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Aliases for TGIF2-C20orf24 Gene

Aliases for TGIF2-C20orf24 Gene

  • TGIF2-C20orf24 Readthrough 2 3 5

External Ids for TGIF2-C20orf24 Gene

Previous GeneCards Identifiers for TGIF2-C20orf24 Gene

  • GC20P035203

Summaries for TGIF2-C20orf24 Gene

Entrez Gene Summary for TGIF2-C20orf24 Gene

  • This locus represents naturally occurring read-through transcription between the neighboring TGIF2 (TGFB-induced factor homeobox 2) and C20orf24 (chromosome 20 open reading frame 24) genes. The read-through transcript encodes a fusion protein that shares sequence identity with each individual gene product. [provided by RefSeq, Dec 2010]

GeneCards Summary for TGIF2-C20orf24 Gene

TGIF2-C20orf24 (TGIF2-C20orf24 Readthrough) is a Protein Coding gene. An important paralog of this gene is C20orf24.

Additional gene information for TGIF2-C20orf24 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TGIF2-C20orf24 Gene

Genomics for TGIF2-C20orf24 Gene

GeneHancer (GH) Regulatory Elements for TGIF2-C20orf24 Gene

Promoters and enhancers for TGIF2-C20orf24 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH20I036571 Promoter/Enhancer 2.3 EPDnew Ensembl ENCODE dbSUPER 550.8 -0.5 -528 5.5 HDGF PKNOX1 SMAD1 MLX ZFP64 ARID4B SIN3A FEZF1 DMAP1 IRF4 DLGAP4-AS1 TGIF2 TGIF2-C20orf24 SOGA1 MYL9 MANBAL AAR2
GH20I036604 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE 0.3 +32.1 32112 4.7 MLX ZFP64 DMAP1 IRF4 YY1 SLC30A9 E2F8 ZNF143 SP3 NFYC C20orf24 CPNE1 RBM39 RBM12 DSN1 MYL9 GC20M036587 TGIF2-C20orf24
GH20I036590 Enhancer 1.4 Ensembl ENCODE dbSUPER 0.4 +19.4 19400 6 HDGF ARID4B FEZF1 IRF4 GLIS2 ZNF207 ZNF143 FOS ATF7 RUNX3 SOGA1 GC20M036592 PIR43972 C20orf24 TGIF2-C20orf24 TGIF2 GC20M036587
GH20I036583 Enhancer 1.3 FANTOM5 ENCODE dbSUPER 0.4 +10.5 10520 3.7 INSM2 KLF17 SIN3A ZNF2 ZNF366 ZSCAN5C ZNF143 ATF7 FOS EGR2 C20orf24 MYL9 PIR36258 TGIF2 TGIF2-C20orf24
GH20I036587 Enhancer 0.8 ENCODE dbSUPER 0.4 +12.9 12933 0.1 NCOA3 ESRRA NFXL1 DPF2 ZKSCAN1 ZNF217 CTBP1 GATA3 MYC PIR36258 TGIF2 TGIF2-C20orf24
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around TGIF2-C20orf24 on UCSC Golden Path with GeneCards custom track

Genomic Locations for TGIF2-C20orf24 Gene

Genomic Locations for TGIF2-C20orf24 Gene
chr20:36,574,553-36,612,557
(GRCh38/hg38)
Size:
38,005 bases
Orientation:
Plus strand
chr20:35,202,956-35,240,960
(GRCh37/hg19)

Genomic View for TGIF2-C20orf24 Gene

Genes around TGIF2-C20orf24 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TGIF2-C20orf24 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TGIF2-C20orf24 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TGIF2-C20orf24 Gene

Proteins for TGIF2-C20orf24 Gene

  • Protein details for TGIF2-C20orf24 Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    A0A0A6YYL0
    Recommended name:
    Protein TGIF2-C20orf24
    Protein Accession:
    A0A0A6YYL0

    Protein attributes for TGIF2-C20orf24 Gene

    Size:
    155 amino acids
    Molecular mass:
    17908 Da
    Quaternary structure:
    No Data Available

neXtProt entry for TGIF2-C20orf24 Gene

Protein Expression for TGIF2-C20orf24 Gene

Post-translational modifications for TGIF2-C20orf24 Gene

No Post-translational modifications

Other Protein References for TGIF2-C20orf24 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for TGIF2-C20orf24 Gene

Domains & Families for TGIF2-C20orf24 Gene

Gene Families for TGIF2-C20orf24 Gene

Human Protein Atlas (HPA):
  • Predicted membrane proteins

Protein Domains for TGIF2-C20orf24 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with TGIF2-C20orf24: view

No data available for Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for TGIF2-C20orf24 Gene

Function for TGIF2-C20orf24 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for TGIF2-C20orf24 Gene

Localization for TGIF2-C20orf24 Gene

Gene Ontology (GO) - Cellular Components for TGIF2-C20orf24 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
GO:0005739 mitochondrion IEA --
GO:0016020 membrane IEA --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with TGIF2-C20orf24: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for TGIF2-C20orf24 Gene

