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Aliases for THA1P Gene

Aliases for THA1P Gene

  • Threonine Aldolase 1, Pseudogene 2 3 5
  • GLY1 3

External Ids for THA1P Gene

Previous GeneCards Identifiers for THA1P Gene

  • GC17M073757
  • GC17M076245
  • GC17M071669

Summaries for THA1P Gene

GeneCards Summary for THA1P Gene

THA1P (Threonine Aldolase 1, Pseudogene) is a Pseudogene.

Additional gene information for THA1P Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for THA1P Gene

Genomics for THA1P Gene

Regulatory Elements for THA1P Gene

Enhancers for THA1P Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH17H078250 1.8 FANTOM5 ENCODE dbSUPER 27.6 +3.3 3321 4.7 HDGF PKNOX1 MLX ARNT ZFP64 ARID4B SIN3A DMAP1 ZNF2 YY1 THA1P USP36 TMC8 SEPT9 TK1 AFMID TMC6 TMEM235 TNRC6C ENSG00000279886
GH17H078255 1.8 FANTOM5 Ensembl ENCODE dbSUPER 18.1 -1.5 -1510 4.3 HDGF PKNOX1 TCF12 GLIS2 CBX5 GATA2 ELK1 ATF7 RUNX3 ZNF592 THA1P PGS1 SOCS3 TK1 AFMID TMC8 TMC6 LINC01993 TNRC6C C17orf99
GH17H078261 1.6 Ensembl ENCODE dbSUPER 16.6 -6.8 -6826 2.7 PKNOX1 MLX ZFP64 ARID4B DMAP1 SLC30A9 ZNF766 ZNF592 KAT8 MEF2D USP36 THA1P TMEM235 SOCS3 PGS1 AFMID TK1 ENSG00000200063 LINC01993
GH17H078246 0.9 ENCODE dbSUPER 18.7 +8.7 8681 1.1 SOX13 SLC30A9 SAP130 MLX ARID4B RARA RXRB EGR2 THA1P AFMID TK1 LOC105371910 TMEM235
GH17H078241 1.8 FANTOM5 Ensembl ENCODE dbSUPER 9.1 +14.0 13980 1.6 HDGF PKNOX1 ATF1 FOXA2 ZFP64 ARID4B SLC30A9 ELK1 ZNF143 ATF7 THA1P TMEM235 SOCS3 TMC8 LOC105371910
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around THA1P on UCSC Golden Path with GeneCards custom track

Promoters for THA1P Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000098867 1785 801 HDGF PKNOX1 MLX ZFP64 ARID4B SIN3A DMAP1 YY1 SLC30A9 ZNF766

Genomic Locations for THA1P Gene

Genomic Locations for THA1P Gene
chr17:78,248,493-78,256,185
(GRCh38/hg38)
Size:
7,693 bases
Orientation:
Minus strand
chr17:76,244,574-76,252,266
(GRCh37/hg19)

Genomic View for THA1P Gene

Genes around THA1P on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
THA1P Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for THA1P Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for THA1P Gene

Proteins for THA1P Gene

Post-translational modifications for THA1P Gene

No Post-translational modifications

No data available for DME Specific Peptides for THA1P Gene

Domains & Families for THA1P Gene

Graphical View of Domain Structure for InterPro Entry

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for THA1P Gene

Function for THA1P Gene

Phenotypes From GWAS Catalog for THA1P Gene

Phenotypes for THA1P Gene

genes like me logo Genes that share phenotypes with THA1P: view

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for THA1P Gene

Localization for THA1P Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for THA1P Gene

Pathways & Interactions for THA1P Gene

SuperPathways for THA1P Gene

No Data Available

Interacting Proteins for THA1P Gene

Gene Ontology (GO) - Biological Process for THA1P Gene

None

No data available for Pathways by source and SIGNOR curated interactions for THA1P Gene

Drugs & Compounds for THA1P Gene

No Compound Related Data Available

Transcripts for THA1P Gene

mRNA/cDNA for THA1P Gene

(6) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for THA1P Gene

No ASD Table

Relevant External Links for THA1P Gene

GeneLoc Exon Structure for
THA1P
ECgene alternative splicing isoforms for
THA1P

Expression for THA1P Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for THA1P Gene

NURSA nuclear receptor signaling pathways regulating expression of THA1P Gene:

THA1P
genes like me logo Genes that share expression patterns with THA1P: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for THA1P Gene

Orthologs for THA1P Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for THA1P Gene

Organism Taxonomy Gene Similarity Type Details
wheat
(Triticum aestivum)
Liliopsida Ta.8615 33
Species where no ortholog for THA1P was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for THA1P Gene

ENSEMBL:
Gene Tree for THA1P (if available)
TreeFam:
Gene Tree for THA1P (if available)

Paralogs for THA1P Gene

No data available for Paralogs for THA1P Gene

Variants for THA1P Gene

Relevant External Links for THA1P Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
THA1P

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for THA1P Gene

Disorders for THA1P Gene

Relevant External Links for THA1P

Genetic Association Database (GAD)
THA1P

No disorders were found for THA1P Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for THA1P Gene

Publications for THA1P Gene

  1. Mice have a transcribed L-threonine aldolase/GLY1 gene, but the human GLY1 gene is a non-processed pseudogene. (PMID: 15757516) Edgar AJ (BMC genomics 2005) 2 3 22 60
  2. Identification and analysis of unitary pseudogenes: historic and contemporary gene losses in humans and other primates. (PMID: 20210993) Zhang ZD … Gerstein M (Genome biology 2010) 3 60
  3. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K … Sugano S (Genome research 2006) 3 60
  4. Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation. (PMID: 15146197) Brandenberger R … Stanton LW (Nature biotechnology 2004) 3 60
  5. Glycine metabolism in Candida albicans: characterization of the serine hydroxymethyltransferase (SHM1, SHM2) and threonine aldolase (GLY1) genes. (PMID: 10641038) McNeil JB … Pearlman RE (Yeast (Chichester, England) 2000) 22 60

Products for THA1P Gene

Sources for THA1P Gene

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