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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

THAP3 Gene

protein-coding GIFtS: 47
GCID: GC01P006684

THAP domain containing, apoptosis associated protein 3

Search for THAP3
in

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
THAP Domain Containing, Apoptosis Associated Protein 3¹ ²
THAP Domain-Containing Protein 3²

External Ids:	HGNC: 20855¹	Entrez Gene: 90326²	Ensembl: ENSG00000041988⁷	OMIM: 612532⁵	UniProtKB: Q8WTV1³

Export aliases for THAP3 gene to outside databases

Previous GC identifers: GC00U909480 GC01P006620 GC01P006609 GC01P005832

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: THAP3_HUMAN, Q8WTV1

Function: Component of a THAP1/THAP3-HCFC1-OGT complex that is required for the regulation of the transcriptional

activity of RRM1

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000001.10 NC_018912.1 NT_021937.19

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the THAP3 gene promoter:
Spz1 AML1a MIF-1 Ik-3 E47 GATA-1 C/EBPalpha CHOP-10 PPAR-gamma1 PPAR-gamma2
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: THAP3 promoter sequence

Search SABiosciences Chromatin IP Primers for THAP3

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat THAP3

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1p36.31 Ensembl cytogenetic band: 1p36.31 HGNC cytogenetic band: 1p36.1

THAP3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
THAP3 gene location

GeneLoc information about chromosome 1 GeneLoc Exon Structure

GeneLoc location for GC01P006684: view genomic region (about GC identifiers)

Start:	6,684,926 bp from pter	End:	6,695,646 bp from pter
Size:	10,721 bases	Orientation:	plus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: THAP3_HUMAN, Q8WTV1 (See protein sequence)

Recommended Name: THAP domain-containing protein 3

Size: 239 amino acids; 27059 Da

Subunit: Component of a THAP1/THAP3-HCFC1-OGT complex that contains at least, either THAP1 or THAP3, HCFC1 and OGT.

Interacts directly with OGT and HCFC1 (via its HBM)

Secondary accessions: Q569K1 Q5TH66 Q5TH67 Q8N8T6 Q9BSC7 Q9Y3H2 Q9Y3H3

Alternative splicing: 3 isoforms: Q8WTV1-1 Q8WTV1-3 Q8WTV1-4 (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for THAP3: NX_Q8WTV1

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_Q8WTV1

THAP3 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins (3 alternative transcripts):

NP_001182681.1 NP_001182682.1 NP_612359.2

ENSEMBL proteins:

ENSP00000054650 ENSP00000311537 ENSP00000366854 ENSP00000465768 ENSP00000464954

Human Recombinant Protein Products for THAP3:

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	Uscn Proteins for THAP3

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Assay Products for THAP3:

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	GenScript Custom Assay Services for THAP3
	Browse Enzo Life Sciences for kits & assays
	Uscn ELISAs and CLIAs for THAP3

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

THAP3 for domains About GeneDecksing

2 InterPro domains/families:

IPR006612 Znf_C2CH

IPR026520 THAP3

Graphical View of Domain Structure for InterPro Entry Q8WTV1

ProtoNet protein and cluster: Q8WTV1

UniProtKB/Swiss-Prot: THAP3_HUMAN, Q8WTV1

Similarity: Contains 1 THAP-type zinc finger

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, Sirion Biotech, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, Sirion Biotech, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Molecular Function:

UniProtKB/Swiss-Prot Summary: THAP3_HUMAN, Q8WTV1

Function: Component of a THAP1/THAP3-HCFC1-OGT complex that is required for the regulation of the transcriptional

activity of RRM1

Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0003677	DNA binding	IEA	--
GO:0005515	protein binding	IPI	--
GO:0046872	metal ion binding	IEA	--

THAP3 for ontologies About GeneDecksing

Phenotypes:
3 GenomeRNAi human phenotypes for THAP3:

Decreased p24 protein expressi

Increased S DNA content

Increased cell number in G2M,

Animal Models:

inGenious Targeting Laboratory - Customizable classic, inducible, and humanized mouse model solutions for THAP3

miRNA Products:		OriGene 3'-UTR Clone: THAP3 Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat THAP3
		8/19 QIAGEN miScript miRNA Assays for microRNAs that regulate THAP3 (see all 19):
		hsa-miR-4254 hsa-miR-3200-5p hsa-miR-4251 hsa-miR-146a hsa-miR-340 hsa-miR-548a-3p hsa-miR-124 hsa-miR-3154

		SwitchGear 3'UTR luciferase reporter plasmid: THAP3 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for THAP3 (see all 7) OriGene shRNA RFP: THAP3 OriGene siRNA: THAP3
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		Sirion Biotech Custom design and validation of potent shRNA sequences against THAP3

