THAP1 Gene
protein-coding GIFtS: 53
GCID: GC08M042691
|
|
THAP domain containing, apoptosis associated protein 1(Previous names: dystonia 6, torsion (autosomal dominant) )
(Previous symbol: DYT6)
| |
Aliases
for THAP1 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| THAP Domain Containing, Apoptosis Associated Protein 11 2 | | Dystonia 6, Torsion (Autosomal Dominant)1 | | DYT61 2 5 | | Nuclear Proapoptotic Factor2 | | 4833431A01Rik1 2 | | THAP Domain Protein 12 | | FLJ104771 | | THAP Domain-Containing Protein 12 |
Export aliases for THAP1 gene to outside databasesPrevious GC identifers: GC08M042432 GC08M042709 GC08M042810 GC08M041214 |
Summaries
for THAP1 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for THAP1:
The protein encoded by this gene contains a THAP domain, a conserved DNA-binding domain. This protein colocalizes withthe apoptosis response protein PAWR/PAR-4 in promyelocytic leukemia (PML) nuclear bodies, and functions as aproapoptotic factor that links PAWR to PML nuclear bodies. Alternatively spliced transcript variants encoding distinctisoforms have been observed. (provided by RefSeq, Jul 2008)
UniProtKB/Swiss-Prot: THAP1_HUMAN, Q9NVV9Function: DNA-binding transcription regulator that regulates endothelial cell proliferation and G1/S cell-cycleprogression. Specifically binds the 5'-[AT]NTNN[GT]GGCA[AGT]-3' core DNA sequence and acts by modulating expression ofpRB-E2F cell-cycle target genes, including RRM1. Component of a THAP1/THAP3-HCFC1-OGT complex that is required for theregulation of the transcriptional activity of RRM1. May also have pro-apoptopic activity by potentiating bothserum-withdrawal and TNF-induced apoptosis
Gene Wiki entry for THAP1
|
Genomic Views
for THAP1 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000008.10 NC_018919.1 NT_167187.1
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the THAP1 gene promoter:
AP-1 ATF-2 c-Jun GATA-1 RSRFC4
Other transcription factors
Search SABiosciences Chromatin IP Primers for THAP1
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat THAP1 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 8p11.21 Ensembl cytogenetic band: 8p11.21 HGNC cytogenetic band: 8p11.1THAP1 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 8 GeneLoc Exon Structure GeneLoc location for GC08M042691: view genomic region
(about GC identifiers)
Start:
|
42,691,817 bp from pter |
End:
|
42,698,474 bp from pter |
Size:
|
6,658 bases |
Orientation:
|
minus strand |
|
Proteins
for THAP1 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: THAP1_HUMAN, Q9NVV9 (See
protein sequence)Recommended Name: THAP domain-containing protein 1 Size: 213 amino acids; 24944 Da
Subunit: Interacts with PAWR. Component of a THAP1/THAP3-HCFC1-OGT complex that contains, either THAP1 or THAP3, HCFC1and OGT. Interacts with OGT. Interacts (via the HBM) with HCFC1 (via the Kelch-repeat domain); the interactionrecruits HCFC1 to the RRM1 promoter
Subcellular location: Nucleus, nucleoplasm. Nucleus, PML body
3 PDB 3D structures from  and Proteopedia  for THAP1:2JTG (3D)
2KO0 (3D)
2L1G (3D)
Secondary accessions: A6NCB6 D3DSY5 H9KV49 Q53FQ1 Q6IA99Alternative splicing: 2 isoforms: Q9NVV9-1 Q9NVV9-2 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for THAP1: NX_Q9NVV9
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9NVV9
THAP1 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (2 alternative transcripts):
NP_060575.1 NP_945354.1
ENSEMBL proteins: ENSP00000254250 ENSP00000344966 ENSP00000433912
Human Recombinant Protein Products:
Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table
THAP1 for ontologies About GeneDecksing
THAP1 Antibody Products:
Assay Products for THAP1: |
Protein
Domains /
Families
for THAP1 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
THAP1 for domains About GeneDecksing
2 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q9NVV9ProtoNet protein and cluster: Q9NVV9 UniProtKB/Swiss-Prot: THAP1_HUMAN, Q9NVV9Similarity: Belongs to the THAP1 familySimilarity: Contains 1 THAP-type zinc finger |
Function
for THAP1 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: THAP1_HUMAN, Q9NVV9Function: DNA-binding transcription regulator that regulates endothelial cell proliferation and G1/S cell-cycleprogression. Specifically binds the 5'-[AT]NTNN[GT]GGCA[AGT]-3' core DNA sequence and acts by modulating expression ofpRB-E2F cell-cycle target genes, including RRM1. Component of a THAP1/THAP3-HCFC1-OGT complex that is required for theregulation of the transcriptional activity of RRM1. May also have pro-apoptopic activity by potentiating bothserum-withdrawal and TNF-induced apoptosis
Clone
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OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for THAP1 (see all 3)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
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In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for THAP1 |
Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view): About this table
THAP1 for ontologies About GeneDecksing
1 GenomeRNAi human phenotype for THAP1:
|
Pathways & Interactions
for THAP1 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for THAP1
STRING Interaction
Network Preview (showing 5 interactants - click image to see 20)
5/555 Interacting proteins for THAP1 (Q9NVV92, 3 ENSP000002542504) via UniProtKB, MINT, STRING, and/or I2D (see all 555)| Interactant | Interaction Details |
|---|
| GeneCard | External ID(s) |
|---|
| GCOM1 | P0CAP12, 3, ENSP000003699434 | MINT-67488 I2D:
score=4 STRING: ENSP00000369943 | | AP2B1 | P630102, 3, ENSP000003144144 | MINT-67315 I2D:
score=5 STRING: ENSP00000314414 | | C1orf35 | Q9BU762, 3, ENSP000002721394 | MINT-66905 I2D:
score=5 STRING: ENSP00000272139 | | DVL2 | O146412, 3, ENSP000000053404 | MINT-68378 I2D:
score=5 STRING: ENSP00000005340 | | FXR2 | P511162, 3, ENSP000002501134 | MINT-66457 I2D:
score=5 STRING: ENSP00000250113 |
About this table
Gene Ontology (GO): 5 biological process terms (GO ID links to tree view): About this table
THAP1 for ontologies About GeneDecksing
|
Drugs & Compounds
for THAP1 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for THAP1
Search CenterWatch for drugs/clinical trials and news about THAP1
|
Transcripts
for THAP1 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for THAP1 gene (2 alternative transcripts): NM_018105.2 NM_199003.1 Unigene Cluster for THAP1: THAP domain containing, apoptosis associated protein 1 Hs.7432 [show with all ESTs]Unigene Representative Sequence: NM_0181054 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000254250(uc003xpk.3 uc003xpl.3) ENST00000345117 ENST00000529779
ENST00000532093
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for THAP1 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for THAP1 (see all 3)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 2): THAP1 (NM_018105) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for THAP1 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat THAP1 |
Additional cDNA sequence: AK001339.1 AK223231.1 AL832077.1 BC021721.2 CR457256.1 4 DOTS entries: DT.105920 DT.100022310 DT.95271442 DT.100716740 24/73 AceView cDNA sequences (see all 73): BM544773 BC021721 AL582975 CN482444 BI833227 AA278401 AA768676 BQ774093 BU178224 AI095609 CR607366 NM_199003 NM_018105 AI497677 AI475984 CA449343 CR457256 BP341562 BP337593 BG539776 BM680788 BE932253 AU126861 AL601225
GeneLoc Exon Structure
2 Alternative Splicing Database (ASD) splice patterns (SP) for THAP1 About this scheme
| ExUns: | 1a | · | 1b | ^ | 2 | ^ | 3a | · | 3b |
|---|
|
| SP1: | | | | | | | | | | | |
| SP2: | | | | | - | | | | | |
ECgene alternative splicing isoforms for THAP1
|
Expression
for THAP1 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| THAP1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GGCTCCTATT
About this image
See THAP1 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for THAP1
SOURCE GeneReport for Unigene cluster: Hs.7432
UniProtKB/Swiss-Prot: THAP1_HUMAN, Q9NVV9Tissue specificity: Highly expressed in heart, skeletal muscle, kidney and liver. Weaker expression in brain andplacenta
SABiosciences Custom PCR Arrays for THAP1
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for THAP1
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat THAP1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat THAP1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat THAP1 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for THAP1 |
Orthologs
for THAP1 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for THAP1 gene from 4/12 species (see all 12) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
THAP11 |
THAP domain containing, apoptosis associated protein more |
77(n)
81.69(a) |
|
431620 XM_429172.2 XP_429172.2 |
lizard
(Anolis carolinensis) |
Reptilia |
THAP16 |
-- |
77(a) |
1 ↔ 1 |
GL343339.1(850437-856006) |
African clawed frog
(Xenopus laevis) |
Amphibia |
Xl.35652 |
Xenopus laevis transcribed sequence with moderate similarity more |
75.77(n) |
|
BX845877.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
zgc:1365976 |
zgc:136597 |
44(a) |
1 ↔ 1 |
5(790771-798713) |
ENSEMBL Gene Tree for THAP1 (if available)
TreeFam Gene Tree for THAP1 (if available) |
Paralogs
for THAP1 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for THAP1 gene
- THAP32 ENSG000002580642 THAP22 THAP52 THAP82
4 SIMAP similar genes for THAP1 using alignment to 2 protein entries: THAP1_HUMAN (see all proteins):DKFZP564I0422 THAP3 THAP2 THAP8
THAP1 for paralogs About GeneDecksing
|
Genomic Variants
for THAP1 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 8 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for THAP1 (42691817 - 42698474 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for THAP1: --
Human Gene Mutation Database (HGMD): THAP1
