


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    Novus Biologicals THAP4 Antibodies
    Abcam antibodies for THAP4
    Cloud-Clone Corp. Antibodies for THAP4 
    ThermoFisher Antibody for THAP4
    LSBio Antibodies in human, mouse, rat for THAP4 

    Assay Products for THAP4: 
    Browse Kits and Assays available from EMD Millipore
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    GenScript Custom Assay Services for THAP4
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for THAP4 
    Cloud-Clone Corp. CLIAs for THAP4


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    THAP: THAP (C2CH-type zinc finger) domain containing

    3 InterPro protein domains:
     IPR006612 Znf_C2CH
     IPR011038 Calycin-like
     IPR014878 DUF1794

    Graphical View of Domain Structure for InterPro Entry Q8WY91

    ProtoNet protein and cluster: Q8WY91

    UniProtKB/Swiss-Prot: THAP4_HUMAN, Q8WY91
    Similarity: Contains 1 THAP-type zinc finger


    THAP4 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

         Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003676nucleic acid binding ----
    GO:0003677DNA binding IEA--
    GO:0046872metal ion binding IEA--
         
    THAP4 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for THAP4:
     Decreased nuclei size in G2M 

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for THAP4 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for THAP4

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for THAP4 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for THAP4 

    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat THAP4
    4 QIAGEN miScript miRNA Assays for microRNAs that regulate THAP4:
    hsa-miR-3142 hsa-miR-659 hsa-miR-3157-5p hsa-miR-548c-3p
    SwitchGear 3'UTR luciferase reporter plasmidTHAP4 3' UTR sequence
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for THAP4
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat THAP4

    Gene Editing
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    Sirion Biotech Customized adenovirus for overexpression of THAP4

    Clone
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    Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene clones in human, mouse for THAP4 (see all 13)
    OriGene ORF clones in mouse, rat for THAP4
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    GenScript: all cDNA clones in your preferred vector (see all 2): THAP4 (NM_015963)
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat THAP4
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                         Customized lentivirus expression plasmids for stable overexpression of THAP4 

    Cell Line
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    Search LifeMap BioReagents cell lines for THAP4
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for THAP4


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for THAP4

    STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

    3 Interacting proteins for THAP4 (Q8WY912, 3 ENSP000003850064) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    MAPK6Q166592, 3MINT-8262077 I2D: score=2 
    MOB4Q9Y3A32, 3, ENSP000003157024MINT-65836 I2D: score=4 STRING: ENSP00000315702
    APCP250543I2D: score=2 
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for THAP4

    Search CenterWatch for drugs/clinical trials and news about THAP4

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for THAP4 gene (2 alternative transcripts): 
    NM_001164356.1  NM_015963.5  

    Unigene Cluster for THAP4:

    THAP domain containing 4
    Hs.435759  [show with all ESTs]
    Unigene Representative Sequence: NM_015963
    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000402136(uc002wbs.3) ENST00000407315(uc002wbt.3) ENST00000321679
    ENST00000402545 ENST00000497486
    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat THAP4
    4 QIAGEN miScript miRNA Assays for microRNAs that regulate THAP4:
    hsa-miR-3142 hsa-miR-659 hsa-miR-3157-5p hsa-miR-548c-3p
    SwitchGear 3'UTR luciferase reporter plasmidTHAP4 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for THAP4
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat THAP4
    Clone
    Products:
         
    OriGene clones in human, mouse for THAP4 (see all 13)
    OriGene ORF clones in mouse, rat for THAP4
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 2): THAP4 (NM_015963)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for THAP4
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat THAP4
    Sirion Biotech Customized lentivirus for stable overexpression of THAP4 
                         Customized lentivirus expression plasmids for stable overexpression of THAP4 
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for THAP4
    OriGene qSTAR qPCR primer pairs in human, mouse for THAP4
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat THAP4
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat THAP4
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat THAP4

    Additional mRNA sequence: 

    AF132970.1 AF258556.1 AK001216.1 AK225608.1 BC000247.1 BC000767.2 BC001842.2 BC009439.1 
    BC069235.1 BC071896.1 BC094822.1 

    15 DOTS entries:

    DT.86821254  DT.92444131  DT.120930212  DT.100806180  DT.95353131  DT.97847270  DT.218136  DT.92444139 
    DT.95353139  DT.95363915  DT.120930114  DT.92444132  DT.95353184  DT.100662509  DT.429722 

    24/335 AceView cDNA sequences (see all 335):

    BE622038 BM021904 BG287108 BU162469 BX375377 AI961301 CB161681 BQ960363 
    BU782671 BC069235 CD675131 BX383068 BM471597 AK001216 BF528421 AA335893 
    CB157744 BM981824 BC000767 BU734321 BE886067 BF345934 AI057007 BF529679 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    THAP4 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GCAACCACGA
    THAP4 Expression
    About this image


    See THAP4 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for THAP4

    SOURCE GeneReport for Unigene cluster: Hs.435759
        SABiosciences Custom PCR Arrays for THAP4
    Primer
    Products:
    OriGene qPCR primer pairs and template standards for THAP4
    OriGene qSTAR qPCR primer pairs in human, mouse for THAP4
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    QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat THAP4
    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat THAP4
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for THAP4

