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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

TGDS Gene

protein-coding   GIFtS: 51
GCID: GC13M095226

TDP-Glucose 4,6-Dehydratase

  See related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
TDP-Glucose 4,6-Dehydratase1 2     DTDP-D-Glucose 4,6-Dehydratase2
Member 11     Growth-Inhibiting Protein 212
Short Chain Dehydrogenase/Reductase Family 2E1     Short Chain Dehydrogenase/Reductase Family 2E, Member 12
SDR2E12     EC 4.2.1.463
TDPGD2     P5

External Ids:    HGNC: 203241   Entrez Gene: 234832   Ensembl: ENSG000000884517   OMIM: 1768035   UniProtKB: O954553   

Export aliases for TGDS gene to outside databases

Previous GC identifers: GC13M094062 GC13M092924 GC13M094024 GC13M075823


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for TGDS Gene: 
TGDS (TDP-glucose 4,6-dehydratase) is a protein-coding gene. Diseases associated with TGDS include tuberculosis, and among its related super-pathways are Metabolism. GO annotations related to this gene include dTDP-glucose 4,6-dehydratase activity and nucleotide binding. An important paralog of this gene is UXS1.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000013.10  NC_018924.2  NT_009952.14  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the TGDS gene promoter:
         SRF   GR   SRF (504 AA)   PPAR-gamma1   GCNF-1   PPAR-gamma2   GR-alpha   GCNF-2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidTGDS promoter sequence
   Search SABiosciences Chromatin IP Primers for TGDS

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TGDS


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 13q32.1   Ensembl cytogenetic band:  13q32.1   HGNC cytogenetic band: 13q32.1

TGDS Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TGDS gene location

GeneLoc information about chromosome 13         GeneLoc Exon Structure

GeneLoc location for GC13M095226:  view genomic region     (about GC identifiers)

Start:
95,226,308 bp from pter      End:
95,248,511 bp from pter
Size:
22,204 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: TGDS_HUMAN, O95455 (See protein sequence)
Recommended Name: dTDP-D-glucose 4,6-dehydratase  
Size: 350 amino acids; 40214 Da
Cofactor: NAD (By similarity)
Secondary accessions: Q5T3Z2 Q9H1T9

Explore the universe of human proteins at neXtProt for TGDS: NX_O95455

Explore proteomics data for TGDS at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_O95455

  • TGDS Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    TGDS Protein Expression
    REFSEQ proteins: NP_055120.1  
    ENSEMBL proteins: 
     ENSP00000261296  

    Human Recombinant Protein Products for TGDS: 
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    Novus Biologicals TGDS Protein
    Novus Biologicals TGDS Lysates
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    Browse Sino Biological Cell Lysates 
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    Cloud-Clone Corp. Proteins for TGDS 


    TGDS Antibody Products: 
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    Cloud-Clone Corp. Antibodies for TGDS 
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    LSBio Antibodies in human, mouse, rat for TGDS 

    Assay Products for TGDS: 
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    Cloud-Clone Corp. ELISAs for TGDS 
    Cloud-Clone Corp. CLIAs for TGDS


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    SDRE: Short chain dehydrogenase/reductase superfamily / Extended SDR fold

    3 InterPro protein domains:
     IPR001509 Epimerase_deHydtase
     IPR005888 dTDP_Gluc_deHydtase
     IPR016040 NAD(P)-bd_dom

    Graphical View of Domain Structure for InterPro Entry O95455

    ProtoNet protein and cluster: O95455

    1 Blocks protein domain: IPB001509 NAD-dependent epimerase/dehydratase

    UniProtKB/Swiss-Prot: TGDS_HUMAN, O95455
    Similarity: Belongs to the sugar epimerase family. dTDP-glucose dehydratase subfamily


    TGDS for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: TGDS_HUMAN, O95455
    Catalytic activity: dTDP-alpha-D-glucose = dTDP-4-dehydro-6-deoxy-alpha-D-glucose + H(2)O

         Enzyme Number (IUBMB): EC 4.2.1.461

         Gene Ontology (GO): 5/6 molecular function terms (GO ID links to tree view) (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003824catalytic activity ----
    GO:00038543-beta-hydroxy-delta5-steroid dehydrogenase activity ----
    GO:0008460dTDP-glucose 4,6-dehydratase activity IEA--
    GO:0008831dTDP-4-dehydrorhamnose reductase activity ----
    GO:0016616oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor ----
         
    TGDS for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for TGDS:
     Increased gamma-H2AX phosphory 

         1 MGI phenotypic allele for Tgds (no phenotypes)

    TGDS for phenotypes           About GeneDecksing

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for TGDS 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for TGDS

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for TGDS 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for TGDS 

    miRNA
    Products:
        
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat TGDS
    8/15 QIAGEN miScript miRNA Assays for microRNAs that regulate TGDS (see all 15):
    hsa-miR-579 hsa-miR-98 hsa-miR-548am hsa-let-7d hsa-let-7c hsa-miR-340 hsa-let-7i hsa-let-7g
    SwitchGear 3'UTR luciferase reporter plasmidTGDS 3' UTR sequence
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
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    Gene Editing
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    Clone
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                         Customized lentivirus expression plasmids for stable overexpression of TGDS 

