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Aliases for TGIF2-C20orf24 Gene

Aliases for TGIF2-C20orf24 Gene

  • TGIF2-C20orf24 Readthrough 2 3 5

External Ids for TGIF2-C20orf24 Gene

Previous GeneCards Identifiers for TGIF2-C20orf24 Gene

  • GC20P035203

Summaries for TGIF2-C20orf24 Gene

Entrez Gene Summary for TGIF2-C20orf24 Gene

  • This locus represents naturally occurring read-through transcription between the neighboring TGIF2 (TGFB-induced factor homeobox 2) and C20orf24 (chromosome 20 open reading frame 24) genes. The read-through transcript encodes a fusion protein that shares sequence identity with each individual gene product. [provided by RefSeq, Dec 2010]

GeneCards Summary for TGIF2-C20orf24 Gene

TGIF2-C20orf24 (TGIF2-C20orf24 Readthrough) is a Protein Coding gene. An important paralog of this gene is C20orf24.

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TGIF2-C20orf24 Gene

Genomics for TGIF2-C20orf24 Gene

Regulatory Elements for TGIF2-C20orf24 Gene

Enhancers for TGIF2-C20orf24 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH20G036571 1.4 ENCODE dbSUPER 0.7 -0.5 -528 5.5 HDGF PKNOX1 FOXA2 MLX ZFP64 WRNIP1 ARID4B SIN3A FEZF1 DMAP1 MYL9 AAR2 TGIF2 TGIF2-C20orf24
GH20G036583 1.5 FANTOM5 ENCODE dbSUPER 0.4 +10.5 10521 3.7 ATF1 ZNF2 FOS ZNF592 ZSCAN16 GLIS1 KDM1A HNF4A WT1 SP7 C20orf24 MYL9 PIR36258 TGIF2-C20orf24
GH20G036577 1.3 ENCODE dbSUPER 0.4 +5.2 5175 3.8 FOXA2 ATF1 ARNT ARID4B SIN3A YY1 TCF12 GATA2 ZNF143 DEK MYL9 TGIF2-C20orf24 PIR36258
GH20G036588 0.9 ENCODE dbSUPER 0.4 +13.9 13858 0.8 SCRT1 RFX1 BHLHE40 NR2F1 RAD21 POLR2A IKZF1 SCRT2 RELB PIR36258 TGIF2-C20orf24
GH20G036587 0.9 ENCODE dbSUPER 0.4 +12.9 12933 0.1 ESRRA DPF2 ZKSCAN1 ZNF217 MBD2 RAD51 GATA3 CTBP1 MYC PIR36258 TGIF2-C20orf24
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around TGIF2-C20orf24 on UCSC Golden Path with GeneCards custom track

Promoters for TGIF2-C20orf24 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000136712 -354 2001 HDGF PKNOX1 MLX ZFP64 ARID4B SIN3A DMAP1 YY1 SLC30A9 ZNF143

Genomic Location for TGIF2-C20orf24 Gene

Chromosome:
20
Start:
36,574,553 bp from pter
End:
36,612,557 bp from pter
Size:
38,005 bases
Orientation:
Plus strand

Genomic View for TGIF2-C20orf24 Gene

Genes around TGIF2-C20orf24 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TGIF2-C20orf24 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TGIF2-C20orf24 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TGIF2-C20orf24 Gene

Proteins for TGIF2-C20orf24 Gene

  • Protein details for TGIF2-C20orf24 Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    A0A0A6YYL0
    Recommended name:
    Protein TGIF2-C20orf24
    Protein Accession:
    A0A0A6YYL0

    Protein attributes for TGIF2-C20orf24 Gene

    Size:
    155 amino acids
    Molecular mass:
    17908 Da
    Quaternary structure:
    No Data Available

neXtProt entry for TGIF2-C20orf24 Gene

Protein Expression for TGIF2-C20orf24 Gene

Post-translational modifications for TGIF2-C20orf24 Gene

No Post-translational modifications

Other Protein References for TGIF2-C20orf24 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for TGIF2-C20orf24 Gene

Domains & Families for TGIF2-C20orf24 Gene

Protein Domains for TGIF2-C20orf24 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with TGIF2-C20orf24: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for TGIF2-C20orf24 Gene

Function for TGIF2-C20orf24 Gene

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for TGIF2-C20orf24 Gene

Localization for TGIF2-C20orf24 Gene

Gene Ontology (GO) - Cellular Components for TGIF2-C20orf24 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
GO:0005739 mitochondrion IEA --
GO:0016020 membrane IEA --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with TGIF2-C20orf24: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Subcellular locations from COMPARTMENTS for TGIF2-C20orf24 Gene