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for THAP4 gene from 9/16 species (see all 16)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Thap41 , 5 THAP domain containing 41, 5 84.51(n)1
    84.98(a)1
      1 (47.29 cM)5
    670261  NM_025920.31  NP_080196.31 
     937053915 
    chicken
    (Gallus gallus)
    Aves THAP41 THAP domain containing 4 71.41(n)
    71.53(a)
      429271  XM_003641747.1  XP_003641795.1 
    lizard
    (Anolis carolinensis)
    Reptilia THAP46
    Uncharacterized protein
    67(a)
    1 ↔ 1
    3(30506145-30534583)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.339742 Xenopus laevis transcribed sequence with weak similarity more 73.18(n)    BJ081834.1 
    zebrafish
    (Danio rerio)
    Actinopterygii wufb76g012 wufb76g01 72.01(n)   322910  57051134 
    mosquito
    (Anopheles gambiae)
    Insecta AgaP_AGAP0033131 AGAP003313-PA 55.84(n)
    43.95(a)
      1279785  XM_319543.3  XP_319543.2 
    worm
    (Caenorhabditis elegans)
    Secernentea T28H10.26
    C52G5.26
    (see all 4)
    Protein C52G5.2
    (see all 4)
    26(a)
    26(a)
    (see all 4)
    possible ortholog
    1 ↔ 1
    (see all 4)
    V(12510646-12512201)
    X(12843314-12845384)
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT1G792601 hypothetical protein 49.17(n)
    40.62(a)
      844266  NM_106576.3  NP_565204.1 
    rice
    (Oryza sativa)
    Liliopsida Os01g06796001 hypothetical protein 52.81(n)
    36.36(a)
      4325281  NM_001050402.1  NP_001043867.2 


    ENSEMBL Gene Tree for THAP4 (if available)
    TreeFam Gene Tree for THAP4 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/1268 SNPs in THAP4 are shown (see all 1268)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 2 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs2021806331,2
    --242523437(+) TTAAT-/TTCTTTTT 2 -- cds10--------
    rs347145511,2
    C--242523438(+) TAATT-/TCTTTTT 2 -- int10--------
    rs666280521,2
    C--242523439(+) AATTT-/CT/TC 
            
    TTTTT
    2 -- int10--------
    rs744416681,2
    C--242523440(+) AATTTC/TTTTTT 2 -- int12Minor allele frequency- T:0.25WA CSA 4
    rs2005776561,2
    --242523462(+) CAGAC-/AGAGTCT 2 -- int10--------
    rs1813523871,2
    --242523642(+) CTCCAC/TGTTGG 2 -- int10--------
    rs1854326041,2
    --242523801(+) AAAATG/TTACAG 2 -- int10--------
    rs1379146101,2
    --242523812(+) CCTACA/GCAAGT 2 -- int10--------
    rs1912593661,2
    --242523876(+) CTATGC/TCAGTA 2 -- ut310--------
    rs1496280621,2
    --242523907(+) TCTTGA/GGCCTG 2 -- ut310--------

    HapMap Linkage Disequilibrium report for THAP4 (242523820 - 242576864 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 10/17 variations for THAP4 (see all 17):    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2722013CNV Deletion23290073
    esv2722012CNV Deletion23290073
    esv2722011CNV Deletion23290073
    esv2662519CNV Deletion23128226
    esv2676442CNV Deletion23128226
    esv1008655CNV Deletion20482838
    esv1033771CNV Insertion17803354
    nsv508901CNV Insertion20534489
    dgv4493n71CNV Loss21882294
    dgv4496n71CNV Loss21882294

    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing THAP4
    DNA2.0 Custom Variant and Variant Library Synthesis for THAP4

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 612533    OMIM disorders: --

    2 diseases for THAP4:    About MalaCards
    tuberculosis    


    THAP4 for disorders           About GeneDecksing

    Genetic Association Database (GAD): THAP4

    Export disorders for THAP4 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for THAP4 gene, integrated from 9 sources (see all 16):
    (articles sorted by number of sources associating them with THAP4)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics. (PubMed id 10810093)1, 2, 3 Lai C.H....Lin W. (2000)
    2. Voxelwise genome-wide association study (vGWAS). (PubMed id 20171287)1, 4 Stein J.L....Thompson P. (2010)
    3. Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PubMed id 15815621)1, 2 Hillier L.W....Wilson R.K. (2005)
    4. Large-scale cDNA transfection screening for genes related to cancer development and progression. (PubMed id 15498874)1, 2 Wan D....Gu J. (2004)
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    6. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    7. The THAP domain: a novel protein motif with similarity to the DNA-binding domain of P element transposase. (PubMed id 12575992)1, 3 Roussigne M....Girard J.P. (2003)
    8. Identification of 23 new prostate cancer susceptibilit y loci using the iCOGS custom genotyping array. (PubMed id 23535732)1 Eeles R.A....Easton D.F. (2013)
    9. Quantitative analysis of HSP90-client interactions rev eals principles of substrate recognition. (PubMed id 22939624)1 Taipale M....Lindquist S. (2012)
    10. A directed protein interaction network for investigat ing intracellular signal transduction. (PubMed id 21900206)1 Vinayagam A....Wanker E.E. (2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 51078 HGNC: 23187 AceView: THAP4 Ensembl:ENSG00000176946 euGenes: HUgn51078
    ECgene: THAP4 H-InvDB: THAP4

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for THAP4 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for THAP4 gene:
    Search GeneIP for patents involving THAP4

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

     
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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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