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    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TGDS


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for TGDS About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Metabolism
    Metabolic pathways0.40

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways



    1         Kegg Pathway  (Kegg details for TGDS):
        Metabolic pathways


    TGDS for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for TGDS

    STRING Interaction Network Preview (showing 4 interactants - click image to see more details)

    5 Interacting proteins for TGDS (O954553 ENSP000002612964) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    PIK3R1P279863, ENSP000002743354I2D: score=1 STRING: ENSP00000274335
    NCK1P163333, ENSP000002889864I2D: score=1 STRING: ENSP00000288986
    RBL1P287493I2D: score=1 
    UBCENSP000003448184STRING: ENSP00000344818
    CLPXENSP000003001074STRING: ENSP00000300107
    About this table

    Gene Ontology (GO): 5/6 biological process terms (GO ID links to tree view) (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006694steroid biosynthetic process ----
    GO:0009058biosynthetic process ----
    GO:0009225nucleotide-sugar metabolic process IEA--
    GO:0044237cellular metabolic process ----
    GO:0045226extracellular polysaccharide biosynthetic process ----

    TGDS for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for TGDS

    6 HMDB Compounds for TGDS    About this table
    CompoundSynonyms CAS #PubMed Ids
    4,6-Dideoxy-4-oxo-dTDP-D-glucose4,6-Dideoxy-4-oxo-dTDP-D-glucose (see all 9)----
    NAD3-Carbamoyl-1-D-ribofuranosylpyridinium hydroxide 5'-ester with adenosine 5'-pyrophosphate (see all 28)53-84-9--
    NADH1,4-Dihydronicotinamide adenine dinucleotide (see all 17)58-68-4--
    WaterDihydrogen oxide (see all 2)7732-18-5--
    dTDPDeoxy-tdp (see all 5)491-97-4--
    dTDP-D-glucoseMono-a-D-glucopyranosyl ester (see all 13)2196-62-5--

    Search CenterWatch for drugs/clinical trials and news about TGDS

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for TGDS gene: 
    NM_014305.2  

    Unigene Cluster for TGDS:

    TDP-glucose 4,6-dehydratase
    Hs.12393  [show with all ESTs]
    Unigene Representative Sequence: NM_014305
    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000261296(uc001vlw.3) ENST00000498294 ENST00000470480
    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat TGDS
    8/15 QIAGEN miScript miRNA Assays for microRNAs that regulate TGDS (see all 15):
    hsa-miR-579 hsa-miR-98 hsa-miR-548am hsa-let-7d hsa-let-7c hsa-miR-340 hsa-let-7i hsa-let-7g
    SwitchGear 3'UTR luciferase reporter plasmidTGDS 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for TGDS
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TGDS
    Clone
    Products:
         
    OriGene clones in human, mouse for TGDS (see all 7)
    OriGene ORF clones in mouse, rat for TGDS
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: TGDS (NM_000954)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TGDS
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TGDS
    Sirion Biotech Customized lentivirus for stable overexpression of TGDS 
                         Customized lentivirus expression plasmids for stable overexpression of TGDS 
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for TGDS
    OriGene qSTAR qPCR primer pairs in human, mouse for TGDS
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat TGDS
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TGDS
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TGDS

    Additional mRNA sequence: 

    AF048686.1 AF339778.1 AJ006068.1 AK303439.1 AK313251.1 AY544125.1 BC005284.1 BC033675.1 

    7 DOTS entries:

    DT.442855  DT.100712436  DT.120762296  DT.303955  DT.92427708  DT.99976687  DT.40283582 

    24/145 AceView cDNA sequences (see all 145):

    AI347251 AV685357 AI972505 BP350999 BU688902 BX109198 AA171681 AI539664 
    BC033675 AA367325 BP374487 AA776218 F10590 BI914642 BE301796 BI765488 
    CR606771 AA668890 AA307446 AA424821 AI683375 AI923250 AA296374 AI868932 

    GeneLoc Exon Structure

    3 Alternative Splicing Database (ASD) splice patterns (SP) for TGDS    About this scheme

    ExUns: 1a · 1b · 1c · 1d ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7a · 7b ^ 8 ^ 9 ^ 10 ^ 11 ^ 12
    SP1:                    -                                                                           
    SP2:                                                                                                
    SP3:                                      -                                                         


    ECgene alternative splicing isoforms for TGDS

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TGDS expression in normal human tissues (normalized intensities)      TGDS embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TTTACTGTTT
    TGDS Expression
    About this image


    TGDS expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/13 selected tissues (see all 13) fully expand
     
     Bone (Muscoskeletal System)    fully expand to see all 2 entries
             Membranous Facial Bones
             skeleton/cranium   
     
     Heart (Cardiovascular System)    fully expand to see all 2 entries
             heart/atrium   
     
     Brain (Nervous System)    fully expand to see all 2 entries
             Cerebral Cortex
             brain/forebrain/telencephalon   
     