Gene Editing Products:			DNA2.0 Custom Protein Engineering Service for THAP3
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		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for THAP3 (see all 6) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for THAP3 OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector (see all 3): THAP3 (NM_138350)
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		DNA2.0 Custom Codon Optimized Gene Synthesis Service for THAP3
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Cell Line Products:		GenScript Custom overexpressing Cell Line Services for THAP3
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		Sirion Biotech Customized stable knockdown cell line services for THAP3 Sirion Biotech Customized inducible knockdown cell line services for THAP3 Sirion Biotech Customized stable overexpressing cell line services for THAP3 Sirion Biotech Customized inducible overexpressing cell line services for THAP3

In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for THAP3

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for THAP3

STRING Interaction Network Preview (showing 3 interactants - click image to see more details)

3 Interacting proteins for THAP3 (Q8WTV1³ ENSP00000366854⁴) via UniProtKB, MINT, STRING, and/or I2D

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
HCFC1	P51610³, ENSP00000309555⁴	I2D: score=1 STRING: ENSP00000309555
OGT	O15294³, ENSP00000362824⁴	I2D: score=1 STRING: ENSP00000362824
UBC	ENSP00000344818⁴	STRING: ENSP00000344818

About this table

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for THAP3
Search CenterWatch for drugs/clinical trials and news about THAP3

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, Sirion Biotech, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for THAP3 gene (3 alternative transcripts):

NM_001195752.1 NM_001195753.1 NM_138350.3

Unigene Cluster for THAP3:

THAP domain containing, apoptosis associated protein 3

Hs.689006 [show with all ESTs]

Unigene Representative Sequence: NM_138350

8 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000054650(uc001aoc.3 uc001aod.3) ENST00000484676 ENST00000307896

ENST00000377627(uc001aoe.2) ENST00000484669 ENST00000487819 ENST00000472925

ENST00000480647

miRNA Products:		OriGene 3'-UTR Clone: THAP3 Browse OriGene MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat THAP3
		8/19 QIAGEN miScript miRNA Assays for microRNAs that regulate THAP3 (see all 19):
		hsa-miR-4254 hsa-miR-3200-5p hsa-miR-4251 hsa-miR-146a hsa-miR-340 hsa-miR-548a-3p hsa-miR-124 hsa-miR-3154

		SwitchGear 3'UTR luciferase reporter plasmid: THAP3 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for THAP3 (see all 7) OriGene shRNA RFP: THAP3 OriGene siRNA: THAP3
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat THAP3
		Sirion Biotech Custom design and validation of potent shRNA sequences against THAP3

Clone Products:		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for THAP3 (see all 6) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for THAP3 OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector (see all 3): THAP3 (NM_138350)
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for THAP3
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat THAP3

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for THAP3 Browse OriGene validated miRNA SYBR primer pairs
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		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat THAP3
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat THAP3

Additional cDNA sequence:

AF086370.1 AK096217.1 BC005114.1 BC022081.2 BC092427.1

13 DOTS entries:

DT.447625 DT.100653629 DT.99985402 DT.445231 DT.100758642 DT.91748007 DT.100795639 DT.92051561

DT.121331028 DT.75102383 DT.102832603 DT.40301323 DT.95322862

24/125 AceView cDNA sequences (see all 125):

BF448596 BX088984 BQ065768 BU857326 BU527489 CR620139 AI984347 BM687067

Z41901 AA235985 CR600833 BU190263 BM126658 BQ023670 BM675516 BE672540

AI967965 CA425222 CR609298 CR600561 BM691509 BQ681499 AW590484 AW269168

GeneLoc Exon Structure

5 Alternative Splicing Database (ASD) splice patterns (SP) for THAP3 About this scheme

ExUns:	1	^	2	^	3a	·	3b	^	4a	·	4b	^	5a	·	5b	^	6	^	7
SP1:			-		-								-
SP2:			-		-												-
SP3:			-		-								-
SP4:
SP5:

ECgene alternative splicing isoforms for THAP3

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

THAP3 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TGAGGGGGCT

About this image

THAP3 expression in embryonic tissues and stem cells
Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

1 LifeMap In Vivo Development Anatomical Compartment/Cell

Tissue

Anatomical Compartment

Cell

Category (developmental path)

Limb

Limb Bud

Limb Bud Mesenchyme Cells

Mesoderm

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

See THAP3 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for THAP3

SOURCE GeneReport for Unigene cluster: Hs.689006

UniProtKB/Swiss-Prot: THAP3_HUMAN, Q8WTV1

Tissue specificity: Highly expressed in heart, skeletal muscle and placenta. Weaker expression in brain, kidney and

liver

SABiosciences Custom PCR Arrays for THAP3

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for THAP3 Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT² qPCR Primer Assay in human, mouse / rat THAP3
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat THAP3
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat THAP3

In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for THAP3

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of chordates.