Pathways & Interactions for TGIF2-C20orf24 Gene

SuperPathways for TGIF2-C20orf24 Gene

No Data Available

Interacting Proteins for TGIF2-C20orf24 Gene

Gene Ontology (GO) - Biological Process for TGIF2-C20orf24 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with TGIF2-C20orf24: view

No data available for Pathways by source and SIGNOR curated interactions for TGIF2-C20orf24 Gene

Drugs & Compounds for TGIF2-C20orf24 Gene

No Compound Related Data Available

Transcripts for TGIF2-C20orf24 Gene

mRNA/cDNA for TGIF2-C20orf24 Gene

(1) REFSEQ mRNAs :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for TGIF2-C20orf24 Gene

No ASD Table

Relevant External Links for TGIF2-C20orf24 Gene

GeneLoc Exon Structure for
TGIF2-C20orf24
ECgene alternative splicing isoforms for
TGIF2-C20orf24

Expression for TGIF2-C20orf24 Gene

Protein differential expression in normal tissues from HIPED for TGIF2-C20orf24 Gene

This gene is overexpressed in Platelet (52.3) and Heart (16.7).

Integrated Proteomics: protein expression in normal tissues and cell lines from PaxDb, MaxQB, and MOPED for TGIF2-C20orf24 Gene



Protein tissue co-expression partners for TGIF2-C20orf24 Gene

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for TGIF2-C20orf24 Gene

Orthologs for TGIF2-C20orf24 Gene

This gene was present in the common ancestor of animals.

Orthologs for TGIF2-C20orf24 Gene

Organism Taxonomy Gene Similarity Type Details
dog
(Canis familiaris)
Mammalia TGIF2-C20orf24 35
  • 78 (a)
OneToOne
mouse
(Mus musculus)
Mammalia 1110008F13Rik 35
  • 78 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia TGIF2 35
  • 78 (a)
OneToOne
cow
(Bos Taurus)
Mammalia RIP5 35
  • 78 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia -- 35
  • 71 (a)
OneToMany
chicken
(Gallus gallus)
Aves C20H20ORF24 35
  • 65 (a)
OneToMany
lizard
(Anolis carolinensis)
Reptilia -- 35
  • 60 (a)
OneToMany
zebrafish
(Danio rerio)
Actinopterygii C23H20orf24 35
  • 65 (a)
OneToMany
fruit fly
(Drosophila melanogaster)
Insecta CG12107 35
  • 44 (a)
OneToMany
worm
(Caenorhabditis elegans)
Secernentea F44E7.9 35
  • 34 (a)
OneToMany
Species where no ortholog for TGIF2-C20orf24 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)

Evolution for TGIF2-C20orf24 Gene

ENSEMBL:
Gene Tree for TGIF2-C20orf24 (if available)
TreeFam:
Gene Tree for TGIF2-C20orf24 (if available)

Paralogs for TGIF2-C20orf24 Gene

Paralogs for TGIF2-C20orf24 Gene

genes like me logo Genes that share paralogs with TGIF2-C20orf24: view

Variants for TGIF2-C20orf24 Gene

Sequence variations from dbSNP and Humsavar for TGIF2-C20orf24 Gene

SNP ID Clin Chr 20 pos Sequence Context AA Info Type
rs1000014129 -- 36,609,297(+) GCAGT(A/G)GAACA intron-variant
rs1000139994 -- 36,604,693(+) GATTG(C/G)CTGAG intron-variant, upstream-variant-2KB
rs1000256939 -- 36,586,386(+) GAAAT(C/G)ACTAA intron-variant
rs1000416318 -- 36,580,339(+) TGTAT(A/G)AGAAA intron-variant
rs1000556837 -- 36,586,513(+) AACAC(A/G)GTGAA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for TGIF2-C20orf24 Gene

Variant ID Type Subtype PubMed ID
nsv1057192 CNV loss 25217958
nsv833967 CNV loss 17160897

Variation tolerance for TGIF2-C20orf24 Gene

Residual Variation Intolerance Score: 33.5% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.16; 3.57% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for TGIF2-C20orf24 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
TGIF2-C20orf24

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for TGIF2-C20orf24 Gene

Disorders for TGIF2-C20orf24 Gene

Relevant External Links for TGIF2-C20orf24

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
TGIF2-C20orf24

No disorders were found for TGIF2-C20orf24 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for TGIF2-C20orf24 Gene

Publications for TGIF2-C20orf24 Gene

  1. Insights into RNA biology from an atlas of mammalian mRNA-binding proteins. (PMID: 22658674) Castello A. … Hentze M.W. (Cell 2012) 3 64
  2. Expression of conjoined genes: another mechanism for gene regulation in eukaryotes. (PMID: 20967262) Prakash T. … Taylor T.D. (PLoS ONE 2010) 3 64

Products for TGIF2-C20orf24 Gene

Sources for TGIF2-C20orf24 Gene

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