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing THAP1 |
|
Disorders
/ Diseases
for THAP1 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
THAP1 for disorders About GeneDecksing
OMIM gene information: 609520
OMIM disorders: 602629
UniProtKB/Swiss-Prot: THAP1_HUMAN, Q9NVV9
Defects in THAP1 are the cause of dystonia type 6 (DYT6) [MIM:602629]. DYT6 is a primary torsion dystonia.Dystonia is defined by the presence of sustained involuntary muscle contractions, often leading to abnormal postures.Dystonia type 6 is characterized by onset in early adulthood, cranial or cervical involvement in about half of thecases, and frequent progression to involve multiple body regions
11  diseases for THAP1: About MalaCardsdystonia 6, torsion dystonia 6 dystonia musculorum deformans aicardi-goutieres syndrome
spasmodic dysphonia torsion dystonia familial dystonia blepharospasm
leukemia ataxia prostatitis
5 diseases from the University of Copenhagen DISEASES database for THAP1:Familial dystonia Movement disease Eyelid disease Deafness dystonia syndrome
Aicardi-Goutieres syndrome Human Genome Epidemiology (HuGE) Navigator: THAP1 (7 documents)
Export disorders for THAP1 gene to outside databases
|
Publications
for THAP1 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for THAP1 gene, integrated from 9 sources (see all 54):
(articles sorted by number of sources associating them with THAP1) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- THAP1 is a nuclear proapoptotic factor that links prostate-apoptosis- response-4 (Par-4) to PML nuclear bodies. (PubMed id 12717420)1, 2, 3, 9 Roussigne M.... Girard J.-P. (2003)
- Mutations in the THAP1 gene are responsible for DYT6 primary torsion dystonia. (PubMed id 19182804)1, 2, 3 Fuchs T.... Ozelius L.J. (2009)
- The THAP domain of THAP1 is a large C2CH module with zinc-dependent sequence-specific DNA-binding activity. (PubMed id 15863623)1, 2, 9 Clouaire T....Girard J.P. (2005)
- Genotype-phenotype correlations in THAP1 dystonia: Molecular foundations and description of new cases. (PubMed id 22377579)1, 2 Ledoux M.S.... Zhao Y. (2012)
- Novel THAP1 gene mutations in patients with primary dystonia from Southwest China. (PubMed id 21839475)1, 2 Song W.... Shang H.F. (2011)
- THAP1/DYT6 sequence variants in non-DYT1 early-onset primary dystonia in China and their effects on RNA expression. (PubMed id 21800139)1, 2 Cheng F.B....Wang L. (2011)
- Homozygous THAP1 mutations as cause of early-onset generalized dystonia. (PubMed id 21425335)1, 2 Schneider S.A.... Lohmann K. (2011)
- DYT6 dystonia: review of the literature and creation of the UMD Locus-Specific Database (LSDB) for mutations in the THAP1 gene. (PubMed id 21793105)1, 2 Blanchard A.... Collod-Beroud G. (2011)
- Identification and functional analysis of novel THAP1 mutations. (PubMed id 21847143)1, 2 Lohmann K.... Bruggemann N. (2011)
- Screening of the THAP1 gene in patients with early-on set dystonia: myoclonic jerks are part of the dystonia 6 phenotype. (PubMed id 21110056)1, 2 Clot F....Brice A. (2011)
|
External Searches for THAP1 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing THAP1 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing THAP1 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing THAP1 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
|
About This Section
| Patent Information for THAP1 gene:
Search GeneIP for patents involving THAP1
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for THAP1 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for THAP1 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for THAP1 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for THAP1 | | | OriGene Protein Over-expression Lysate for THAP1 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for THAP1 | | OriGene 3'-UTR Clone for THAP1 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for THAP1 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for THAP1 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for THAP1 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
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| |
 |
 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat THAP1 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing THAP1 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat THAP1 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat THAP1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat THAP1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat THAP1 |
| |
 |  |  |  | |
| | | | Search Tocris compounds for THAP1 |
| |  |  |  |  | | | | | | Recombinant Protein for THAP1 |
|
 |
 |
 |
 | | | THAP1 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for THAP1 |
|  |  |  | | | | Search ThermoFisher Antibodies for THAP1 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat THAP1 |
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