     Neural Crest (Gastrulation Derivatives)
             skeleton/cranium   
     
     Gut Tube (Gastrointestinal Tract)
             Foregut

    See TGDS Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for TGDS

    SOURCE GeneReport for Unigene cluster: Hs.12393
        SABiosciences Custom PCR Arrays for TGDS
    Primer
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    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TGDS
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TGDS

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for TGDS gene from 7/14 species (see all 14)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Tgds1 , 5 TDP-glucose 4,6-dehydratase1, 5 86.57(n)1
    91.14(a)1
      14 (61.74 cM)5
    763551  NM_029578.31  NP_083854.31 
     1181119115 
    chicken
    (Gallus gallus)
    Aves TGDS1 TDP-glucose 4,6-dehydratase 80.9(n)
    87.16(a)
      418793  XM_416988.3  XP_416988.1 
    lizard
    (Anolis carolinensis)
    Reptilia TGDS6
    Uncharacterized protein
    78(a)
    1 ↔ 1
    3(84760667-84789601)
    zebrafish
    (Danio rerio)
    Actinopterygii wufi14g092 wufi14g09 70.01(n)   327507  BC049462.1 
    worm
    (Caenorhabditis elegans)
    Secernentea F53B1.46
    C01F1.36
    Protein C01F1.3, isoform a
    35(a)
    16(a)
    many → 1
    many → 1
    X(2111778-2113084)
    II(4295101-4299211)
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes GAL106
    UDP-glucose-4-epimerase, catalyzes the interconver...
    12(a)
    1 → many
    II(276253-278352)
    rice
    (Oryza sativa)
    Liliopsida AK103544.12   -- 76.34(n)    AK103544.1 


    ENSEMBL Gene Tree for TGDS (if available)
    TreeFam Gene Tree for TGDS (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for TGDS gene
    UXS12  GALE2  

    TGDS for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/532 SNPs in TGDS are shown (see all 532)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 13 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs586916341,2
    C--76149501(+) AAAAA-/AA/AG 
            
    GAAAA
    1 -- int10--------
    rs1907478111,2
    --95225852(+) CTCCAC/TTGGGC 1 -- int10--------
    rs587522391,2
    C,F--95225916(+) ACATGG/CGTTGG 1 -- int14Minor allele frequency- C:0.12WA CSA NA 241
    rs596441481,2
    C--95225976(+) TTATCG/ATTATA 1 -- int13Minor allele frequency- A:0.33WA CSA 121
    rs1834544271,2
    --95225993(+) ACTTTC/TTCTCT 1 -- int10--------
    rs1454062231,2
    --95226161(+) CTTTCC/TAATGA 1 -- int10--------
    rs1862662191,2
    --95226206(+) CTTAAC/TAGAGG 1 -- int10--------
    rs73224531,2
    C,F,A,H--95226210(+) ATAGAG/CGGCCA 1 -- int112Minor allele frequency- C:0.33NS EA NA WA CSA 660
    rs1920319781,2
    --95226318(+) TCAAAA/TTTTTT 1 -- ut310--------
    rs1476679791,2
    --95226353(+) AACATC/TATTTT 1 -- ut310--------

    HapMap Linkage Disequilibrium report for TGDS (95226308 - 95248511 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 4 variations for TGDS:    About this table     
    Variant IDTypeSubtypePubMed ID
    esv34004CNV Loss18971310
    nsv819312CNV Loss19587683
    nsv832686CNV Gain17160897
    nsv832685CNV Gain17160897

    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing TGDS
    DNA2.0 Custom Variant and Variant Library Synthesis for TGDS

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 176803    OMIM disorders: --

    2 diseases for TGDS:    About MalaCards
    tuberculosis    


    TGDS for disorders           About GeneDecksing


    Export disorders for TGDS gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for TGDS gene integrated from 9 sources:
    (articles sorted by number of sources associating them with TGDS)
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    world of online information

    1. The SDR (short-chain dehydrogenase/reductase and related enzymes) nomenclature initiative. (PubMed id 19027726)1, 3 Persson B.... Oppermann U. (2009)
    2. The DNA sequence and analysis of human chromosome 13. (PubMed id 15057823)1, 2 Dunham A.... Ross M.T. (2004)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    4. Protein interaction discovery using parallel analysis of translated ORFs (PLATO). (PubMed id 23503679)1 Zhu J....Elledge S.J. (2013)
    5. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
    6. Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)
    7. Global identification of modular cullin-RING ligase su bstrates. (PubMed id 21963094)1 Emanuele M.J....Elledge S.J. (2011)
    8. Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening. (PubMed id 17474147)1 Wu C....Li S.S. (2007)
    9. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
    10. Hepatitis C virus core protein interacts with 14-3-3 protein and activates the kinase Raf-1. (PubMed id )2 Aoki H.... Hino O. (2000)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 23483 HGNC: 20324 AceView: TGDS Ensembl:ENSG00000088451 euGenes: HUgn23483
    ECgene: TGDS Kegg: 23483 H-InvDB: TGDS

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for TGDS Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for TGDS gene:
    Search GeneIP for patents involving TGDS

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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