Pathways & Interactions for TGIF2-C20orf24 Gene

SuperPathways for TGIF2-C20orf24 Gene

No Data Available

Interacting Proteins for TGIF2-C20orf24 Gene

Gene Ontology (GO) - Biological Process for TGIF2-C20orf24 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with TGIF2-C20orf24: view

No data available for Pathways by source and SIGNOR curated interactions for TGIF2-C20orf24 Gene

Drugs & Compounds for TGIF2-C20orf24 Gene

No Compound Related Data Available

Transcripts for TGIF2-C20orf24 Gene

mRNA/cDNA for TGIF2-C20orf24 Gene

(1) REFSEQ mRNAs :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for TGIF2-C20orf24 Gene

No ASD Table

Relevant External Links for TGIF2-C20orf24 Gene

GeneLoc Exon Structure for
TGIF2-C20orf24
ECgene alternative splicing isoforms for
TGIF2-C20orf24

Expression for TGIF2-C20orf24 Gene

Protein differential expression in normal tissues from HIPED for TGIF2-C20orf24 Gene

This gene is overexpressed in Platelet (52.3) and Heart (16.7).

Integrated Proteomics: protein expression in normal tissues and cell lines from PaxDb, MaxQB, and MOPED for TGIF2-C20orf24 Gene



Protein tissue co-expression partners for TGIF2-C20orf24 Gene

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for TGIF2-C20orf24 Gene

Orthologs for TGIF2-C20orf24 Gene

This gene was present in the common ancestor of animals.

Orthologs for TGIF2-C20orf24 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia TGIF2 34
  • 78 (a)
OneToOne
dog
(Canis familiaris)
Mammalia TGIF2-C20orf24 34
  • 78 (a)
OneToOne
cow
(Bos Taurus)
Mammalia RIP5 34
  • 78 (a)
OneToOne
mouse
(Mus musculus)
Mammalia 1110008F13Rik 34
  • 78 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia -- 34
  • 71 (a)
OneToMany
chicken
(Gallus gallus)
Aves C20H20ORF24 34
  • 65 (a)
OneToMany
lizard
(Anolis carolinensis)
Reptilia -- 34
  • 60 (a)
OneToMany
zebrafish
(Danio rerio)
Actinopterygii C23H20orf24 34
  • 65 (a)
OneToMany
fruit fly
(Drosophila melanogaster)
Insecta CG12107 34
  • 44 (a)
OneToMany
worm
(Caenorhabditis elegans)
Secernentea F44E7.9 34
  • 34 (a)
OneToMany
Species where no ortholog for TGIF2-C20orf24 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)

Evolution for TGIF2-C20orf24 Gene

ENSEMBL:
Gene Tree for TGIF2-C20orf24 (if available)
TreeFam:
Gene Tree for TGIF2-C20orf24 (if available)

Paralogs for TGIF2-C20orf24 Gene

Paralogs for TGIF2-C20orf24 Gene

genes like me logo Genes that share paralogs with TGIF2-C20orf24: view

Variants for TGIF2-C20orf24 Gene

Sequence variations from dbSNP and Humsavar for TGIF2-C20orf24 Gene

SNP ID Clin Chr 20 pos Variation AA Info Type
rs1000014129 -- 36,609,297(+) G/A intron_variant
rs1000139994 -- 36,604,693(+) C/G intron_variant
rs1000256939 -- 36,586,386(+) C/G intron_variant
rs1000416318 -- 36,580,339(+) G/A intron_variant
rs1000556837 -- 36,586,513(+) G/A intron_variant

Structural Variations from Database of Genomic Variants (DGV) for TGIF2-C20orf24 Gene

Variant ID Type Subtype PubMed ID
nsv1057192 CNV loss 25217958
nsv833967 CNV loss 17160897

Variation tolerance for TGIF2-C20orf24 Gene

Residual Variation Intolerance Score: 33.5% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.16; 3.57% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for TGIF2-C20orf24 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
TGIF2-C20orf24

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for TGIF2-C20orf24 Gene

Disorders for TGIF2-C20orf24 Gene

Additional Disease Information for TGIF2-C20orf24

No disorders were found for TGIF2-C20orf24 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for TGIF2-C20orf24 Gene

Publications for TGIF2-C20orf24 Gene

  1. Insights into RNA biology from an atlas of mammalian mRNA-binding proteins. (PMID: 22658674) Castello A … Hentze MW (Cell 2012) 3 58
  2. Expression of conjoined genes: another mechanism for gene regulation in eukaryotes. (PMID: 20967262) Prakash T … Taylor TD (PloS one 2010) 3 58
  3. RNA-binding activity of TRIM25 is mediated by its PRY/SPRY domain and is required for ubiquitination. (PMID: 29117863) Choudhury NR … Michlewski G (BMC biology 2017) 3

Products for TGIF2-C20orf24 Gene

Sources for TGIF2-C20orf24 Gene

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