Orthologs for THAP3 gene from 1/8 species (see all 8) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
zebrafish (Danio rerio)	Actinopterygii	thap3¹	THAP domain containing, apoptosis associated protein more	50(n) 46.87(a)		541481 NM_001014294.1 NP_001014316.1

ENSEMBL Gene Tree for THAP3 (if available)
TreeFam Gene Tree for THAP3 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for THAP3 gene

THAP1² ENSG00000258064² THAP2² THAP5² THAP8²

3 SIMAP similar genes for THAP3 using alignment to 3 protein entries: THAP3_HUMAN (see all proteins):

THAP9 THAP1 THAP6

THAP3 for paralogs About GeneDecksing

1 Pseudogenes.org Pseudogene for THAP3
PGOHUM00000244826

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 1 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs190031755^1,2		--	6682929(+)	`CTGCTC/TGAGGG`	2	--	us2k¹ ut3¹		0	--	--	--	--
rs147028629^1,2		--	6682987(+)	`GCTCCA/GGCTTT`	2	--	us2k¹ ut3¹		0	--	--	--	--
rs74754875^1,2	F	--	6682998(+)	`CTCTGA/TAATGA`	2	--	ut3¹ us2k¹		1		WA	118
rs138309072^1,2		--	6683007(+)	`GAACAA/CTGCTC`	2	--	us2k¹ ut3¹		0	--	--	--	--
rs115877462^1,2		--	6683089(+)	`TTAAGG/ACATGG`	2	--	us2k¹ ut3¹		1		WA	118
rs55719565^1,2	C	--	6683134(+)	`TTCAGT/CGGGAT`	2	--	us2k¹ ut3¹		2		WA	120
rs192276638^1,2		--	6683147(+)	`GCCCGC/TGTTCT`	2	--	us2k¹ ut3¹		0	--	--	--	--
rs142416390^1,2		--	6683180(+)	`ATGTGG/TCACCT`	2	--	us2k¹ ut3¹		0	--	--	--	--
rs60457384^1,2	C	--	6683192(+)	`TGTGCC/TAGGCC`	2	--	us2k¹ ut3¹		2		WA	120
rs14057^1,2	C,F,O,A,H	--	6683240(+)	`CCAAGG/AGGCTT`	4	--	us2k¹ ut3¹		26		MN EA NS NA WA CSA	4215

HapMap Linkage Disequilibrium report for THAP3 (6684926 - 6695646 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for THAP3: --

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing THAP3

DNA2.0 Custom Variant and Variant Library Synthesis for THAP3

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

THAP3 for disorders About MalaCards

THAP3 for disorders About GeneDecksing

OMIM gene information: 612532 OMIM disorders: --

Human Genome Epidemiology (HuGE) Navigator: THAP3 (1 document)

Export disorders for THAP3 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for THAP3 gene integrated from 9 sources:
(articles sorted by number of sources associating them with THAP3)

Utopia: connect your pdf to the dynamic
world of online information

The THAP-zinc finger protein THAP1 associates with co activator HCF-1 and O-GlcNAc transferase: a link between DYT6 and DYT3 dystonia s. (PubMed id 20200153)^{1, 2} Mazars R....Girard J.P. (2010)
The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)^{1, 2} Gregory S.G.... Bentley D.R. (2006)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)^{1, 2} Ota T.... Sugano S. (2004)
The THAP domain: a novel protein motif with similarity to the DNA-binding domain of P element transposase. (PubMed id 12575992)^{1, 3} Roussigne M....Girard J.P. (2003)
Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)¹ Kim W....Gygi S.P. (2011)
Interactions of pathological hallmark proteins: tubul in polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PubMed id 21832049)¹ OlA!h J....OvA!di J. (2011)
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)¹ Strausberg R.L....Marra M.A. (2002)
Normalization and subtraction: two approaches to facilitate gene discovery. (PubMed id 8889548)¹ Bonaldo M.F.... Soares M.B. (1996)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

Entrez Gene: 90326	HGNC: 20855	AceView: MGC33488	Ensembl:ENSG00000041988	euGenes: HUgn90326
ECgene: THAP3	H-InvDB: THAP3

(According to HUGE)
About This Section

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for THAP3	Pharmacogenomics, SNPs, Pathways

Intellectual Property for THAP3 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

