Free for academic non-profit institutions. Other users need a Commercial license

Aliases for TGFBR3L Gene

Aliases for TGFBR3L Gene

  • Transforming Growth Factor Beta Receptor 3 Like 2 3 5
  • Transforming Growth Factor-Beta Receptor Type III-Like Protein 3 4
  • Transforming Growth Factor, Beta Receptor III-Like 2 3
  • TGF-Beta Receptor Type III-Like Protein 3 4
  • TGF-Beta Receptor Type-3-Like Protein 3 4
  • TGFR-3L 3 4
  • Transforming Growth Factor-Beta Receptor Type 3-Like Protein 3

External Ids for TGFBR3L Gene

Previous GeneCards Identifiers for TGFBR3L Gene

  • GC19P007982

Summaries for TGFBR3L Gene

GeneCards Summary for TGFBR3L Gene

TGFBR3L (Transforming Growth Factor Beta Receptor 3 Like) is a Protein Coding gene. An important paralog of this gene is TGFBR3.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TGFBR3L Gene

Genomics for TGFBR3L Gene

Regulatory Elements for TGFBR3L Gene

Enhancers for TGFBR3L Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
- Elite enhancer/Elite enhancer-gene association

Enhancers around TGFBR3L on UCSC Golden Path with GeneCards custom track

Promoters for TGFBR3L Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

Genomic Location for TGFBR3L Gene

7,915,455 bp from pter
7,919,097 bp from pter
3,643 bases
Plus strand

Genomic View for TGFBR3L Gene

Genes around TGFBR3L on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TGFBR3L Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TGFBR3L Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TGFBR3L Gene

Proteins for TGFBR3L Gene

  • Protein details for TGFBR3L Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Transforming growth factor-beta receptor type 3-like protein
    Protein Accession:

    Protein attributes for TGFBR3L Gene

    316 amino acids
    Molecular mass:
    32819 Da
    Quaternary structure:
    No Data Available

neXtProt entry for TGFBR3L Gene

Post-translational modifications for TGFBR3L Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for TGFBR3L Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for TGFBR3L Gene

Domains & Families for TGFBR3L Gene

Protein Domains for TGFBR3L Gene


Graphical View of Domain Structure for InterPro Entry



  • Contains 1 ZP domain.
  • Contains 1 ZP domain.
genes like me logo Genes that share domains with TGFBR3L: view

No data available for Gene Families and Suggested Antigen Peptide Sequences for TGFBR3L Gene

Function for TGFBR3L Gene

Phenotypes for TGFBR3L Gene

GenomeRNAi human phenotypes for TGFBR3L:
genes like me logo Genes that share phenotypes with TGFBR3L: view

Animal Model Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for TGFBR3L Gene

Localization for TGFBR3L Gene

Subcellular locations from UniProtKB/Swiss-Prot for TGFBR3L Gene

Membrane; Single-pass membrane protein.

Gene Ontology (GO) - Cellular Components for TGFBR3L Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with TGFBR3L: view

No data available for Subcellular locations from COMPARTMENTS for TGFBR3L Gene

Pathways & Interactions for TGFBR3L Gene

SuperPathways for TGFBR3L Gene

No Data Available

Interacting Proteins for TGFBR3L Gene

Gene Ontology (GO) - Biological Process for TGFBR3L Gene


No data available for Pathways by source and SIGNOR curated interactions for TGFBR3L Gene

Drugs & Compounds for TGFBR3L Gene

No Compound Related Data Available

Transcripts for TGFBR3L Gene

mRNA/cDNA for TGFBR3L Gene

(6) REFSEQ mRNAs :
(0) Additional mRNA sequences :
(3) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for TGFBR3L Gene

Transforming growth factor, beta receptor III-like:
Representative Sequences:

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for TGFBR3L Gene

No ASD Table

Relevant External Links for TGFBR3L Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for TGFBR3L Gene

mRNA expression in normal human tissues for TGFBR3L Gene

mRNA differential expression in normal tissues according to GTEx for TGFBR3L Gene

This gene is overexpressed in Pituitary (x32.9).

Protein differential expression in normal tissues from HIPED for TGFBR3L Gene

This gene is overexpressed in Bone (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for TGFBR3L Gene

Protein tissue co-expression partners for TGFBR3L Gene

NURSA nuclear receptor signaling pathways regulating expression of TGFBR3L Gene:


SOURCE GeneReport for Unigene cluster for TGFBR3L Gene:

genes like me logo Genes that share expression patterns with TGFBR3L: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for TGFBR3L Gene

Orthologs for TGFBR3L Gene

This gene was present in the common ancestor of chordates.

Orthologs for TGFBR3L Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia TGFBR3L 34
  • 85.71 (n)
  • 83.78 (a)
-- 35
  • 12 (a)
(Mus musculus)
Mammalia Gm14378 34
  • 77.38 (n)
  • 80.16 (a)
Tgfbr3l 16
Gm14378 35
  • 67 (a)
(Pan troglodytes)
Mammalia TGFBR3L 34
  • 96.91 (n)
  • 95.85 (a)
(Rattus norvegicus)
Mammalia Tgfbr3l 34
  • 77.03 (n)
  • 80.71 (a)
(Anolis carolinensis)
Reptilia TGFBR3L 35
  • 25 (a)
(Danio rerio)
Actinopterygii CABZ01064405.1 35
  • 8 (a)
Species where no ortholog for TGFBR3L was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for TGFBR3L Gene

Gene Tree for TGFBR3L (if available)
Gene Tree for TGFBR3L (if available)

Paralogs for TGFBR3L Gene

Paralogs for TGFBR3L Gene

genes like me logo Genes that share paralogs with TGFBR3L: view

Variants for TGFBR3L Gene

Sequence variations from dbSNP and Humsavar for TGFBR3L Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type
rs77927328 -- 7,915,442(+) GGGGG(C/T)CAGTC upstream-variant-2KB
rs11883160 -- 7,915,192(+) CTGGT(C/G)TCGAA upstream-variant-2KB
rs8107424 -- 7,918,041(+) CAGCT(C/T)GCCTC intron-variant, downstream-variant-500B
rs114344141 -- 7,915,996(+) AGCAC(C/T)TATCT upstream-variant-2KB, utr-variant-5-prime
rs532309486 -- 7,915,606(+) GGTAG(C/G)GAGTG upstream-variant-2KB, utr-variant-5-prime

Structural Variations from Database of Genomic Variants (DGV) for TGFBR3L Gene

Variant ID Type Subtype PubMed ID
nsv833733 CNV gain 17160897
nsv953961 CNV deletion 24416366

Variation tolerance for TGFBR3L Gene

Gene Damage Index Score: 2.39; 42.33% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for TGFBR3L Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for TGFBR3L Gene

Disorders for TGFBR3L Gene

Relevant External Links for TGFBR3L

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for TGFBR3L Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for TGFBR3L Gene

Publications for TGFBR3L Gene

  1. Discovery of 342 putative new genes from the analysis of 5'-end- sequenced full-length-enriched cDNA human transcripts. (PMID: 15885500) Dalla E. … Schneider C. (Genomics 2005) 3 4 65
  2. The DNA sequence and biology of human chromosome 19. (PMID: 15057824) Grimwood J. … Lucas S.M. (Nature 2004) 4 65
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4 65

Products for TGFBR3L Gene

Sources for TGFBR3L Gene

Loading form....