Aliases for TGFBRAP1 Gene
External Ids for TGFBRAP1 Gene
GeneCards Summary for TGFBRAP1 Gene
TGFBRAP1 (Transforming Growth Factor, Beta Receptor Associated Protein 1) is a Protein Coding gene. Among its related pathways are TGF-beta Receptor Signaling Pathway and SMAD Signaling Network. GO annotations related to this gene include SMAD binding and transforming growth factor beta receptor binding. An important paralog of this gene is VPS39.
UniProtKB/Swiss-Prot for TGFBRAP1 Gene
Plays a role in the TGF-beta/activin signaling pathway. It associates with inactive heteromeric TGF-beta and activin receptor complexes, mainly through the type II receptor, and is released upon activation of signaling. May recruit SMAD4 to the vicinity of the receptor complex and facilitate its interaction with receptor-regulated Smads, such as SMAD2.