About This Section

Patent Information for THAP3 gene:
Search GeneIP for patents involving THAP3

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
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	Browse OriGene Antibodies		OriGene shRNA RFP for THAP3
	OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for THAP3		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for THAP3
	OriGene Protein Over-expression Lysate for THAP3		Browse OriGene Fluorogenic Cell Assay Kits
	OriGene siRNA for THAP3		OriGene 3'-UTR Clone for THAP3
	OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for THAP3		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for THAP3
	Browse OriGene GFP tagged cDNA clones in CMV expression vector		Browse OriGene MicroRNA Expression Plasmids
	Browse OriGene basic RS shRNAs		Browse OriGene validated miRNA SYBR primer pairs
	Browse OriGene full length recombinant human proteins expressed in human HEK293 cells		OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
	OriGene Custom Antibody Services for THAP3		OriGene Custom Protein Services for THAP3
	OriGene Custom Immunoassay Development

	QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat THAP3
	QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing THAP3
	QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat THAP3
	QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat THAP3
	QIAGEN QuantiFast Probe-based Assays in human, mouse, rat THAP3
	QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat THAP3

	GenScript Custom Purified and Recombinant Proteins Services for THAP3		GenScript cDNA clones with any tag delivered in your preferred vector for THAP3
	GenScript Custom Assay Services for THAP3		GenScript Custom Superior Antibodies Services for THAP3
	GenScript Custom overexpressing Cell Line Services for THAP3		CloneReady with Over 120,000 Genes
	Gene Synthesis: Any Gene in Any Vector		Vector-based siRNA and miRNA, Ready for Transfection
	Gene Mutant Library, Variants up to 10^11		Plasmid Preparation
	Custom Peptide Services

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	Regulatory tfbs in THAP3 promoter
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Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

	Novus Tissue Slides
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	Antibodies for THAP3
	See all of Abcam's Antibodies, Kits and Proteins for THAP3
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THAP3 Proteins, Antibodies, CLIAs, and ELISAs

Search LifeMap BioReagents cell lines for THAP3

	Gene Synthesis
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Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for THAP3

	SwitchGear 3'UTR luciferase reporter plasmids for THAP3
	SwitchGear Promoter luciferase reporter plasmids for THAP3

ThermoFisher Antibody for THAP3

Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat THAP3

inGenious Targeting Laboratory - Customizable classic, inducible, and humanized mouse model solutions for THAP3

Sirion Biotech Customized:

	stable knockdown cell line services for THAP3
	inducible knockdown cell line services for THAP3
	design and validation of potent shRNA sequences against THAP3
	adenovirus for potent knockdown of THAP3
	adenovirus for overexpression of THAP3
	stable overexpressing cell line services for THAP3
	inducible overexpressing cell line services for THAP3

GeneCards Homepage - Last full update: 18 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013 , 13 May 2013

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Category			VWF (GIFTS: 73) von Willebrand factor
GIFtS Group

The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

The GeneCards Human Gene Database

Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

Hot genes Disease genes THAP3 gene at Home site.

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THAP3 Gene

THAP domain containing, apoptosis associated protein 3

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THAP3 Gene

THAP domain containing, apoptosis associated protein 3

Aliasesfor THAP3 gene

Summariesfor THAP3 gene

Genomic Viewsfor THAP3 gene

Proteinsfor THAP3 gene

Protein Domains /Familiesfor THAP3 gene

Functionfor THAP3 gene

Pathways & Interactionsfor THAP3 gene

Drugs & Compoundsfor THAP3 gene

Transcriptsfor THAP3 gene

Expression for THAP3 gene

Orthologsfor THAP3 gene

Paralogsfor THAP3 gene

Genomic Variantsfor THAP3 gene

Disorders / Diseasesfor THAP3 gene

Publicationsfor THAP3 gene

External Searches for THAP3 gene

Genome Databases showing THAP3 gene

Other Databases showing THAP3 gene

Specialized Databases showing THAP3 gene

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Aliases
for THAP3 gene

Summaries
for THAP3 gene

Genomic Views
for THAP3 gene

Proteins
for THAP3 gene

Protein Domains /
Families
for THAP3 gene

Function
for THAP3 gene

Pathways & Interactions
for THAP3 gene

Drugs & Compounds
for THAP3 gene

Transcripts
for THAP3 gene

Expression
for THAP3 gene

Orthologs
for THAP3 gene

Paralogs
for THAP3 gene

Genomic Variants
for THAP3 gene

Disorders / Diseases
for THAP3 gene

Publications
for THAP3 gene

Intellectual Property
for THAP3 gene

Products
for THAP3 gene